Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants

Journal of Pediatrics

Volumn 175, Issue , 2016, Pages 100-105.e2

  Colaizy, Tarah T ^a,k   Bartick, Melissa C ^b   Jegier, Briana J ^c   Green, Brittany D ^d   Reinhold, Arnold G ^e   Schaefer, Andrew J ^f   Bogen, Debra L ^g   Schwarz, Eleanor Bimla ^h   Stuebe, Alison M ^i,j   Jobe, Alan H ^k   Oh, William ^k   Vohr, Betty R ^k   Walden, Rachel V ^k   Alksninis, Barbara ^k   Hensman, Angelita M ^k   Leonard, Martha R ^k   Noel, Lucy ^k   Leach, Teresa M ^k   Watson, Victoria E ^k   Fanaroff, Avroy A ^k   Walsh, Michele C ^k   Wilson Costello, Deanne E ^k   Newman, Nancy S ^k   Siner, Bonnie S ^k   Friedman, Harriet G ^k   Donovan, Edward F ^k   Schibler, Kurt ^k   Steichen, Jean J ^k   Alexander, Barbara ^k   Grisby, Cathy ^k   Mersmann, Marcia Worley ^k   Mincey, Holly L ^k   Hessling, Jody ^k   Gratton, Teresa L ^k   Stoll, Barbara J ^k   Adams Chapman, Ira ^k   Hale, Ellen C ^k   LaRossa, Maureen Mulligan ^k   Carter, Sheena ^k   Higgins, Rosemary D ^k   Wright, Linda L ^k   McClure, Elizabeth M ^k   Poindexter, Brenda B ^k   Lemons, James A ^k   Dusick, Anna M ^k   Kardatzke, Darlene ^k   Lytle, Carolyn ^k   Appel, Diana D ^k   Bohnke, Lon G ^k   Eaken, Greg ^k   Herron, Dianne E ^k   Miller, Lucy C ^k   Richard, Leslie ^k   Wilson, Leslie Dawn ^k   Das, Abhik ^k   Poole, W Kenneth ^k   Wrage, Lisa Ann ^k   Hastings, Betty K ^k   O'Donnell Auman, Jeanette ^k   Taylor, Sarah ^k   Stevenson, David K ^k   Hintz, Susan R ^k   Ball, M Bethany ^k   Kohn, Jean G ^k   Baran, Joan M ^k   Lee Ancajas, Julie C ^k   St John, Nicholas H ^k   Carlo, Waldemar A ^k   Ambalavanan, Namasivayam ^k   Nelson, Kathleen G ^k   Peralta Carcelen, Myriam ^k   Bailey, Kirstin J ^k   Biasini, Fred J ^k   Chopko, Stephanie A ^k   Collins, Monica V ^k   Cosby, Shirley S ^k   Phillips, Vivien A ^k   Rector, Richard V ^k   Finer, Neil N ^k   Vaucher, Yvonne E ^k   Anderson, Jack M ^k   Rasmussen, Maynard R ^k   Arnell, Kathy ^k   Demetrio, Clarence ^k   Fuller, Martha G ^k   Henderson, Christopher ^k   Posin, Donna ^k   Bell, Edward F ^k   Bauer, Charles R ^k   Duara, Shahnaz ^k   Worth, Amy Mur ^k   Everett Thomas, Ruth ^k   Diaz, Alexis N ^k   Mathews, Elaine O ^k   Hamlin Smith, Kasey ^k   Jean Gilles, Lisa ^k   Calejo, Maria ^k   Frade, Silvia M ^k   Hiriart Fajardo, Silvia ^k   Gideon, Yamiley ^k   Korones, Sheldon B ^k   Bada, Henrietta S ^k   Hudson, Tina ^k   Yolton, Kimberly ^k   Williams, Marilyn G ^k   Laptook, Abbot R ^k   Salhab, Walid A ^k   Broyles, R Sue ^k   Madison, Susie ^k   Hickman, Jackie F ^k   Guzman, Alicia ^k   Adams, Sally S ^k   Madden, Linda A ^k   Heyne, Elizabeth T ^k   Dooley, Cristin ^k   Shankaran, Seetha ^k   Delaney Black, Virginia ^k   Johnson, Yvette R ^k   Bara, Rebecca ^k   Muran, Geraldine ^k   Kennedy, Deborah ^k   Goldston, Laura A ^k   Ehrenkranz, Richard A ^k   Gettner, Patricia ^k   Konstantino, Monica ^k   Romano, Elaine ^k   Close, Nancy ^k   Gilliam, Walter S ^k   Poulsen, JoAnn ^k   more..

^a UNIVERSITY OF IOWA   (United States)

^b CAMBRIDGE HEALTH ALLIANCE   (United States)

^c D'YOUVILLE COLLEGE   (United States)

^d University of Pittsburgh   (United States)

^e Alliance for the Prudent Use of Antibiotics   (United States)

^f Rice University   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^j University of North Carolina at Chapel Hill   (United States)

^k NONE

more..

Author keywords

economic analysis; human milk; monte carlo modeling; necrotizing enterocolitis

Indexed keywords

ARTICLE; ARTIFICIAL MILK; BREAST FEEDING; BREAST MILK; CONTROLLED STUDY; EXTREMELY LOW BIRTH WEIGHT; GESTATIONAL AGE; HEALTH CARE COST; HUMAN; INCIDENCE; INFANT; INFANT FEEDING; MAJOR CLINICAL STUDY; MONTE CARLO METHOD; NECROTIZING ENTEROCOLITIS; PREMATURITY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK REDUCTION; ECONOMIC MODEL; ECONOMICS; ENTEROCOLITIS, NECROTIZING; INFANT, PREMATURE, DISEASES; NEWBORN; STATISTICS AND NUMERICAL DATA; UNITED STATES;

BREAST FEEDING; ENTEROCOLITIS, NECROTIZING; HEALTH CARE COSTS; HUMANS; INFANT FORMULA; INFANT, EXTREMELY LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MILK, HUMAN; MODELS, ECONOMIC; MONTE CARLO METHOD; UNITED STATES;

EID: 84964669478     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2016.03.040     Document Type: Article

References (44)

1. 1 Schanler, R.J., Shulman, R.J., Lau, C., Feeding strategies for premature infants: beneficial outcomes of feeding fortified human milk versus preterm formula. Pediatrics 103:6 Pt 1 (1999), 1150–1157.
2. 2 Schanler, R.J., Lau, C., Hurst, N.M., Smith, E.O.B., Randomized trial of donor human milk versus preterm formula as substitutes for mothers’ own milk in the feeding of extremely premature infants. Pediatrics 116 (2005), 400–406.
3. 3 Lucas, A., Cole, T.J., Breast milk and neonatal necrotizing enterocolitis. [see comment] Lancet 336 (1990), 1519–1523.
4. 4 Maayan-Metzger, A., Avivi, S., Schushan-Eisen, I., Kuint, J., Human milk versus formula feeding among preterm infants: short-term outcomes. Am J Perinatol 29 (2011), 121–126.
5. 5 Sisk, P.M., Lovelady, C.A., Dillard, R.G., Gruber, K.J., O'Shea, T.M., Early human milk feeding is associated with a lower risk of necrotizing enterocolitis in very low birth weight infants. J Perinatol 27 (2007), 428–433.
6. 6 Meinzen-Derr, J., Poindexter, B., Wrage, L., Morrow, A.L., Stoll, B., Donovan, E.F., Role of human milk in extremely low birth weight infants’ risk of necrotizing enterocolitis or death. J Perinatol 29 (2009), 57–62.
7. 7 Vohr, B.R., Poindexter, B.B., Dusick, A.M., McKinley, L.T., Wright, L.L., Langer, J.C., et al. Beneficial effects of breast milk in the neonatal intensive care unit on the developmental outcome of extremely low birth weight infants at 18 months of age. Pediatrics 118 (2006), e115–e123.
8. 8 Jegier, B.J., Johnson, T.J., Engstrom, J.L., Patel, A.L., Loera, F., Meier, P., The institutional cost of acquiring 100 mL of human milk for very low birth weight infants in the neonatal intensive care unit. J Hum Lact 29 (2013), 390–399.
9. 9 Colaizy, T.T., Morriss, F.H., Positive effect of NICU admission on breastfeeding of preterm US infants in 2000 to 2003. J Perinatol 28 (2008), 505–510.
10. 10 Bigger, H.R., Fogg, L.J., Patel, A., Johnson, T., Engstrom, J.L., Meier, P.P., Quality indicators for human milk use in very low-birthweight infants: are we measuring what we should be measuring?. J Perinatol 34 (2014), 287–291.
11. 11 Bartick, M., Reinhold, A., The burden of suboptimal breastfeeding in the United States: a pediatric cost analysis. Pediatrics 125 (2010), e1048–e1056.
12. 12 Bartick, M.C., Stuebe, A.M., Schwarz, E.B., Luongo, C., Reinhold, A.G., Foster, E.M., Cost analysis of maternal disease associated with suboptimal breastfeeding. Obstet Gynecol 122 (2013), 111–119.
13. 13 Poindexter, B.B., Ehrenkranz, R.A., Stoll, B.J., Wright, L.L., Poole, W.K., Oh, W., et al. Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infants. Pediatrics 113 (2004), 1209–1215.
14. 14 Yee, W.H., Soraisham, A.S., Shah, V.S., Aziz, K., Yoon, W., Lee, S.K., et al. Incidence and timing of presentation of necrotizing enterocolitis in preterm infants. Pediatrics 129 (2012), e298–e304.
15. 15 Fitzgibbons, S.C., Ching, Y., Yu, D., Carpenter, J., Kenny, M., Weldon, C., et al. Mortality of necrotizing enterocolitis expressed by birth weight categories. J Pediatr Surg 44 (2009), 1072–1075 discussion 5-6.
16. 16 Heron, M., Hoyert, D., Murphy, S., Xu, J., Kochanek, K., Tejada-Vera, B., Deaths: Final data for 2006. Contract No 14. 2009, National Vital Statistics System, Hyattsville, MD.
17. 17 Kung, H.-C., Hoyert, D.L., Xu, J., Murphy, S.L., Deaths: final data for 2005. Natl Vital Stat Rep 56 (2008), 1–120.
18. 18 Meier, P.P., Engstrom, J.L., Mingolelli, S.S., Miracle, D.J., Kiesling, S., The Rush Mothers’ Milk Club: breastfeeding interventions for mothers with very-low-birth-weight infants. J Obstet Gynecol Neonatal Nurs 33 (2004), 164–174.
19. 19 Meier, P.P., Patel, A.L., Bigger, H.R., Rossman, B., Engstrom, J.L., Supporting breastfeeding in the neonatal intensive care unit: rush Mother's Milk Club as a case study of evidence-based care. Pediatr Clin North Am 60 (2013), 209–226.
20. 20 Patel, A.L., Johnson, T.J., Engstrom, J.L., Fogg, L.F., Jegier, B.J., Bigger, H.R., et al. Impact of early human milk on sepsis and health-care costs in very low birth weight infants. J Perinatol 33 (2013), 514–519.
21. 21 Neifert, M.R., Prevention of breastfeeding tragedies. Pediatr Clin North Am 48 (2001), 273–297.
22. 22 Forray, A., Foster, D., Substance use in the perinatal period. Curr Psychiatry Rep, 17, 2015, 91.
23. 23 Johnson, T.J., Patel, A.L., Jegier, B.J., Engstrom, J.L., Meier, P.P., Cost of morbidities in very low birth weight infants. J Pediatr 162 (2013), 243–249 e1.
24. 24 Centers for Medicare and Medicaid Services. The Center for Consumer Information and Insurance Oversight: Medical loss ratio. 2015, Centers for Medicare and Medicaid Services, Baltimore, MD http://www.cms.gov/CCIIO/Programs-and-Initiatives/Health-Insurance-Market-Reforms/Medical-Loss-Ratio.html Accessed March 2, 2015.
25. 25 Centers for Medicare and Medicaid Services. Medicare provider utilization and payment data: Physician and other supplier. 2015, Centers for Medicare and Medicaid Services, Baltimore, MD https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/Medicare-Provider-Charge-Data/Physician-and-Other-Supplier.html Accessed August 29, 2015.
26. 26 U.S. Department of Labor, Bureau of Labor Statistics. CPI Inflation Calculator. 2015 Washington, DC http://www.bls.gov/data/inflation_calculator.htm Accessed August 31, 2015.
27. 27 Hirth, R.A., Chernew, M.E., Miller, E., Fendrick, A.M., Weissert, W.G., Willingness to pay for a quality-adjusted life year: in search of a standard. Med Decis Making 20 (2000), 332–342.
28. 28 Mathews, T.J., MacDorman, M.F., Infant mortality statistics from the 2010 period linked birth/infant data set. Natl Vital Stat Rep 62 (2013), 1–26.
29. 29 Ganapathy, V., Hay, J.W., Kim, J.H., Costs of necrotizing enterocolitis and cost-effectiveness of exclusively human milk-based products in feeding extremely premature infants. Breastfeed Med 7 (2012), 29–37.
30. 30 Bisquera, J.A., Cooper, T.R., Berseth, C.L., Impact of necrotizing enterocolitis on length of stay and hospital charges in very low birth weight infants. Pediatrics 109 (2002), 423–428.
31. 31 Johnson, T.J., Patel, A.L., Bigger, H.R., Engstrom, J.L., Meier, P.P., Economic benefits and costs of human milk feedings: a strategy to reduce the risk of prematurity-related morbidities in very-low-birth-weight infants. Adv Nutr 5 (2014), 207–212.
32. 32 Hull, M.A., Fisher, J.G., Gutierrez, I.M., Jones, B.A., Kang, K.H., Kenny, M., et al. Mortality and management of surgical necrotizing enterocolitis in very low birth weight neonates: a prospective cohort study. J Am Coll Surg 218 (2014), 1148–1155.
33. 33 Johnson, T.J., Patel, A.L., Bigger, H.R., Engstrom, J.L., Meier, P.P., Cost savings of human milk as a strategy to reduce the incidence of necrotizing enterocolitis in very low birth weight infants. Neonatology 107 (2015), 271–276.
34. 34 Guthrie, S.O., Gordon, P.V., Thomas, V., Thorp, J.A., Peabody, J., Clark, R.H., Necrotizing enterocolitis among neonates in the United States. J Perinatol 23 (2003), 278–285.
35. 35 Guillet, R., Stoll, B.J., Cotten, C.M., Gantz, M., McDonald, S., Poole, W.K., et al. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants. Pediatrics 117 (2006), e137–e142.
36. 36 Llanos, A.R., Moss, M.E., Pinzon, M.C., Dye, T., Sinkin, R.A., Kendig, J.W., Epidemiology of neonatal necrotising enterocolitis: a population-based study. Paediatr Perinat Epidemiol 16 (2002), 342–349.
37. 37 Tzialla, C., Borghesi, A., Perotti, G.F., Garofoli, F., Manzoni, P., Stronati, M., Use and misuse of antibiotics in the neonatal intensive care unit. J Matern Fetal Neonatal Med 25:Suppl 4 (2012), 35–37.
38. 38 Cristofalo, E.A., Schanler, R.J., Blanco, C.L., Sullivan, S., Trawoeger, R., Kiechl-Kohlendorfer, U., et al. Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants. J Pediatr 163 (2013), 1592–1595.e1.
39. 39 Sullivan, S., Schanler, R.J., Kim, J.H., Patel, A.L., Trawoger, R., Kiechl-Kohlendorfer, U., et al. An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk-based products. J Pediatr 156 (2010), 562–567.e1.
40. 40 Hake-Brooks, S.J., Anderson, G.C., Kangaroo care and breastfeeding of mother-preterm infant dyads 0-18 months: a randomized, controlled trial. Neonatal Netw 27 (2008), 151–159.
41. 41 Callen, J., Pinelli, J., A review of the literature examining the benefits and challenges, incidence and duration, and barriers to breastfeeding in preterm infants. Adv Neonatal Care 5 (2005), 72–88 quiz 89-92.
42. 42 Callen, J., Pinelli, J., Atkinson, S., Saigal, S., Qualitative analysis of barriers to breastfeeding in very-low-birthweight infants in the hospital and postdischarge. Adv Neonatal Care 5 (2005), 93–103.
43. 43 Heiman, H., Schanler, R.J., Benefits of maternal and donor human milk for premature infants. Early Hum Dev 82 (2006), 781–787.
44. 44 Hair, A.B., Hawthorne, K.M., Chetta, K.E., Abrams, S.A., Human milk feeding supports adequate growth in infants