IL1R9 is evolutionarily related to IL18BP and may function as an IL-18 receptor

Journal of Immunology

Volumn 198, Issue 1, 2017, Pages 270-278

  Booker, Chris S ^a   Grattan, David R ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN-18 BINDING PROTEIN; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOINFORMATICS; BRAIN NERVE CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE FUNCTION; GENE IDENTIFICATION; HABENULA; IL18RAP GENE; IL1R9 GENE; INTERLEUKIN 18 BINDING PROTEIN GENE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; BIOLOGY; GENETICS; HUMAN; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; RECEPTORS, INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-18; SEQUENCE HOMOLOGY;

EID: 85006995412     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500648     Document Type: Article

References (53)

1. Smith, D. E. 2011. The biological paths of IL-1 family members IL-18 and IL-33. J. Leukoc. Biol. 89: 383-392.
2. Heaney, M. L., and D. W. Golde. 1996. Soluble cytokine receptors. Blood 87: 847-857.
3. Kim, S. H., M. Eisenstein, L. Reznikov, G. Fantuzzi, D. Novick, M. Rubinstein, and C. A. Dinarello. 2000. Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc. Natl. Acad. Sci. USA 97: 1190-1195.
4. Kato, Z., J. Jee, H. Shikano, M. Mishima, I. Ohki, H. Ohnishi, A. Li, K. Hashimoto, E. Matsukuma, K. Omoya, et al. 2003. The structure and binding mode of interleukin-18. Nat. Struct. Biol. 10: 966-971.
5. Aizawa, H., M. Kobayashi, S. Tanaka, T. Fukai, and H. Okamoto. 2012. Molecular characterization of the subnuclei in rat habenula. J. Comp. Neurol. 520: 4051-4066.
6. Sugama, S., B. P. Cho, H. Baker, T. H. Joh, J. Lucero, and B. Conti. 2002. Neurons of the superior nucleus of the medial habenula and ependymal cells express IL-18 in rat CNS. Brain Res. 958: 1-9.
7. Lein, E. S., M. J. Hawrylycz, N. Ao, M. Ayres, A. Bensinger, A. Bernard, A. F. Boe, M. S. Boguski, K. S. Brockway, E. J. Byrnes, et al. 2007. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445: 168-176.
8. Alboni, S., D. Cervia, B. Ross, C. Montanari, A. S. S. Gonzalez, M. Sanchez-Alavez, M. C. G. C. Marcondes, D. De Vries, S. Sugama, N. Brunello, et al. 2009. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain. J. Neuroimmunol. 214: 43-54.
9. Alboni, S., C. Montanari, C. Benatti, J. M. C. Blom, M. L. Simone, N. Brunello, F. Caggia, G. Guidotti, M. C. G. Marcondes, M. Sanchez-Alavez, et al. 2011. Constitutive and LPS-regulated expression of interleukin-18 receptor beta variants in the mouse brain. Brain Behav. Immun. 25: 483-493.
10. Allen Institute for Brain Science. 2009. Allen Mouse Brain Atlas. Available at: http://mouse.brain-map.org.
11. Novick, D., S. H. Kim, G. Fantuzzi, L. L. Reznikov, C. A. Dinarello, and M. Rubinstein. 1999. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 10: 127-136.
12. Watanabe, M., N. Goto, Y. Watanabe, S. Nishiguchi, K. Shimada, T. Yasunga, and H. Yamanishi. 2005. Evolution of interleukin-18 binding proteins and interleukin-1 receptor, type II proteins. Int. J. Mol. Med. 15: 561-566.
13. Xiang, Y., and B. Moss. 2001. Determination of the functional epitopes of human interleukin-18-binding protein by site-directed mutagenesis. J. Biol. Chem. 276: 17380-17386.
14. Krumm, B., X. Meng, Y. Li, Y. Xiang, and J. Deng. 2008. Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein. Proc. Natl. Acad. Sci. USA 105: 20711-20715.
15. Esteban, D. J., and R. M. L. Buller. 2004. Identification of residues in an orthopoxvirus interleukin-18 binding protein involved in ligand binding and species specificity. Virology 323: 197-207.
16. Krumm, B., X. Meng, Z. Wang, Y. Xiang, and J. Deng. 2012. A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein. PLoS Pathog. 8: e1002876.
17. Xiang, Y., and B. Moss. 2001. Correspondence of the functional epitopes of poxvirus and human interleukin-18-binding proteins. J. Virol. 75: 9947-9954.
18. Armougom, F., S. Moretti, O. Poirot, S. Audic, P. Dumas, B. Schaeli, V. Keduas, and C. Notredame. 2006. Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee. Nucleic Acids Res. 34: W604-W608.
19. Taly, J.-F., C. Magis, G. Bussotti, J.-M. Chang, P. Di Tommaso, I. Erb, J. Espinosa-Carrasco, C. Kemena, and C. Notredame. 2011. Using the T-Coffee package to build multiple sequence alignments of protein, RNA, DNA sequences and 3D structures. Nat. Protoc. 6: 1669-1682.
20. Taylor, W. R. 1986. The classification of amino acid conservation. J. Theor. Biol. 119: 205-218.
21. Abaza, A., J.-M. Soleilhac, J. Westendorf, M. Piel, I. Crevel, A. Roux, and F. Pirollet. 2003. M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis. J. Biol. Chem. 278: 27844-27852.
22. Katju, V. 2012. In with the old, in with the new: the promiscuity of the duplication process engenders diverse pathways for novel gene creation. Int. J. Evol. Biol. 2012: 341932.
23. Dinarello, C. A., D. Novick, S. Kim, and G. Kaplanski. 2013. Interleukin-18 and IL-18 binding protein. Front. Immunol. 4: 289.
24. Jin, H., R. J. Gardner, R. Viswesvaraiah, F. Muntoni, and R. G. Roberts. 2000. Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1-Xp21.3 mental retardation. Eur. J. Hum. Genet. 8: 87-94.
25. Long, M., N. W. VanKuren, S. Chen, and M. D. Vibranovski. 2013. New gene evolution: little did we know. Annu. Rev. Genet. 47: 307-333.
26. Vinckenbosch, N., I. Dupanloup, and H. Kaessmann. 2006. Evolutionary fate of retroposed gene copies in the human genome. Proc. Natl. Acad. Sci. USA 103: 3220-3225.
27. Abu Elhija, M., E. Lunenfeld, L. Persky, and M. Huleihel. 2008. Constitutive expression of IL-18 binding protein in murine testicular tissues and cells. Eur. Cytokine Netw. 19: 25-29.
28. Xiang, Y., and B. Moss. 2003. Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domain. J. Virol. 77: 2623-2630.
29. Born, T. L., D. E. Smith, K. E. Garka, B. R. Renshaw, J. S. Bertles, and J. E. Sims. 2000. Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling. J. Biol. Chem. 275: 29946-29954.
30. Khan, J. A., E. K. Brint, L. A. J. O'Neill, and L. Tong. 2004. Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL. J. Biol. Chem. 279: 31664-31670.
31. Valnegri, P., C. Montrasio, D. Brambilla, J. Ko, M. Passafaro, and C. Sala. 2011. The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPd and RhoGAP2. Hum. Mol. Genet. 20: 4797-4809.
32. Yoshida, T., M. Yasumura, T. Uemura, S.-J. Lee, M. Ra, R. Taguchi, Y. Iwakura, and M. Mishina. 2011. IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase d. J. Neurosci. 31: 13485-13499.
33. Francesconi, W., M. Sánchez-Alavez, F. Berton, S. Alboni, C. Benatti, S. Mori, W. Nguyen, E. Zorrilla, G. Moroncini, F. Tascedda, and B. Conti. 2016. The proinflammatory cytokine interleukin 18 regulates feeding by acting on the bed nucleus of the stria terminalis. J. Neurosci. 36: 5170-5180.
34. Qian, J., L. Zhu, Q. Li, N. Belevych, Q. Chen, F. Zhao, S. Herness, and N. Quan. 2012. Interleukin-1R3 mediates interleukin-1-induced potassium current increase through fast activation of Akt kinase. Proc. Natl. Acad. Sci. USA 109: 12189-12194.
35. Yoshida, T., T. Shiroshima, S.-J. Lee, M. Yasumura, T. Uemura, X. Chen, Y. Iwakura, and M. Mishina. 2012. Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule. J. Neurosci. 32: 2588-2600.
36. Nguyen, L., N. J. Rothwell, E. Pinteaux, and H. Boutin. 2011. Contribution of interleukin-1 receptor accessory protein B to interleukin-1 actions in neuronal cells. Neurosignals 19: 222-230.
37. Huang, Y., D. E. Smith, O. Ibáñez-Sandoval, J. E. Sims, and W. J. Friedman. 2011. Neuron-specific effects of interleukin-1b are mediated by a novel isoform of the IL-1 receptor accessory protein. J. Neurosci. 31: 18048-18059.
38. Smith, D. E., B. P. Lipsky, C. Russell, R. R. Ketchem, J. Kirchner, K. Hensley, Y. Huang, W. J. Friedman, V. Boissonneault, M.-M. Plante, et al. 2009. A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1. Immunity 30: 817-831.
39. Tsutsumi, N., T. Kimura, K. Arita, M. Ariyoshi, H. Ohnishi, T. Yamamoto, X. Zuo, K. Maenaka, E. Y. Park, N. Kondo, et al. 2014. The structural basis for receptor recognition of human interleukin-18. Nat. Commun. 5: 5340.
40. Zhao-Shea, R., S. R. DeGroot, L. Liu, M. Vallaster, X. Pang, Q. Su, G. Gao, O. J. Rando, G. E. Martin, O. George, et al. 2015. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nat. Commun. 6: 6770.
41. Harrington, L., X. Viñals, A. Herrera-Solís, A. Flores, C. Morel, S. Tolu, P. Faure, R. Maldonado, U. Maskos, and P. Robledo. 2016. Role of β4∗ nicotinic acetylcholine receptors in the habenulo-interpeduncular pathway in nicotine reinforcement in mice. Neuropsychopharmacology 41: 1790-1802.
42. Pang, X., L. Liu, J. Ngolab, R. Zhao-Shea, J. M. McIntosh, P. D. Gardner, and A. R. Tapper. 2016. Habenula cholinergic neurons regulate anxiety during nicotine withdrawal via nicotinic acetylcholine receptors. Neuropharmacology 107: 294-304.
43. Yaguchi, T., T. Nagata, D. Yang, and T. Nishizaki. 2010. Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity. Behav. Brain Res. 206: 47-51.
44. Curran, B., and J. J. O'Connor. 2001. The pro-inflammatory cytokine interleukin-18 impairs long-term potentiation and NMDA receptor-mediated transmission in the rat hippocampus in vitro. Neuroscience 108: 83-90.
45. Hedtjärn, M., A.-L. Leverin, K. Eriksson, K. Blomgren, C. Mallard, and H. Hagberg. 2002. Interleukin-18 involvement in hypoxic-ischemic brain injury. J. Neurosci. 22: 5910-5919.
46. Bach, A., B. H. Clausen, M. Møller, B. Vestergaard, C. N. Chi, A. Round, P. L. Sørensen, K. B. Nissen, J. S. Kastrup, M. Gajhede, et al. 2012. A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. Proc. Natl. Acad. Sci. USA 109: 3317-3322.
47. Cook, D. J., L. Teves, and M. Tymianski. 2012. Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature 483: 213-217.
48. Booker, C. 2012. Inflammation in type 2 diabetes and the neuroendocrine role of IL-18. PhD thesis, University of Otago, Dunedin, New Zealand. Available at: http://hdl.handle.net/10523/3719.
49. Conti, B., J. W. Jahng, C. Tinti, J. H. Son, and T. H. Joh. 1997. Induction of interferon-γ inducing factor in the adrenal cortex. J. Biol. Chem. 272: 2035-2037.
50. Yang, Y.-J. J., Z.-Y. Y. Wang, S.-H. H. Chen, and X.-R. R. Ge. 2005. Cloning and characterization of a new isoform of mouse interleukin-18. Acta Biochim. Biophys. Sin. (Shanghai) 37: 826-834.
51. Omoto, Y., K. Tokime, K. Yamanaka, K. Habe, T. Morioka, I. Kurokawa, H. Tsutsui, K. Yamanishi, K. Nakanishi, and H. Mizutani. 2006. Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment. J. Immunol. 177: 8315-8319.
52. Bellora, F., R. Castriconi, A. Doni, C. Cantoni, L. Moretta, A. Mantovani, A. Moretta, and C. Bottino. 2012. M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages. Eur. J. Immunol. 42: 1618-1626.
53. Dinarello, C. A. 2012. Membrane interleukin-18 revisits membrane IL-1α in T-helper type 1 responses. Eur. J. Immunol. 42: 1385-1387.