Soluble thrombomodulin ameliorates ischemia-reperfusion injury of liver grafts by modulating the proinflammatory role of high-mobility group box 1

Tohoku Journal of Experimental Medicine

Volumn 239, Issue 4, 2016, Pages 315-323

  Kashiwadate, Toshiaki ^a   Miyagi, Shigehito ^a   Hara, Yasuyuki ^a   Akamatsu, Yorihiro ^a   Sekiguchi, Satoshi ^a   Kawagishi, Naoki ^a   Ohuchi, Noriaki ^a   Satomi, Susumu ^b  

^a TOHOKU UNIVERSITY HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

ART 123; Donation after cardiac death; HMGB1; Liver; Warm ischemia reperfusion injury

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; LACTATE DEHYDROGENASE; RECOMBINANT THROMBOMODULIN; TUMOR NECROSIS FACTOR; CYTOKINE; RECOMBINANT PROTEIN; THROMBOMODULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BILE SECRETION; CONTROLLED STUDY; DISSE SPACE; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENDOTHELIUM CELL; EX VIVO STUDY; HEART DEATH; ISOLATED LIVER; LIVER CELL DAMAGE; LIVER CIRCULATION; LIVER GRAFT; LIVER PERFUSION; MALE; MICROCIRCULATION; NONHUMAN; PROTEIN FUNCTION; RAT; REPERFUSION; REPERFUSION INJURY; SINGLE DRUG DOSE; WISTAR RAT; ANIMAL; BILE; BLOOD FLOW; INFLAMMATION; LIVER; LIVER FUNCTION TEST; LIVER TRANSPLANTATION; METABOLISM; PATHOLOGY; PERFUSION; SOLUBILITY; VASCULARIZATION;

ANIMALS; BILE; CYTOKINES; HMGB1 PROTEIN; INFLAMMATION; LIVER; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; MALE; PERFUSION; RATS, WISTAR; RECOMBINANT PROTEINS; REGIONAL BLOOD FLOW; REPERFUSION INJURY; SOLUBILITY; THROMBOMODULIN;

EID: 85006817633     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.239.315     Document Type: Article

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