메뉴 건너뛰기




Volumn 26, Issue 12, 2016, Pages 1681-1692

Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis

Author keywords

chronic autoimmune thyroiditis; clinical effect; Hashimoto's thyroiditis; meta analysis; selenium supplementation; systematic review

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEVOTHYROXINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; SELENIUM; SELENOMETHIONINE; SODIUM SELENITE; THYROGLOBULIN ANTIBODY; THYROID ANTIBODY; THYROID PEROXIDASE ANTIBODY; TUMOR NECROSIS FACTOR; AUTOANTIBODY; IODIDE PEROXIDASE; THYROGLOBULIN;

EID: 85006253371     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2016.0256     Document Type: Article
Times cited : (152)

References (65)
  • 1
    • 80052703117 scopus 로고    scopus 로고
    • The epidemiology of thyroid disease
    • Vanderpump MP 2011 The epidemiology of thyroid disease. Br Med Bull 99:39-51.
    • (2011) Br Med Bull , vol.99 , pp. 39-51
    • Vanderpump, M.P.1
  • 3
    • 84905723129 scopus 로고    scopus 로고
    • Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism
    • Wiersinga WM 2014 Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism. Nat Rev En-docrinol 10:164-174.
    • (2014) Nat Rev En-docrinol , vol.10 , pp. 164-174
    • Wiersinga, W.M.1
  • 4
    • 84884174438 scopus 로고    scopus 로고
    • Type and extent of somatic morbidity before and after the diagnosis of hypothyroidism. A nationwide register study
    • Thvilum M, Brandt F, Almind D, Christensen K, Brix TH, Hegedüs L 2013 Type and extent of somatic morbidity before and after the diagnosis of hypothyroidism. A nationwide register study. PLoS One 8:e75789.
    • (2013) PLoS One , vol.8 , pp. e75789
    • Thvilum, M.1    Brandt, F.2    Almind, D.3    Christensen, K.4    Brix, T.H.5    Hegedüs, L.6
  • 5
    • 84899477139 scopus 로고    scopus 로고
    • Increased psychiatric morbidity before and after the diagnosis of hypothyroidism: A nationwide register study
    • Thvilum M, Brandt F, Almind D, Christensen K, Brix TH, Hegedüs L 2014 Increased psychiatric morbidity before and after the diagnosis of hypothyroidism: a nationwide register study. Thyroid 24:802-808.
    • (2014) Thyroid , vol.24 , pp. 802-808
    • Thvilum, M.1    Brandt, F.2    Almind, D.3    Christensen, K.4    Brix, T.H.5    Hegedüs, L.6
  • 6
    • 84907201182 scopus 로고    scopus 로고
    • Hy-pothyroidism is a predictor of disability pension and loss of labor market income: A Danish register-based study
    • Thvilum M, Brandt F, Brix TH, Hegedüs L 2014 Hy-pothyroidism is a predictor of disability pension and loss of labor market income: a Danish register-based study. J Clin Endocrinol Metab 99:3129-3135.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. 3129-3135
    • Thvilum, M.1    Brandt, F.2    Brix, T.H.3    Hegedüs, L.4
  • 7
    • 84874920936 scopus 로고    scopus 로고
    • Excess mortality in patients diagnosed with hypothyroidism: A nationwide cohort study of singletons and twins
    • Thvilum M, Brandt F, Almind D, Christensen K, Hegedüs L, Brix TH 2013 Excess mortality in patients diagnosed with hypothyroidism: a nationwide cohort study of singletons and twins. J Clin Endocrinol Metab 98:1069-1075.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1069-1075
    • Thvilum, M.1    Brandt, F.2    Almind, D.3    Christensen, K.4    Hegedüs, L.5    Brix, T.H.6
  • 8
    • 0034453053 scopus 로고    scopus 로고
    • A population-based study of chronic autoimmune hypothyroidism in Danish twins
    • Brix TH, Kyvik KO, Hegedüs L 2000A population-based study of chronic autoimmune hypothyroidism in Danish twins. J Clin Endocrinol Metab 85:536-539.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 536-539
    • Brix, T.H.1    Kyvik, K.O.2    Hegedüs, L.3
  • 10
    • 84859211841 scopus 로고    scopus 로고
    • Selenium and human health
    • Rayman MP 2012 Selenium and human health. Lancet 379:1256-1268.
    • (2012) Lancet , vol.379 , pp. 1256-1268
    • Rayman, M.P.1
  • 11
    • 55949103249 scopus 로고    scopus 로고
    • On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis and human health
    • Schomburg L, Köhrle J 2008 On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis and human health. Mol Nutr Food Res 52:1235-1246.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 1235-1246
    • Schomburg, L.1    Köhrle, J.2
  • 13
    • 77957894604 scopus 로고    scopus 로고
    • Selenium supplementation in the treatment of Hashimoto's thyroiditis: A systematic review and a meta-analysis
    • Toulis KA, Anastasilakis AD, Tzellos TG, Goulis DG, Kouvelas D 2010 Selenium supplementation in the treatment of Hashimoto's thyroiditis: a systematic review and a meta-analysis. Thyroid 20:1163-1173.
    • (2010) Thyroid , vol.20 , pp. 1163-1173
    • Toulis, K.A.1    Anastasilakis, A.D.2    Tzellos, T.G.3    Goulis, D.G.4    Kouvelas, D.5
  • 14
    • 0038069523 scopus 로고    scopus 로고
    • Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis
    • Duntas LH, Mantzou E, Koutras DA 2003 Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis. Eur J Endocrinol 148:389-393.
    • (2003) Eur J Endocrinol , vol.148 , pp. 389-393
    • Duntas, L.H.1    Mantzou, E.2    Koutras, D.A.3
  • 15
    • 33746662815 scopus 로고    scopus 로고
    • Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses
    • Turker O, Kumanlioglu K, Karapolat I, Dogan I 2006 Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses. J Endocrinol 190:151-156.
    • (2006) J Endocrinol , vol.190 , pp. 151-156
    • Turker, O.1    Kumanlioglu, K.2    Karapolat, I.3    Dogan, I.4
  • 16
    • 0036269516 scopus 로고    scopus 로고
    • Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations
    • Gärtner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW 2002 Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab 87:1687-1691.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1687-1691
    • Gärtner, R.1    Gasnier, B.C.2    Dietrich, J.W.3    Krebs, B.4    Angstwurm, M.W.5
  • 17
    • 38649132640 scopus 로고    scopus 로고
    • No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis
    • Karanikas G, Schuetz M, Kontur S 2008 No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis. Thyroid 18:7-12.
    • (2008) Thyroid , vol.18 , pp. 7-12
    • Karanikas, G.1    Schuetz, M.2    Kontur, S.3
  • 19
    • 84919800581 scopus 로고    scopus 로고
    • Selenium supplementation for autoimmune thyroiditis: A systematic review and meta-analysis
    • Fan Y, Xu S, Zhang H, Cao W, Wang K, Chen G, Di H, Cao M, Liu C 2014 Selenium supplementation for autoimmune thyroiditis: a systematic review and meta-analysis. Int J Endocrinol 2014:904573.
    • (2014) Int J Endocrinol , vol.2014 , pp. 904573
    • Fan, Y.1    Xu, S.2    Zhang, H.3    Cao, W.4    Wang, K.5    Chen, G.6    Di, H.7    Cao, M.8    Liu, C.9
  • 31
    • 85007610824 scopus 로고    scopus 로고
    • IFNgamma-inducible chemo-kines decrease upon selenomethionine supplementation in women with euthyroid autoimmune thyroiditis: Comparison between two doses of selenomethionine (80 or 160 lg) versus placebo
    • Pilli T, Cantara S, Schomburg L, Cenci V, Cardinale S, Heid EC, Kühn EC, Cevenini G, Sestini F, Fioravanti C, D'Hauw G, Pacini F 2015 IFNgamma-inducible chemo-kines decrease upon selenomethionine supplementation in women with euthyroid autoimmune thyroiditis: comparison between two doses of selenomethionine (80 or 160 lg) versus placebo. Eur Thyroid J 4:226-233.
    • (2015) Eur Thyroid J , vol.4 , pp. 226-233
    • Pilli, T.1    Cantara, S.2    Schomburg, L.3    Cenci, V.4    Cardinale, S.5    Heid, E.C.6    Kühn, E.C.7    Cevenini, G.8    Sestini, F.9    Fioravanti, C.10    D'Hauw, G.11    Pacini, F.12
  • 33
    • 79960077553 scopus 로고    scopus 로고
    • The effect of levothyroxine and selenomethionine on lymphocyte and monocyte cyto-kine release in women with Hashimoto's thyroiditis
    • Krysiak R, Okopien B 2011 The effect of levothyroxine and selenomethionine on lymphocyte and monocyte cyto-kine release in women with Hashimoto's thyroiditis. J Clin Endocrinol Metab 96:2206-2215.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2206-2215
    • Krysiak, R.1    Okopien, B.2
  • 34
    • 84870379884 scopus 로고    scopus 로고
    • Haemostatic effects of le-vothyroxine and selenomethionine in euthyroid patients with Hashimoto's thyroiditis
    • Krysiak R, Okopien B 2012 Haemostatic effects of le-vothyroxine and selenomethionine in euthyroid patients with Hashimoto's thyroiditis. Thromb Haemost 108:973-980.
    • (2012) Thromb Haemost , vol.108 , pp. 973-980
    • Krysiak, R.1    Okopien, B.2
  • 36
    • 48049094747 scopus 로고    scopus 로고
    • The effect of selenium therapy on autoimmune thyroiditis
    • Balazs C 2008 [The effect of selenium therapy on autoimmune thyroiditis]. Orv Hetil 149:1227-1232.
    • (2008) Orv Hetil , vol.149 , pp. 1227-1232
    • Balazs, C.1
  • 37
    • 85006297958 scopus 로고    scopus 로고
    • Selenomethionine supplementation in euthyroid patients with autoimmune thy-roiditis
    • Cenci V, Pilli T, Cardinale S 2013 Selenomethionine supplementation in euthyroid patients with autoimmune thy-roiditis. Eur Thyroid J 2:134.
    • (2013) Eur Thyroid J , vol.2 , pp. 134
    • Cenci, V.1    Pilli, T.2    Cardinale, S.3
  • 38
    • 85006301955 scopus 로고    scopus 로고
    • Effects of selenium supplementation on TPOAb in active autoimmune thyroiditis
    • Ciric S 2011 Effects of selenium supplementation on TPOAb in active autoimmune thyroiditis. Eur Thyroid J 1:136.
    • (2011) Eur Thyroid J , vol.1 , pp. 136
    • Ciric, S.1
  • 39
    • 85006289738 scopus 로고    scopus 로고
    • Selenium supplementation in pregnant women with chronic autoimmune thyroiditis: Effects on selenium, serum concentration and autoimmune parameters
    • Duntas L, Boutsiadis A, Mantzou E 2013 Selenium supplementation in pregnant women with chronic autoimmune thyroiditis: effects on selenium, serum concentration and autoimmune parameters. Eur Thyroid J 2:92-93.
    • (2013) Eur Thyroid J , vol.2 , pp. 92-93
    • Duntas, L.1    Boutsiadis, A.2    Mantzou, E.3
  • 40
    • 85006299018 scopus 로고    scopus 로고
    • Selenium supplementation in euthyroid patients with autoimmune thyroiditis. A pilot controlled study
    • Guglielmi R, Misischi I, Graziano F 2013 Selenium supplementation in euthyroid patients with autoimmune thyroiditis. A pilot controlled study. Eur Thyroid J 2: 152.
    • (2013) Eur Thyroid J , vol.2 , pp. 152
    • Guglielmi, R.1    Misischi, I.2    Graziano, F.3
  • 41
    • 85010768690 scopus 로고    scopus 로고
    • Affects selenium indeed concentrations of serum autoantibodies TPOAb and TGAb?
    • Kvicala J, Hrda P, Zamrazil V 2010 Affects selenium indeed concentrations of serum autoantibodies TPOAb and TGAb? Trace Elem Electrolytes 27:167.
    • (2010) Trace Elem Electrolytes , vol.27 , pp. 167
    • Kvicala, J.1    Hrda, P.2    Zamrazil, V.3
  • 42
    • 84957434322 scopus 로고    scopus 로고
    • Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency
    • Mao J, Pop VJ, Bath SC, Vader HL, Redman CW, Ray-man MP 2016 Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency. Eur J Nutr 55:55-61.
    • (2016) Eur J Nutr , vol.55 , pp. 55-61
    • Mao, J.1    Pop, V.J.2    Bath, S.C.3    Vader, H.L.4    Redman, C.W.5    Ray-Man, M.P.6
  • 43
    • 34147129879 scopus 로고    scopus 로고
    • The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies
    • Negro R, Greco G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H 2007 The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol Metab 92:1263-1268.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1263-1268
    • Negro, R.1    Greco, G.2    Mangieri, T.3    Pezzarossa, A.4    Dazzi, D.5    Hassan, H.6
  • 44
    • 84886542363 scopus 로고    scopus 로고
    • Combined treatment with Myo-inositol and selenium ensures euthyroidism in subclinical hypothyroidism patients with autoimmune thyroiditis
    • Nordio M, Pajalich R 2013 Combined treatment with Myo-inositol and selenium ensures euthyroidism in subclinical hypothyroidism patients with autoimmune thyroiditis. J Thyroid Res 2013:424163.
    • (2013) J Thyroid Res , vol.2013 , pp. 424163
    • Nordio, M.1    Pajalich, R.2
  • 45
    • 64849085636 scopus 로고    scopus 로고
    • Selenium supplementation in autoimmune thyroiditis female patient-effects on thyroid and ovarian functions (case study)
    • Zagrodzki P, Ratajczak R 2008 Selenium supplementation in autoimmune thyroiditis female patient-effects on thyroid and ovarian functions (case study). Biol Trace Elem Res 126:76-82.
    • (2008) Biol Trace Elem Res , vol.126 , pp. 76-82
    • Zagrodzki, P.1    Ratajczak, R.2
  • 46
    • 0842326443 scopus 로고    scopus 로고
    • Selenium in the treatment of autoimmune thyroiditis
    • Gärtner R, Gasnier BC 2003 Selenium in the treatment of autoimmune thyroiditis. Biofactors 19:165-170.
    • (2003) Biofactors , vol.19 , pp. 165-170
    • Gärtner, R.1    Gasnier, B.C.2
  • 54
    • 46349086115 scopus 로고    scopus 로고
    • Effects of selenium supplementation on TPOAb and cytokines in acute autoimmune thyroiditis
    • author reply 673-664
    • Gärtner R, Duntas LH 2008 Effects of selenium supplementation on TPOAb and cytokines in acute autoimmune thyroiditis. Thyroid 18:669-670; author reply 673-664.
    • (2008) Thyroid , vol.18 , pp. 669-670
    • Gärtner, R.1    Duntas, L.H.2
  • 55
    • 46349102760 scopus 로고    scopus 로고
    • There is immunological benefit of selenium treatment in autoimmune thyroiditis
    • Turker O, Karapolat I 2008 There is immunological benefit of selenium treatment in autoimmune thyroiditis. Thyroid 18:671-672.
    • (2008) Thyroid , vol.18 , pp. 671-672
    • Turker, O.1    Karapolat, I.2
  • 56
    • 0025896054 scopus 로고
    • Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis
    • Hegedüs L, Hansen JM, Feldt-Rasmussen U, Hansen BM, Høier-Madsen M 1991 Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis. Clin Endocrinol (Oxf) 35:235-238.
    • (1991) Clin Endocrinol (Oxf) , vol.35 , pp. 235-238
    • Hegedüs, L.1    Hansen, J.M.2    Feldt-Rasmussen, U.3    Hansen, B.M.4    Høier-Madsen, M.5
  • 57
    • 47549110745 scopus 로고    scopus 로고
    • Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothy-roxine
    • Schmidt M, Voell M, Rahlff I, Dietlein M, Kobe C, Faust M, Schicha H 2008 Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothy-roxine. Thyroid 18:755-760.
    • (2008) Thyroid , vol.18 , pp. 755-760
    • Schmidt, M.1    Voell, M.2    Rahlff, I.3    Dietlein, M.4    Kobe, C.5    Faust, M.6    Schicha, H.7
  • 59
    • 77950189829 scopus 로고    scopus 로고
    • CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials
    • Schulz KF, Altman DG, Moher D 2010 CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMJ 340:c332.
    • (2010) BMJ , vol.340 , pp. c332
    • Schulz, K.F.1    Altman, D.G.2    Moher, D.3
  • 60
    • 84892697192 scopus 로고    scopus 로고
    • Radio-immunoassay, enzyme and non-enzyme-based immunoas-says
    • Grange RD, Thompson JP, Lambert DG 2014 Radio-immunoassay, enzyme and non-enzyme-based immunoas-says. Br J Anaesth 112:213-216.
    • (2014) Br J Anaesth , vol.112 , pp. 213-216
    • Grange, R.D.1    Thompson, J.P.2    Lambert, D.G.3
  • 61
    • 51649103494 scopus 로고    scopus 로고
    • Epitope recognition patterns of thyroid peroxidase auto-antibodies in healthy individuals and patients with Hashimoto's thyroiditis
    • Nielsen CH, Brix TH, Gardas A, Banga JP, Hegedus L 2008 Epitope recognition patterns of thyroid peroxidase auto-antibodies in healthy individuals and patients with Hashimoto's thyroiditis. Clin Endocrinol (Oxf) 69:664-668.
    • (2008) Clin Endocrinol (Oxf) , vol.69 , pp. 664-668
    • Nielsen, C.H.1    Brix, T.H.2    Gardas, A.3    Banga, J.P.4    Hegedus, L.5
  • 65
    • 85006304082 scopus 로고    scopus 로고
    • Selenium in the treatment of thyroid diseases. An element in search of the relevant indications?
    • Hegedüs L, Bonnema SJ, Winther KH 2016 Selenium in the treatment of thyroid diseases. An element in search of the relevant indications? Eur Thyroid J 5:149-151.
    • (2016) Eur Thyroid J , vol.5 , pp. 149-151
    • Hegedüs, L.1    Bonnema, S.J.2    Winther, K.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.