The effect of levothyroxine and selenomethionine on lymphocyte and monocyte cytokine release in women with Hashimoto's thyroiditis

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 7, 2011, Pages 2206-2215

  Krysiak, Robert ^a   Okopien, Boguslaw ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; LEVOTHYROXINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; SELENOMETHIONINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL SYMPTOM; GLUCOSE METABOLISM; HASHIMOTO DISEASE; HUMAN; HYPERTHYROIDISM; INFLAMMATION; LYMPHOCYTE; MAJOR CLINICAL STUDY; MONOCYTE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; C-REACTIVE PROTEIN; CYTOKINES; FEMALE; HASHIMOTO DISEASE; HUMANS; LYMPHOCYTES; MIDDLE AGED; MONOCYTES; SELENOMETHIONINE; THYROXINE;

EID: 79960077553     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2010-2986     Document Type: Article

References (38)

1. Caturegli P, Kimura H, Rocchi R, Rose NR 2007 Autoimmune thyroid diseases. Curr Opin Rheumatol 19:44-48
2. Lorini R, Gastaldi R, Traggiai C, Perucchin PP 2003 Hashimoto's thyroiditis. Pediatr Endocrinol Rev 1(Suppl 2):205-211 (Pubitemid 40204095)
3. Betterle C, Zanchetta R 2003 Update on autoimmune polyendocrine syndromes (APS). Acta Biomed 74:9-33 (Pubitemid 36850394)
4. Brown RS 2009 Autoimmune thyroid disease: unlocking a complex puzzle. Curr Opin Pediatr 21:523-528
5. Turker O, Kumanlioglu K, Karapolat I, Dogan I 2006 Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses. J Endocrinol 190:151-156 (Pubitemid 44161070)
6. Gärtner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW 2002 Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab 87:1687-1691 (Pubitemid 34618503)
7. Duntas LH, Mantzou E, Koutras DA 2003 Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis. Eur J Endocrinol 148:389-393 (Pubitemid 36527409)
8. Mazokopakis EE, Papadakis JA, Papadomanolaki MG, Batistakis AG, Giannakopoulos TG, Protopapadakis EE, Ganotakis ES 2007 Effects of 12 months treatment with L-selenomethionine on serum anti-TPO levels in patients with Hashimoto's thyroiditis. Thyroid 17:609-612 (Pubitemid 47311547)
9. Toulis KA, Anastasilakis AD, Tzellos TG, Goulis DG, Kouvelas D 2010 Selenium supplementation in the treatment of Hashimoto's thyroiditis: a systematic review and a meta-analysis. Thyroid 20:1163-1173
10. Negro R, Greco G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H 2007 The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol Metab 92:1263-1268 (Pubitemid 46556396)
11. Scarpa V, Kousta E, Tertipi A, Vakaki M, Fotinou A, Petrou V, Hadjiathanasiou C, Papathanasiou A 2010 Treatment with thyroxine reduces thyroid volume in euthyroid children and adolescents with chronic autoimmune thyroiditis. Horm Res Paediatr 73:61-67
12. Aksoy DY, Kerimoglu U, Okur H, Canpinar H, Karaaǧaoǧ lu E, Yetgin S, Kansu E, Gedik O 2005 Effects of prophylactic thyroid hormone replacement in euthyroid Hashimoto's thyroiditis. Endocr J 52:337-343 (Pubitemid 41003525)
13. Mussa GC, Corrias A, Mostert M, Pellegrino D, Silvestro L 1998 Patients with Hashimoto's disease treated with L-thyroxine and followed for three years. J Pediatr Endocrinol Metab 11:59-62 (Pubitemid 28110754)
14. Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H 2006 Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab 91:2587-2591 (Pubitemid 44024622)
15. Nicholson LB, Raveney BJ, Munder M 2009 Monocyte dependent regulation of autoimmune inflammation. Curr Mol Med 9:23-29
16. Piccirillo CA 2008 Regulatory T cells in health and disease. Cytokine 43:395-401
17. Romagnani S 1999 Th1/Th2 cells. Inflamm Bowel Dis 5:285-294
18. Matei I, Matei L 2002 Cytokine patterns and pathogenicity in autoimmune diseases. Rom J Intern Med 40:27-41
19. Tedgui A, Mallat Z 2006 Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 86:515-581
20. Isomäki P, Punnonen J 1997 Pro- and anti-inflammatory cytokines in rheumatoid arthritis. Ann Med 29:499-507 (Pubitemid 28135102)
21. Okopien B, Krysiak R, Kowalski J, Madej A, Belowski D, Zieliñski M, Herman ZS 2005 Monocyte release of tumor necrosis factor-α and interleukin-1β in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates. J Cardiovasc Pharmacol 46:377-386 (Pubitemid 41262842)
22. Okopien B, Krysiak R, Kowalski J, Madej A, Belowski D, Zieliñski M, Labuzek K, Herman ZS 2004 The effect of statins and fibrates on interferon-γ and interleukin-2 release in patients with primary type II dyslipidemia. Atherosclerosis 176:327-335 (Pubitemid 39369523)
23. Marnell L, Mold C, Du Clos TW 2005 C-reactive protein: ligands, receptors and role in inflammation. Clin Immunol 117:104-111 (Pubitemid 41407719)
24. Kłapcinska B, Poprzecki S, Danch A, Sobczak A, Kempa K 2005 Selenium levels in blood of upper Silesian population: evidence of suboptimal selenium status in a significant percentage of the population. Biol Trace Elem Res 108:1-15 (Pubitemid 41752495)
25. Stamatelopoulos KS, Kyrkou K, Chrysochoou E, Karga H, Chatzidou S, Georgiopoulos G, Georgiou S, Xiromeritis K, Papamichael CM, Alevizaki M 2009 Arterial stiffness but not intima-media thickness is increased in euthyroid patients with Hashimoto's thyroiditis: The effect of menopausal status. Thyroid 19:857-862
26. Ciccone MM, De Pergola G, Porcelli MT, Scicchitano P, Caldarola P, Iacoviello M, Pietro G, Giorgino F, Favale S 2010 Increased carotid IMT in overweight and obese women affected by Hashimoto's thyroiditis: an adiposity and autoimmune linkage?BMCCardiovasc Disord 10:22-29
27. Hansson GK 2009 Inflammatory mechanisms in atherosclerosis. J Thromb Haemost 7(Suppl 1):328-331
28. Weyand CM, Younge BR, Goronzy JJ 2008 T cells in arteritis and atherosclerosis. Curr Opin Lipidol 19:469-477
29. Wilson HM, Barker RN, Erwig LP 2009 Macrophages: promising targets for the treatment of atherosclerosis. Curr Vasc Pharmacol 7:234-243
30. Pállinger E, Csaba G 2008 A hormone map of human immune cells showing the presence of adrenocorticotropic hormone, triiodothyronine and endorphin in immunophenotyped white blood cells. Immunology 123:584-589 (Pubitemid 351280972)
31. Bernal J, Saukkonen-Bernal S 1983 Nuclear binding of triiodothyronine in human mononuclear cells, and lymphocytes in culture. Acta Endocrinol Suppl (Copenh) 251:16-20 (Pubitemid 13081267)
32. Duntas LH 2010 Selenium and the thyroid: a close-knit connection. J Clin Endocrinol Metab 95:5180-5188
33. Pearce EN, Bogazzi F, Martino E, Brogioni S, Pardini E, Pellegrini G, Parkes AB, Lazarus JH, Pinchera A, Braverman LE 2003 The prevalence of elevated serum C-reactive protein levels in inflammatory and noninflammatory thyroid disease. Thyroid 13:643-648 (Pubitemid 36993559)
34. Taddei S, Caraccio N, Virdis A, Dardano A, Versari D, Ghiadoni L, Ferrannini E, Salvetti A, Monzani F 2006 Low-grade systemic inflammation causes endothelial dysfunction in patients with Hashimoto's thyroiditis. J Clin Endocrinol Metab 91:5076-5082 (Pubitemid 44917353)
35. Erdal M, Sahin M, Hasimi A, Uckaya G, Kutlu M, Saglam K 2008 Trace element levels in Hashimoto thyroiditis patients with subclinical hypothyroidism. Biol Trace Elem Res 123:1-7
36. Karanikas G, Schuetz M, Kontur S, Duan H, Kommata S, Schoen R, Antoni A, Kletter K, Dudczak R, Willheim M 2008 No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis. Thyroid 18:7-12 (Pubitemid 351170446)
37. Effraimidis G, Tijssen JG, Wiersinga WM 2009 Discontinuation of smoking increases the risk for developing thyroid peroxidase antibodies and/or thyroglobulin antibodies: a prospective study. J Clin Endocrinol Metab 94:1324-1328
38. Pedersen IB, Laurberg P, Knudsen N, Jørgensen T, Perrild H, Ovesen L, Rasmussen LB 2008 Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population study. Eur J Endocrinol 158:367-373 (Pubitemid 351405002)