메뉴 건너뛰기




Volumn 61, Issue 2, 2013, Pages 256-264

Cardinal role of the intrarenal renin-angiotensin system in the pathogenesis of diabetic nephropathy

Author keywords

Angiotensinogen; Diabetic nephropathy; Kidney; Renin angiotensin system

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALBUMIN; AMLODIPINE; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; OLMESARTAN; PLACEBO; PROSTAGLANDIN F2 ALPHA; RAMIPRIL; TELMISARTAN; TRANDOLAPRIL;

EID: 85006847162     PISSN: 17088267     EISSN: 17088267     Source Type: Journal    
DOI: 10.2310/JIM.0b013e31827c28bb     Document Type: Conference Paper
Times cited : (54)

References (106)
  • 1
    • 0036178968 scopus 로고    scopus 로고
    • Diabetic nephropathy: How effective is treatment in clinical practice?
    • Joss N, Paterson KR, Deighan CJ, et al. Diabetic nephropathy: how effective is treatment in clinical practice? QJM. 2002;95:41-49.
    • (2002) QJM , vol.95 , pp. 41-49
    • Joss, N.1    Paterson, K.R.2    Deighan, C.J.3
  • 2
    • 0037223174 scopus 로고    scopus 로고
    • Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    • Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003;289:76-79.
    • (2003) JAMA , vol.289 , pp. 76-79
    • Mokdad, A.H.1    Ford, E.S.2    Bowman, B.A.3
  • 3
    • 38849125579 scopus 로고    scopus 로고
    • Prevalence of self-reported diagnosis of diabetes mellitus and associated risk factors in a national survey in the us population: SHIELD (Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes)
    • Bays HE, Bazata DD, Clark NG, et al. Prevalence of self-reported diagnosis of diabetes mellitus and associated risk factors in a national survey in the us population: SHIELD (Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes). BMC Public Health. 2007;7:277.
    • (2007) BMC Public Health , vol.7 , pp. 277
    • Bays, H.E.1    Bazata, D.D.2    Clark, N.G.3
  • 5
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among us adults: Findings from the third national health and nutrition examination survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among us adults: findings from the third national health and nutrition examination survey. JAMA. 2002;287:356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 6
    • 0000353575 scopus 로고
    • Intrarenal actions of angiotensin II in the pathogenesis of experimental hypertension
    • Laragh JH, Brenner BM, eds. New York, NY: Raven Press
    • Mitchell KD, Navar LG. Intrarenal actions of angiotensin II in the pathogenesis of experimental hypertension. In: Laragh JH, Brenner BM, eds. Hypertension: Pathophysiology, Diagnosis and Management. New York, NY: Raven Press; 1995:1437-1450.
    • (1995) Hypertension: Pathophysiology, Diagnosis and Management , pp. 1437-1450
    • Mitchell, K.D.1    Navar, L.G.2
  • 7
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: From physiology to the pathobiology of hypertension and kidney disease
    • Kobori H, Nangaku M, Navar LG, et al. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev. 2007; 59:251-287.
    • (2007) Pharmacol Rev , vol.59 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3
  • 8
    • 0043068157 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system and diabetic nephropathy
    • Carey RM, Siragy HM. The intrarenal renin-angiotensin system and diabetic nephropathy. Trends Endocrinol Metab. 2003;14:274-281.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 274-281
    • Carey, R.M.1    Siragy, H.M.2
  • 9
    • 0037478671 scopus 로고    scopus 로고
    • Angiotensin-(1-7) is an endogenous ligand for the G proteinYcoupled receptor MAS
    • Santos RA, Simoes e Silva AC, Maric C, et al. Angiotensin-(1-7) is an endogenous ligand for the G proteinYcoupled receptor MAS. Proc Natl Acad Sci U S A. 2003;100:8258-8263.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8258-8263
    • Santos, R.A.1    Simoes Silva E, A.C.2    Maric, C.3
  • 10
    • 34347205121 scopus 로고    scopus 로고
    • Chapter 1: Molecular aspects of the renal renin-angiotensin system
    • Re RN DiPette DJ Schiffrin EL Et Al Eds. Oxfordshire UK: Taylor & Francis Medical
    • Navar LG, Prieto-Carrasquero MC, Kobori H. Chapter 1: molecular aspects of the renal renin-angiotensin system. In: Re RN, DiPette DJ, Schiffrin EL, et al, eds. Molecular Mechanisms in Hypertension. Oxfordshire, UK: Taylor & Francis Medical; 2006:3-14.
    • (2006) Molecular Mechanisms in Hypertension , pp. 3-14
    • Navar, L.G.1    Prieto-Carrasquero, M.C.2    Kobori, H.3
  • 11
    • 0028010788 scopus 로고
    • Tissue angiotensin system in cardiovascular medicine. A paradigm shift?
    • Dzau VJ, Re R. Tissue angiotensin system in cardiovascular medicine. A paradigm shift? Circulation. 1994;89:493-498.
    • (1994) Circulation , vol.89 , pp. 493-498
    • Dzau, V.J.1    Re, R.2
  • 12
    • 0033964491 scopus 로고    scopus 로고
    • The brain renin-angiotensin system modulates angiotensin II-Yinduced hypertension and cardiac hypertrophy
    • Baltatu O, Silva JA Jr, Ganten D, et al. The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy. Hypertension. 2000;35:409-412.
    • (2000) Hypertension , vol.35 , pp. 409-412
    • Baltatu, O.1    Silva Jr., J.A.2    Ganten, D.3
  • 13
    • 0030838414 scopus 로고    scopus 로고
    • Compartmentalization of angiotensin II generation in the dog heart evidence for independent mechanisms in intravascular and interstitial spaces
    • Dell'Italia LJ, Meng QC, Balcells E, et al. Compartmentalization of angiotensin II generation in the dog heart evidence for independent mechanisms in intravascular and interstitial spaces. J Clin Invest. 1997;100:253-258.
    • (1997) J Clin Invest , vol.100 , pp. 253-258
    • Dell'Italia, L.J.1    Meng, Q.C.2    Balcells, E.3
  • 14
    • 0033947547 scopus 로고    scopus 로고
    • Role of adrenal renin-angiotensin system in the control of aldosterone secretion in sodium-restricted rats
    • Mazzocchi G, Malendowicz LK, Markowska A, et al. Role of adrenal renin-angiotensin system in the control of aldosterone secretion in sodium-restricted rats. Am J Physiol Endocrinol Metab. 2000; 278:E1027YE1030.
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Mazzocchi, G.1    Malendowicz, L.K.2    Markowska, A.3
  • 15
    • 0032425158 scopus 로고    scopus 로고
    • Angiotensin I-to-II conversion in the human renal vascular bed
    • Danser AH, Admiraal PJ, Derkx FH, et al. Angiotensin I-to-II conversion in the human renal vascular bed. J Hypertens. 1998;16:2051-2056.
    • (1998) J Hypertens , vol.16 , pp. 2051-2056
    • Danser, A.H.1    Admiraal, P.J.2    Derkx, F.H.3
  • 16
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141-1148.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3
  • 17
    • 0036181980 scopus 로고    scopus 로고
    • Regulation of intrarenal angiotensin II in hypertension
    • Navar LG, Harrison-Bernard LM, Nishiyama A, et al. Regulation of intrarenal angiotensin II in hypertension. Hypertension. 2002; 39:316-322.
    • (2002) Hypertension , vol.39 , pp. 316-322
    • Navar, L.G.1    Harrison-Bernard, L.M.2    Nishiyama, A.3
  • 18
    • 0025056511 scopus 로고
    • In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system
    • Ingelfinger JR, Zuo WM, Fon EA, et al. In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. J Clin Invest. 1990;85:417-423.
    • (1990) J Clin Invest , vol.85 , pp. 417-423
    • Ingelfinger, J.R.1    Zuo, W.M.2    Fon, E.A.3
  • 19
    • 84860147902 scopus 로고    scopus 로고
    • The establishment of a primary culture system of proximal tubule segments using specific markers from normal mouse kidneys
    • Kamiyama M, Garner MK, Farragut KM, et al. The establishment of a primary culture system of proximal tubule segments using specific markers from normal mouse kidneys. Int J Mol Sci. 2012;13:5098-5111.
    • (2012) Int J Mol Sci , vol.13 , pp. 5098-5111
    • Kamiyama, M.1    Garner, M.K.2    Farragut, K.M.3
  • 20
    • 84870254866 scopus 로고    scopus 로고
    • Divergent localizations of angiotensinogen mRNA and protein in proximal tubular segments of normal rat kidney
    • Kamiyama M, Farragut KM, Garner MK, et al. Divergent localizations of angiotensinogen mRNA and protein in proximal tubular segments of normal rat kidney. J Hypertens. 2012;30:2365-2372.
    • (2012) J Hypertens , vol.30 , pp. 2365-2372
    • Kamiyama, M.1    Farragut, K.M.2    Garner, M.K.3
  • 21
    • 0027163984 scopus 로고
    • Pcr localization of angiotensin II receptor and angiotensinogen mRNAs in rat kidney
    • Terada Y, Tomita K, Nonoguchi H, et al. Pcr localization of angiotensin II receptor and angiotensinogen mRNAs in rat kidney. Kidney Int. 1993;43:1251-1259.
    • (1993) Kidney Int , vol.43 , pp. 1251-1259
    • Terada, Y.1    Tomita, K.2    Nonoguchi, H.3
  • 22
    • 0020593549 scopus 로고
    • Immunocytochemical localization of angiotensinogen in rat liver and kidney
    • Richoux JP, Cordonnier JL, Bouhnik J, et al. Immunocytochemical localization of angiotensinogen in rat liver and kidney. Cell Tissue Res. 1983;233:439-451.
    • (1983) Cell Tissue Res , vol.233 , pp. 439-451
    • Richoux, J.P.1    Cordonnier, J.L.2    Bouhnik, J.3
  • 23
    • 0028035288 scopus 로고
    • Cellular and ultrastructural location of angiotensinogen in rat and sheep kidney
    • Darby IA, Congiu M, Fernley RT, et al. Cellular and ultrastructural location of angiotensinogen in rat and sheep kidney. Kidney Int. 1994;46:1557-1560.
    • (1994) Kidney Int , vol.46 , pp. 1557-1560
    • Darby, I.A.1    Congiu, M.2    Fernley, R.T.3
  • 24
    • 0029045305 scopus 로고
    • In situ hybridization and immunohistochemistry of renal angiotensinogen in neonatal and adult rat kidneys
    • Darby IA, Sernia C. In situ hybridization and immunohistochemistry of renal angiotensinogen in neonatal and adult rat kidneys. Cell Tissue Res. 1995;281:197-206.
    • (1995) Cell Tissue Res , vol.281 , pp. 197-206
    • Darby, I.A.1    Sernia, C.2
  • 25
    • 0035119735 scopus 로고    scopus 로고
    • Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension
    • Kobori H, Harrison-Bernard LM, Navar LG. Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension. J Am Soc Nephrol. 2001;12:431-439.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 431-439
    • Kobori, H.1    Harrison-Bernard, L.M.2    Navar, L.G.3
  • 26
    • 78650650377 scopus 로고    scopus 로고
    • Intrarenal renin angiotensin system revisited: Role of megalin-dependent endocytosis along the proximal nephron
    • Pohl M, Kaminski H, Castrop H, et al. Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron. J Biol Chem. 2010;285:41935-41946.
    • (2010) J Biol Chem , vol.285 , pp. 41935-41946
    • Pohl, M.1    Kaminski, H.2    Castrop, H.3
  • 27
    • 0022504015 scopus 로고
    • Changes in single nephron renin release are mediated by tubular fluid flow rate
    • Leyssac PP. Changes in single nephron renin release are mediated by tubular fluid flow rate. Kidney Int. 1986;30:332-339.
    • (1986) Kidney Int , vol.30 , pp. 332-339
    • Leyssac, P.P.1
  • 28
    • 0025869028 scopus 로고
    • Production of angiotensinogen and renin-like activity by rabbit proximal tubular cells in culture
    • Yanagawa N, Capparelli AW, Jo OD, et al. Production of angiotensinogen and renin-like activity by rabbit proximal tubular cells in culture. Kidney Int. 1991;39:938-941.
    • (1991) Kidney Int , vol.39 , pp. 938-941
    • Yanagawa, N.1    Capparelli, A.W.2    Jo, O.D.3
  • 29
    • 0029884275 scopus 로고    scopus 로고
    • Renin regulation in cultured proximal tubular cells
    • Henrich WL, McAllister EA, Eskue A, et al. Renin regulation in cultured proximal tubular cells. Hypertension. 1996;27:1337-1340.
    • (1996) Hypertension , vol.27 , pp. 1337-1340
    • Henrich, W.L.1    McAllister, E.A.2    Eskue, A.3
  • 30
    • 0027394577 scopus 로고
    • Renin expression in renal proximal tubule
    • Moe OW, Ujiie K, Star RA, et al. Renin expression in renal proximal tubule. J Clin Invest. 1993;91:774-779.
    • (1993) J Clin Invest , vol.91 , pp. 774-779
    • Moe, O.W.1    Ujiie, K.2    Star, R.A.3
  • 31
    • 0027241828 scopus 로고
    • Gene expression and tissue localization of the two isoforms of angiotensin i converting enzyme
    • Sibony M, Gasc JM, Soubrier F, et al. Gene expression and tissue localization of the two isoforms of angiotensin I converting enzyme. Hypertension. 1993;21:827-835.
    • (1993) Hypertension , vol.21 , pp. 827-835
    • Sibony, M.1    Gasc, J.M.2    Soubrier, F.3
  • 32
    • 0024271006 scopus 로고
    • Ultrastructural localization of angiotensin IYconverting enzyme (EC 3.4.15.1) and neutral metalloendopeptidase (EC 3.4.24.11) in the proximal tubule of the human kidney
    • Schulz WW, Hagler HK, Buja LM, et al. Ultrastructural localization of angiotensin IYconverting enzyme (EC 3.4.15.1) and neutral metalloendopeptidase (EC 3.4.24.11) in the proximal tubule of the human kidney. Lab Invest. 1988;59:789-797.
    • (1988) Lab Invest , vol.59 , pp. 789-797
    • Schulz, W.W.1    Hagler, H.K.2    Buja, L.M.3
  • 33
    • 17944389392 scopus 로고    scopus 로고
    • Local induction of angiotensin-converting enzyme in the kidney as a mechanism of progressive renal diseases
    • Vio CP, Jeanneret VA. Local induction of angiotensin-converting enzyme in the kidney as a mechanism of progressive renal diseases. Kidney Int Suppl. 2003;64:S57YS63.
    • (2003) Kidney Int Suppl , vol.64
    • Vio, C.P.1    Jeanneret, V.A.2
  • 34
    • 0030822547 scopus 로고    scopus 로고
    • Angiotensin IYconverting enzyme activity in tubular fluid along the rat nephron
    • Casarini DE, Boim MA, Stella RC, et al. Angiotensin IYconverting enzyme activity in tubular fluid along the rat nephron. Am J Physiol. 1997;272:F405YF409.
    • (1997) Am J Physiol , vol.272
    • Casarini, D.E.1    Boim, M.A.2    Stella, R.C.3
  • 35
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
    • Ye M, Wysocki J, William J, et al. Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol. 2006;17:3067-3075.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3
  • 36
    • 60549095157 scopus 로고    scopus 로고
    • Localization of ACE2 in the renal vasculature: Amplification by angiotensin II type 1 receptor blockade using telmisartan
    • Soler MJ, Ye M, Wysocki J, et al. Localization of ACE2 in the renal vasculature: amplification by angiotensin II type 1 receptor blockade using telmisartan. Am J Physiol Renal Physiol. 2009;296: F398YF405.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Soler, M.J.1    Ye, M.2    Wysocki, J.3
  • 37
    • 74049153435 scopus 로고    scopus 로고
    • Major role for ACE-independent intrarenal ANG II formation in type II diabetes
    • Park S, Bivona BJ, Kobori H, et al. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J physiol Renal Physiol. 2010;298:F37YF48.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Park, S.1    Bivona, B.J.2    Kobori, H.3
  • 38
    • 0032443625 scopus 로고    scopus 로고
    • Physiologic actions and molecular expression of the renin-angiotensin system in the diabetic rat
    • Anderson S. Physiologic actions and molecular expression of the renin-angiotensin system in the diabetic rat. Miner Electrolyte Metab. 1998;24:406-411.
    • (1998) Miner Electrolyte Metab , vol.24 , pp. 406-411
    • Anderson, S.1
  • 39
    • 0036012687 scopus 로고    scopus 로고
    • Renal AT1 receptor protein expression during the early stage of diabetes mellitus
    • Harrison-Bernard LM, Imig JD, Carmines PK. Renal AT1 receptor protein expression during the early stage of diabetes mellitus. Int J Exp Diabetes Res. 2002;3:97-108.
    • (2002) Int J Exp Diabetes Res , vol.3 , pp. 97-108
    • Harrison-Bernard, L.M.1    Imig, J.D.2    Carmines, P.K.3
  • 40
    • 0033672308 scopus 로고    scopus 로고
    • Early diabetes mellitus stimulates proximal tubule renin mrna expression in the rat
    • Zimpelmann J, Kumar D, Levine DZ, et al. Early diabetes mellitus stimulates proximal tubule renin mrna expression in the rat. Kidney Int. 2000;58:2320-2330.
    • (2000) Kidney Int , vol.58 , pp. 2320-2330
    • Zimpelmann, J.1    Kumar, D.2    Levine, D.Z.3
  • 41
    • 84860186531 scopus 로고    scopus 로고
    • Augmented intrarenal angiotensinogen mRNA expression parallels renal dysfunction in patients with type 2 diabetes [abstract]
    • Kamiyama M, Urusihara M, Morikawa T, et al. Augmented intrarenal angiotensinogen mRNA expression parallels renal dysfunction in patients with type 2 diabetes [abstract]. Hypertension. 2010;56:e135.
    • (2010) Hypertension , vol.56
    • Kamiyama, M.1    Urusihara, M.2    Morikawa, T.3
  • 42
    • 0035000020 scopus 로고    scopus 로고
    • Early streptozotocinYdiabetes mellitus downregulates rat kidney AT2 receptors
    • Wehbi GJ, Zimpelmann J, Carey RM, et al. Early streptozotocinYdiabetes mellitus downregulates rat kidney AT2 receptors. Am J Physiol Renal Physiol. 2001;280:F254YF265.
    • (2001) Am J Physiol Renal Physiol , vol.280
    • Wehbi, G.J.1    Zimpelmann, J.2    Carey, R.M.3
  • 43
    • 45849143635 scopus 로고    scopus 로고
    • The collecting duct is the major source of prorenin in diabetes
    • Kang JJ, Toma I, Sipos A, et al. The collecting duct is the major source of prorenin in diabetes. Hypertension. 2008;51:1597-1604.
    • (2008) Hypertension , vol.51 , pp. 1597-1604
    • Kang, J.J.1    Toma, I.2    Sipos, A.3
  • 44
    • 20544471721 scopus 로고    scopus 로고
    • Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats
    • Nagai Y, Yao L, Kobori H, et al. Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats. J Am Soc Nephrol. 2005;16:703-711.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 703-711
    • Nagai, Y.1    Yao, L.2    Kobori, H.3
  • 45
    • 84873624902 scopus 로고    scopus 로고
    • Delete in proof
    • Delete in proof.
  • 46
    • 33846479935 scopus 로고    scopus 로고
    • Intrarenal oxidative stress and augmented angiotensinogen are precedent to renal injury in zucker diabetic fatty rats
    • Suzaki Y, Ozawa Y, Kobori H. Intrarenal oxidative stress and augmented angiotensinogen are precedent to renal injury in zucker diabetic fatty rats. Int J Biol Sci. 2007;3:40-46.
    • (2007) Int J Biol Sci , vol.3 , pp. 40-46
    • Suzaki, Y.1    Ozawa, Y.2    Kobori, H.3
  • 47
    • 46749144204 scopus 로고    scopus 로고
    • Sequential activation of the reactive oxygen species/angiotensinogen/ renin-angiotensin system axis in renal injury of type 2 diabetic rats
    • Miyata K, Ohashi N, Suzaki Y, et al. Sequential activation of the reactive oxygen species/angiotensinogen/renin-angiotensin system axis in renal injury of type 2 diabetic rats. Clin Exp Pharmacol Physiol. 2008;35:922-927.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 922-927
    • Miyata, K.1    Ohashi, N.2    Suzaki, Y.3
  • 49
    • 0033034404 scopus 로고    scopus 로고
    • Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial
    • Hansson L, Lindholm LH, Niskanen L, et al. Effect of angiotensin- converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. Lancet. 1999;353:611-616.
    • (1999) Lancet , vol.353 , pp. 611-616
    • Hansson, L.1    Lindholm, L.H.2    Niskanen, L.3
  • 50
    • 0032511601 scopus 로고    scopus 로고
    • Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39
    • UK prospective diabetes study group
    • Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39. UK prospective diabetes study group. BMJ. 1998;317:713-720.
    • (1998) BMJ , vol.317 , pp. 713-720
  • 51
    • 33646415358 scopus 로고    scopus 로고
    • Endothelial dysfunction: How can one intervene at the beginning of the cardiovascular continuum?
    • Schmieder RE. Endothelial dysfunction: how can one intervene at the beginning of the cardiovascular continuum? J Hypertens Suppl. 2006;24:S31YS35.
    • (2006) J Hypertens Suppl , vol.24
    • Schmieder, R.E.1
  • 52
    • 0035922444 scopus 로고    scopus 로고
    • Irbesartan in patients with type 2 diabetes and microalbuminuria study G. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Brochner-Mortensen J, et al. Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study G. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med. 2001;345:870-878.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Brochner-Mortensen, J.3
  • 53
    • 7444221237 scopus 로고    scopus 로고
    • Bergamo nephrologic diabetes complications trial I. Preventing microalbuminuria in type 2 diabetes
    • Ruggenenti P, Fassi A, Ilieva AP, et al. Bergamo Nephrologic Diabetes Complications Trial I. Preventing microalbuminuria in type 2 diabetes. N Engl J Med. 2004;351:1941-1951.
    • (2004) N Engl J Med , vol.351 , pp. 1941-1951
    • Ruggenenti, P.1    Fassi, A.2    Ilieva, A.P.3
  • 54
    • 0035816018 scopus 로고    scopus 로고
    • African American study of kidney disease and hypertension study G. Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: A randomized controlled trial
    • Agodoa LY, Appel L, Bakris GL, et al. African American Study of Kidney Disease and Hypertension Study G. Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. JAMA. 2001;285:2719-2728.
    • (2001) JAMA , vol.285 , pp. 2719-2728
    • Agodoa, L.Y.1    Appel, L.2    Bakris, G.L.3
  • 55
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 56
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345: 851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 57
    • 7444237666 scopus 로고    scopus 로고
    • Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy
    • Barnett AH, Bain SC, Bouter P, et al. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med. 2004;351:1952-1961.
    • (2004) N Engl J Med , vol.351 , pp. 1952-1961
    • Barnett, A.H.1    Bain, S.C.2    Bouter, P.3
  • 58
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • Mann JF, Schmieder RE, McQueen M, et al. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial. Lancet. 2008;372:547-553.
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3
  • 59
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • Haller H, Ito S, Izzo JL, et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med. 2011;364:907-917.
    • (2011) N Engl J Med , vol.364 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo, J.L.3
  • 60
    • 79952436059 scopus 로고    scopus 로고
    • Preemptive olmesartan for the delay or prevention of microalbuminuria in diabetes
    • Ingelfinger Jr. Preemptive olmesartan for the delay or prevention of microalbuminuria in diabetes. N Engl J Med. 2011;364:970-971.
    • (2011) N Engl J Med , vol.364 , pp. 970-971
    • Ingelfinger, J.R.1
  • 61
    • 35848968871 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease in the united states
    • Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the united states. JAMA. 2007;298:2038-2047.
    • (2007) JAMA , vol.298 , pp. 2038-2047
    • Coresh, J.1    Selvin, E.2    Stevens, L.A.3
  • 62
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The diabetes control and complications trial research group
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The diabetes control and complications trial research group. N Engl J Med. 1993;329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 63
    • 0038323914 scopus 로고    scopus 로고
    • Regression of microalbuminuria in type 1 diabetes
    • Perkins BA, Ficociello LH, Silva KH, et al. Regression of microalbuminuria in type 1 diabetes. N Engl J Med. 2003;348:2285-2293.
    • (2003) N Engl J Med , vol.348 , pp. 2285-2293
    • Perkins, B.A.1    Ficociello, L.H.2    Silva, K.H.3
  • 64
    • 44349155406 scopus 로고    scopus 로고
    • Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics
    • Wolkow PP, Niewczas MA, Perkins B, et al. Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics. J Am Soc Nephrol. 2008;19:789-797.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 789-797
    • Wolkow, P.P.1    Niewczas, M.A.2    Perkins, B.3
  • 65
    • 85047676452 scopus 로고
    • Kinetics of the human renin and human substrate reaction
    • Gould AB, Green D. Kinetics of the human renin and human substrate reaction. Cardiovasc Res. 1971;5:86-89.
    • (1971) Cardiovasc Res , vol.5 , pp. 86-89
    • Gould, A.B.1    Green, D.2
  • 66
    • 0029979243 scopus 로고    scopus 로고
    • Mechanisms for inducible control of angiotensinogen gene transcription
    • Brasier AR, Li J. Mechanisms for inducible control of angiotensinogen gene transcription. Hypertension. 1996;27:465-475.
    • (1996) Hypertension , vol.27 , pp. 465-475
    • Brasier, A.R.1    Li, J.2
  • 67
    • 0030736087 scopus 로고    scopus 로고
    • The kidney androgen-regulated protein promoter confers renal proximal tubule cellYspecific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice
    • Ding Y, Davisson RL, Hardy DO, et al. The kidney androgen-regulated protein promoter confers renal proximal tubule cellYspecific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice. J Biol Chem. 1997;272:28142-28148.
    • (1997) J Biol Chem , vol.272 , pp. 28142-28148
    • Ding, Y.1    Davisson, R.L.2    Hardy, D.O.3
  • 68
    • 0026608537 scopus 로고
    • High blood pressure in transgenic mice carrying the rat angiotensinogen gene
    • Kimura S, Mullins JJ, Bunnemann B, et al. High blood pressure in transgenic mice carrying the rat angiotensinogen gene. EMBO J. 1992;11:821-827.
    • (1992) EMBO J , vol.11 , pp. 821-827
    • Kimura, S.1    Mullins, J.J.2    Bunnemann, B.3
  • 69
    • 0027190950 scopus 로고
    • Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes
    • Fukamizu A, Sugimura K, Takimoto E, et al. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J Biol Chem. 1993;268:11617-11621.
    • (1993) J Biol Chem , vol.268 , pp. 11617-11621
    • Fukamizu, A.1    Sugimura, K.2    Takimoto, E.3
  • 70
    • 17744417945 scopus 로고    scopus 로고
    • Angiotensinogen concentrations and renin clearance: Implications for blood pressure regulation
    • Bohlender J, Menard J, Ganten D, et al. Angiotensinogen concentrations and renin clearance: implications for blood pressure regulation. Hypertension. 2000;35:780-786.
    • (2000) Hypertension , vol.35 , pp. 780-786
    • Bohlender, J.1    Menard, J.2    Ganten, D.3
  • 71
    • 0031297091 scopus 로고    scopus 로고
    • Theodore cooper memorial lecture. A mouse view of hypertension
    • Smithies O. Theodore cooper memorial lecture. A mouse view of hypertension. Hypertension. 1997;30:1318-1324.
    • (1997) Hypertension , vol.30 , pp. 1318-1324
    • Smithies, O.1
  • 72
    • 0030049446 scopus 로고    scopus 로고
    • Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes
    • Merrill DC, Thompson MW, Carney CL, et al. Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest. 1996;97:1047-1055.
    • (1996) J Clin Invest , vol.97 , pp. 1047-1055
    • Merrill, D.C.1    Thompson, M.W.2    Carney, C.L.3
  • 73
    • 34548655306 scopus 로고    scopus 로고
    • Kidney-specific enhancement of Ang II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice
    • Kobori H, Ozawa Y, Satou R, et al. Kidney-specific enhancement of Ang II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice. Am J Physiol Renal Physiol. 2007;293: F938YF945.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Kobori, H.1    Ozawa, Y.2    Satou, R.3
  • 74
    • 33644853998 scopus 로고    scopus 로고
    • Ras blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney
    • Sachetelli S, Liu Q, Zhang SL, et al. Ras blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney. Kidney Int. 2006;69:1016-1023.
    • (2006) Kidney Int , vol.69 , pp. 1016-1023
    • Sachetelli, S.1    Liu, Q.2    Zhang, S.L.3
  • 75
    • 1942535146 scopus 로고    scopus 로고
    • Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule
    • Lavoie JL, Lake-Bruse KD, Sigmund CD. Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule. Am J Physiol Renal Physiol. 2004;286: F965YF971.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Lavoie, J.L.1    Lake-Bruse, K.D.2    Sigmund, C.D.3
  • 76
    • 0028354218 scopus 로고
    • Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice
    • Smithies O, Kim HS. Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice. Proc Natl Acad Sci U S A. 1994;91:3612-3615.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3612-3615
    • Smithies, O.1    Kim, H.S.2
  • 77
    • 0028944631 scopus 로고
    • Genetic control of blood pressure and the angiotensinogen locus
    • Kim HS, Krege JH, Kluckman KD, et al. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci U S A. 1995;92:2735-2739.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2735-2739
    • Kim, H.S.1    Krege, J.H.2    Kluckman, K.D.3
  • 78
    • 0030893575 scopus 로고    scopus 로고
    • A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
    • Inoue I, Nakajima T, Williams CS, et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest. 1997;99:1786-1797.
    • (1997) J Clin Invest , vol.99 , pp. 1786-1797
    • Inoue, I.1    Nakajima, T.2    Williams, C.S.3
  • 79
    • 0026669336 scopus 로고
    • Molecular basis of human hypertension: Role of angiotensinogen
    • Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992;71: 169-180.
    • (1992) Cell , vol.71 , pp. 169-180
    • Jeunemaitre, X.1    Soubrier, F.2    Kotelevtsev, Y.V.3
  • 80
    • 0010610371 scopus 로고    scopus 로고
    • Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene
    • Zhao YY, Zhou J, Narayanan CS, et al. Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene. Hypertension. 1999;33:108-115.
    • (1999) Hypertension , vol.33 , pp. 108-115
    • Zhao, Y.Y.1    Zhou, J.2    Narayanan, C.S.3
  • 81
    • 0030725820 scopus 로고    scopus 로고
    • Essential hypertension and 5′ upstream core promoter region of human angiotensinogen gene
    • Ishigami T, Umemura S, Tamura K, et al. Essential hypertension and 5′ upstream core promoter region of human angiotensinogen gene. Hypertension. 1997;30:1325-1330.
    • (1997) Hypertension , vol.30 , pp. 1325-1330
    • Ishigami, T.1    Umemura, S.2    Tamura, K.3
  • 82
    • 0026495960 scopus 로고
    • Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II
    • Schunkert H, Ingelfinger JR, Jacob H, et al. Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II. Am J Physiol. 1992;263:E863YE869.
    • (1992) Am J Physiol , vol.263
    • Schunkert, H.1    Ingelfinger, J.R.2    Jacob, H.3
  • 83
    • 2342527267 scopus 로고    scopus 로고
    • AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin IIYdependent hypertension
    • Kobori H, Prieto-Carrasquero MC, Ozawa Y, et al. AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin IIYdependent hypertension. Hypertension. 2004;43:1126-1132.
    • (2004) Hypertension , vol.43 , pp. 1126-1132
    • Kobori, H.1    Prieto-Carrasquero, M.C.2    Ozawa, Y.3
  • 84
    • 0037219640 scopus 로고    scopus 로고
    • Urinary angiotensinogen as an indicator of intrarenal angiotensin status in hypertension
    • Kobori H, Nishiyama A, Harrison-Bernard LM, et al. Urinary angiotensinogen as an indicator of intrarenal angiotensin status in hypertension. Hypertension. 2003;41:42-49.
    • (2003) Hypertension , vol.41 , pp. 42-49
    • Kobori, H.1    Nishiyama, A.2    Harrison-Bernard, L.M.3
  • 85
    • 0036158053 scopus 로고    scopus 로고
    • Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production
    • Kobori H, Harrison-Bernard LM, Navar LG. Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production. Kidney Int. 2002;61:579-585.
    • (2002) Kidney Int , vol.61 , pp. 579-585
    • Kobori, H.1    Harrison-Bernard, L.M.2    Navar, L.G.3
  • 86
    • 0035715157 scopus 로고    scopus 로고
    • Enhancement of angiotensinogen expression in angiotensin IIYdependent hypertension
    • Kobori H, Harrison-Bernard LM, Navar LG. Enhancement of angiotensinogen expression in angiotensin IIYdependent hypertension. Hypertension. 2001;37:1329-1335.
    • (2001) Hypertension , vol.37 , pp. 1329-1335
    • Kobori, H.1    Harrison-Bernard, L.M.2    Navar, L.G.3
  • 87
    • 1242340415 scopus 로고    scopus 로고
    • Effects of tempol on renal angiotensinogen production in Dahl saltYsensitive rats
    • Kobori H, Nishiyama A. Effects of tempol on renal angiotensinogen production in Dahl saltYsensitive rats. Biochem Biophys Res Commun. 2004;315:746-750.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 746-750
    • Kobori, H.1    Nishiyama, A.2
  • 88
    • 0037336667 scopus 로고    scopus 로고
    • Enhancement of intrarenal angiotensinogen in Dahl saltYsensitive rats on high salt diet
    • Kobori H, Nishiyama A, Abe Y, et al. Enhancement of intrarenal angiotensinogen in Dahl saltYsensitive rats on high salt diet. Hypertension. 2003;41:592-597.
    • (2003) Hypertension , vol.41 , pp. 592-597
    • Kobori, H.1    Nishiyama, A.2    Abe, Y.3
  • 89
    • 27744529624 scopus 로고    scopus 로고
    • Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats
    • Kobori H, Ozawa Y, Suzaki Y, et al. Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats. J Am Soc Nephrol. 2005;16:2073-2080.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2073-2080
    • Kobori, H.1    Ozawa, Y.2    Suzaki, Y.3
  • 90
    • 0027525040 scopus 로고
    • Renal renin-angiotensin system in diabetes: Functional, immunohistochemical, and molecular biological correlations
    • Anderson S, Jung FF, Ingelfinger Jr. Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am J Physiol. 1993;265:F477YF486.
    • (1993) Am J Physiol , vol.265
    • Anderson, S.1    Jung, F.F.2    Ingelfinger, J.R.3
  • 91
    • 18744376906 scopus 로고    scopus 로고
    • A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli
    • Singh R, Singh AK, Leehey DJ. A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli. Am J Physiol Renal Physiol. 2005;288:F1183YF1190.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Singh, R.1    Singh, A.K.2    Leehey, D.J.3
  • 92
    • 40849120442 scopus 로고    scopus 로고
    • Glomerular renin angiotensin system in streptozotocin diabetic and zucker diabetic fatty rats
    • Leehey DJ, Singh AK, Bast JP, et al. Glomerular renin angiotensin system in streptozotocin diabetic and zucker diabetic fatty rats. Transl Res. 2008;151:208-216.
    • (2008) Transl Res , vol.151 , pp. 208-216
    • Leehey, D.J.1    Singh, A.K.2    Bast, J.P.3
  • 93
    • 34248197665 scopus 로고    scopus 로고
    • Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients
    • Kobori H, Katsurada A, Ozawa Y, et al. Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients. Biochem Biophys Res Commun. 2007;358:156-163.
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 156-163
    • Kobori, H.1    Katsurada, A.2    Ozawa, Y.3
  • 94
    • 46949084854 scopus 로고    scopus 로고
    • Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy
    • Takamatsu M, Urushihara M, Kondo S, et al. Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. Pediatr Nephrol. 2008;23:1257-1267.
    • (2008) Pediatr Nephrol , vol.23 , pp. 1257-1267
    • Takamatsu, M.1    Urushihara, M.2    Kondo, S.3
  • 95
    • 33646109291 scopus 로고    scopus 로고
    • Young scholars award lecture: Intratubular angiotensinogen in hypertension and kidney diseases
    • Kobori H, Ozawa Y, Suzaki Y, et al. Young scholars award lecture: intratubular angiotensinogen in hypertension and kidney diseases. Am J Hypertens. 2006;19:541-550.
    • (2006) Am J Hypertens , vol.19 , pp. 541-550
    • Kobori, H.1    Ozawa, Y.2    Suzaki, Y.3
  • 96
    • 84865424264 scopus 로고    scopus 로고
    • Urinary angiotensinogen as a novel early biomarker of intrarenal renin-angiotensin system activation in experimental type 1 diabetes
    • Kamiyama M, Zsombok A, Kobori H. Urinary angiotensinogen as a novel early biomarker of intrarenal renin-angiotensin system activation in experimental type 1 diabetes. J Pharmacol Sci. 2012;119:314-323.
    • (2012) J Pharmacol Sci , vol.119 , pp. 314-323
    • Kamiyama, M.1    Zsombok, A.2    Kobori, H.3
  • 97
    • 84861096431 scopus 로고    scopus 로고
    • The link between the renin-angiotensin-aldosterone system and renal injury in obesity and the metabolic syndrome
    • Thethi T, Kamiyama M, Kobori H. The link between the renin-angiotensin- aldosterone system and renal injury in obesity and the metabolic syndrome. Cur Hyperten Rep. 2012;14:160-169.
    • (2012) Cur Hyperten Rep , vol.14 , pp. 160-169
    • Thethi, T.1    Kamiyama, M.2    Kobori, H.3
  • 99
    • 34248144931 scopus 로고    scopus 로고
    • Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease
    • Yamamoto T, Nakagawa T, Suzuki H, et al. Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease. J Am Soc Nephrol. 2007;18:1558-1565.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1558-1565
    • Yamamoto, T.1    Nakagawa, T.2    Suzuki, H.3
  • 100
    • 51449110587 scopus 로고    scopus 로고
    • Urinary angiotensinogen as a potential biomarker of severity of chronic kidney diseases
    • Kobori H, Ohashi N, Katsurada A, et al. Urinary angiotensinogen as a potential biomarker of severity of chronic kidney diseases. J Am Soc Hypertens. 2008;2:349-354.
    • (2008) J Am Soc Hypertens , vol.2 , pp. 349-354
    • Kobori, H.1    Ohashi, N.2    Katsurada, A.3
  • 101
    • 78650656643 scopus 로고    scopus 로고
    • Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy
    • Nishiyama A, Konishi Y, Ohashi N, et al. Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy. Nephrol Dial Transplant. 2011;26:170-177.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 170-177
    • Nishiyama, A.1    Konishi, Y.2    Ohashi, N.3
  • 102
    • 76549124438 scopus 로고    scopus 로고
    • Urinary angiotensinogen accurately reflects intrarenal renin-angiotensin system activity
    • Urushihara M, Kondo S, Kagami S, et al. Urinary angiotensinogen accurately reflects intrarenal renin-angiotensin system activity. Am J Nephrol. 2010;31:318-325.
    • (2010) Am J Nephrol , vol.31 , pp. 318-325
    • Urushihara, M.1    Kondo, S.2    Kagami, S.3
  • 103
    • 59849103597 scopus 로고    scopus 로고
    • Urinary angiotensinogen as a novel biomarker of the intrarenal renin-angiotensin system status in hypertensive patients
    • Kobori H, Alper AB, Shenava R, et al. Urinary angiotensinogen as a novel biomarker of the intrarenal renin-angiotensin system status in hypertensive patients. Hypertension. 2009;53:344-350.
    • (2009) Hypertension , vol.53 , pp. 344-350
    • Kobori, H.1    Alper, A.B.2    Shenava, R.3
  • 104
    • 77954386389 scopus 로고    scopus 로고
    • Urinary angiotensinogen is correlated with blood pressure in men (Bogalusa Heart Study)
    • Kobori H, Urushihara M, Xu JH, et al. Urinary angiotensinogen is correlated with blood pressure in men (Bogalusa Heart Study). J Hypertens. 2010;28:1422-1428.
    • (2010) J Hypertens , vol.28 , pp. 1422-1428
    • Kobori, H.1    Urushihara, M.2    Xu, J.H.3
  • 105
    • 67651205786 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockers reduce urinary angiotensinogen excretion and the levels of urinary markers of oxidative stress and inflammation in patients with type 2 diabetic nephropathy
    • Ogawa S, Kobori H, Ohashi N, et al. Angiotensin II type 1 receptor blockers reduce urinary angiotensinogen excretion and the levels of urinary markers of oxidative stress and inflammation in patients with type 2 diabetic nephropathy. Biomark Insights. 2009;4:97-102.
    • (2009) Biomark Insights , vol.4 , pp. 97-102
    • Ogawa, S.1    Kobori, H.2    Ohashi, N.3
  • 106
    • 73949108178 scopus 로고    scopus 로고
    • Increased urinary angiotensinogen is precedent to increased urinary albumin in patients with type 1 diabetes
    • Saito T, Urushihara M, Kotani Y, et al. Increased urinary angiotensinogen is precedent to increased urinary albumin in patients with type 1 diabetes. Am J Med Sci. 2009;338:478-480.
    • (2009) Am J Med Sci , vol.338 , pp. 478-480
    • Saito, T.1    Urushihara, M.2    Kotani, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.