-
1
-
-
0026062620
-
Gram-negative endotoxin: An extraordinary lipid with profound effects on eukaryotic signal transduction
-
Raetz, C. R. et al. Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction. Faseb J 5, 2652-2660 (1991).
-
(1991)
Faseb J
, vol.5
, pp. 2652-2660
-
-
Raetz, C.R.1
-
2
-
-
0035997382
-
Lipopolysaccharide endotoxins
-
Raetz, C. R. & Whitfield, C. Lipopolysaccharide endotoxins. Annu Rev Biochem 71, 635-700, doi: 10.1146/annurev. biochem.71.110601.135414 (2002).
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 635-700
-
-
Raetz, C.R.1
Whitfield, C.2
-
3
-
-
0036069961
-
Structural and functional analyses of bacterial lipopolysaccharides
-
Caroff, M., Karibian, D., Cavaillon, J. M. & Haeffner-Cavaillon, N. Structural and functional analyses of bacterial lipopolysaccharides. Microbes Infect 4, 915-926 (2002).
-
(2002)
Microbes Infect
, vol.4
, pp. 915-926
-
-
Caroff, M.1
Karibian, D.2
Cavaillon, J.M.3
Haeffner-Cavaillon, N.4
-
4
-
-
84888104327
-
The immunobiology of toll-like receptor, 4 agonists: From endotoxin tolerance to immunoadjuvants
-
Bohannon, J. K., Hernandez, A., Enkhbaatar, P., Adams, W. L. & Sherwood, E. R. The immunobiology of toll-like receptor, 4 agonists: from endotoxin tolerance to immunoadjuvants. Shock 40, 451-462, doi: 10.1097/SHK.0000000000000042 (2013).
-
(2013)
Shock
, vol.40
, pp. 451-462
-
-
Bohannon, J.K.1
Hernandez, A.2
Enkhbaatar, P.3
Adams, W.L.4
Sherwood, E.R.5
-
5
-
-
84862850350
-
Understanding efflux in Gram-negative bacteria: Opportunities for drug discovery
-
Schweizer, H. P. Understanding efflux in Gram-negative bacteria: opportunities for drug discovery. Expert opinion on drug discovery 7, 633-642, doi: 10.1517/17460441.2012.688949 (2012).
-
(2012)
Expert Opinion on Drug Discovery
, vol.7
, pp. 633-642
-
-
Schweizer, H.P.1
-
6
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 (1998).
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
-
7
-
-
0035115080
-
Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
-
Hirschfeld, M. et al. Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect Immun 69, 1477-1482, doi: 10.1128/IAI.69.3.1477-1482.2001 (2001).
-
(2001)
Infect Immun
, vol.69
, pp. 1477-1482
-
-
Hirschfeld, M.1
-
8
-
-
77952525214
-
Lipid A receptor TLR4-mediated signaling pathways
-
Yamamoto, M. & Akira, S. Lipid A receptor TLR4-mediated signaling pathways. Adv Exp Med Biol 667, 59-68 (2009).
-
(2009)
Adv Exp Med Biol
, vol.667
, pp. 59-68
-
-
Yamamoto, M.1
Akira, S.2
-
9
-
-
84922101673
-
Co-operation of TLR4 and raft proteins in LPSinduced pro-inflammatory signaling
-
Plociennikowska, A., Hromada-Judycka, A., Borzecka, K. & Kwiatkowska, K. Co-operation of TLR4 and raft proteins in LPSinduced pro-inflammatory signaling. Cellular and molecular life sciences: CMLS 72, 557-581, doi: 10.1007/s00018-014-1762-5 (2015).
-
(2015)
Cellular and Molecular Life Sciences: CMLS
, vol.72
, pp. 557-581
-
-
Plociennikowska, A.1
Hromada-Judycka, A.2
Borzecka, K.3
Kwiatkowska, K.4
-
10
-
-
84959273475
-
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
-
Singer, M. et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Jama 315, 801-810, doi: 10.1001/jama.2016.0287 (2016).
-
(2016)
Jama
, vol.315
, pp. 801-810
-
-
Singer, M.1
-
11
-
-
0035158914
-
Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar typhimurium infection despite attenuated cytokine response
-
Lehner, M. D. et al. Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar typhimurium infection despite attenuated cytokine response. Infection and immunity 69, 463-471, doi: 10.1128/IAI.69.1.463-471.2001 (2001).
-
(2001)
Infection and Immunity
, vol.69
, pp. 463-471
-
-
Lehner, M.D.1
-
12
-
-
40949114220
-
Endotoxin pretreatment improves bacterial clearance and decreases mortality in mice challenged with Staphylococcus aureus
-
Murphey, E. D., Fang, G. & Sherwood, E. R. Endotoxin pretreatment improves bacterial clearance and decreases mortality in mice challenged with Staphylococcus aureus. Shock 29, 512-518, doi: 10.1097/shk.0b013e318150776f (2008).
-
(2008)
Shock
, vol.29
, pp. 512-518
-
-
Murphey, E.D.1
Fang, G.2
Sherwood, E.R.3
-
13
-
-
2342430991
-
Molecular mechanisms of endotoxin tolerance
-
Fan, H. & Cook, J. A. Molecular mechanisms of endotoxin tolerance. J Endotoxin Res 10, 71-84, doi: 10.1179/096805104225003997 (2004).
-
(2004)
J Endotoxin Res
, vol.10
, pp. 71-84
-
-
Fan, H.1
Cook, J.A.2
-
14
-
-
33847036222
-
Improved bacterial clearance and decreased mortality can be induced by LPS tolerance and is not dependent upon IFN-gamma
-
Murphey, E. D., Fang, G., Varma, T. K. & Sherwood, E. R. Improved bacterial clearance and decreased mortality can be induced by LPS tolerance and is not dependent upon IFN-gamma. Shock 27, 289-295, doi: 10.1097/01.shk.0000245024.93740.28 (2007).
-
(2007)
Shock
, vol.27
, pp. 289-295
-
-
Murphey, E.D.1
Fang, G.2
Varma, T.K.3
Sherwood, E.R.4
-
15
-
-
0023402959
-
Characterization of a nontoxic monophosphoryl lipid A
-
Johnson, A. G., Tomai, M., Solem, L., Beck, L. & Ribi, E. Characterization of a nontoxic monophosphoryl lipid A. Rev Infect Dis 9 Suppl 5, S512-516 (1987).
-
(1987)
Rev Infect Dis
, vol.9
, pp. S512-S516
-
-
Johnson, A.G.1
Tomai, M.2
Solem, L.3
Beck, L.4
Ribi, E.5
-
16
-
-
84862659753
-
Adjuvants for human vaccines
-
Alving, C. R., Peachman, K. K., Rao, M. & Reed, S. G. Adjuvants for human vaccines. Current opinion in immunology 24, 310-315, doi: 10.1016/j.coi.2012.03.008 (2012).
-
(2012)
Current Opinion in Immunology
, vol.24
, pp. 310-315
-
-
Alving, C.R.1
Peachman, K.K.2
Rao, M.3
Reed, S.G.4
-
17
-
-
0028525990
-
Monophosphoryl lipid A protects against gram-positive sepsis and tumor necrosis factor
-
Astiz, M. E., Galera, A., Saha, D. C., Carpati, C. & Rackow, E. C. Monophosphoryl lipid A protects against gram-positive sepsis and tumor necrosis factor. Shock 2, 271-274 (1994).
-
(1994)
Shock
, vol.2
, pp. 271-274
-
-
Astiz, M.E.1
Galera, A.2
Saha, D.C.3
Carpati, C.4
Rackow, E.C.5
-
18
-
-
0026092964
-
Monophosphoryl lipid A induces tolerance to the lethal hemodynamic effects of endotoxemia
-
Astiz, M. E., Rackow, E. C., Kim, Y. B. & Weil, M. H. Monophosphoryl lipid A induces tolerance to the lethal hemodynamic effects of endotoxemia. Circulatory shock 33, 92-97 (1991).
-
(1991)
Circulatory Shock
, vol.33
, pp. 92-97
-
-
Astiz, M.E.1
Rackow, E.C.2
Kim, Y.B.3
Weil, M.H.4
-
19
-
-
80052305941
-
The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection
-
Romero, C. D. et al. The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infect Immun 79, 3576-3587, doi: 10.1128/IAI.00022-11 (2011).
-
(2011)
Infect Immun
, vol.79
, pp. 3576-3587
-
-
Romero, C.D.1
-
20
-
-
84962377303
-
Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury
-
Bohannon, J. K. et al. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. Journal of leukocyte biology 99, 629-640, doi: 10.1189/jlb.4A0815-362R (2016).
-
(2016)
Journal of Leukocyte Biology
, vol.99
, pp. 629-640
-
-
Bohannon, J.K.1
-
21
-
-
85002909118
-
The role of MyD88-and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes
-
Hernandez, A. et al. The role of MyD88-and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. Journal of leukocyte biology, doi: 10.1189/jlb.1A0216-072R (2016).
-
(2016)
Journal of Leukocyte Biology
-
-
Hernandez, A.1
-
22
-
-
84942371618
-
MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS
-
Schulke, S. et al. MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS. Allergy 70, 1259-1268, doi: 10.1111/all.12675 (2015).
-
(2015)
Allergy
, vol.70
, pp. 1259-1268
-
-
Schulke, S.1
-
23
-
-
84975267577
-
A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses in Vitro
-
Schulke, S. et al. A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro. J Immunol Res 2016, 4156456, doi: 10.1155/2016/4156456 (2016).
-
(2016)
J Immunol Res
, vol.2016
-
-
Schulke, S.1
-
24
-
-
84873725252
-
Effects of Differences in Lipid A Structure on TLR4 Pro-Inflammatory Signaling and Inflammasome Activation
-
Chilton, P. M., Embry, C. A. & Mitchell, T. C. Effects of Differences in Lipid A Structure on TLR4 Pro-Inflammatory Signaling and Inflammasome Activation. Front Immunol 3, 154, doi: 10.3389/fimmu.2012.00154 (2012).
-
(2012)
Front Immunol
, vol.3
, pp. 154
-
-
Chilton, P.M.1
Embry, C.A.2
Mitchell, T.C.3
-
25
-
-
79955681975
-
Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A
-
Embry, C. A., Franchi, L., Nunez, G. & Mitchell, T. C. Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A. Sci Signal 4, ra28, doi: 10.1126/scisignal.2001486 (2011).
-
(2011)
Sci Signal
, vol.4
, pp. ra28
-
-
Embry, C.A.1
Franchi, L.2
Nunez, G.3
Mitchell, T.C.4
-
26
-
-
84893525976
-
Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock
-
Vanden Berghe, T. et al. Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock. Am J Respir Crit Care Med 189, 282-291, doi: 10.1164/rccm.201308-1535OC (2014).
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 282-291
-
-
Vanden Berghe, T.1
-
27
-
-
27744598776
-
Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice
-
Varma, T. K. et al. Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice. Infect Immun 73, 7340-7347, doi: 10.1128/IAI.73.11.7340-7347.2005 (2005).
-
(2005)
Infect Immun
, vol.73
, pp. 7340-7347
-
-
Varma, T.K.1
-
28
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
Mata-Haro, V. et al. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 316, 1628-1632, doi: 10.1126/science.1138963 (2007).
-
(2007)
Science
, vol.316
, pp. 1628-1632
-
-
Mata-Haro, V.1
-
29
-
-
0028813843
-
Pretreatment of normal humans with monophosphoryl lipid A induces tolerance to endotoxin: A prospective, double-blind, randomized, controlled trial
-
Astiz, M. E. et al. Pretreatment of normal humans with monophosphoryl lipid A induces tolerance to endotoxin: a prospective, double-blind, randomized, controlled trial. Crit Care Med 23, 9-17 (1995).
-
(1995)
Crit Care Med
, vol.23
, pp. 9-17
-
-
Astiz, M.E.1
-
30
-
-
70349559403
-
Endotoxin tolerance: New mechanisms, molecules and clinical significance
-
Biswas, S. K. & Lopez-Collazo, E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol 30, 475-487, doi: 10.1016/j.it.2009.07.009 (2009).
-
(2009)
Trends Immunol
, vol.30
, pp. 475-487
-
-
Biswas, S.K.1
Lopez-Collazo, E.2
-
31
-
-
57349111274
-
AS04-adjuvanted human papillomavirus-16/18 vaccination: Recent advances in cervical cancer prevention
-
Schwarz, T. F. AS04-adjuvanted human papillomavirus-16/18 vaccination: recent advances in cervical cancer prevention. Expert Rev Vaccines 7, 1465-1473, doi: 10.1586/14760584.7.10.1465 (2008).
-
(2008)
Expert Rev Vaccines
, vol.7
, pp. 1465-1473
-
-
Schwarz, T.F.1
-
32
-
-
77949500672
-
Cervarix: A vaccine for the prevention of HPV 16, 18-associated cervical cancer
-
Monie, A., Hung, C. F., Roden, R. & Wu, T. C. Cervarix: a vaccine for the prevention of HPV 16, 18-associated cervical cancer. Biologics 2, 97-105 (2008).
-
(2008)
Biologics
, vol.2
, pp. 97-105
-
-
Monie, A.1
Hung, C.F.2
Roden, R.3
Wu, T.C.4
-
33
-
-
77957045079
-
Lipopolysaccharide-induced expression of cell surface receptors and cell activation of neutrophils and monocytes in whole human blood
-
Gomes, N. E. et al. Lipopolysaccharide-induced expression of cell surface receptors and cell activation of neutrophils and monocytes in whole human blood. Braz J Med Biol Res 43, 853-858 (2010).
-
(2010)
Braz J Med Biol Res
, vol.43
, pp. 853-858
-
-
Gomes, N.E.1
-
34
-
-
0036569658
-
Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: A critical role for monocytes in leukocyte lipopolysaccharide responses
-
Sabroe, I., Jones, E. C., Usher, L. R., Whyte, M. K. & Dower, S. K. Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. Journal of immunology 168, 4701-4710 (2002).
-
(2002)
Journal of Immunology
, vol.168
, pp. 4701-4710
-
-
Sabroe, I.1
Jones, E.C.2
Usher, L.R.3
Whyte, M.K.4
Dower, S.K.5
-
35
-
-
80052305941
-
The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection
-
Romero, C. D. et al. The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infection and immunity 79, 3576-3587, doi: 10.1128/IAI.00022-11 (2011).
-
(2011)
Infection and Immunity
, vol.79
, pp. 3576-3587
-
-
Romero, C.D.1
|