Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review

Clinics in Perinatology

Volumn 44, Issue 1, 2017, Pages 49-67

  Cacho, Nicole Theresa ^a   Parker, Leslie A ^b   Neu, Josef ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Donor milk; Exclusive human milk; Human milk; Necrotizing enterocolitis; Premature infant

Indexed keywords

BIRTH WEIGHT; BREAST MILK; CHILD GROWTH; DIETARY INTAKE; GESTATIONAL AGE; HUMAN; INCIDENCE; INFANT FEEDING; META ANALYSIS (TOPIC); NECROTIZING ENTEROCOLITIS; OBSERVATIONAL STUDY; PREMATURITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); RETROSPECTIVE STUDY; REVIEW; RISK REDUCTION; WEIGHT GAIN; BREAST FEEDING; BREAST MILK EXPRESSION; NEWBORN; PROTECTION; STATISTICS AND NUMERICAL DATA; TRANSPLANTATION;

BREAST FEEDING; BREAST MILK EXPRESSION; ENTEROCOLITIS, NECROTIZING; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MILK, HUMAN; PROTECTIVE FACTORS; TISSUE AND ORGAN PROCUREMENT;

EID: 85008190245     PISSN: 00955108     EISSN: 15579840     Source Type: Journal    
DOI: 10.1016/j.clp.2016.11.009     Document Type: Review

References (67)

1. 1 Section on Breastfeeding, Breastfeeding and the use of human milk. Pediatrics 129:3 (2012), e827–e841.
2. 2 Patel, A.L., Johnson, T.J., Engstrom, J.L., et al. Impact of early human milk on sepsis and health-care costs in very low birth weight infants. J Perinatol 33:7 (2013), 514–519.
3. 3 Bharwani, S.K., Green, B.F., Pezzullo, J.C., et al. Systematic review and meta-analysis of human milk intake and retinopathy of prematurity: a significant update. J Perinatol 36:11 (2016), 913–920.
4. 4 Vohr, B.R., Poindexter, B.B., Dusick, A.M., et al. Beneficial effects of breast milk in the neonatal intensive care unit on the developmental outcome of extremely low birth weight infants at 18 months of age. Pediatrics 118:1 (2006), e115–e123.
5. 5 Isaacs, E.B., Fischl, B.R., Quinn, B.T., et al. Impact of breast milk on intelligence quotient, brain size, and white matter development. Pediatr Res 67:4 (2010), 357–362.
6. 6 Singhal, A., Cole, T.J., Fewtrell, M., et al. Breastmilk feeding and lipoprotein profile in adolescents born preterm: follow-up of a prospective randomised study. Lancet 363:9421 (2004), 1571–1578.
7. 7 Singhal, A., Cole, T.J., Lucas, A., Early nutrition in preterm infants and later blood pressure: two cohorts after randomised trials. Lancet 357:9254 (2001), 413–419.
8. 8 Sullivan, S., Schanler, R.J., Kim, J.H., et al. An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk-based products. J Pediatr 156:4 (2010), 562–567.e1.
9. 9 Schanler, R.J., Lau, C., Hurst, N.M., et al. Randomized trial of donor human milk versus preterm formula as substitutes for mothers’ own milk in the feeding of extremely premature infants. Pediatrics 116:2 (2005), 400–406.
10. 10 Neu, J., Walker, W.A., Necrotizing enterocolitis. N Engl J Med 364:3 (2011), 255–264.
11. 11 Horbar, J.D., Carpenter, J.H., Badger, G.J., et al. Mortality and neonatal morbidity among infants 501 to 1500 grams from 2000 to 2009. Pediatrics 129:6 (2012), 1019–1026.
12. 12 Picciolini, O., Montirosso, R., Porro, M., et al. Neurofunctional assessment at term equivalent age can predict 3-year neurodevelopmental outcomes in very low birth weight infants. Acta Paediatr 105:2 (2016), e47–e53.
13. 13 Parker, M.G., Barrero-Castillero, A., Corwin, B.K., et al. Pasteurized human donor milk use among US level 3 neonatal intensive care units. J Hum Lact 29:3 (2013), 381–389.
14. 14 Hagadorn, J.I., Brownell, E.A., Lussier, M.M., et al. Variability of criteria for pasteurized donor human milk use: a survey of U.S. Neonatal Intensive Care Unit Medical Directors. JPEN J Parenter Enteral Nutr 40:3 (2016), 326–333.
15. 15 Oxford Centre for Evidence-Based Medicine—levels of evidence 2009. Available at: http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march- 2009. Accessed May 4, 2016.
16. 16 Boyd, C.A., Quigley, M.A., Brocklehurst, P., Donor breast milk versus infant formula for preterm infants: systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed 92:3 (2007), F169–F175.
17. 17 Quigley, M., McGuire, W., Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev, 4, 2014 CD002971.
18. 18 Corpeleijn, W.E., de Waard, M., Christmann, V., et al. Effect of donor milk on severe infections and mortality in very low-birth-weight infants: the Early Nutrition Study randomized clinical trial. JAMA Pediatr 170:7 (2016), 654–661.
19. 19 Kantorowska, A., Wei, J.C., Cohen, R.S., et al. Impact of donor milk availability on breast milk use and necrotizing enterocolitis rates. Pediatrics, 137(3), 2016, e20153123.
20. 20 Chowning, R., Radmacher, P., Lewis, S., et al. A retrospective analysis of the effect of human milk on prevention of necrotizing enterocolitis and postnatal growth. J Perinatol 36:3 (2016), 221–224.
21. 21 Abrams, S.A., Schanler, R.J., Lee, M.L., et al. Greater mortality and morbidity in extremely preterm infants fed a diet containing cow milk protein products. Breastfeed Med 9:6 (2014), 281–285.
22. 22 Cristofalo, E.A., Schanler, R.J., Blanco, C.L., et al. Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants. J Pediatr 163:6 (2013), 1592–1595.e1.
23. 23 Herrmann, K., Carroll, K., An exclusively human milk diet reduces necrotizing enterocolitis. Breastfeed Med 9:4 (2014), 184–190.
24. 24 Hair, A.B., Peluso, A.M., Hawthorne, K.M., et al. Beyond necrotizing enterocolitis prevention: improving outcomes with an exclusive human milk-based diet. Breastfeed Med 11:2 (2016), 70–74.
25. 25 Assad, M., Elliott, M.J., Abraham, J.H., Decreased cost and improved feeding tolerance in VLBW infants fed an exclusive human milk diet. J Perinatol 36:3 (2016), 216–220.
26. 26 Meinzen-Derr, J., Poindexter, B., Wrage, L., et al. Role of human milk in extremely low birth weight infants’ risk of necrotizing enterocolitis or death. J Perinatol 29:1 (2009), 57–62.
27. 27 Corpeleijn, W.E., Kouwenhoven, S.M., Paap, M.C., et al. Intake of own mother's milk during the first days of life is associated with decreased morbidity and mortality in very low birth weight infants during the first 60 days of life. Neonatology 102:4 (2012), 276–281.
28. 28 Furman, L., Taylor, G., Minich, N., et al. The effect of maternal milk on neonatal morbidity of very low-birth-weight infants. Arch Pediatr Adolesc Med 157:1 (2003), 66–71.
29. 29 Kimak, K.S., de Castro Antunes, M.M., Braga, T.D., et al. Influence of enteral nutrition on occurrences of necrotizing enterocolitis in very-low- birth-weight infants. J Pediatr Gastroenterol Nutr 61:4 (2015), 445–450.
30. 30 Montjaux-Regis, N., Cristini, C., Arnaud, C., et al. Improved growth of preterm infants receiving mother's own raw milk compared with pasteurized donor milk. Acta Paediatr 100:12 (2011), 1548–1554.
31. 31 Maayan-Metzger, A., Avivi, S., Schushan-Eisen, I., et al. Human milk versus formula feeding among preterm infants: short-term outcomes. Am J Perinatol 29:2 (2012), 121–126.
32. 32 Stout, G., Lambert, D.K., Baer, V.L., et al. Necrotizing enterocolitis during the first week of life: a multicentered case-control and cohort comparison study. J Perinatol 28:8 (2008), 556–560.
33. 33 Lin, P.W., Stoll, B.J., Necrotising enterocolitis. Lancet 368:9543 (2006), 1271–1283.
34. 34 Yee, W.H., Soraisham, A.S., Shah, V.S., et al. Incidence and timing of presentation of necrotizing enterocolitis in preterm infants. Pediatrics 129:2 (2012), e298–e304.
35. 35 Grave, G.D., Nelson, S.A., Walker, W.A., et al. New therapies and preventive approaches for necrotizing enterocolitis: report of a research planning workshop. Pediatr Res 62:4 (2007), 510–514.
36. 36 Gordon, P.V., The little database that could: Intermountain Health Care and the uphill quest for prevention of term necrotizing enterocolitis. J Perinatol 27:7 (2007), 397–398.
37. 37 Pickard, S.S., Feinstein, J.A., Popat, R.A., et al. Short- and long-term outcomes of necrotizing enterocolitis in infants with congenital heart disease. Pediatrics 123:5 (2009), e901–e906.
38. 38 Arslanoglu, S., Corpeleijn, W., Moro, G., et al. Donor human milk for preterm infants: current evidence and research directions. J Pediatr Gastroenterol Nutr 57:4 (2013), 535–542.
39. 39 Guidelines on optimal feeding of low birth-weight infants in low- and middle-income countries, 2011, World Health Organization, Geneva (Switzerland).
40. 40 Parker, L.A., Sullivan, S., Krueger, C., et al. Effect of early breast milk expression on milk volume and timing of lactogenesis stage II among mothers of very low birth weight infants: a pilot study. J Perinatol 32:3 (2012), 205–209.
41. 41 Mai, V., Young, C.M., Ukhanova, M., et al. Fecal microbiota in premature infants prior to necrotizing enterocolitis. PLoS One, 6(6), 2011, e20647.
42. 42 Rogier, E.W., Frantz, A.L., Bruno, M.E., et al. Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression. Proc Natl Acad Sci U S A 111:8 (2014), 3074–3079.
43. 43 Neu, J., Mihatsch, W.A., Zegarra, J., et al. Intestinal mucosal defense system, Part 1. Consensus recommendations for immunonutrients. J Pediatr 162:3 Suppl (2013), S56–S63.
44. 44 Hunt, K.M., Foster, J.A., Forney, L.J., et al. Characterization of the diversity and temporal stability of bacterial communities in human milk. PLoS One, 6(6), 2011, e21313.
45. 45 Ewaschuk, J.B., Unger, S., O'Connor, D.L., et al. Effect of pasteurization on selected immune components of donated human breast milk. J Perinatol 31:9 (2011), 593–598.
46. 46 Peila, C., Moro, G.E., Bertino, E., et al. The effect of holder pasteurization on nutrients and biologically-active components in donor human milk: a review. Nutrients, 8(8), 2016 [pii:E477].
47. 47 Mehta, R., Petrova, A., Biologically active breast milk proteins in association with very preterm delivery and stage of lactation. J Perinatol 31:1 (2011), 58–62.
48. 48 Castellote, C., Casillas, R., Ramirez-Santana, C., et al. Premature delivery influences the immunological composition of colostrum and transitional and mature human milk. J Nutr 141:6 (2011), 1181–1187.
49. 49 Hassiotou, F., Hepworth, A.R., Metzger, P., et al. Maternal and infant infections stimulate a rapid leukocyte response in breastmilk. Clin Transl Immunology, 2(4), 2013, e3.
50. 50 Ehrenkranz, R.A., Dusick, A.M., Vohr, B.R., et al. Growth in the neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants. Pediatrics 117:4 (2006), 1253–1261.
51. 51 Dritsakou, K., Liosis, G., Valsami, G., et al. Improved outcomes of feeding low birth weight infants with predominantly raw human milk versus donor banked milk and formula. J Matern Fetal Neonatal Med 29:7 (2016), 1131–1138.
52. 52 Colaizy, T.T., Carlson, S., Saftlas, A.F., et al. Growth in VLBW infants fed predominantly fortified maternal and donor human milk diets: a retrospective cohort study. BMC Pediatr, 12, 2012, 124.
53. 53 Koivusalo, A., Kauppinen, H., Anttila, A., et al. Intraluminal casein model of necrotizing enterocolitis for assessment of mucosal destruction, bacterial translocation, and the effects of allopurinol and N-acetylcysteine. Pediatr Surg Int 18:8 (2002), 712–717.
54. 54 Friel, J.K., Diehl-Jones, B., Cockell, K.A., et al. Evidence of oxidative stress in relation to feeding type during early life in premature infants. Pediatr Res 69:2 (2011), 160–164.
55. 55 Brown, J.V., Embleton, N.D., Harding, J.E., et al. Multi-nutrient fortification of human milk for preterm infants. Cochrane Database Syst Rev(5), 2016 CD000343.
56. 56 Shah, S.D., Dereddy, N., Jones, T.L., et al. Early secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression. J Pediatr 174 (2016), 126–131.e1.
57. 57 Tillman, S., Brandon, D.H., Silva, S.G., Evaluation of human milk fortification from the time of the first feeding: effects on infants of less than 31 weeks gestational age. J Perinatol 32:7 (2012), 525–531.
58. 58 Sisk, P.M., Lovelady, C.A., Dillard, R.G., et al. Early human milk feeding is associated with a lower risk of necrotizing enterocolitis in very low birth weight infants. J Perinatol 27:7 (2007), 428–433.
59. 59 Patel, A., Engstrom, J., Goldman, J., et al. Dose response benefits of human milk in extremely low birth weight premature infants [abstract]. Pediatric Academic Socities, 2008.
60. 60 Vohr, B.R., Poindexter, B.B., Dusick, A.M., et al. Persistent beneficial effects of breast milk ingested in the neonatal intensive care unit on outcomes of extremely low birth weight infants at 30 months of age. Pediatrics 120:4 (2007), e953–e959.
61. 61 Meier, P.P., Engstrom, J.L., Patel, A.L., et al. Improving the use of human milk during and after the NICU stay. Clin Perinatol 37:1 (2010), 217–245.
62. 62 Bisquera, J.A., Cooper, T.R., Berseth, C.L., Impact of necrotizing enterocolitis on length of stay and hospital charges in very low birth weight infants. Pediatrics 109:3 (2002), 423–428.
63. 63 Johnson, T.J., Patel, A.L., Bigger, H.R., et al. Cost savings of human milk as a strategy to reduce the incidence of necrotizing enterocolitis in very low birth weight infants. Neonatology 107:4 (2015), 271–276.
64. 64 Colaizy, T.T., Bartick, M.C., Jegier, B.J., et al. Impact of optimized breastfeeding on the costs of necrotizing enterocolitis in extremely low birthweight infants. J Pediatr 175 (2016), 100–105.e2.
65. 65 Carroll, K., Herrmann, K.R., The cost of using donor human milk in the NICU to achieve exclusively human milk feeding through 32 weeks postmenstrual age. Breastfeed Med 8:3 (2013), 286–290.
66. 66 Oza-Frank, R., Bhatia, A., Smith, C., Combined peer counselor and lactation consultant support increases breastfeeding in the NICU. Breastfeed Med 8:6 (2013), 509–510.
67. 67 Meier, P.P., Engstrom, J.L., Rossman, B., Breastfeeding peer counselors as direct lactation care providers in the neonatal intensive care unit. J Hum Lact 29:3 (2013), 313–322.