Sample size in clinical cardioprotection trials using myocardial salvage index, infarct size, or biochemical markers as endpoint

Journal of the American Heart Association

Volumn 5, Issue 3, 2015, Pages

  Engblom, Henrik ^a   Heiberg, Einar ^a,b   Erlinge, David ^a   Jensen, Svend Eggert ^c   Nordrehaug, Jan Erik ^d   Dubois Randé, Jean Luc ^e   Halvorsen, Sigrun ^f,g   Hoffmann, Pavel ^f   Koul, Sasha ^a   Carlsson, Marcus ^a   Atar, Dan ^f,g   Arheden, Hakan ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY OF BERGEN   (Norway)

^e HENRI MONDOR HOSPITAL   (France)

^f ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^g UNIVERSITY OF OSLO   (Norway)

Author keywords

Acute myocardial infarction; Biochemical markers; Cardioprotection; Myocardial salvage index; Sample size

Indexed keywords

BIOCHEMICAL MARKER; CREATINE KINASE MB; TROPONIN T; BIOLOGICAL MARKER;

ACUTE HEART INFARCTION; ARTICLE; CARDIOVASCULAR DISEASE ASSESSMENT; CARDIOVASCULAR MAGNETIC RESONANCE; EFFECT SIZE; HEART INFARCTION SIZE; HEART PROTECTION; HUMAN; MONTE CARLO METHOD; MULTICENTER STUDY (TOPIC); MYOCARDIAL SALVAGE INDEX; MYOCARDIUM AT RISK; NUCLEAR MAGNETIC RESONANCE SCANNER; OUTCOME VARIABLE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SAMPLE SIZE; STATISTICAL SIGNIFICANCE; ADVERSE EFFECTS; BIOASSAY; BLOOD; CARDIAC MUSCLE; CLINICAL TRIAL; COMPUTER SIMULATION; CONTROLLED STUDY; METABOLISM; MULTICENTER STUDY; MYOCARDIAL INFARCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; REPERFUSION INJURY; REPRODUCIBILITY; STATISTICAL BIAS; TIME FACTOR; TREATMENT OUTCOME;

BIAS (EPIDEMIOLOGY); BIOMARKERS; COMPUTER SIMULATION; CREATINE KINASE, MB FORM; ENDPOINT DETERMINATION; HUMANS; MAGNETIC RESONANCE IMAGING; MYOCARDIAL INFARCTION; MYOCARDIUM; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE OF TESTS; REPERFUSION INJURY; REPRODUCIBILITY OF RESULTS; SAMPLE SIZE; TIME FACTORS; TREATMENT OUTCOME; TROPONIN T;

EID: 85006186650     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002708     Document Type: Article

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