Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease

Neurobiology of Aging

Volumn 51, Issue , 2017, Pages 83-96

  Harach, Taoufiq ^a   Jammes, Fabien ^a   Muller, Charles ^b   Duthilleul, Nicolas ^a   Cheatham, Victoria ^a   Zufferey, Valentin ^a   Cheatham, David ^b   Lukasheva, Yelizaveta A ^a,b   Lasser, Theo ^a   Bolmont, Tristan ^a,b  

^a EPFL   (Switzerland)

^b Stemedica International SA   (Switzerland)

Author keywords

Alzheimer's disease; Cerebral Abeta amyloidosis; Human adult ischemia tolerant mesenchymal stem cells; Intranasal application; Intravenous delivery; Stem cell factors; Transgenic mice

Indexed keywords

AMYLOID BETA PROTEIN; VASCULOTROPIN A; AUTACOID; CYTOKINE;

ADULT; ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN PARENCHYMA; BRAIN TISSUE; CELL MIGRATION; CELLULAR DISTRIBUTION; CEREBROVASCULATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME DEGRADATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFANT; ISCHEMIA; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PARENCHYMA; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SAFETY; TRANSGENIC MOUSE; UPREGULATION; VASCULAR AMYLOIDOSIS; ANIMAL; BRAIN; CELL CULTURE; CELL MOTION; DISEASE MODEL; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MOLECULARLY TARGETED THERAPY; PROCEDURES;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; CELL MOVEMENT; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; INFLAMMATION MEDIATORS; INJECTIONS, INTRAVENOUS; MESENCHYMAL STEM CELL TRANSPLANTATION; MICE, TRANSGENIC; MOLECULAR TARGETED THERAPY;

EID: 85007557395     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.11.009     Document Type: Article

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