ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart

Circulation Research

Volumn 120, Issue 5, 2017, Pages 862-875

  Jin, Jung Kang ^a   Blackwood, Erik A ^a   Azizi, Khalid ^a   Thuerauf, Donna J ^a   Fahem, Asal G ^a   Hofmann, Christoph ^a,b,c   Kaufman, Randal J ^d   Doroudgar, Shirin ^a,b,c   Glembotski, Christopher C ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d BURNHAM INSTITUTE   (United States)

Author keywords

ATF6; cardiac myocyte; catalase; endoplasmic reticulum stress; ischemia; ischemia reperfusion injury; oxidative stress; protein folding; unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CATALASE; REACTIVE OXYGEN METABOLITE; TUNICAMYCIN; ATF6 PROTEIN, MOUSE;

ADENO ASSOCIATED VIRUS 9; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELL DEATH; CONTROLLED STUDY; DNA BINDING; DNA RESPONSIVE ELEMENT; ENDOPLASMIC RETICULUM STRESS; HEART FUNCTION; HELA CELL LINE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE; DEFICIENCY; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM; MYOCARDIAL REPERFUSION INJURY; NEWBORN; PATHOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; ANIMALS, NEWBORN; ENDOPLASMIC RETICULUM STRESS; HEK293 CELLS; HELA CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 85007198697     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.310266     Document Type: Article

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