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Volumn 17, Issue 1, 2016, Pages

Mutanalyst, an online tool for assessing the mutational spectrum of epPCR libraries with poor sampling

Author keywords

Confidence; Directed evolution; Enzyme engineering; Error prone mutagenesis; Mutagenesis; Mutational spectrum; Small sampling; Standard error

Indexed keywords

FISHER INFORMATION MATRIX; MUTAGENESIS; POISSON DISTRIBUTION; POLYMERASE CHAIN REACTION; SAMPLING;

EID: 85007418136     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/s12859-016-0996-7     Document Type: Article
Times cited : (5)

References (9)
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  • 2
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    • Acevedo-Rocha, C.G.1    Reetz, M.T.2    Nov, Y.3
  • 4
    • 84918832461 scopus 로고    scopus 로고
    • Lessons from diversity of directed evolution experiments by an analysis of 3,000 mutations
    • Zhao J, Kardashliev T, Joëlle RuffA, Bocola M, Schwaneberg U. Lessons from diversity of directed evolution experiments by an analysis of 3,000 mutations. Biotechnol Bioeng. 2014;111:2380-9.
    • (2014) Biotechnol Bioeng , vol.111 , pp. 2380-2389
    • Zhao, J.1    Kardashliev, T.2    Joëlle Ruff, A.3    Bocola, M.4    Schwaneberg, U.5
  • 5
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  • 6
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    • User-friendly algorithms for estimating completeness and diversity in randomized protein-encoding libraries
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    • Patrick, W.M.1    Firth, A.E.2    Blackburn, J.M.3
  • 7
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    • Statistics of protein library construction
    • Firth AE, Patrick WM. Statistics of protein library construction. Bioinformatics. 2005;21:3314-5.
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    • Firth, A.E.1    Patrick, W.M.2
  • 8
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    • GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries
    • Firth AE, Patrick WM. GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries. Nucleic Acids Res. 2008;36(Web Server issue):W281-5.
    • (2008) Nucleic Acids Res , vol.36 , Issue.WEB SERVER ISSUE , pp. W281-W285
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  • 9
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    • A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries
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    • (2005) Nucleic Acids Res , vol.33 , pp. 3667-3677
    • Volles, M.J.1    Lansbury, P.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.