Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity

Diabetologia

Volumn 60, Issue 3, 2017, Pages 424-431

  Honkanen, Hanna ^a   Oikarinen, Sami ^a,b   Nurminen, Noora ^a   Laitinen, Olli H ^a,c   Huhtala, Heini ^a   Lehtonen, Jussi ^a   Ruokoranta, Tanja ^c   Hankaniemi, Minna M ^a,c   Lecouturier, Valérie ^d   Almond, Jeffrey W ^d   Tauriainen, Sisko ^e   Simell, Olli ^f,g   Ilonen, Jorma ^e   Veijola, Riitta ^h   Viskari, Hanna ^a,i   Knip, Mikael ^i,j,k,l   Hyöty, Heikki ^a,b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b PIRKANMAA HOSPITAL DISTRICT   (Finland)

^c Vactech Ltd   (Finland)

^d SANOFI PASTEUR   (France)

^e UNIVERSITY OF TURKU   (Finland)

^f UNIVERSITY OF TURKU   (Finland)

^g TURKU UNIVERSITY HOSPITAL   (Finland)

^h OULU UNIVERSITY HOSPITAL   (Finland)

ⁱ TAMPERE UNIVERSITY HOSPITAL   (Finland)

^j UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^k UNIVERSITY OF HELSINKI   (Finland)

^l FOLKHÄLSAN RESEARCH CENTER   (Finland)

more..

Author keywords

Enterovirus; Genotyping; RT PCR; Stool samples; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; HLA DQ ANTIGEN; HLA DR ANTIGEN; VIRUS RNA;

ANTIBODY DETECTION; ARTICLE; AUTOIMMUNITY; CASE CONTROL STUDY; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; COXSACKIEVIRUS A16; COXSACKIEVIRUS A2; COXSACKIEVIRUS A4; ENTEROVIRUS; ENTEROVIRUS INFECTION; FECES; FEMALE; FINLAND; GENE SEQUENCE; GENOTYPE; HUMAN; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NEWBORN; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROCONVERSION; VIRUS DETECTION; GENETICS; IMMUNOLOGY; PATHOGENICITY; PRESCHOOL CHILD; PROSPECTIVE STUDY; VIROLOGY;

AUTOIMMUNITY; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; ENTEROVIRUS; FECES; FEMALE; GENOTYPE; HUMANS; INFANT; ISLETS OF LANGERHANS; MALE; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 85008674656     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-4177-z     Document Type: Article

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