Impact of MYH6 variants in hypoplastic left heart syndrome

Physiological Genomics

Volumn 48, Issue 12, 2016, Pages 912-921

  Tomita Mitchell, Aoy ^a   Stamm, Karl D ^a,b   Mahnke, Donna K ^a   Kim, Min Su ^a   Hidestrand, Pip M ^e   Liang, Huan Ling ^a   Goetsch, Mary A ^a   Hidestrand, Mats ^a   Simpson, Pippa ^a   Pelech, Andrew N ^d   Tweddell, James S ^c   Benson, D Woodrow ^a   Lough, John W ^a   Mitchell, Michael E ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b MARQUETTE UNIVERSITY   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d University of California at Davis School of Medicine   (United States)

^e EASTERN MAINE MEDICAL CENTER   (United States)

Author keywords

Cardiomyocyte autonomous; Genetics; Hypoplastic left heart syndrome; Transplant free survival outcome; Upregulation of contractility genes

Indexed keywords

ALPHA ACTIN; ALPHA ACTIN 1; BIOLOGICAL MARKER; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; MYOSIN LIGHT CHAIN 2; TRANSCRIPTOME; TROPONIN T; TROPONIN T2; UNCLASSIFIED DRUG; CARDIAC MYOSIN; MYH6 PROTEIN, HUMAN; MYOSIN HEAVY CHAIN;

ARTICLE; CARDIAC MUSCLE CELL; CASE CONTROL STUDY; CELL DIFFERENTIATION; CHILD; CLINICAL OUTCOME; CONGENITAL HEART DISEASE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEART MUSCLE CONTRACTILITY; HEART TISSUE; HEART TRANSPLANTATION; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN GENOME PROJECT; HUMAN TISSUE; HYPOPLASTIC LEFT HEART SYNDROME; IN VITRO STUDY; IN VIVO STUDY; INDUCED PLURIPOTENT STEM CELL; INFANT; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NEWBORN; NEXT GENERATION SEQUENCING; PEDIATRIC CARDIOLOGY; PEDIGREE ANALYSIS; PHENOTYPE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; STOP CODON; SURVIVAL; SURVIVAL ANALYSIS; TRANSCRIPTOMICS; TRANSPLANT FREE SURVIVAL; UPREGULATION; ADOLESCENT; GENETICS; MUTATION; PEDIGREE; PHYSIOLOGY;

ADOLESCENT; CARDIAC MYOSINS; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; FEMALE; HUMANS; HYPOPLASTIC LEFT HEART SYNDROME; INDUCED PLURIPOTENT STEM CELLS; MALE; MUTATION; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; PEDIGREE; TRANSCRIPTOME; UP-REGULATION;

EID: 85006309110     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00091.2016     Document Type: Article

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