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Volumn 42, Issue 4, 2015, Pages 391-405

Systematic review: factors associated with relapse of inflammatory bowel disease after discontinuation of anti-TNF therapy

Author keywords

[No Author keywords available]

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; ADALIMUMAB; ANTIBODY; C REACTIVE PROTEIN; CALGRANULIN; CERTOLIZUMAB PEGOL; HEMOGLOBIN; INFLIXIMAB; METHOTREXATE; SACCHAROMYCES CEREVISIAE ANTIBODY; UNCLASSIFIED DRUG;

EID: 85006386593     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/apt.13276     Document Type: Review
Times cited : (93)

References (98)
  • 1
    • 79953801792 scopus 로고    scopus 로고
    • Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis
    • quiz 660
    • Ford AC, Sandborn WJ, Khan KJ, Hanauer SB, Talley NJ, Moayyedi P. Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 2011; 106: 644–59, quiz 660.
    • (2011) Am J Gastroenterol , vol.106 , pp. 644-659
    • Ford, A.C.1    Sandborn, W.J.2    Khan, K.J.3    Hanauer, S.B.4    Talley, N.J.5    Moayyedi, P.6
  • 3
    • 70350172248 scopus 로고    scopus 로고
    • Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease
    • Schnitzler F, Fidder H, Ferrante M, et al. Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease. Inflamm Bowel Dis 2009; 15: 1295–301.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1295-1301
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 4
    • 75449114677 scopus 로고    scopus 로고
    • Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease
    • quiz e410–461
    • Baert F, Moortgat L, Van Assche G, et al. Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease. Gastroenterology 2010; 138: 463–8; quiz e410–461.
    • (2010) Gastroenterology , vol.138 , pp. 463-468
    • Baert, F.1    Moortgat, L.2    Van, A.G.3
  • 5
    • 17144388945 scopus 로고    scopus 로고
    • Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease
    • Lichtenstein GR, Yan S, Bala M, Blank M, Sands BE. Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease. Gastroenterology 2005; 128: 862–9.
    • (2005) Gastroenterology , vol.128 , pp. 862-869
    • Lichtenstein, G.R.1    Yan, S.2    Bala, M.3    Blank, M.4    Sands, B.E.5
  • 6
    • 84881187537 scopus 로고    scopus 로고
    • Opportunistic infections with anti-tumor necrosis factor-alpha therapy in inflammatory bowel disease: meta-analysis of randomized controlled trials
    • Ford AC, Peyrin-Biroulet L. Opportunistic infections with anti-tumor necrosis factor-alpha therapy in inflammatory bowel disease: meta-analysis of randomized controlled trials. Am J Gastroenterol 2013; 108: 1268–76.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1268-1276
    • Ford, A.C.1    Peyrin-Biroulet, L.2
  • 7
    • 84890117256 scopus 로고    scopus 로고
    • Extra-intestinal malignancies in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (III)
    • Magro F, Peyrin-Biroulet L, Sokol H, et al. Extra-intestinal malignancies in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (III). J Crohns Colitis 2014; 8: 31–44.
    • (2014) J Crohns Colitis , vol.8 , pp. 31-44
    • Magro, F.1    Peyrin-Biroulet, L.2    Sokol, H.3
  • 8
    • 83555174451 scopus 로고    scopus 로고
    • Stopping immunomodulators and biologics in inflammatory bowel disease patients in remission
    • Clarke K, Regueiro M. Stopping immunomodulators and biologics in inflammatory bowel disease patients in remission. Inflamm Bowel Dis 2012; 18: 174–9.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 174-179
    • Clarke, K.1    Regueiro, M.2
  • 9
    • 44649154404 scopus 로고    scopus 로고
    • Health-economic analysis: cost-effectiveness of scheduled maintenance treatment with infliximab for Crohn's disease–modelling outcomes in active luminal and fistulizing disease in adults
    • Lindsay J, Punekar YS, Morris J, Chung-Faye G. Health-economic analysis: cost-effectiveness of scheduled maintenance treatment with infliximab for Crohn's disease–modelling outcomes in active luminal and fistulizing disease in adults. Aliment Pharmacol Ther 2008; 28: 76–87.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 76-87
    • Lindsay, J.1    Punekar, Y.S.2    Morris, J.3    Chung-Faye, G.4
  • 10
    • 84859590148 scopus 로고    scopus 로고
    • Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study
    • Steenholdt C, Molazahi A, Ainsworth MA, Brynskov J, Ostergaard Thomsen O, Seidelin JB. Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study. Scand J Gastroenterol 2012; 47: 518–27.
    • (2012) Scand J Gastroenterol , vol.47 , pp. 518-527
    • Steenholdt, C.1    Molazahi, A.2    Ainsworth, M.A.3    Brynskov, J.4    Ostergaard Thomsen, O.5    Seidelin, J.B.6
  • 11
    • 77950843556 scopus 로고    scopus 로고
    • Anti-TNF and Crohn's disease: when should we stop?
    • Louis E, Belaiche J, Reenaers C. Anti-TNF and Crohn's disease: when should we stop? Curr Drug Targets 2010; 11: 148–51.
    • (2010) Curr Drug Targets , vol.11 , pp. 148-151
    • Louis, E.1    Belaiche, J.2    Reenaers, C.3
  • 12
    • 85052033168 scopus 로고    scopus 로고
    • Risk of relapse after anti-TNF discontinuation in inflammatory bowel disease: a meta-analysis (abstract)
    • Gisbert JP, Marín AC, Chaparro M. Risk of relapse after anti-TNF discontinuation in inflammatory bowel disease: a meta-analysis (abstract). J Crohns Colitis 2015; 9(Suppl.1): S315.
    • (2015) J Crohns Colitis , vol.9 , pp. S315
    • Gisbert, J.P.1    Marín, A.C.2    Chaparro, M.3
  • 13
  • 15
    • 84940774920 scopus 로고    scopus 로고
    • Outcome of elective withdrawal of anti-tumour necrosis factor-alpha therapy in patients with Crohn's disease in established remission
    • [Epub ahead of print]
    • Brooks AJ, Sebastian S, Cross SS, et al. Outcome of elective withdrawal of anti-tumour necrosis factor-alpha therapy in patients with Crohn's disease in established remission. J Crohns Colitis  2015; pii: jjv000. [Epub ahead of print]
    • (2015) J Crohns Colitis
    • Brooks, A.J.1    Sebastian, S.2    Cross, S.S.3
  • 16
    • 48349083342 scopus 로고    scopus 로고
    • Combined therapy with infliximab and seton drainage for perianal fistulizing Crohn's disease with anal endosonographic monitoring: a single-centre experience
    • Guidi L, Ratto C, Semeraro S, et al. Combined therapy with infliximab and seton drainage for perianal fistulizing Crohn's disease with anal endosonographic monitoring: a single-centre experience. Tech Coloproctol 2008; 12: 111–7.
    • (2008) Tech Coloproctol , vol.12 , pp. 111-117
    • Guidi, L.1    Ratto, C.2    Semeraro, S.3
  • 17
    • 28844467220 scopus 로고    scopus 로고
    • Clinical evolution of luminal and perianal Crohn's disease after inducing remission with infliximab: how long should patients be treated?
    • Domenech E, Hinojosa J, Nos P, et al. Clinical evolution of luminal and perianal Crohn's disease after inducing remission with infliximab: how long should patients be treated? Aliment Pharmacol Ther 2005; 22: 1107–13.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 1107-1113
    • Domenech, E.1    Hinojosa, J.2    Nos, P.3
  • 18
    • 43049173662 scopus 로고    scopus 로고
    • 12-month follow-up after successful infliximab therapy in pediatric Crohn disease
    • Wynands J, Belbouab R, Candon S, et al. 12-month follow-up after successful infliximab therapy in pediatric Crohn disease. J Pediatr Gastroenterol Nutr 2008; 46: 293–8.
    • (2008) J Pediatr Gastroenterol Nutr , vol.46 , pp. 293-298
    • Wynands, J.1    Belbouab, R.2    Candon, S.3
  • 19
    • 84952900823 scopus 로고    scopus 로고
    • Reassessment of Crohn's disease treated with at least 12 months of anti-TNF therapy: how likely is treatment withdrawal?
    • Dart RJ, Griffin N, Taylor K, et al. Reassessment of Crohn's disease treated with at least 12 months of anti-TNF therapy: how likely is treatment withdrawal? Frontline Gastroenterol 2014; 5: 176–82.
    • (2014) Frontline Gastroenterol , vol.5 , pp. 176-182
    • Dart, R.J.1    Griffin, N.2    Taylor, K.3
  • 20
    • 83955162272 scopus 로고    scopus 로고
    • Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped
    • quiz e31
    • Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. Gastroenterology 2012; 142: 63–70 e65; quiz e31.
    • (2012) Gastroenterology , vol.142 , pp. 63-70
    • Louis, E.1    Mary, J.Y.2    Vernier-Massouille, G.3
  • 21
    • 84867758755 scopus 로고    scopus 로고
    • Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation
    • Lu C, Waugh A, Bailey RJ, et al. Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation. World J Gastroenterol 2012; 18: 5058–64.
    • (2012) World J Gastroenterol , vol.18 , pp. 5058-5064
    • Lu, C.1    Waugh, A.2    Bailey, R.J.3
  • 22
    • 84872689289 scopus 로고    scopus 로고
    • Predictors of relapse in patients with Crohn's disease in remission after 1 year of biological therapy
    • Molnar T, Lakatos PL, Farkas K, et al. Predictors of relapse in patients with Crohn's disease in remission after 1 year of biological therapy. Aliment Pharmacol Ther 2013; 37: 225–33.
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 225-233
    • Molnar, T.1    Lakatos, P.L.2    Farkas, K.3
  • 23
    • 84902152021 scopus 로고    scopus 로고
    • Outcome after discontinuation of TNFalpha-blocking therapy in patients with inflammatory bowel disease in deep remission
    • Molander P, Farkkila M, Salminen K, et al. Outcome after discontinuation of TNFalpha-blocking therapy in patients with inflammatory bowel disease in deep remission. Inflamm Bowel Dis 2014; 20: 1021–8.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1021-1028
    • Molander, P.1    Farkkila, M.2    Salminen, K.3
  • 25
    • 34948830720 scopus 로고    scopus 로고
    • Maintenance of remission with infliximab in inflammatory bowel disease: efficacy and safety long-term follow-up
    • Caviglia R, Ribolsi M, Rizzi M, Emerenziani S, Annunziata M, Cicala M. Maintenance of remission with infliximab in inflammatory bowel disease: efficacy and safety long-term follow-up. World J Gastroenterol 2007; 13: 5238–44.
    • (2007) World J Gastroenterol , vol.13 , pp. 5238-5244
    • Caviglia, R.1    Ribolsi, M.2    Rizzi, M.3    Emerenziani, S.4    Annunziata, M.5    Cicala, M.6
  • 26
    • 84990219850 scopus 로고    scopus 로고
    • Factors influencing recurrence following suspension of biological treatment. Importance of mucosal healing
    • Ciria V, Silva P, Leo E, et al. Factors influencing recurrence following suspension of biological treatment. Importance of mucosal healing. J Crohns Colitis 2014; 8(Suppl.1): P487.
    • (2014) J Crohns Colitis , vol.8 , pp. P487
    • Ciria, V.1    Silva, P.2    Leo, E.3
  • 27
    • 84904765603 scopus 로고    scopus 로고
    • Infliximab as a bridge to remission maintained by antimetabolite therapy in Crohn's disease: a retrospective study
    • Chauvin A, Le Thuaut A, Belhassan M, et al. Infliximab as a bridge to remission maintained by antimetabolite therapy in Crohn's disease: a retrospective study. Dig Liver Dis 2014; 46: 695–700.
    • (2014) Dig Liver Dis , vol.46 , pp. 695-700
    • Chauvin, A.1    Le Thuaut, A.2    Belhassan, M.3
  • 28
    • 85006428970 scopus 로고    scopus 로고
    • Outcome of treatment with biological agents in Crohn's disease: 117 patients in 5 years from a tertiary referral center
    • Ramos L, Hernandez A, Carrillo M, Alonso I, Hernandez N, Quintero E. Outcome of treatment with biological agents in Crohn's disease: 117 patients in 5 years from a tertiary referral center. J Crohns Colitis 2014; 8(Suppl. 1): P398.
    • (2014) J Crohns Colitis , vol.8 , pp. P398
    • Ramos, L.1    Hernandez, A.2    Carrillo, M.3    Alonso, I.4    Hernandez, N.5    Quintero, E.6
  • 29
    • 84952943334 scopus 로고    scopus 로고
    • Withdrawal of infliximab (IFX) after achieving remission: outcome in a cohort of inflammatory bowel disease (IBD) patients
    • Luppino I, Spagnuolo R, Marasco R, et al. Withdrawal of infliximab (IFX) after achieving remission: outcome in a cohort of inflammatory bowel disease (IBD) patients. Dig Liver Dis 2013; 45S: S100–1.
    • (2013) Dig Liver Dis , vol.45S , pp. S100-S101
    • Luppino, I.1    Spagnuolo, R.2    Marasco, R.3
  • 30
    • 84990194562 scopus 로고    scopus 로고
    • Outcome of infliximab discontinuation in IBD patients and therapy rechallenging in relapsers: single centre preliminary data
    • Marino M, Zucchi E, Fabbro M, et al. Outcome of infliximab discontinuation in IBD patients and therapy rechallenging in relapsers: single centre preliminary data. J Crohns Colitis 2014; 8(Suppl. 1): P401.
    • (2014) J Crohns Colitis , vol.8 , pp. P401
    • Marino, M.1    Zucchi, E.2    Fabbro, M.3
  • 31
    • 80052775138 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: a population-based study
    • Crombe V, Salleron J, Savoye G, et al. Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: a population-based study. Inflamm Bowel Dis 2011; 17: 2144–52.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 2144-2152
    • Crombe, V.1    Salleron, J.2    Savoye, G.3
  • 32
    • 85006428979 scopus 로고    scopus 로고
    • Normalized wall thickness at MRE predicts clinical remission in Crohn's disease after infliximab discontinuation: a 5 years follow-up
    • Annunziata ML, Papparella LG, Sansoni I, Balestrieri P, Cicala M. Normalized wall thickness at MRE predicts clinical remission in Crohn's disease after infliximab discontinuation: a 5 years follow-up. J Crohns Colitis 2014; 8(Suppl. 1): P402.
    • (2014) J Crohns Colitis , vol.8 , pp. P402
    • Annunziata, M.L.1    Papparella, L.G.2    Sansoni, I.3    Balestrieri, P.4    Cicala, M.5
  • 33
    • 78649465120 scopus 로고    scopus 로고
    • Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort
    • Waugh AW, Garg S, Matic K, et al. Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort. Aliment Pharmacol Ther 2010; 32: 1129–34.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1129-1134
    • Waugh, A.W.1    Garg, S.2    Matic, K.3
  • 34
    • 84952886525 scopus 로고    scopus 로고
    • Long term efficacy of infliximab in inflammatory bowel disease at a single tertiary center
    • Nuti F, Conte F, Cavallari N, et al. Long term efficacy of infliximab in inflammatory bowel disease at a single tertiary center. Dig Liver Dis 2010; 42: S326–7.
    • (2010) Dig Liver Dis , vol.42 , pp. S326-S327
    • Nuti, F.1    Conte, F.2    Cavallari, N.3
  • 35
    • 84892145631 scopus 로고    scopus 로고
    • Predictors of relapse in patients with ulcerative colitis in remission after one-year of infliximab therapy
    • Farkas K, Lakatos PL, Nagy F, et al. Predictors of relapse in patients with ulcerative colitis in remission after one-year of infliximab therapy. Scand J Gastroenterol 2013; 48: 1394–8.
    • (2013) Scand J Gastroenterol , vol.48 , pp. 1394-1398
    • Farkas, K.1    Lakatos, P.L.2    Nagy, F.3
  • 36
    • 84886953800 scopus 로고    scopus 로고
    • Long-term scheduled therapy with infliximab in inflammatory bowel disease: a single-centre observational study
    • Armuzzi A, Marzo M, Felice C, et al. Long-term scheduled therapy with infliximab in inflammatory bowel disease: a single-centre observational study. Gastroenterology 2010; 238(Suppl. 1): S-691.
    • (2010) Gastroenterology , vol.238 , pp. 691
    • Armuzzi, A.1    Marzo, M.2    Felice, C.3
  • 37
    • 84952926006 scopus 로고    scopus 로고
    • Mucosal healing in patients with ulcerative colitis treated with infliximab. What happens after treatment is discontinued?
    • Muñoz C, Bravo MT, deOrtiz Zárate J, et al. Mucosal healing in patients with ulcerative colitis treated with infliximab. What happens after treatment is discontinued? J Crohns Colitis 2014; 8(Suppl. 1): P405.
    • (2014) J Crohns Colitis , vol.8 , pp. P405
    • Muñoz, C.1    Bravo, M.T.2    de Ortiz, Z.J.3
  • 38
    • 84908178922 scopus 로고    scopus 로고
    • Mucosal healing did not predict sustained clinical remission in patients with IBD after discontinuation of one-year infliximab therapy
    • Dai C, Liu WX, Jiang M, Sun MJ. Mucosal healing did not predict sustained clinical remission in patients with IBD after discontinuation of one-year infliximab therapy. PLoS ONE 2014; 9: e110797.
    • (2014) PLoS ONE , vol.9
    • Dai, C.1    Liu, W.X.2    Jiang, M.3    Sun, M.J.4
  • 39
    • 84930377782 scopus 로고    scopus 로고
    • Long-term outcome of patients with Crohn's Disease who discontinued infliximab therapy upon clinical remission
    • Papamichael K, Vande Casteele N, Gils A, et al. Long-term outcome of patients with Crohn's Disease who discontinued infliximab therapy upon clinical remission. Clin Gastroenterol Hepatol 2015; 13: 1103–10.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 1103-1110
    • Papamichael, K.1    Vande Casteele, N.2    Gils, A.3
  • 40
    • 84904425206 scopus 로고    scopus 로고
    • Review article: why, when and how to de-escalate therapy in inflammatory bowel diseases
    • Pariente B, Laharie D. Review article: why, when and how to de-escalate therapy in inflammatory bowel diseases. Aliment Pharmacol Ther 2014; 40: 338–53.
    • (2014) Aliment Pharmacol Ther , vol.40 , pp. 338-353
    • Pariente, B.1    Laharie, D.2
  • 41
    • 19944431840 scopus 로고    scopus 로고
    • Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial
    • Quinn MA, Conaghan PG, O'Connor PJ, et al. Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2005; 52: 27–35.
    • (2005) Arthritis Rheum , vol.52 , pp. 27-35
    • Quinn, M.A.1    Conaghan, P.G.2    O'Connor, P.J.3
  • 42
    • 27744514865 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial
    • Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum 2005; 52: 3381–90.
    • (2005) Arthritis Rheum , vol.52 , pp. 3381-3390
    • Goekoop-Ruiterman, Y.P.1    de Vries-Bouwstra, J.K.2    Allaart, C.F.3
  • 43
    • 53549130270 scopus 로고    scopus 로고
    • Discontinuation of infliximab in rheumatoid arthritis patients in clinical remission
    • Nawata M, Saito K, Nakayamada S, Tanaka Y. Discontinuation of infliximab in rheumatoid arthritis patients in clinical remission. Mod Rheumatol 2008; 18: 460–4.
    • (2008) Mod Rheumatol , vol.18 , pp. 460-464
    • Nawata, M.1    Saito, K.2    Nakayamada, S.3    Tanaka, Y.4
  • 44
    • 77954973766 scopus 로고    scopus 로고
    • Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study
    • Tanaka Y, Takeuchi T, Mimori T, et al. Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study. Ann Rheum Dis 2010; 69: 1286–91.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1286-1291
    • Tanaka, Y.1    Takeuchi, T.2    Mimori, T.3
  • 45
    • 84898721366 scopus 로고    scopus 로고
    • Stopping anti-TNF agents in patients with crohn's disease in remission: is it a feasible long-term strategy?
    • Sorrentino D, Nash P, Viladomiu M, Hontecillas R, Bassaganya-Riera J. Stopping anti-TNF agents in patients with crohn's disease in remission: is it a feasible long-term strategy? Inflamm Bowel Dis 2014; 20: 757–66.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 757-766
    • Sorrentino, D.1    Nash, P.2    Viladomiu, M.3    Hontecillas, R.4    Bassaganya-Riera, J.5
  • 46
    • 36549071038 scopus 로고    scopus 로고
    • Clinical course in Crohn's disease: results of a Norwegian population-based ten-year follow-up study
    • Solberg IC, Vatn MH, Hoie O, et al. Clinical course in Crohn's disease: results of a Norwegian population-based ten-year follow-up study. Clin Gastroenterol Hepatol 2007; 5: 1430–8.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1430-1438
    • Solberg, I.C.1    Vatn, M.H.2    Hoie, O.3
  • 47
    • 84928814830 scopus 로고    scopus 로고
    • Assessment of the influence of inflammation and FCGR3A genotype on infliximab pharmacokinetics and time to relapse in patients with Crohn's disease
    • Ternant D, Berkane Z, Picon L, et al. Assessment of the influence of inflammation and FCGR3A genotype on infliximab pharmacokinetics and time to relapse in patients with Crohn's disease. Clin Pharmacokinet 2015; 54: 551–62.
    • (2015) Clin Pharmacokinet , vol.54 , pp. 551-562
    • Ternant, D.1    Berkane, Z.2    Picon, L.3
  • 49
    • 84883487000 scopus 로고    scopus 로고
    • Smoking does influence disease behaviour and impacts the need for therapy in Crohn's disease in the biologic era
    • Nunes T, Etchevers MJ, Domenech E, et al. Smoking does influence disease behaviour and impacts the need for therapy in Crohn's disease in the biologic era. Aliment Pharmacol Ther 2013; 38: 752–60.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 752-760
    • Nunes, T.1    Etchevers, M.J.2    Domenech, E.3
  • 50
    • 84904504746 scopus 로고    scopus 로고
    • Smoking in inflammatory bowel disease: impact on disease course and insights into the aetiology of its effect
    • Parkes GC, Whelan K, Lindsay JO. Smoking in inflammatory bowel disease: impact on disease course and insights into the aetiology of its effect. J Crohns Colitis 2014; 8: 717–25.
    • (2014) J Crohns Colitis , vol.8 , pp. 717-725
    • Parkes, G.C.1    Whelan, K.2    Lindsay, J.O.3
  • 51
    • 0037282938 scopus 로고    scopus 로고
    • Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn's disease
    • Van Assche G, Vanbeckevoort D, Bielen D, et al. Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn's disease. Am J Gastroenterol 2003; 98: 332–9.
    • (2003) Am J Gastroenterol , vol.98 , pp. 332-339
    • Van Assche, G.1    Vanbeckevoort, D.2    Bielen, D.3
  • 52
    • 78751682552 scopus 로고    scopus 로고
    • Long-term monitoring of infliximab therapy for perianal fistulizing Crohn's disease by using magnetic resonance imaging
    • Karmiris K, Bielen D, Vanbeckevoort D, et al. Long-term monitoring of infliximab therapy for perianal fistulizing Crohn's disease by using magnetic resonance imaging. Clin Gastroenterol Hepatol 2011; 9: 130–6.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 130-136
    • Karmiris, K.1    Bielen, D.2    Vanbeckevoort, D.3
  • 53
    • 84988937924 scopus 로고    scopus 로고
    • Effectiveness of Adalimumab in perianal fistulas in Crohn's disease Patients naive to anti-TNF therapy
    • Castano-Milla C, Chaparro M, Saro C, et al. Effectiveness of Adalimumab in perianal fistulas in Crohn's disease Patients naive to anti-TNF therapy. J Clin Gastroenterol 2015; 49: 34–40.
    • (2015) J Clin Gastroenterol , vol.49 , pp. 34-40
    • Castano-Milla, C.1    Chaparro, M.2    Saro, C.3
  • 54
    • 56449111531 scopus 로고    scopus 로고
    • Is the efficacy of successful infliximab induction therapy maintained for one year lasting without retreatment in different behavior types of Crohn's disease?
    • Molnar T, Farkas K, Miheller P, et al. Is the efficacy of successful infliximab induction therapy maintained for one year lasting without retreatment in different behavior types of Crohn's disease? J Crohns Colitis 2008; 2: 322–6.
    • (2008) J Crohns Colitis , vol.2 , pp. 322-326
    • Molnar, T.1    Farkas, K.2    Miheller, P.3
  • 55
    • 84887992627 scopus 로고    scopus 로고
    • Pouchitis: what every gastroenterologist needs to know
    • Shen B. Pouchitis: what every gastroenterologist needs to know. Clin Gastroenterol Hepatol 2013; 11: 1538–49.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 1538-1549
    • Shen, B.1
  • 56
    • 84884133175 scopus 로고    scopus 로고
    • Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis
    • Viazis N, Giakoumis M, Koukouratos T, et al. Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis. J Crohns Colitis 2013; 7: e457–60.
    • (2013) J Crohns Colitis , vol.7 , pp. e457-e460
    • Viazis, N.1    Giakoumis, M.2    Koukouratos, T.3
  • 57
  • 58
    • 84859017783 scopus 로고    scopus 로고
    • Close monitoring of CRP and fecal calprotectin levels to predict relapse in Crohn's disease patients. A sub-analysis of the STORI study
    • de Suray N, Salleron J, Vernier-Massouille G, et al. Close monitoring of CRP and fecal calprotectin levels to predict relapse in Crohn's disease patients. A sub-analysis of the STORI study. J Crohns Colitis 2012; 6S1: P274.
    • (2012) J Crohns Colitis , vol.6S1 , pp. P274
    • de Suray, N.1    Salleron, J.2    Vernier-Massouille, G.3
  • 59
    • 57449085396 scopus 로고    scopus 로고
    • Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease
    • Gisbert JP, McNicholl AG. Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease. Dig Liver Dis 2009; 41: 56–66.
    • (2009) Dig Liver Dis , vol.41 , pp. 56-66
    • Gisbert, J.P.1    McNicholl, A.G.2
  • 60
    • 84884823404 scopus 로고    scopus 로고
    • Role of endoscopy, cross-sectional imaging and biomarkers in Crohn's disease monitoring
    • Benitez JM, Meuwis MA, Reenaers C, Van Kemseke C, Meunier P, Louis E. Role of endoscopy, cross-sectional imaging and biomarkers in Crohn's disease monitoring. Gut 2013; 62: 1806–16.
    • (2013) Gut , vol.62 , pp. 1806-1816
    • Benitez, J.M.1    Meuwis, M.A.2    Reenaers, C.3    Van Kemseke, C.4    Meunier, P.5    Louis, E.6
  • 61
    • 84861869143 scopus 로고    scopus 로고
    • Fecal calprotectin in predicting relapse of inflammatory bowel diseases: a meta-analysis of prospective studies
    • Mao R, Xiao YL, Gao X, et al. Fecal calprotectin in predicting relapse of inflammatory bowel diseases: a meta-analysis of prospective studies. Inflamm Bowel Dis 2012; 18: 1894–9.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1894-1899
    • Mao, R.1    Xiao, Y.L.2    Gao, X.3
  • 62
    • 84904275688 scopus 로고    scopus 로고
    • Does fecal calprotectin predict short-term relapse after stopping tnfalpha-blocking agents in inflammatory bowel disease patients in deep remission?
    • Molander P, Farkkila M, Ristimaki A, et al. Does fecal calprotectin predict short-term relapse after stopping tnfalpha-blocking agents in inflammatory bowel disease patients in deep remission? J Crohns Colitis 2015; 9: 33–40.
    • (2015) J Crohns Colitis , vol.9 , pp. 33-40
    • Molander, P.1    Farkkila, M.2    Ristimaki, A.3
  • 63
    • 84902150181 scopus 로고    scopus 로고
    • Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease
    • Rajca S, Grondin V, Louis E, et al. Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease. Inflamm Bowel Dis 2014; 20: 978–86.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 978-986
    • Rajca, S.1    Grondin, V.2    Louis, E.3
  • 64
    • 84875725735 scopus 로고    scopus 로고
    • Systematic review: antibodies and anti-TNF-alpha levels in inflammatory bowel disease
    • Chaparro M, Guerra I, Munoz-Linares P, Gisbert JP. Systematic review: antibodies and anti-TNF-alpha levels in inflammatory bowel disease. Aliment Pharmacol Ther 2012; 35: 971–86.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 971-986
    • Chaparro, M.1    Guerra, I.2    Munoz-Linares, P.3    Gisbert, J.P.4
  • 65
    • 84930842615 scopus 로고    scopus 로고
    • Measurement of anti-TNF agents and anti-drug antibodies serum levels in patients with inflammatory bowel disease
    • Guerra I, Chaparro M, Bermejo F, Gisbert JP. Measurement of anti-TNF agents and anti-drug antibodies serum levels in patients with inflammatory bowel disease. Curr Drug Metab 2014; 15: 875–81.
    • (2014) Curr Drug Metab , vol.15 , pp. 875-881
    • Guerra, I.1    Chaparro, M.2    Bermejo, F.3    Gisbert, J.P.4
  • 66
    • 84886946831 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatments in inflammatory bowel disease
    • Ben-Horin S, Kopylov U, Chowers Y. Optimizing anti-TNF treatments in inflammatory bowel disease. Autoimmun Rev 2014; 13: 24–30.
    • (2014) Autoimmun Rev , vol.13 , pp. 24-30
    • Ben-Horin, S.1    Kopylov, U.2    Chowers, Y.3
  • 67
    • 84860130277 scopus 로고    scopus 로고
    • Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease
    • Armuzzi A, Van Assche G, Reinisch W, et al. Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease. J Crohns Colitis 2012; 6: 492–502.
    • (2012) J Crohns Colitis , vol.6 , pp. 492-502
    • Armuzzi, A.1    Van Assche, G.2    Reinisch, W.3
  • 68
    • 84896482819 scopus 로고    scopus 로고
    • Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy
    • Farkas K, Lakatos PL, Szucs M, et al. Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy. World J Gastroenterol 2014; 20: 2995–3001.
    • (2014) World J Gastroenterol , vol.20 , pp. 2995-3001
    • Farkas, K.1    Lakatos, P.L.2    Szucs, M.3
  • 69
    • 84875697403 scopus 로고    scopus 로고
    • Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease
    • Rismo R, Olsen T, Cui G, et al. Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease. Scand J Gastroenterol 2013; 48: 311–9.
    • (2013) Scand J Gastroenterol , vol.48 , pp. 311-319
    • Rismo, R.1    Olsen, T.2    Cui, G.3
  • 70
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
    • Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002; 359: 1541–9.
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 71
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 2007; 132: 52–65.
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 72
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review
    • Gisbert JP, Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol 2009; 104: 760–7.
    • (2009) Am J Gastroenterol , vol.104 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 73
    • 79953688705 scopus 로고    scopus 로고
    • Review article: loss of response to anti-TNF treatments in Crohn's disease
    • Ben-Horin S, Chowers Y. Review article: loss of response to anti-TNF treatments in Crohn's disease. Aliment Pharmacol Ther 2011; 33: 987–95.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 987-995
    • Ben-Horin, S.1    Chowers, Y.2
  • 74
    • 79958136275 scopus 로고    scopus 로고
    • Review article: causative factors and the clinical management of patients with Crohn's disease who lose response to anti-TNF-alpha therapy
    • Danese S, Fiorino G, Reinisch W. Review article: causative factors and the clinical management of patients with Crohn's disease who lose response to anti-TNF-alpha therapy. Aliment Pharmacol Ther 2011; 34: 1–10.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1-10
    • Danese, S.1    Fiorino, G.2    Reinisch, W.3
  • 75
    • 84872487090 scopus 로고    scopus 로고
    • Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patients
    • Baert F, Glorieus E, Reenaers C, et al. Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patients. J Crohns Colitis 2013; 7: 154–60.
    • (2013) J Crohns Colitis , vol.7 , pp. 154-160
    • Baert, F.1    Glorieus, E.2    Reenaers, C.3
  • 76
    • 84940731868 scopus 로고    scopus 로고
    • Dose de-escalation in patients with inflammatory bowel disease treated long-term with adalimumab 40 mg weekly
    • Karmiris K, Noman M, Vermeire S, van Assche G, Rutgeerts P. Dose de-escalation in patients with inflammatory bowel disease treated long-term with adalimumab 40 mg weekly. Gut 2008; 57(Suppl. III): A255.
    • (2008) Gut , vol.57 , pp. A255
    • Karmiris, K.1    Noman, M.2    Vermeire, S.3    van Assche, G.4    Rutgeerts, P.5
  • 77
    • 84894407889 scopus 로고    scopus 로고
    • Effectiveness of a dose “de-escalation” strategy with anti-TNF drugs in patients with Crohn's disease
    • Chaparro M, Barreiro-de Acosta M, Garcia-Planella E, et al. Effectiveness of a dose “de-escalation” strategy with anti-TNF drugs in patients with Crohn's disease. J Crohns Colitis 2011; 5: S103.
    • (2011) J Crohns Colitis , vol.5 , pp. S103
    • Chaparro, M.1    Barreiro-de Acosta, M.2    Garcia-Planella, E.3
  • 78
    • 85052043479 scopus 로고    scopus 로고
    • Outcomes after elective withdrawal of anti-TNF therapy in Crohn's disease: a multicentre study
    • Sebastian S, Robinson K, Warren L, et al. Outcomes after elective withdrawal of anti-TNF therapy in Crohn's disease: a multicentre study. J Crohns Colitis 2013; 7(Suppl. 1):S166–7.
    • (2013) J Crohns Colitis , vol.7 , pp. S166-S167
    • Sebastian, S.1    Robinson, K.2    Warren, L.3
  • 79
    • 0021266269 scopus 로고
    • Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery
    • Rutgeerts P, Geboes K, Vantrappen G, Kerremans R, Coenegrachts JL, Coremans G. Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery. Gut 1984; 25: 665–72.
    • (1984) Gut , vol.25 , pp. 665-672
    • Rutgeerts, P.1    Geboes, K.2    Vantrappen, G.3    Kerremans, R.4    Coenegrachts, J.L.5    Coremans, G.6
  • 80
    • 69949153607 scopus 로고    scopus 로고
    • Management and prevention of postoperative Crohn's disease
    • Regueiro M. Management and prevention of postoperative Crohn's disease. Inflamm Bowel Dis 2009; 15: 1583–90.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1583-1590
    • Regueiro, M.1
  • 81
    • 58649121974 scopus 로고    scopus 로고
    • Infliximab prevents Crohn's disease recurrence after ileal resection
    • quiz 716
    • Regueiro M, Schraut W, Baidoo L, et al. Infliximab prevents Crohn's disease recurrence after ileal resection. Gastroenterology 2009; 136: 441–50 e441; quiz 716.
    • (2009) Gastroenterology , vol.136 , pp. 441-450
    • Regueiro, M.1    Schraut, W.2    Baidoo, L.3
  • 82
    • 84876457416 scopus 로고    scopus 로고
    • Low-dose maintenance therapy with infliximab prevents postsurgical recurrence of Crohn's disease
    • quiz e578-599
    • Sorrentino D, Paviotti A, Terrosu G, Avellini C, Geraci M, Zarifi D. Low-dose maintenance therapy with infliximab prevents postsurgical recurrence of Crohn's disease. Clin Gastroenterol Hepatol 2010; 8: 591–9 e591; quiz e578-599.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 591-599
    • Sorrentino, D.1    Paviotti, A.2    Terrosu, G.3    Avellini, C.4    Geraci, M.5    Zarifi, D.6
  • 83
    • 84884216502 scopus 로고    scopus 로고
    • Management of postoperative recurrence of Crohn's disease
    • van Lent AU, D'Haens GR. Management of postoperative recurrence of Crohn's disease. Dig Dis 2013; 31: 222–8.
    • (2013) Dig Dis , vol.31 , pp. 222-228
    • van Lent, A.U.1    D'Haens, G.R.2
  • 84
    • 84883743884 scopus 로고    scopus 로고
    • Safety of anti-TNF agents during pregnancy and breastfeeding in women with inflammatory bowel disease
    • Gisbert JP, Chaparro M. Safety of anti-TNF agents during pregnancy and breastfeeding in women with inflammatory bowel disease. Am J Gastroenterol 2013; 108: 1426–38.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1426-1438
    • Gisbert, J.P.1    Chaparro, M.2
  • 85
    • 79955601056 scopus 로고    scopus 로고
    • Transplacental transfer of immunosuppressants and biologics used for the treatment of inflammatory bowel disease
    • Chaparro M, Gisbert JP. Transplacental transfer of immunosuppressants and biologics used for the treatment of inflammatory bowel disease. Curr Pharm Biotechnol 2011; 12: 765–73.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 765-773
    • Chaparro, M.1    Gisbert, J.P.2
  • 86
    • 84912045381 scopus 로고    scopus 로고
    • How safe is infliximab therapy during pregnancy and lactation in inflammatory bowel disease?
    • Chaparro M, Gisbert JP. How safe is infliximab therapy during pregnancy and lactation in inflammatory bowel disease? Expert Opin Drug Saf 2014; 13: 1749–62.
    • (2014) Expert Opin Drug Saf , vol.13 , pp. 1749-1762
    • Chaparro, M.1    Gisbert, J.P.2
  • 87
    • 84874569090 scopus 로고    scopus 로고
    • Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure
    • Zelinkova Z, van der Ent C, Bruin KF, et al. Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure. Clin Gastroenterol Hepatol 2013; 11: 318–21.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 318-321
    • Zelinkova, Z.1    van der Ent, C.2    Bruin, K.F.3
  • 88
    • 84912071309 scopus 로고    scopus 로고
    • Anti-TNF is safe to stop in the second trimester of pregnancy in IBD women in remission
    • de Lima A, Zelinkova Z, der van Ent C, der van Woude CJ. Anti-TNF is safe to stop in the second trimester of pregnancy in IBD women in remission. Gastroenterology 2014; 146(Suppl. 1): 340.
    • (2014) Gastroenterology , vol.146 , pp. 340
    • de Lima, A.1    Zelinkova, Z.2    der van, E.C.3    der van Woude, C.J.4
  • 89
    • 84880060478 scopus 로고    scopus 로고
    • Biologic therapy in inflammatory bowel disease
    • Theede K, Dahlerup JF, Fallingborg J, et al. Biologic therapy in inflammatory bowel disease. Dan Med J 2013; 60: B4652.
    • (2013) Dan Med J , vol.60 , pp. B4652
    • Theede, K.1    Dahlerup, J.F.2    Fallingborg, J.3
  • 91
    • 84862899257 scopus 로고    scopus 로고
    • A prospective study of infliximab withdrawal after 12 months of treatment in patients with Crohn's disease: how will NICE guidance affect patient care?
    • Blackmore L, Harris A. A prospective study of infliximab withdrawal after 12 months of treatment in patients with Crohn's disease: how will NICE guidance affect patient care? Clin Med 2012; 12: 235–8.
    • (2012) Clin Med , vol.12 , pp. 235-238
    • Blackmore, L.1    Harris, A.2
  • 92
    • 79751472562 scopus 로고    scopus 로고
    • The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?
    • quiz 213
    • D'Haens GR, Panaccione R, Higgins PD, et al. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol 2011; 106: 199–212; quiz 213.
    • (2011) Am J Gastroenterol , vol.106 , pp. 199-212
    • D'Haens, G.R.1    Panaccione, R.2    Higgins, P.D.3
  • 93
    • 84884138341 scopus 로고    scopus 로고
    • When do we dare to stop biological or immunomodulatory therapy for Crohn's disease? Results of a multidisciplinary European expert panel
    • Pittet V, Froehlich F, Maillard MH, et al. When do we dare to stop biological or immunomodulatory therapy for Crohn's disease? Results of a multidisciplinary European expert panel. J Crohns Colitis 2013; 7: 820–6.
    • (2013) J Crohns Colitis , vol.7 , pp. 820-826
    • Pittet, V.1    Froehlich, F.2    Maillard, M.H.3
  • 94
    • 0037379792 scopus 로고    scopus 로고
    • Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized controlled trial
    • Farrell RJ, Alsahli M, Jeen YT, Falchuk KR, Peppercorn MA, Michetti P. Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized controlled trial. Gastroenterology 2003; 124: 917–24.
    • (2003) Gastroenterology , vol.124 , pp. 917-924
    • Farrell, R.J.1    Alsahli, M.2    Jeen, Y.T.3    Falchuk, K.R.4    Peppercorn, M.A.5    Michetti, P.6
  • 95
    • 85006328379 scopus 로고    scopus 로고
    • Retreatment with infliximab in inflammatory bowel disease: tolerability and effectiveness of different re-induction regimens
    • Felice C, Pugliese D, Guidi L, et al. Retreatment with infliximab in inflammatory bowel disease: tolerability and effectiveness of different re-induction regimens.J Crohns Colitis 2014; 8(Suppl.1): P363.
    • (2014) J Crohns Colitis , vol.8 , pp. P363
    • Felice, C.1    Pugliese, D.2    Guidi, L.3
  • 96
    • 84884570777 scopus 로고    scopus 로고
    • Ten years of infliximab for Crohn's disease: outcome in 469 patients from 2 tertiary referral centers
    • Eshuis EJ, Peters CP, van Bodegraven AA, et al. Ten years of infliximab for Crohn's disease: outcome in 469 patients from 2 tertiary referral centers. Inflamm Bowel Dis 2013; 19: 1622–30.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1622-1630
    • Eshuis, E.J.1    Peters, C.P.2    van Bodegraven, A.A.3
  • 97
    • 84906791611 scopus 로고    scopus 로고
    • Early trough levels and antibodies to infliximab predict safety and success of reinitiation of infliximab therapy
    • quiz e1491
    • Baert F, Drobne D, Gils A, et al. Early trough levels and antibodies to infliximab predict safety and success of reinitiation of infliximab therapy. Clin Gastroenterol Hepatol  2014; 12: 1474–81 e1472; quiz e1491.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 1474-1481
    • Baert, F.1    Drobne, D.2    Gils, A.3
  • 98
    • 75149119829 scopus 로고    scopus 로고
    • Infliximab reintroduction is not associated to a higher rate of immune-related adverse effects in patients with inflammatory bowel disease initially treated with a three-infusion induction regimen
    • Domenech E, Zabana Y, Manosa M, Garcia-Planella E, Cabre E, Gassull MA. Infliximab reintroduction is not associated to a higher rate of immune-related adverse effects in patients with inflammatory bowel disease initially treated with a three-infusion induction regimen. J Clin Gastroenterol 2010; 44: 34–7.
    • (2010) J Clin Gastroenterol , vol.44 , pp. 34-37
    • Domenech, E.1    Zabana, Y.2    Manosa, M.3    Garcia-Planella, E.4    Cabre, E.5    Gassull, M.A.6


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