-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel, R., J. Ma, Z. Zou, and A. Jemal . 2014. Cancer statistics, 2014. CA Cancer J. Clin. 64:9-29.
-
(2014)
CA Cancer J. Clin.
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
2
-
-
0035795581
-
Recent trends in cutaneous melanoma incidence among whites in the United States
-
Jemal, A., S. S. Devesa, P. Hartge, and M. A. Tucker . 2001. Recent trends in cutaneous melanoma incidence among whites in the United States. J. Natl Cancer Inst. 93:678-683.
-
(2001)
J. Natl Cancer Inst.
, vol.93
, pp. 678-683
-
-
Jemal, A.1
Devesa, S.S.2
Hartge, P.3
Tucker, M.A.4
-
3
-
-
39149104690
-
Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
-
Korn, E. L., P. Y. Liu, S. J. Lee, J. A. Chapman, D. Niedzwiecki, V. J. Suman, et al. 2008. Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. J. Clin. Oncol. 26:527-534.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 527-534
-
-
Korn, E.L.1
Liu, P.Y.2
Lee, S.J.3
Chapman, J.A.4
Niedzwiecki, D.5
Suman, V.J.6
-
4
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies, H., G. R. Bignell, C. Cox, P. Stephens, S. Edkins, S. Clegg, et al. 2002. Mutations of the BRAF gene in human cancer. Nature 417:949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
5
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman, P. B., A. Hauschild, C. Robert, J. B. Haanen, P. Ascierto, J. Larkin, et al. 2011. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364:2507-2516.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
6
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild, A., J. J. Grob, L. V. Demidov, T. Jouary, R. Gutzmer, M. Millward, et al. 2012. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 380:358-365.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
Jouary, T.4
Gutzmer, R.5
Millward, M.6
-
7
-
-
84863673204
-
Improved survival with MEK inhibition in BRAF-mutated melanoma
-
Flaherty, K. T., C. Robert, P. Hersey, P. Nathan, C. Garbe, M. Milhem, et al. 2012. Improved survival with MEK inhibition in BRAF-mutated melanoma. N. Engl. J. Med. 367:107-114.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 107-114
-
-
Flaherty, K.T.1
Robert, C.2
Hersey, P.3
Nathan, P.4
Garbe, C.5
Milhem, M.6
-
8
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
Flaherty, K. T., J. R. Infante, A. Daud, R. Gonzalez, R. F. Kefford, J. Sosman, et al. 2012. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N. Engl. J. Med. 367:1694-1703.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
Gonzalez, R.4
Kefford, R.F.5
Sosman, J.6
-
9
-
-
84856988252
-
Frequency of mutations associated with targeted therapy in malignant melanoma patients
-
abstr 8597.
-
Cheng, S., P. Chu, M. Hinshaw, K. Smith, J. Maize, and A. Sferruzza . 2011. Frequency of mutations associated with targeted therapy in malignant melanoma patients. J. Clin. Oncol. 29(Suppl.):abstr 8597.
-
(2011)
J. Clin. Oncol.
, vol.29
-
-
Cheng, S.1
Chu, P.2
Hinshaw, M.3
Smith, K.4
Maize, J.5
Sferruzza, A.6
-
10
-
-
0023270567
-
A new member of the immunoglobulin superfamily-CTLA-4
-
Brunet, J. F., F. Denizot, M. F. Luciani, M. Roux-Dosseto, M. Suzan, M. G. Mattei, et al. 1987. A new member of the immunoglobulin superfamily-CTLA-4. Nature 328:267-270.
-
(1987)
Nature
, vol.328
, pp. 267-270
-
-
Brunet, J.F.1
Denizot, F.2
Luciani, M.F.3
Roux-Dosseto, M.4
Suzan, M.5
Mattei, M.G.6
-
11
-
-
0023820250
-
A differential molecular biology search for genes preferentially expressed in functional T lymphocytes: the CTLA genes
-
Brunet, J. F., F. Denizot, and P. Golstein . 1988. A differential molecular biology search for genes preferentially expressed in functional T lymphocytes: the CTLA genes. Immunol. Rev. 103:21-36.
-
(1988)
Immunol. Rev.
, vol.103
, pp. 21-36
-
-
Brunet, J.F.1
Denizot, F.2
Golstein, P.3
-
12
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel, M. F., and J. P. Allison . 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459-465.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
13
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
Ribas, A., L. H. Camacho, G. Lopez-Berestein, D. Pavlov, C. A. Bulanhagui, R. Millham, et al. 2005. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675, 206. J. Clin. Oncol. 23:8968-8977.
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
Pavlov, D.4
Bulanhagui, C.A.5
Millham, R.6
-
14
-
-
61449090474
-
Phase I/II trial of tremelimumab in patients with metastatic melanoma
-
Camacho, L. H., S. Antonia, J. Sosman, J. M. Kirkwood, T. F. Gajewski, B. Redman, et al. 2009. Phase I/II trial of tremelimumab in patients with metastatic melanoma. J. Clin. Oncol. 27:1075-1081.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1075-1081
-
-
Camacho, L.H.1
Antonia, S.2
Sosman, J.3
Kirkwood, J.M.4
Gajewski, T.F.5
Redman, B.6
-
15
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas, A., R. Kefford, M. A. Marshall, C. J. Punt, J. B. Haanen, M. Marmol, et al. 2013. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J. Clin. Oncol. 31:616-622.
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
-
16
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F. S., S. J. O'Day, D. F. McDermott, R. W. Weber, J. A. Sosman, J. B. Haanen, et al. 2010. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363:711-723.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
17
-
-
33846465547
-
Immunostimulatory monoclonal antibodies for cancer therapy
-
Melero, I., S. Hervas-Stubbs, M. Glennie, D. M. Pardoll, and L. Chen . 2007. Immunostimulatory monoclonal antibodies for cancer therapy. Nat. Rev. Cancer 7:95-106.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 95-106
-
-
Melero, I.1
Hervas-Stubbs, S.2
Glennie, M.3
Pardoll, D.M.4
Chen, L.5
-
18
-
-
78449258549
-
Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy
-
Hoos, A., R. Ibrahim, A. Korman, K. Abdallah, D. Berman, V. Shahabi, et al. 2010. Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy. Semin. Oncol. 37:533-546.
-
(2010)
Semin. Oncol.
, vol.37
, pp. 533-546
-
-
Hoos, A.1
Ibrahim, R.2
Korman, A.3
Abdallah, K.4
Berman, D.5
Shahabi, V.6
-
19
-
-
78449243489
-
Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade
-
Weber, J. 2010. Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade. Semin. Oncol. 37:430-439.
-
(2010)
Semin. Oncol.
, vol.37
, pp. 430-439
-
-
Weber, J.1
-
20
-
-
78449249018
-
Ipilimumab: unleashing the power of the immune system through CTLA-4 blockade
-
Boasberg, P., O. Hamid, and S. O'Day . 2010. Ipilimumab: unleashing the power of the immune system through CTLA-4 blockade. Semin. Oncol. 37:440-449.
-
(2010)
Semin. Oncol.
, vol.37
, pp. 440-449
-
-
Boasberg, P.1
Hamid, O.2
O'Day, S.3
-
21
-
-
40949116644
-
Novel therapies targeting the immune system: CTLA4 blockade with tremelimumab (CP-675,206), a fully human monoclonal antibody
-
Camacho, L. H. 2008. Novel therapies targeting the immune system: CTLA4 blockade with tremelimumab (CP-675, 206), a fully human monoclonal antibody. Expert Opin. Investig. Drugs 17:371-385.
-
(2008)
Expert Opin. Investig. Drugs
, vol.17
, pp. 371-385
-
-
Camacho, L.H.1
-
22
-
-
35148900936
-
Three decades of evolving treatment for melanoma: no improvement in survival?
-
abstr 7511.
-
Young, S. E., A. E. Giuliano, and D. L. Morton . 2005. Three decades of evolving treatment for melanoma: no improvement in survival? J. Clin. Oncol. 23(Suppl.):abstr 7511.
-
(2005)
J. Clin. Oncol.
, vol.23
-
-
Young, S.E.1
Giuliano, A.E.2
Morton, D.L.3
-
23
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert, C., L. Thomas, I. Bondarenko, S. O'Day, J. Weber, C. Garbe, et al. 2011. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364:2517-2526.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
-
24
-
-
77955256254
-
Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study
-
O'Day, S. J., M. Maio, V. Chiarion-Sileni, T. F. Gajewski, H. Pehamberger, I. N. Bondarenko, et al. 2010. Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study. Ann. Oncol. 21:1712-1717.
-
(2010)
Ann. Oncol.
, vol.21
, pp. 1712-1717
-
-
O'Day, S.J.1
Maio, M.2
Chiarion-Sileni, V.3
Gajewski, T.F.4
Pehamberger, H.5
Bondarenko, I.N.6
-
25
-
-
84880310548
-
Four-year survival rates for patients with metastatic melanoma who received ipilimumab in phase II clinical trials
-
Wolchok, J. D., J. S. Weber, M. Maio, B. Neyns, K. Harmankaya, K. Chin, et al. 2013. Four-year survival rates for patients with metastatic melanoma who received ipilimumab in phase II clinical trials. Ann. Oncol. 24:2174-2180.
-
(2013)
Ann. Oncol.
, vol.24
, pp. 2174-2180
-
-
Wolchok, J.D.1
Weber, J.S.2
Maio, M.3
Neyns, B.4
Harmankaya, K.5
Chin, K.6
-
26
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
-
Wolchok, J. D., B. Neyns, G. Linette, S. Negrier, J. Lutzky, L. Thomas, et al. 2010. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol. 11:155-164.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
Negrier, S.4
Lutzky, J.5
Thomas, L.6
-
27
-
-
69949095926
-
A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma
-
Weber, J., J. A. Thompson, O. Hamid, D. Minor, A. Amin, I. Ron, et al. 2009. A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma. Clin. Cancer Res. 15:5591-5598.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5591-5598
-
-
Weber, J.1
Thompson, J.A.2
Hamid, O.3
Minor, D.4
Amin, A.5
Ron, I.6
-
28
-
-
84890312714
-
Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in metastatic or locally advanced, unresectable melanoma
-
abstr LBA24.
-
Schadendorf, D., F. S. Hodi, C. Robert, J. S. Weber, K. Margolin, and O. Hamid, et al. 2013. Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in metastatic or locally advanced, unresectable melanoma. Eur. J. Cancer 49(Suppl. 3):abstr LBA24.
-
(2013)
Eur. J. Cancer
, vol.49
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
Weber, J.S.4
Margolin, K.5
Hamid, O.6
-
29
-
-
73149092567
-
Guidelines for the evaluation of immune therapy in solid tumors: immune-related response criteria
-
Wolchok, J. D., A. Hoos, S. O'Day, J. S. Weber, O. Hamid, C. Lebbé, et al. 2009. Guidelines for the evaluation of immune therapy in solid tumors: immune-related response criteria. Clin. Cancer Res. 15:7412-7420.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
Weber, J.S.4
Hamid, O.5
Lebbé, C.6
-
30
-
-
84856008240
-
Ipilimumab safety profile: summary of findings from completed trials in advanced melanoma
-
abstr 8583.
-
Ibrahim, R., D. Berman, de Pril V., R. W. Humphrey, T. Chen, and M. Messina, et al. 2011. Ipilimumab safety profile: summary of findings from completed trials in advanced melanoma. J. Clin. Oncol. 29(Suppl.):abstr 8583.
-
(2011)
J. Clin. Oncol.
, vol.29
-
-
Ibrahim, R.1
Berman, D.2
de Pril, V.3
Humphrey, R.W.4
Chen, T.5
Messina, M.6
-
31
-
-
84891046707
-
Time to onset and resolution of immune-related adverse events associated with ipilimumab therapy in patients with advanced melanoma
-
Presented at the Perspectives in Melanoma XIV; 17-18 September 2010; Amsterdam, The Netherlands. Abstract P-0004.
-
Dummer R ., M. Maio., O. Hamid, S. J. O'Day, J. Richards, and J. D. Wolchok, et al. 2010. Time to onset and resolution of immune-related adverse events associated with ipilimumab therapy in patients with advanced melanoma. Presented at the Perspectives in Melanoma XIV; 17-18 September 2010; Amsterdam, The Netherlands. Abstract P-0004.
-
(2010)
-
-
Dummer, R.M.M.1
Hamid, O.2
O'Day, S.J.3
Richards, J.4
Wolchok, J.D.5
-
32
-
-
84929871811
-
Ipilimumab US prescribing information: risk evaluation and mitigation strategy
-
(accessed on 12 September 2011).
-
Ipilimumab US prescribing information: risk evaluation and mitigation strategy. Available at http://www.yervoy.com/hcp/rems.aspx (accessed on 12 September 2011).
-
-
-
-
33
-
-
34147188180
-
Transient hypophysitis after cytotoxic T lymphocyte-associated antigen 4 (CTLA4) blockade
-
Shaw, S. A., L. H. Camacho, I. E. McCutcheon, and S. G. Waguespack . 2007. Transient hypophysitis after cytotoxic T lymphocyte-associated antigen 4 (CTLA4) blockade. J. Clin. Endocrinol. Metab. 92:1201-1202.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 1201-1202
-
-
Shaw, S.A.1
Camacho, L.H.2
McCutcheon, I.E.3
Waguespack, S.G.4
-
35
-
-
84990198858
-
Common terminology criteria for adverse events
-
Version 3.0, DCTD, NCI, NIH, DHHS. (accessed 12 September 2011).
-
Cancer Therapy Evaluation Program (CTEP). Common terminology criteria for adverse events, Version 3.0, DCTD, NCI, NIH, DHHS. Available at http://ctep.cancer.gov (accessed 12 September 2011).
-
-
-
-
36
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
Postow, M. A., M. K. Callahan, C. A. Barker, Y. Yamada, J. Yuan, S. Kitano, et al. 2012. Immunologic correlates of the abscopal effect in a patient with melanoma. N. Engl. J. Med. 366:925-931.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
Yamada, Y.4
Yuan, J.5
Kitano, S.6
-
37
-
-
85006190931
-
Phase 3 trial in subjects with metastatic melanoma comparing 3 mg/kg ipilimumab versus 10 mg/kg ipilimumab
-
ClinicalTrials.gov. . (accessed 12 March 2014).
-
ClinicalTrials.gov. 2012. Phase 3 trial in subjects with metastatic melanoma comparing 3 mg/kg ipilimumab versus 10 mg/kg ipilimumab. Available at http://www.clinicaltrials.gov/ct2/show/NCT01515189 (accessed 12 March 2014).
-
(2012)
-
-
-
38
-
-
33747878218
-
Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma
-
Maker, A. V., J. C. Yang, R. M. Sherry, S. L. Topalian, U. S. Kammula, R. E. Royal, et al. 2006. Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma. J. Immunother. 29:455-463.
-
(2006)
J. Immunother.
, vol.29
, pp. 455-463
-
-
Maker, A.V.1
Yang, J.C.2
Sherry, R.M.3
Topalian, S.L.4
Kammula, U.S.5
Royal, R.E.6
-
39
-
-
84877093633
-
Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control
-
Robert, C., D. Schadendorf, M. Messina, F. S. Hodi, S. O'Day, and MDX investigators. 2013. Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control. Clin. Cancer Res. 19:2232-2239.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 2232-2239
-
-
Robert, C.1
Schadendorf, D.2
Messina, M.3
Hodi, F.S.4
O'Day, S.5
-
40
-
-
85006215326
-
-
(accessed 10 December 2013).
-
National Comprehensive Cancer Network. Melanoma. Vol. 3.2014. Available at http://www.nccn.org/professionals/physician_gls/PDF/melanoma.pdf (accessed 10 December 2013).
-
(2014)
Melanoma
, vol.3
-
-
-
41
-
-
70349680756
-
Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma
-
Ribas, A., B. Comin-Anduix, B. Chmielowski, J. Jalil, P. de la Rocha, T. A. McCannel, et al. 2009. Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma. Clin. Cancer Res. 15:6267-6276.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6267-6276
-
-
Ribas, A.1
Comin-Anduix, B.2
Chmielowski, B.3
Jalil, J.4
de la Rocha, P.5
McCannel, T.A.6
-
42
-
-
84875785905
-
Hepatotoxicity with combination of vemurafenib and ipilimumab
-
Ribas, A., F. S. Hodi, M. Callahan, C. Konto, and J. Wolchok . 2013. Hepatotoxicity with combination of vemurafenib and ipilimumab. N. Engl. J. Med. 368:1365-1366.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1365-1366
-
-
Ribas, A.1
Hodi, F.S.2
Callahan, M.3
Konto, C.4
Wolchok, J.5
-
43
-
-
84877043331
-
Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery
-
Mathew, M., M. Tam, P. A. Ott, A. C. Pavlick, S. C. Rush, B. R. Donahue, et al. 2013. Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery. Melanoma Res. 23:191-195.
-
(2013)
Melanoma Res.
, vol.23
, pp. 191-195
-
-
Mathew, M.1
Tam, M.2
Ott, P.A.3
Pavlick, A.C.4
Rush, S.C.5
Donahue, B.R.6
-
44
-
-
84864559660
-
Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival
-
Knisely, J. P., J. B. Yu, J. Flanigan, M. Sznol, H. M. Kluger, and V. L. Chiang . 2012. Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival. J. Neurosurg. 117:227-233.
-
(2012)
J. Neurosurg.
, vol.117
, pp. 227-233
-
-
Knisely, J.P.1
Yu, J.B.2
Flanigan, J.3
Sznol, M.4
Kluger, H.M.5
Chiang, V.L.6
-
45
-
-
84904216679
-
Ipilimumab and radiation therapy for melanoma brain metastases
-
Silk, A. W., M. F. Bassetti, B. T. West, C. I. Tsien, and C. D. Lao . 2013. Ipilimumab and radiation therapy for melanoma brain metastases. Cancer Med. 2:899-906.
-
(2013)
Cancer Med.
, vol.2
, pp. 899-906
-
-
Silk, A.W.1
Bassetti, M.F.2
West, B.T.3
Tsien, C.I.4
Lao, C.D.5
-
46
-
-
84893877031
-
Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma
-
Barker, C. A., M. A. Postow, S. A. Khan, K. Beal, P. K. Parhar, Y. Yamada, et al. 2013. Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma. Cancer Immunol. Res. 1:92-98.
-
(2013)
Cancer Immunol. Res.
, vol.1
, pp. 92-98
-
-
Barker, C.A.1
Postow, M.A.2
Khan, S.A.3
Beal, K.4
Parhar, P.K.5
Yamada, Y.6
-
47
-
-
84860446616
-
Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial
-
Margolin, K., M. S. Ernstoff, O. Hamid, D. Lawrence, D. McDermott, I. Puzanov, et al. 2012. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol. 13:459-465.
-
(2012)
Lancet Oncol.
, vol.13
, pp. 459-465
-
-
Margolin, K.1
Ernstoff, M.S.2
Hamid, O.3
Lawrence, D.4
McDermott, D.5
Puzanov, I.6
-
48
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
Dong, H., S. E. Strome, D. R. Salomao, H. Tamura, F. Hirano, D. B. Flies, et al. 2002. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8:793-800.
-
(2002)
Nat. Med.
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
49
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel, T. J., S. Wei, H. Dong, X. Alvarez, P. Cheng, P. Mottram, et al. 2003. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat. Med. 9:562-567.
-
(2003)
Nat. Med.
, vol.9
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
50
-
-
33645736792
-
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
Thompson, R. H., S. M. Kuntz, B. C. Leibovich, H. Dong, C. M. Lohse, W. S. Webster, et al. 2006. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res. 66:3381-3385.
-
(2006)
Cancer Res.
, vol.66
, pp. 3381-3385
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
Dong, H.4
Lohse, C.M.5
Webster, W.S.6
-
51
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer, J. R., C. G. Drake, I. Wollner, J. D. Powderly, J. Picus, W. H. Sharfman, et al. 2010. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28:3167-3175.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
52
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano, F., K. Kaneko, H. Tamura, H. Dong, S. Wang, M. Ichikawa, et al. 2005. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res. 65:1089-1096.
-
(2005)
Cancer Res.
, vol.65
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
-
54
-
-
84895904745
-
Mitigating the toxic effects of anticancer immunotherapy
-
Ganghadar, T. C., and R. H. Vonderheide . 2014. Mitigating the toxic effects of anticancer immunotherapy. Nat. Rev. Clin. Oncol. 11:91-99.
-
(2014)
Nat. Rev. Clin. Oncol.
, vol.11
, pp. 91-99
-
-
Ganghadar, T.C.1
Vonderheide, R.H.2
-
55
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian, S. L., M. Sznol, D. F. McDermott, H. M. Kluger, R. D. Carvajal, W. H. Sharfman, et al. 2014. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J. Clin. Oncol. 32:1020-1030.
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
56
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid, O., C. Robert, A. Daud, F. S. Hodi, W. J. Hwu, R. Kefford, et al. 2013. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N. Engl. J. Med. 369:134-144.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
57
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
Robert, C., A. Ribas, J. D. Wolchok, F. S. Hodi, O. Hamid, R. Kefford, et al. 2014. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 384:1109-1117.
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
-
58
-
-
84907543029
-
Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL)
-
abstr LBA9000.
-
Ribas, A., F. S. Hodi, R. Kefford, O. Hamid, A. Daud, and J. D. Wolchok, et al. 2014. Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL). J. Clin. Oncol. 32(Suppl. 5):abstr LBA9000.
-
(2014)
J. Clin. Oncol.
, vol.32
-
-
Ribas, A.1
Hodi, F.S.2
Kefford, R.3
Hamid, O.4
Daud, A.5
Wolchok, J.D.6
-
59
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok, J. D., H. Kluger, M. K. Callahan, M. A. Postow, N. A. Rizvi, A. M. Lesokhin, et al. 2013. Nivolumab plus ipilimumab in advanced melanoma. N. Engl. J. Med. 369:122-133.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
|