-
1
-
-
0032726952
-
Perlecan is essential for cartilage and cephalic development.
-
Arikawa-Hirasawa, E., H. Watanabe, H. Takami, J. R. Hassell, and Y. Yamada. 1999. Perlecan is essential for cartilage and cephalic development. Nat. Genet. 23:354-358.
-
(1999)
Nat. Genet
, vol.23
, pp. 354-358
-
-
Arikawa-Hirasawa, E.1
Watanabe, H.2
Takami, H.3
Hassell, J.R.4
Yamada, Y.5
-
2
-
-
0035068499
-
Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene.
-
Arikawa-Hirasawa, E., W. R. Wilcox, A. H. Le, N. Silverman, P. Govindraj, J. R. Hassell, et al. 2001. Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene. Nat. Genet. 27:431-434.
-
(2001)
Nat. Genet
, vol.27
, pp. 431-434
-
-
Arikawa-Hirasawa, E.1
Wilcox, W.R.2
Le, A.H.3
Silverman, N.4
Govindraj, P.5
Hassell, J.R.6
-
3
-
-
18344383853
-
Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia
-
Arikawa-Hirasawa, E., A. H. Le, I. Nishino, I. Nonaka, N. C. Ho, C. A. Francomano, et al. 2002. Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia. Am. J. Hum. Genet. 70:1368-1375.
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 1368-1375
-
-
Arikawa-Hirasawa, E.1
Le, A.H.2
Nishino, I.3
Nonaka, I.4
Ho, N.C.5
Francomano, C.A.6
-
4
-
-
0037036852
-
Simvastatin preserves myocardial perfusion and coronary microvascular permeability in experimental hypercholesterolemia independent of lipid lowering
-
Bonetti, P. O., S. H. Wilson, M. Rodriguez-Porcel, D. R. Jr Holmes, L. O. Lerman, and A. Lerman. 2002. Simvastatin preserves myocardial perfusion and coronary microvascular permeability in experimental hypercholesterolemia independent of lipid lowering. J. Am. Coll. Cardiol. 40:546-554.
-
(2002)
J. Am. Coll. Cardiol
, vol.40
, pp. 546-554
-
-
Bonetti, P.O.1
Wilson, S.H.2
Rodriguez-Porcel, M.3
Holmes, D.R.4
Lerman, L.O.5
Lerman, A.6
-
5
-
-
0033025662
-
Vascular endothelial growth factor up-regulates nitric oxide synthase expression in endothelial cells.
-
Bouloumie, A., V. B. Schini-Kerth, and R. Busse. 1999. Vascular endothelial growth factor up-regulates nitric oxide synthase expression in endothelial cells. Cardiovasc. Res. 41:773-780.
-
(1999)
Cardiovasc. Res
, vol.41
, pp. 773-780
-
-
Bouloumie, A.1
Schini-Kerth, V.B.2
Busse, R.3
-
6
-
-
34250827108
-
Understanding eNOS for pharmacological modulation of endothelial function: A translational view
-
Braam, B., and M. C. Verhaar. 2007. Understanding eNOS for pharmacological modulation of endothelial function: a translational view. Curr. Pharm. Des. 13:1727-1740.
-
(2007)
Curr. Pharm. Des
, vol.13
, pp. 1727-1740
-
-
Braam, B.1
Verhaar, M.C.2
-
7
-
-
0034634281
-
Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress. Circ
-
Cai, H., and D. G. Harrison. 2000. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87:840-844.
-
(2000)
Res
, vol.87
, pp. 840-844
-
-
Cai, H.1
Harrison, D.G.2
-
8
-
-
0034076189
-
Mechanisms of angiogenesis and arteriogenesis.
-
Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6:389-395.
-
(2000)
Nat. Med
, vol.6
, pp. 389-395
-
-
Carmeliet, P.1
-
9
-
-
55049085236
-
Endothelial nitric oxide (NO) and its pathophysiologic regulation.
-
Chatterjee, A., S. M. Black, and J. D. Catravas. 2008. Endothelial nitric oxide (NO) and its pathophysiologic regulation. Vascul. Pharmacol. 49:134-140.
-
(2008)
Vascul. Pharmacol
, vol.49
, pp. 134-140
-
-
Chatterjee, A.1
Black, S.M.2
Catravas, J.D.3
-
10
-
-
0031029467
-
Characterization of recombinant perlecan domain I and its substitution by glycosaminoglycans and oligosaccharides
-
Costell, M., K. Mann, Y. Yamada, and R. Timpl. 1997. Characterization of recombinant perlecan domain I and its substitution by glycosaminoglycans and oligosaccharides. Eur. J. Biochem. 243:115-121.
-
(1997)
Eur. J. Biochem
, vol.243
, pp. 115-121
-
-
Costell, M.1
Mann, K.2
Yamada, Y.3
Timpl, R.4
-
11
-
-
0033615959
-
Perlecan maintains the integrity of cartilage and some basement membranes
-
Costell, M., E. Gustafsson, A. Aszodi, M. Morgelin, W. Bloch, E. Hunziker, et al. 1999. Perlecan maintains the integrity of cartilage and some basement membranes. J. Cell Biol. 147:1109-1122.
-
(1999)
J. Cell Biol
, vol.147
, pp. 1109-1122
-
-
Costell, M.1
Gustafsson, E.2
Aszodi, A.3
Morgelin, M.4
Bloch, W.5
Hunziker, E.6
-
12
-
-
0037178732
-
Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice.
-
Costell, M., R. Carmona, E. Gustafsson, M. Gonzalez-Iriarte, R. Fassler, and R. Munoz-Chapuli. 2002. Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice. Circ. Res. 91:158-164.
-
(2002)
Circ. Res
, vol.91
, pp. 158-164
-
-
Costell, M.1
Carmona, R.2
Gustafsson, E.3
Gonzalez-Iriarte, M.4
Fassler, R.5
Munoz-Chapuli, R.6
-
13
-
-
79960400832
-
Endorepellin, the angiostatic module of perlecan, interacts with both the alpha2beta1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): A dual receptor antagonism
-
Goyal, A., N. Pal, M. Concannon, M. Paul, M. Doran, C. Poluzzi, et al. 2011. Endorepellin, the angiostatic module of perlecan, interacts with both the alpha2beta1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism. J. Biol. Chem. 286:25947-25962.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 25947-25962
-
-
Goyal, A.1
Pal, N.2
Concannon, M.3
Paul, M.4
Doran, M.5
Poluzzi, C.6
-
14
-
-
33845914882
-
Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1
-
Hozumi, K., N. Suzuki, P. K. Nielsen, M. Nomizu, and Y. Yamada. 2006. Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1. J. Biol. Chem. 281:32929-32940.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 32929-32940
-
-
Hozumi, K.1
Suzuki, N.2
Nielsen, P.K.3
Nomizu, M.4
Yamada, Y.5
-
15
-
-
2542429461
-
Extracellular matrices of the avian ovarian follicle. Molecular characterization of chicken perlecan
-
Hummel, S., A. Osanger, T. M. Bajari, M. Balasubramani, W. Halfter, J. Nimpf, et al. 2004. Extracellular matrices of the avian ovarian follicle. Molecular characterization of chicken perlecan. J. Biol. Chem. 279:23486-23494.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 23486-23494
-
-
Hummel, S.1
Osanger, A.2
Bajari, T.M.3
Balasubramani, M.4
Halfter, W.5
Nimpf, J.6
-
16
-
-
0032887926
-
Inhibition of guanylate cyclase stimulation by NO and bovine arterial relaxation to peroxynitrite and H2O2
-
Iesaki, T., S. A. Gupte, P. M. Kaminski, and M. S. Wolin. 1999. Inhibition of guanylate cyclase stimulation by NO and bovine arterial relaxation to peroxynitrite and H2O2. Am. J. Physiol. 277:H978-H985.
-
(1999)
Am. J. Physiol
, vol.277
, pp. H978-H985
-
-
Iesaki, T.1
Gupte, S.A.2
Kaminski, P.M.3
Wolin, M.S.4
-
17
-
-
84860642696
-
Perlecan-deficient mutation impairs corneal epithelial structure.
-
Inomata, T., N. Ebihara, T. Funaki, A. Matsuda, Y. Watanabe, L. Ning, et al. 2012. Perlecan-deficient mutation impairs corneal epithelial structure. Invest. Ophthalmol. Vis. Sci. 53:1277-1284.
-
(2012)
Invest. Ophthalmol. Vis. Sci
, vol.53
, pp. 1277-1284
-
-
Inomata, T.1
Ebihara, N.2
Funaki, T.3
Matsuda, A.4
Watanabe, Y.5
Ning, L.6
-
18
-
-
23144436642
-
Basement membrane proteoglycans: From cellar to ceiling
-
Iozzo, R. V. 2005. Basement membrane proteoglycans: from cellar to ceiling. Nat. Rev. Mol. Cell Biol. 6:646-656.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 646-656
-
-
Iozzo, R.V.1
-
19
-
-
0034904186
-
Heparan sulfate proteoglycans: Heavy hitters in the angiogenesis arena
-
Iozzo, R. V., and J. D. San Antonio. 2001. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena. J. Clin. Invest. 108:349-355.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 349-355
-
-
Iozzo, R.V.1
San Antonio, J.D.2
-
20
-
-
84860265668
-
Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation
-
Ishijima, M., N. Suzuki, K. Hozumi, T. Matsunobu, K. Kosaki, H. Kaneko, et al. 2012. Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 31:234-245.
-
(2012)
Matrix Biol
, vol.31
, pp. 234-245
-
-
Ishijima, M.1
Suzuki, N.2
Hozumi, K.3
Matsunobu, T.4
Kosaki, K.5
Kaneko, H.6
-
22
-
-
84876843059
-
Synovial perlecan is required for osteophyte formation in knee osteoarthritis
-
Kaneko, H., M. Ishijima, I. Futami, N. Tomikawa-Ichikawa, K. Kosaki, R. Sadatsuki, et al. 2013. Synovial perlecan is required for osteophyte formation in knee osteoarthritis. Matrix Biol. 32:178-187.
-
(2013)
Matrix Biol
, vol.32
, pp. 178-187
-
-
Kaneko, H.1
Ishijima, M.2
Futami, I.3
Tomikawa-Ichikawa, N.4
Kosaki, K.5
Sadatsuki, R.6
-
23
-
-
34748926972
-
Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu
-
Kerever, A., J. Schnack, D. Vellinga, N. Ichikawa, C. Moon, E. Arikawa-Hirasawa, et al. 2007. Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu. Stem Cells 25:2146-2157.
-
(2007)
Stem Cells
, vol.25
, pp. 2146-2157
-
-
Kerever, A.1
Schnack, J.2
Vellinga, D.3
Ichikawa, N.4
Moon, C.5
Arikawa-Hirasawa, E.6
-
24
-
-
0032584177
-
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
-
Laufs, U., V. La Fata, J. Plutzky, and J. K. Liao. 1998. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97:1129-1135.
-
(1998)
Circulation
, vol.97
, pp. 1129-1135
-
-
Laufs, U.1
La Fata, V.2
Plutzky, J.3
Liao, J.K.4
-
25
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
-
McQuillan, L. P., G. K. Leung, P. A. Marsden, S. K. Kostyk, and S. Kourembanas. 1994. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267:H1921-H1927.
-
(1994)
Am. J. Physiol
, vol.267
, pp. H1921-H1927
-
-
McQuillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
Kostyk, S.K.4
Kourembanas, S.5
-
26
-
-
0033662239
-
Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (Chondrodystrophic myotonia).
-
Nicole, S., C. S. Davoine, H. Topaloglu, L. Cattolico, D. Barral, P. Beighton, et al. 2000. Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia). Nat. Genet. 26:480-483.
-
(2000)
Nat. Genet
, vol.26
, pp. 480-483
-
-
Nicole, S.1
Davoine, C.S.2
Topaloglu, H.3
Cattolico, L.4
Barral, D.5
Beighton, P.6
-
27
-
-
0026497997
-
Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase
-
Nishida, K., D. G. Harrison, J. P. Navas, A. A. Fisher, S. P. Dockery, M. Uematsu, et al. 1992. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J. Clin. Invest. 90:2092-2096.
-
(1992)
J. Clin. Invest
, vol.90
, pp. 2092-2096
-
-
Nishida, K.1
Harrison, D.G.2
Navas, J.P.3
Fisher, A.A.4
Dockery, S.P.5
Uematsu, M.6
-
28
-
-
0026317977
-
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
-
Noonan, D. M., A. Fulle, P. Valente, S. Cai, E. Horigan, M. Sasaki, et al. 1991. The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. J. Biol. Chem. 266:22939-22947.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 22939-22947
-
-
Noonan, D.M.1
Fulle, A.2
Valente, P.3
Cai, S.4
Horigan, E.5
Sasaki, M.6
-
29
-
-
0033566680
-
Molecular control of nitric oxide synthases in the cardiovascular system.
-
Papapetropoulos, A., R. D. Rudic, and W. C. Sessa. 1999. Molecular control of nitric oxide synthases in the cardiovascular system. Cardiovasc. Res. 43:509-520.
-
(1999)
Cardiovasc. Res
, vol.43
, pp. 509-520
-
-
Papapetropoulos, A.1
Rudic, R.D.2
Sessa, W.C.3
-
30
-
-
0034529045
-
Lipoprotein modulation of subendothelial heparan sulfate proteoglycans (Perlecan) and atherogenicity.
-
Pillarisetti, S. 2000. Lipoprotein modulation of subendothelial heparan sulfate proteoglycans (perlecan) and atherogenicity. Trends Cardiovasc. Med. 10:60-65.
-
(2000)
Trends Cardiovasc. Med
, vol.10
, pp. 60-65
-
-
Pillarisetti, S.1
-
31
-
-
4043063680
-
The role of perlecan in arterial injury and angiogenesis.
-
Segev, A., N. Nili, and B. H. Strauss. 2004. The role of perlecan in arterial injury and angiogenesis. Cardiovasc. Res. 63:603-610.
-
(2004)
Cardiovasc. Res
, vol.63
, pp. 603-610
-
-
Segev, A.1
Nili, N.2
Strauss, B.H.3
-
32
-
-
0028118896
-
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.
-
Sessa, W. C., K. Pritchard, N. Seyedi, J. Wang, and T. H. Hintze. 1994. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res. 74:349-353.
-
(1994)
Circ. Res
, vol.74
, pp. 349-353
-
-
Sessa, W.C.1
Pritchard, K.2
Seyedi, N.3
Wang, J.4
Hintze, T.H.5
-
33
-
-
33750906742
-
Spectrum of HSPG2 (Perlecan) mutations in patients with Schwartz-Jampel syndrome.
-
Stum, M., C. S. Davoine, S. Vicart, L. Guillot-Noel, H. Topaloglu, F. J. Carod-Artal, et al. 2006. Spectrum of HSPG2 (Perlecan) mutations in patients with Schwartz-Jampel syndrome. Hum. Mutat. 27:1082-1091.
-
(2006)
Hum. Mutat
, vol.27
, pp. 1082-1091
-
-
Stum, M.1
Davoine, C.S.2
Vicart, S.3
Guillot-Noel, L.4
Topaloglu, H.5
Carod-Artal, F.J.6
-
34
-
-
56549092746
-
Deletion of the Fc receptors gamma chain preserves endothelial function affected by hypercholesterolaemia in mice fed on a high-fat diet.
-
Sumiyoshi, K., H. Mokuno, T. Iesaki, K. Shimada, T. Miyazaki, A. Kume, et al. 2008. Deletion of the Fc receptors gamma chain preserves endothelial function affected by hypercholesterolaemia in mice fed on a high-fat diet. Cardiovasc. Res. 80:463-470.
-
(2008)
Cardiovasc. Res
, vol.80
, pp. 463-470
-
-
Sumiyoshi, K.1
Mokuno, H.2
Iesaki, T.3
Shimada, K.4
Miyazaki, T.5
Kume, A.6
-
35
-
-
48049100574
-
Heparan sulfate in perlecan promotes mouse atherosclerosis: Roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.
-
Tran-Lundmark, K., P. K. Tran, G. Paulsson-Berne, V. Friden, R. Soininen, K. Tryggvason, et al. 2008. Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ. Res. 103:43-52.
-
(2008)
Circ. Res
, vol.103
, pp. 43-52
-
-
Tran-Lundmark, K.1
Tran, P.K.2
Paulsson-Berne, G.3
Friden, V.4
Soininen, R.5
Tryggvason, K.6
-
36
-
-
0033545218
-
Role of CDMP-1 in skeletal morphogenesis: Promotion of mesenchymal cell recruitment and chondrocyte differentiation
-
Tsumaki, N., K. Tanaka, E. Arikawa-Hirasawa, T. Nakase, T. Kimura, J. T. Thomas, et al. 1999. Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J. Cell Biol. 144:161-173.
-
(1999)
J. Cell Biol
, vol.144
, pp. 161-173
-
-
Tsumaki, N.1
Tanaka, K.2
Arikawa-Hirasawa, E.3
Nakase, T.4
Kimura, T.5
Thomas, J.T.6
-
37
-
-
65649110801
-
Endothelial dysfunction: The first step toward coronary arteriosclerosis
-
Vanhoutte, P. M. 2009. Endothelial dysfunction: the first step toward coronary arteriosclerosis. Circ. J. 73:595-601.
-
(2009)
Circ. J
, vol.73
, pp. 595-601
-
-
Vanhoutte, P.M.1
-
38
-
-
14244251162
-
Atherosclerosis in perlecan heterozygous mice
-
Vikramadithyan, R. K., Y. Kako, G. Chen, Y. Hu, E. Arikawa-Hirasawa, Y. Yamada, et al. 2004. Atherosclerosis in perlecan heterozygous mice. J. Lipid Res. 45:1806-1812.
-
(2004)
J. Lipid Res
, vol.45
, pp. 1806-1812
-
-
Vikramadithyan, R.K.1
Kako, Y.2
Chen, G.3
Hu, Y.4
Arikawa-Hirasawa, E.5
Yamada, Y.6
-
39
-
-
77956475154
-
Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition
-
Xu, Z., N. Ichikawa, K. Kosaki, Y. Yamada, T. Sasaki, L. Y. Sakai, et al. 2010. Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition. Matrix Biol. 29:461-470.
-
(2010)
Matrix Biol
, vol.29
, pp. 461-470
-
-
Xu, Z.1
Ichikawa, N.2
Kosaki, K.3
Yamada, Y.4
Sasaki, T.5
Sakai, L.Y.6
-
40
-
-
0029060686
-
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine
-
Zembowicz, A., J. L. Tang, and K. K. Wu. 1995. Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine. J. Biol. Chem. 270:17006-17010.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 17006-17010
-
-
Zembowicz, A.1
Tang, J.L.2
Wu, K.K.3
-
41
-
-
67649367545
-
Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis
-
Zoeller, J. J., J. M. Whitelock, and R. V. Iozzo. 2009. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. Matrix Biol. 28:284-291.
-
(2009)
Matrix Biol
, vol.28
, pp. 284-291
-
-
Zoeller, J.J.1
Whitelock, J.M.2
Iozzo, R.V.3
|