Fcγ-receptor IIa-mediated Src Signaling Pathway is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection

PLoS Pathogens

Volumn 12, Issue 12, 2016, Pages

  Furuyama, Wakako ^a   Marzi, Andrea ^b   Carmody, Aaron B ^b   Maruyama, Junki ^a   Kuroda, Makoto ^a,e   Miyamoto, Hiroko ^a   Nanbo, Asuka ^c   Manzoor, Rashid ^a   Yoshida, Reiko ^a   Igarashi, Manabu ^a   Feldmann, Heinz ^b   Takada, Ayato ^a,d  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF ZAMBIA   (Zambia)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO N (2,5 DIBROMOPHENYL) 3 HYDROXYCROTONAMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FC RECEPTOR IIA; FOSTAMATINIB; MANUMYCIN; FC RECEPTOR; PROTEIN TYROSINE KINASE; VIRUS ANTIBODY;

ANIMAL CELL; ANTIBODY DEPENDENT ENHANCEMENT; ARTICLE; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; EBOLA HEMORRHAGIC FEVER; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NONHUMAN; ONCOGENE SRC; PHAGOCYTOSIS; PINOCYTOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPTAKE ASSAY; VIRUS ENTRY; WESTERN BLOTTING; ANIMAL; CHLOROCEBUS AETHIOPS; HEK293 CELL LINE; IMMUNOLOGY; JURKAT CELL LINE; K-562 CELL LINE; METABOLISM; VERO CELL LINE;

ANIMALS; ANTIBODIES, VIRAL; ANTIBODY-DEPENDENT ENHANCEMENT; CERCOPITHECUS AETHIOPS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HEMORRHAGIC FEVER, EBOLA; HUMANS; JURKAT CELLS; K562 CELLS; RECEPTORS, IGG; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; VERO CELLS; VIRUS INTERNALIZATION;

EID: 85008162784     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006139     Document Type: Article

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