Cardiac progenitor cells for heart repair

Cell Death Discovery

Volumn 2, Issue 1, 2016, Pages

  Le, Tyl ^a,b   Chong, Jjh ^a,b,c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b WESTMEAD HOSPITAL   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85006234488     PISSN: None     EISSN: 20587716     Source Type: Journal    
DOI: 10.1038/cddiscovery.2016.52     Document Type: Review

References (27)

1. Anversa P, Kajstura J. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res 1998; 83: 1–14.
2. Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabe-Heider F, Walsh S et al. Evidence for cardiomyocyte renewal in humans. Science 2009; 324: 98–102.
3. Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD et al. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med 2007; 13: 970–974.
4. Senyo SE, Steinhauser ML, Pizzimenti CL, Yang VK, Cai L, Wang M et al. Mammalian heart renewal by pre-existing cardiomyocytes. Nature 2013; 493: 433–436.
5. Bearzi C, Rota M, Hosoda T, Tillmanns J, Nascimbene A, De Angelis A et al. Human cardiac stem cells. Proc Natl Acad Sci USA 2007; 104: 14068–14073.
6. Chong JJH, Chandrakanthan V, Xaymardan M, Asli NS, Li J, Ahmed I et al. Adult cardiac-resident msc-like stem cells with a proepicardial origin. Cell Stem Cell 2011; 9: 527–540.
7. Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y et al. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 2003; 100: 12313–12318.
8. Martin CM, Meeson AP, Robertson SM, Hawke TJ, Richardson JA, Bates S et al. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Dev Biol 2004; 265: 262–275.
9. Laugwitz KL, Moretti A, Lam J, Gruber P, Chen Y, Woodard S et al. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 2005; 433: 647–653.
10. Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009; 120: 1075–1083, 7 p following 83.
11. Ge Z, Lai S, Le TYL, dos Remedios C, Chong JJH. Cardiac stem cells: translation to human studies. Biophys Rev 2015; 7: 127–139.
12. Chong JJ, Forte E, Harvey RP. Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells. Stem Cell Res 2014; 13 (3 Pt B): 592–614.
13. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114: 763–776.
14. Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, Ikram S et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 2011; 378: 1847–1857.
15. Bolli R, Tang XL, Sanganalmath SK, Rimoldi O, Mosna F, Abdel-Latif A et al. Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy. Circulation 2013; 128: 122–131.
16. The Lancet E. Expression of concern: the SCIPIO trial. Lancet 2014; 383: 1279.
17. Messina E, De Angelis L, Frati G, Morrone S, Chimenti S, Fiordaliso F et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 2004; 95: 911–921.
18. Li TS, Cheng K, Malliaras K, Smith RR, Zhang Y, Sun B et al. Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 2012; 59: 942–953.
19. Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D et al. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 2012; 379: 895–904.
20. Weinberger F, Mehrkens D, Friedrich FW, Stubbendorff M, Hua X, Muller JC et al. Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart. Circ Res 2012; 110: 1303–1310.
21. Engleka KA, Manderfield LJ, Brust RD, Li L, Cohen A, Dymecki SM et al. Islet1 derivatives in the heart are of both neural crest and second heart field origin. Circ Res 2012; 110: 922–926.
22. van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC et al. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature 2014; 509: 337–341.
23. Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S et al. Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun 2015; 6: 8701.
24. Chong JJH, Reinecke H, Iwata M, Torok-Storb B, Stempien-Otero A, Murry CE. Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart. Stem Cells Dev 2013; 22: 1932–1943.
25. Gnecchi M, Zhang Z, Ni A, Dzau VJ. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 2008; 103: 1204–1219.
26. Ellison GM, Vicinanza C, Smith AJ, Aquila I, Leone A, Waring CD et al. Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell 2013; 154: 827–842.
27. Furtado MB, Costa MW, Pranoto EA, Salimova E, Pinto AR, Lam NT et al. Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair. Circ Res 2014; 114: 1422–1434.