Shiga toxin increases formation of clathrin-coated pits through syk kinase

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Utskarpen, Audrun ^a,b   Massol, Ramiro ^c   van Deurs, Bo ^d   Lauvrak, Silje Ugland ^a,b   Kirchhausen, Tomas ^e   Sandvig, Kirsten ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN; PROTEIN AP 2; PROTEIN KINASE SYK; SHIGA TOXIN; TRANSFERRIN; UNCLASSIFIED DRUG; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ARTICLE; CELL MEMBRANE; CLATHRIN COATED PIT; COATED PIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCYTOSIS; HUMAN; HUMAN CELL; INTERNALIZATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPINNING DISK CONFOCAL MICROSCOPY; DRUG EFFECT; HELA CELL; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; ULTRASTRUCTURE;

ADAPTOR PROTEIN COMPLEX 2; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CLATHRIN; COATED PITS, CELL-MEMBRANE; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, ELECTRON; PROTEIN-TYROSINE KINASES; SHIGA TOXIN;

EID: 77955596721     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010944     Document Type: Article

References (28)

1. Sandvig K (2005) The Shiga toxins: Properties and action on cells. In: Alouf J, Popoff MR, eds. The comprehensive sourcebook of bacterial protein toxins Academic Press. pp 310-322.
2. Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, et al. (1992) Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature 358: 510-512.
3. Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989) Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1. J Cell Biol 108: 1331-1343.
4. Torgersen ML, Lauvrak SU, Sandvig K (2005) The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin. FEBS J 272: 4103-4113.
5. Mori T, Kiyokawa N, Katagiri YU, Taguchi T, Suzuki T, et al. (2000) Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain participates in B-cell receptor-mediated apoptosis by regulating lyn kinase activity in human B cells. Exp Hematol 28: 1260-1268.
6. Katagiri YU, Mori T, Nakajima H, Katagiri C, Taguchi T, et al. (1999) Activation of Src family kinase yes induced by Shiga toxin binding to globotriaosyl ceramide (Gb3/CD77) in low density, detergent-insoluble microdomains. J Biol Chem 274: 35278-35282.
7. Walchli S, Skanland SS, Gregers TF, Lauvrak SU, Torgersen ML, et al. (2007) The MAP Kinase p38 Links Shiga Toxin Dependent Signaling and Trafficking. Mol Biol Cell 19: 95-104.
8. Torgersen ML, Walchli S, Grimmer S, Skanland SS, Sandvig K (2007) Protein Kinase C{delta} Is Activated by Shiga Toxin and Regulates Its Transport. J Biol Chem 282: 16317-16328.
9. Lauvrak SU, Walchli S, Iversen TG, Slagsvold HH, Torgersen ML, et al. (2006) Shiga toxin regulates its entry in a Syk-dependent manner. Mol Biol Cell 17: 1096-1109.
10. Walchli S, Aasheim HC, Skanland SS, Spilsberg B, Torgersen ML, et al. (2009) Characterization of clathrin and Syk interaction upon Shiga toxin binding. Cell Signal 21: 1161-1168.
11. Wilde A, Beattie EC, Lem L, Riethof DA, Liu SH, et al. (1999) EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96: 677-687.
12. Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006) Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. Mol Cell Biol 26: 389-401.
13. Connolly JL, Green SA, Greene LA (1984) Comparison of rapid changes in surface morphology and coated pit formation of PC12 cells in response to nerve growth factor, epidermal growth factor, and dibutyryl cyclic AMP. J Cell Biol 98: 457-465.
14. Beattie EC, Howe CL, Wilde A, Brodsky FM, Mobley WC (2000) NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. J Neurosci 20: 7325-7333.
15. Ehrlich M, Boll W, van Oijen A, Hariharan R, Chandran K, et al. (2004) Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell 118: 591-605.
16. Boucrot E, Saffarian S, Massol R, Kirchhausen T, Ehrlich M (2006) Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res 312: 4036-4048.
17. Saffarian S, Cocucci E, Kirchhausen T (2009) Distinct dynamics of endocytic clathrin-coated pits and coated plaques. PLoS Biol 7: e1000191.
18. Loerke D, Mettlen M, Yarar D, Jaqaman K, Jaqaman H, et al. (2009) Cargo and dynamin regulate clathrin-coated pit maturation. PLoS Biol 7: e57.
19. Massol RH, Boll W, Griffin AM, Kirchhausen T (2006) A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proc Natl Acad Sci U S A 103: 10265-10270.
20. Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, et al. (2006) Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 10: 839-850.
21. Jaqaman K, Loerke D, Mettlen M, Kuwata H, Grinstein S, et al. (2008) Robust single-particle tracking in live-cell time-lapse sequences. Nat Methods 5: 695-702.
22. Kirchhausen T (2009) Imaging endocytic clathrin structures in living cells. Trends Cell Biol 19: 596-605.
23. Chakrabandhu K, Huault S, Garmy N, Fantini J, Stebe E, et al. (2008) The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand. Cell Death Differ 15: 1824-1837.
24. Shimizu T, Hamabata T, Yoshiki A, Hori T, Ito S, et al. (2003) An association of 27- and 40-kDa molecules with glycolipids that bind A-B bacterial enterotoxins to cultured cells. Biochim Biophys Acta 1612: 186-194.
25. Lau C, Wang X, Song L, North M, Wiehler S, et al. (2008) Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization. J Immunol 180: 870-880.
26. Johannes L, Tenza D, Antony C, Goud B (1997) Retrograde transport of KDEL-bearing B-fragment of Shiga toxin. J Biol Chem 272: 19554-19561.
27. Boucrot E, Kirchhausen T (2007) Endosomal recycling controls plasma membrane area during mitosis. Proc Natl Acad Sci U S A 104: 7939-7944.
28. Hommelgaard AM, Lerdrup M, van Deurs B (2004) Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol Biol Cell 15: 1557-1567.