Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study

American Journal of Transplantation

Volumn 17, Issue 5, 2017, Pages 1334-1345

  Singer, J P ^a   Katz, P P ^a   Soong, A ^a   Shrestha, P ^a   Huang, D ^a   Ho, J ^a   Mindo, M ^a   Greenland, J R ^a   Hays, S R ^a   Golden, J ^a   Kukreja, J ^a   Kleinhenz, M E ^a   Shah, R J ^a   Blanc, P D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

clinical decision making; clinical research practice; epidemiology; geriatrics; lung transplantation pulmonology; organ allocation; quality of life (QOL)

Indexed keywords

ADULT; AGED; ARTICLE; BODY MASS; COHORT ANALYSIS; DISABILITY; EXERCISE; FEMALE; GRAFT SURVIVAL; GROUPS BY AGE; HEALTH CARE MANAGEMENT; HUMAN; LUNG ALLOCATION SCORE; LUNG DISEASE; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OUTCOME VARIABLE; PHYSICAL DISABILITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; SHORT FORM 12; SIX MINUTE WALK TEST; UNITED STATES; ADOLESCENT; FOLLOW UP; HEALTH CARE ORGANIZATION; LONGITUDINAL STUDY; MIDDLE AGED; PROGNOSIS; QUALITY ADJUSTED LIFE YEAR; QUESTIONNAIRE; RESOURCE ALLOCATION; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; FEMALE; FOLLOW-UP STUDIES; HEALTH CARE RATIONING; HUMANS; LONGITUDINAL STUDIES; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; QUALITY OF LIFE; QUALITY-ADJUSTED LIFE YEARS; RESOURCE ALLOCATION; SURVEYS AND QUESTIONNAIRES; YOUNG ADULT;

EID: 85007575530     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.14081     Document Type: Article

References (56)

1. Thabut G, Ravaud P, Christie JD, et al. Determinants of the survival benefit of lung transplantation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008; 177: 1156–1163.
2. Yusen RD, Christie JD, Edwards LB, et al. The Registry of the International Society for Heart and Lung Transplantation: Thirtieth adult lung and heart-lung transplant report–2013; focus theme: Age. J Heart Lung Transplant 2013; 32: 965–978.
3. Egan TM, Murray S, Bustami RT, et al. Development of the new lung allocation system in the United States. Am J Transplant 2006; 6(5 Pt 2): 1212–1227.
4. George TJ, Beaty CA, Kilic A, Shah PD, Merlo CA, Shah AS. Outcomes and temporal trends among high-risk patients after lung transplantation in the United States. J Heart Lung Transplant 2012; 31: 1182–1191.
5. Hoopes CW, Kukreja J, Golden J, Davenport DL, Diaz-Guzman E, Zwischenberger JB. Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation. J Thorac Cardiovasc Surg 2013; 145: 862–867.
6. UNOS Data Report. [Website] 2016 [cited 2016 May 14]. Available from: https://optn.transplant.hrsa.gov/data/view-data-reports/national-data/#;.
7. Maxwell BG, Mooney JJ, Lee PH, et al. Increased resource use in lung transplant admissions in the lung allocation score era. Am J Respir Crit Care Med 2015; 191: 302–308.
8. Maxwell BG, Levitt JE, Goldstein BA, et al. Impact of the lung allocation score on survival beyond 1 year. Am J Transplant 2014; 14: 2288–2294.
9. Dew MA, DiMartini AF. Psychological disorders and distress after adult cardiothoracic transplantation. J Cardiovasc Nurs 2005; 20(5 Suppl): S51–S66.
10. Dew MA, DiMartini AF, DeVito Dabbs AJ, et al. Onset and risk factors for anxiety and depression during the first 2 years after lung transplantation. Gen Hosp Psychiatry 2012; 34: 127–138.
11. Dew MA, Rosenberger EM, Myaskovsky L, et al. Depression and anxiety as risk factors for morbidity and mortality after organ transplantation: A systematic review and meta-analysis. Transplantation 2015; 100: 988–1003.
12. Suhling H, Knuth C, Haverich A, Lingner H, Welte T, Gottlieb J. Employment after lung transplantation–a single-center cross-sectional study. Dtsch Arztebl Int 2015; 112: 213–219.
13. Cohen DG, Christie JD, Anderson BJ, et al. Cognitive function, mental health, and health-related quality of life after lung transplantation. Ann Am Thorac Soc 2014; 11: 522–530.
14. Courtwright AM, Salomon S, Lehmann LS, Wolfe DJ, Goldberg HJ. The effect of pretransplant depression and anxiety on survival following lung transplant: A meta-analysis. Psychosomatics 2016; 57: 238–245.
15. Hoffman BM, Blumenthal JA, Carney RC, et al. Changes in neurocognitive functioning following lung transplantation. Am J Transplant 2012; 12: 2519–2525.
16. Kugler C, Fischer S, Gottlieb J, et al. Symptom experience after lung transplantation: Impact on quality of life and adherence. Clin Transplant 2007; 21: 590–596.
17. Langer D, Burtin C, Schepers L, et al. Exercise training after lung transplantation improves participation in daily activity: A randomized controlled trial. Am J Transplant 2012; 12: 1584–1592.
18. Lanuza DM, Lefaiver CA, Brown R, et al. A longitudinal study of patients' symptoms before and during the first year after lung transplantation. Clin Transplant 2012; 26: E576–E589.
19. Rosenberger EM, DiMartini AF, DeVito Dabbs AJ, et al. Psychiatric predictors of long-term transplant-related outcomes in lung transplant recipients. Transplantation 2016; 100: 239–247.
20. Smith PJ, Blumenthal JA, Carney RM, et al. Neurobehavioral functioning and survival following lung transplantation. Chest 2014; 145: 604–611.
21. Smith PJ, Blumenthal JA, Trulock EP, et al. Psychosocial predictors of mortality following lung transplantation. Am J Transplant 2016; 16: 271–277.
22. Smith PJ, Rivelli S, Waters A, et al. Neurocognitive changes after lung transplantation. Ann Am Thorac Soc 2014; 11: 1520–1527.
23. Singer LG, Chowdhury NA, Faughnan ME, et al. Effects of recipient age and diagnosis on health-related quality-of-life benefit of lung transplantation. Am J Respir Crit Care Med 2015; 192: 965–973.
24. Singer JP, Katz PP, Chen H, et al. Lung transplantation improves health-related quality of life, particularly in those with the poorest status before transplant. Chest 2011; 140: 1023A (abstract).
25. Singer JP, Katz PP, Chen J, et al. Change in disability is a determinant of quality of life in persons undergoing lung transplant. J Heart Lung Transplant 2012; 31(S): 504 (abstract).
26. Singer JP, Chen J, Dean YM, et al. Lung transplant improves health related quality of life for many, but not all, patients with advanced lung disease. Am J Respir Crit Care Med 2013; 191: A3775 (abstract).
27. Singer JP, Katz P, Dean YM, et al. Frailty is common in lung transplant candidates and associated with poorer health-related quality of life. J Heart Lung Transplant 2013; 32: S892 (abstract).
28. Singer JP, Blanc PD, Dean YM, et al. Development and validation of a lung transplant-specific disability questionnaire. Thorax 2014; 69: 445–450.
29. Singer JP, Soong A, Shrestha P, et al. Lung transplantation improves health-related quality of life for most, but not all, with advanced lung disease. Am J Respir Crit Care Med 2016; 193: A4670 (abstract).
30. Shah RJ, Collard HR, Soong A, et al. Changes in quality of life after lung transplantation in recipients with connective tissue related ILD (CTD-ILD). Am J Respir Crit Care Med 2016; 193: A4666 (abstract).
31. McDowell I. Measuring health: A guide to rating scales and questionnaires, 3rd ed. New York: Oxford University Press; 2006.
32. Stewart AL, Ware Jr JE. Measuring functioning and well-being: The medical outcomes study approach. Durham, NC: Duke University Press; 1992.
33. Ware Jr J, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: Construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34: 220–233.
34. Busija L, Pausenberger E, Haines TP, Haymes S, Buchbinder R, Osborne RH. Adult measures of general health and health-related quality of life: Medical Outcomes Study Short Form 36-Item (SF-36) and Short Form 12-Item (SF-12) Health Surveys, Nottingham Health Profile (NHP), Sickness Impact Profile (SIP), Medical Outcomes Study Short Form 6D (SF-6D), Health Utilities Index Mark 3 (HUI3), Quality of Well-Being Scale (QWB), and Assessment of Quality of Life (AQoL). Arthritis Care Res (Hoboken) 2011; 63(Suppl 11): S383–S412.
35. Chen H, Eisner MD, Katz PP, Yelin EH, Blanc PD. Measuring disease-specific quality of life in obstructive airway disease—Validation of a modified version of the airways questionnaire 20. Chest 2006; 129: 1644–1652.
36. Euroqol Group. EuroQol–a new facility for the measurement of health-related quality of life. The EuroQol Group. Health Policy 1990; 16: 199–208.
37. Marra CA, Woolcott JC, Kopec JA, et al. A comparison of generic, indirect utility measures (the HUI2, HUI3, SF-6D, and the EQ-5D) and disease-specific instruments (the RAQoL and the HAQ) in rheumatoid arthritis. Soc Sci Med 2005; 60: 1571–1582.
38. Coteur G, Feagan B, Keininger DL, Kosinski M. Evaluation of the meaningfulness of health-related quality of life improvements as assessed by the SF-36 and the EQ-5D VAS in patients with active Crohn's disease. Aliment Pharmacol Ther 2009; 29: 1032–1041.
39. Brandt EN, Pope AM. eds. Enabling America: Assessing the role of rehabilitation science and engineering. Washington, DC: National Academies Press; 1997.
40. Nagi SZ. An epidemiology of disability among adults in the United States. Milbank Mem Fund Q Health Soc 1976; 54: 439–467.
41. Abecassis M, Bridges ND, Clancy CJ, et al. Solid-organ transplantation in older adults: Current status and future research. Am J Transplant 2012; 12: 2608–2622.
42. Singer JP, Chen J, Katz PP, Blanc PD, Kagawa-Singer M, Stewart AL. Defining novel health-related quality of life domains in lung transplantation: A qualitative analysis. Qual Life Res 2015; 24: 1521–1533.
43. Nagi SZ. Disability concepts revisited: Implications for prevention. Washington, DC: National Academy Press; 1991.
44. Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986; 51: 1173–1182.
45. Benzo R, Farrell MH, Chang CC, et al. Integrating health status and survival data: The palliative effect of lung volume reduction surgery. Am J Respir Crit Care Med 2009; 180: 239–246.
46. DerHovanessian A, Todd JL, Zhang A, et al. Validation and refinement of chronic lung allograft dysfunction phenotypes in bilateral and single lung recipients. Ann Am Thorac Soc 2016; 13: 627–635.
47. Todd JL, Jain R, Pavlisko EN, et al. Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction. Am J Respir Crit Care Med 2014; 189: 159–166.
48. Hoffman BM, Stonerock GL, Smith PJ, et al. Development and psychometric properties of the Pulmonary-specific Quality-of-Life Scale in lung transplant patients. J Heart Lung Transplant 2015; 34: 1058–1065.
49. Myaskovsky L, Dew MA, McNulty ML, et al. Trajectories of change in quality of life in 12-month survivors of lung or heart transplant. Am J Transplant 2006; 6: 1939–1947.
50. Kugler C, Strueber M, Tegtbur U, Niedermeyer J, Haverich A. Quality of life 1 year after lung transplantation. Prog Transplant 2004; 14: 331–336.
51. Yusen RD, Edwards LB, Kucheryavaya AY, et al. The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Lung and Heart-Lung Transplantation Report–2015; Focus Theme: Early Graft Failure. J Heart Lung Transplant 2015; 34: 1264–1277.
52. Yusen RD. Technology and outcomes assessment in lung transplantation. Proc Am Thorac Soc 2009; 6: 128–136.
53. Yusen RD. Lung transplantation outcomes: The importance and inadequacies of assessing survival. Am J Transplant 2009; 9: 1493–1494.
54. Singer JP, Chen J, Blanc PD, Leard LE, Kukreja J, Chen H. A thematic analysis of quality of life in lung transplant: The existing evidence and implications for future directions. Am J Transplant 2013; 13: 839–850.
55. Song MK, Devito Dabbs AJ, Studer SM, Arnold RM, Pilewski JM. Exploring the meaning of chronic rejection after lung transplantation and its impact on clinical management and caregiving. J Pain Symptom Manage 2010; 40: 246–255.
56. De Vito Dabbs A, Dew MA, Stilley CS, et al. Psychosocial vulnerability, physical symptoms and physical impairment after lung and heart-lung transplantation. J Heart Lung Transplant 2003; 22: 1268–1275.