메뉴 건너뛰기




Volumn 39, Issue 3, 2017, Pages 245-253

Selection of epitopes from self-antigens for eliciting Th2 or Th1 activity in the treatment of autoimmune disease or cancer

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; ADALIMUMAB; CYCLOPHOSPHAMIDE; DACLIZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITOPE; ETANERCEPT; FINGOLIMOD; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NATALIZUMAB; RITUXIMAB; TRASTUZUMAB; VACCINE; AUTOANTIGEN;

EID: 85006172771     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-016-0596-7     Document Type: Review
Times cited : (15)

References (64)
  • 2
    • 84859941928 scopus 로고    scopus 로고
    • Therapeutic antibodies against cancer
    • PID: 22520975, vii
    • Adler MJ, Dimitrov DS (2012) Therapeutic antibodies against cancer. Hematol Oncol Clin North Am 26(3):447–481 vii
    • (2012) Hematol Oncol Clin North Am , vol.26 , Issue.3 , pp. 447-481
    • Adler, M.J.1    Dimitrov, D.S.2
  • 5
    • 84937946677 scopus 로고    scopus 로고
    • Oncogenic cancer/testis antigens: prime candidates for immunotherapy
    • PID: 26158218, Jun 30
    • Gjerstorff MF, Andersen MH, Ditzel HJ (2015) Jun 30 Oncogenic cancer/testis antigens: prime candidates for immunotherapy. Oncotarget 6(18):15772–15787
    • (2015) Oncotarget , vol.6 , Issue.18 , pp. 15772-15787
    • Gjerstorff, M.F.1    Andersen, M.H.2    Ditzel, H.J.3
  • 7
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • COI: 1:CAS:528:DC%2BC38Xjslersb4%3D, PID: 22419253, Mar 15
    • Fridman WH, Pagès F, Sautès-Fridman C, Galon J (2012) Mar 15 The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 12(4):298–306
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 298-306
    • Fridman, W.H.1    Pagès, F.2    Sautès-Fridman, C.3    Galon, J.4
  • 8
    • 0026147769 scopus 로고
    • Immunopathological recognition of autoantigens in multiple sclerosis
    • COI: 1:STN:280:DyaK3MzmvVKjsA%3D%3D
    • Bernard CC, de Rosbo NK (1991) Immunopathological recognition of autoantigens in multiple sclerosis. Acta Neurol (Napoli) 13(2):171–178
    • (1991) Acta Neurol (Napoli) , vol.13 , Issue.2 , pp. 171-178
    • Bernard, C.C.1    de Rosbo, N.K.2
  • 9
    • 84929299047 scopus 로고    scopus 로고
    • Zimmerman DH. Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC2MXotFWlt7c%3D, PID: 25787143
    • Rosenthal KS, Mikecz K, Steiner HL 3rd, Glant TT, Finnegan A, Carambula RE (2015) Zimmerman DH. Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis. Expert Rev Vaccines 14(6):891–908
    • (2015) Expert Rev Vaccines , vol.14 , Issue.6 , pp. 891-908
    • Rosenthal, K.S.1    Mikecz, K.2    Steiner, H.L.3    Glant, T.T.4    Finnegan, A.5    Carambula, R.E.6
  • 10
    • 1942507364 scopus 로고    scopus 로고
    • Detection of CD4+ autoreactive T cells in T1D using HLA class II tetramers
    • PID: 14679042
    • Reijonen H, Kwok WW, Nepom GT (2003) Detection of CD4+ autoreactive T cells in T1D using HLA class II tetramers. Ann N Y Acad Sci 1005:82–87
    • (2003) Ann N Y Acad Sci , vol.1005 , pp. 82-87
    • Reijonen, H.1    Kwok, W.W.2    Nepom, G.T.3
  • 11
    • 23944444890 scopus 로고    scopus 로고
    • IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
    • COI: 1:CAS:528:DC%2BD2MXosVarsr4%3D, PID: 16087714, Aug 15
    • Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR (2005) Aug 15 IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 202(4):473–477
    • (2005) J Exp Med , vol.202 , Issue.4 , pp. 473-477
    • Lennon, V.A.1    Kryzer, T.J.2    Pittock, S.J.3    Verkman, A.S.4    Hinson, S.R.5
  • 12
    • 84906313018 scopus 로고    scopus 로고
    • EAE is not a useful model for demyelinating disease
    • PID: 26265268
    • Behan PO, Chaudhuri A (2014) EAE is not a useful model for demyelinating disease. Mult Scler Relat Disord 3(5):565–574
    • (2014) Mult Scler Relat Disord , vol.3 , Issue.5 , pp. 565-574
    • Behan, P.O.1    Chaudhuri, A.2
  • 13
    • 84908365143 scopus 로고    scopus 로고
    • From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development
    • COI: 1:CAS:528:DC%2BC2cXhsV2nsbbO, PID: 25175979
    • Ben-Nun A, Kaushansky N, Kawakami N, Krishnamoorthy G, Berer K, Liblau R, Hohlfeld R, Wekerle H (2014) From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development. J Autoimmun 54:33–50
    • (2014) J Autoimmun , vol.54 , pp. 33-50
    • Ben-Nun, A.1    Kaushansky, N.2    Kawakami, N.3    Krishnamoorthy, G.4    Berer, K.5    Liblau, R.6    Hohlfeld, R.7    Wekerle, H.8
  • 14
    • 84907907834 scopus 로고    scopus 로고
    • Is the “3 + 3” dose-escalation phase I clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design
    • COI: 1:CAS:528:DC%2BC2cXhsFChu7%2FE, PID: 25037736, Sep 15
    • Rahma OE, Gammoh E, Simon RM, Khleif SN (2014) Sep 15 Is the “3 + 3” dose-escalation phase I clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design. Clin Cancer Res 20(18):4758–4767
    • (2014) Clin Cancer Res , vol.20 , Issue.18 , pp. 4758-4767
    • Rahma, O.E.1    Gammoh, E.2    Simon, R.M.3    Khleif, S.N.4
  • 15
    • 33746012881 scopus 로고    scopus 로고
    • Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
    • COI: 1:CAS:528:DC%2BD28XnslKhs7g%3D, PID: 16809734, Jul 1
    • Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, Verjee SS, Jones LA, Hershberg RM (2006) Jul 1 Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 24(19):3089–3094
    • (2006) J Clin Oncol , vol.24 , Issue.19 , pp. 3089-3094
    • Small, E.J.1    Schellhammer, P.F.2    Higano, C.S.3    Redfern, C.H.4    Nemunaitis, J.J.5    Valone, F.H.6    Verjee, S.S.7    Jones, L.A.8    Hershberg, R.M.9
  • 19
    • 84956890894 scopus 로고    scopus 로고
    • Algenpantucel-L immunotherapy in pancreatic adenocarcinoma
    • COI: 1:CAS:528:DC%2BC28XhslKmsL8%3D, PID: 26787078
    • Coveler AL, Rossi GR, Vahanian NN, Link C, Chiorean EG (2016) Algenpantucel-L immunotherapy in pancreatic adenocarcinoma. Immunotherapy 8(2):117–125
    • (2016) Immunotherapy , vol.8 , Issue.2 , pp. 117-125
    • Coveler, A.L.1    Rossi, G.R.2    Vahanian, N.N.3    Link, C.4    Chiorean, E.G.5
  • 20
    • 85016238236 scopus 로고    scopus 로고
    • http://investors.aduro.com/phoenix.zhtml?c=242043&p=irol-newsArticle&ID=2168543
  • 22
    • 84902079425 scopus 로고    scopus 로고
    • The HER2 peptide nelipepimut-S (E75) vaccine (NeuVax™) in breast cancer patients at risk for recurrence: correlation of immunologic data with clinical response
    • COI: 1:CAS:528:DC%2BC2cXpt1Srur0%3D, PID: 24896623
    • Schneble EJ, Berry JS, Trappey FA, Clifton GT, Ponniah S, Mittendorf E, Peoples GE (2014) The HER2 peptide nelipepimut-S (E75) vaccine (NeuVax™) in breast cancer patients at risk for recurrence: correlation of immunologic data with clinical response. Immunotherapy 6(5):519–531
    • (2014) Immunotherapy , vol.6 , Issue.5 , pp. 519-531
    • Schneble, E.J.1    Berry, J.S.2    Trappey, F.A.3    Clifton, G.T.4    Ponniah, S.5    Mittendorf, E.6    Peoples, G.E.7
  • 24
    • 84921742575 scopus 로고    scopus 로고
    • Tecemotide: an antigen-specific cancer immunotherapy
    • PID: 25483673
    • Wurz GT, Kao CJ, Wolf M, DeGregorio MW (2014) Tecemotide: an antigen-specific cancer immunotherapy. Hum Vaccin Immunother 10(11):3383–3393
    • (2014) Hum Vaccin Immunother , vol.10 , Issue.11 , pp. 3383-3393
    • Wurz, G.T.1    Kao, C.J.2    Wolf, M.3    DeGregorio, M.W.4
  • 25
    • 59849122181 scopus 로고    scopus 로고
    • The cancer vaccine roller coaster
    • COI: 1:CAS:528:DC%2BD1MXhs1CktrY%3D, PID: 19204689
    • Goldman B, DeFrancesco L (2009) The cancer vaccine roller coaster. Nat Biotechnol 27(2):129–139
    • (2009) Nat Biotechnol , vol.27 , Issue.2 , pp. 129-139
    • Goldman, B.1    DeFrancesco, L.2
  • 27
    • 0036141435 scopus 로고    scopus 로고
    • NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells
    • COI: 1:CAS:528:DC%2BD38XntV2htg%3D%3D, PID: 11782380, Jan 1
    • Zarour HM, Maillere B, Brusic V, Coval K, Williams E, Pouvelle-Moratille S, Castelli F, Land S, Bennouna J, Logan T, Kirkwood JM (2002) Jan 1 NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells. Cancer Res 62(1):213–218
    • (2002) Cancer Res , vol.62 , Issue.1 , pp. 213-218
    • Zarour, H.M.1    Maillere, B.2    Brusic, V.3    Coval, K.4    Williams, E.5    Pouvelle-Moratille, S.6    Castelli, F.7    Land, S.8    Bennouna, J.9    Logan, T.10    Kirkwood, J.M.11
  • 28
    • 19944430099 scopus 로고    scopus 로고
    • One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma
    • COI: 1:CAS:528:DC%2BD2MXlsFyrsQ%3D%3D, PID: 15661941, Feb 1
    • Mandic M, Castelli F, Janjic B, Almunia C, Andrade P, Gillet D, Brusic V, Kirkwood JM, Maillere B, Zarour HM (2005) Feb 1 One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma. J Immunol 174(3):1751–1759
    • (2005) J Immunol , vol.174 , Issue.3 , pp. 1751-1759
    • Mandic, M.1    Castelli, F.2    Janjic, B.3    Almunia, C.4    Andrade, P.5    Gillet, D.6    Brusic, V.7    Kirkwood, J.M.8    Maillere, B.9    Zarour, H.M.10
  • 31
    • 84868108564 scopus 로고    scopus 로고
    • A cancer vaccine induces expansion of NY-ESO-1-specific regulatory T cells in patients with advanced melanoma
    • COI: 1:CAS:528:DC%2BC38Xhs1yrtb7K, PID: 23110239
    • Ebert LM, MacRaild SE, Zanker D, Davis ID, Cebon J, Chen W (2012) A cancer vaccine induces expansion of NY-ESO-1-specific regulatory T cells in patients with advanced melanoma. PLoS One 7(10):e48424
    • (2012) PLoS One , vol.7 , Issue.10
    • Ebert, L.M.1    MacRaild, S.E.2    Zanker, D.3    Davis, I.D.4    Cebon, J.5    Chen, W.6
  • 32
    • 0033136779 scopus 로고    scopus 로고
    • Emergence of regulatory CD4+ T cell response to repetitive stimulation with antigen-presenting cells in vitro: implications in designing antigen-presenting cell-based tumor vaccines
    • COI: 1:CAS:528:DyaK1MXislGnsb8%3D, PID: 10228040, May 1
    • Chakraborty NG, Li L, Sporn JR, Kurtzman SH, Ergin MT, Mukherji B (1999) May 1 Emergence of regulatory CD4+ T cell response to repetitive stimulation with antigen-presenting cells in vitro: implications in designing antigen-presenting cell-based tumor vaccines. J Immunol 162(9):5576–5583
    • (1999) J Immunol , vol.162 , Issue.9 , pp. 5576-5583
    • Chakraborty, N.G.1    Li, L.2    Sporn, J.R.3    Kurtzman, S.H.4    Ergin, M.T.5    Mukherji, B.6
  • 33
    • 4444279152 scopus 로고    scopus 로고
    • Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma
    • COI: 1:CAS:528:DC%2BD2cXntVOht7o%3D, PID: 15336780
    • Chakraborty NG, Chattopadhyay S, Mehrotra S, Chhabra A, Mukherji B (2004) Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma. Hum Immunol 65(8):794–802
    • (2004) Hum Immunol , vol.65 , Issue.8 , pp. 794-802
    • Chakraborty, N.G.1    Chattopadhyay, S.2    Mehrotra, S.3    Chhabra, A.4    Mukherji, B.5
  • 34
    • 79953816808 scopus 로고    scopus 로고
    • Immunologic biomarkers as correlates of clinical response to cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC3MXit1Gqsb4%3D, PID: 21221967
    • Disis ML (2011) Immunologic biomarkers as correlates of clinical response to cancer immunotherapy. Cancer Immunol Immunother 60(3):433–442
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.3 , pp. 433-442
    • Disis, M.L.1
  • 35
    • 0037302519 scopus 로고    scopus 로고
    • Determinant spreading and tumor responses after peptide-based cancer immunotherapy
    • COI: 1:CAS:528:DC%2BD3sXltVGqsA%3D%3D, PID: 12547500
    • Ribas A, Timmerman JM, Butterfield LH, Economou JS (2003) Determinant spreading and tumor responses after peptide-based cancer immunotherapy. Trends Immunol 24(2):58–61
    • (2003) Trends Immunol , vol.24 , Issue.2 , pp. 58-61
    • Ribas, A.1    Timmerman, J.M.2    Butterfield, L.H.3    Economou, J.S.4
  • 37
    • 0036605567 scopus 로고    scopus 로고
    • Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines
    • COI: 1:CAS:528:DC%2BD38XkvF2mtr8%3D, PID: 12039923, Jun 1
    • Disis ML, Gooley TA, Rinn K, Davis D, Piepkorn M, Cheever MA, Knutson KL, Schiffman K (2002) Jun 1 Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines. J Clin Oncol 20(11):2624–2632
    • (2002) J Clin Oncol , vol.20 , Issue.11 , pp. 2624-2632
    • Disis, M.L.1    Gooley, T.A.2    Rinn, K.3    Davis, D.4    Piepkorn, M.5    Cheever, M.A.6    Knutson, K.L.7    Schiffman, K.8
  • 40
    • 0345060456 scopus 로고    scopus 로고
    • Immunization of cancer patients with HER-2/neu-derived peptides demonstrating high-affinity binding to multiple class II alleles
    • COI: 1:CAS:528:DC%2BD3sXpsVejtbw%3D, PID: 14654536, Nov 15
    • Salazar LG, Fikes J, Southwood S, Ishioka G, Knutson KL, Gooley TA, Schiffman K, Disis ML (2003) Nov 15 Immunization of cancer patients with HER-2/neu-derived peptides demonstrating high-affinity binding to multiple class II alleles. Clin Cancer Res 9(15):5559–5565
    • (2003) Clin Cancer Res , vol.9 , Issue.15 , pp. 5559-5565
    • Salazar, L.G.1    Fikes, J.2    Southwood, S.3    Ishioka, G.4    Knutson, K.L.5    Gooley, T.A.6    Schiffman, K.7    Disis, M.L.8
  • 41
    • 54249086700 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-2 is a target for the immunomodulation of breast cancer
    • COI: 1:CAS:528:DC%2BD1cXht1Cmsb3F, PID: 18922913, Oct 15
    • Park KH, Gad E, Goodell V, Dang Y, Wild T, Higgins D, Fintak P, Childs J, Dela Rosa C, Disis ML (2008) Oct 15 Insulin-like growth factor-binding protein-2 is a target for the immunomodulation of breast cancer. Cancer Res 68(20):8400–8409
    • (2008) Cancer Res , vol.68 , Issue.20 , pp. 8400-8409
    • Park, K.H.1    Gad, E.2    Goodell, V.3    Dang, Y.4    Wild, T.5    Higgins, D.6    Fintak, P.7    Childs, J.8    Dela Rosa, C.9    Disis, M.L.10
  • 42
    • 84901263463 scopus 로고    scopus 로고
    • Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity
    • COI: 1:CAS:528:DC%2BC2cXnvF2hs7Y%3D, PID: 24778415, May 15
    • Cecil DL, Holt GE, Park KH, Gad E, Rastetter L, Childs J, Higgins D, Disis ML (2014) May 15 Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity. Cancer Res 74(10):2710–2718
    • (2014) Cancer Res , vol.74 , Issue.10 , pp. 2710-2718
    • Cecil, D.L.1    Holt, G.E.2    Park, K.H.3    Gad, E.4    Rastetter, L.5    Childs, J.6    Higgins, D.7    Disis, M.L.8
  • 44
    • 0025819555 scopus 로고
    • Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides
    • COI: 1:CAS:528:DyaK3MXksVOls7w%3D, PID: 1827917, May 15
    • Milich DR, McLachlan A, Raney AK, Houghten R, Thornton GB, Maruyama T, Hughes JL, Jones JE (1991) May 15 Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides. Proc Natl Acad Sci U S A 88(10):4348–4352
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.10 , pp. 4348-4352
    • Milich, D.R.1    McLachlan, A.2    Raney, A.K.3    Houghten, R.4    Thornton, G.B.5    Maruyama, T.6    Hughes, J.L.7    Jones, J.E.8
  • 48
    • 0037310556 scopus 로고    scopus 로고
    • Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage
    • COI: 1:CAS:528:DC%2BD3sXhtlSiu7Y%3D, PID: 12525380
    • Meyer O, Labarre C, Dougados M, Goupille P, Cantagrel A, Dubois A, Nicaise-Roland P, Sibilia J, Combe B (2003) Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage. Ann Rheum Dis 62(2):120–126
    • (2003) Ann Rheum Dis , vol.62 , Issue.2 , pp. 120-126
    • Meyer, O.1    Labarre, C.2    Dougados, M.3    Goupille, P.4    Cantagrel, A.5    Dubois, A.6    Nicaise-Roland, P.7    Sibilia, J.8    Combe, B.9
  • 49
    • 0027217907 scopus 로고
    • The cytokeratin filament-aggregating protein filaggrin is the target of the so-called “antikeratin antibodies,” autoantibodies specific for rheumatoid arthritis
    • COI: 1:CAS:528:DyaK3sXmsVOrtbc%3D, PID: 7690781
    • Simon M, Girbal E, Sebbag M, Gomès-Daudrix V, Vincent C, Salama G, Serre G (1993) The cytokeratin filament-aggregating protein filaggrin is the target of the so-called “antikeratin antibodies,” autoantibodies specific for rheumatoid arthritis. J Clin Invest 92(3):1387–1393
    • (1993) J Clin Invest , vol.92 , Issue.3 , pp. 1387-1393
    • Simon, M.1    Girbal, E.2    Sebbag, M.3    Gomès-Daudrix, V.4    Vincent, C.5    Salama, G.6    Serre, G.7
  • 50
    • 84884407695 scopus 로고    scopus 로고
    • Different amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis
    • PID: 24060405, Sep 23
    • Turunen S, Koivula MK, Melkko J, Alasaarela E, Lehenkari P, Risteli J (2013) Sep 23 Different amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis. J Transl Med 11:224
    • (2013) J Transl Med , vol.11 , pp. 224
    • Turunen, S.1    Koivula, M.K.2    Melkko, J.3    Alasaarela, E.4    Lehenkari, P.5    Risteli, J.6
  • 51
    • 84931459709 scopus 로고    scopus 로고
    • Immune tolerance induction with multiepitope peptide derived from citrullinated autoantigens attenuates arthritis manifestations in adjuvant arthritis rats
    • COI: 1:CAS:528:DC%2BC2MXpsFOmurY%3D, PID: 25964493, Jun 15
    • Gertel S, Serre G, Shoenfeld Y, Amital H (2015) Jun 15 Immune tolerance induction with multiepitope peptide derived from citrullinated autoantigens attenuates arthritis manifestations in adjuvant arthritis rats. J Immunol 194(12):5674–5680
    • (2015) J Immunol , vol.194 , Issue.12 , pp. 5674-5680
    • Gertel, S.1    Serre, G.2    Shoenfeld, Y.3    Amital, H.4
  • 55
    • 0036172037 scopus 로고    scopus 로고
    • Influence of a dominant cryptic epitope on autoimmune T cell tolerance
    • COI: 1:CAS:528:DC%2BD38XhtVygurg%3D, PID: 11812995
    • Anderton SM, Viner NJ, Matharu P, Lowrey PA, Wraith DC (2002) Influence of a dominant cryptic epitope on autoimmune T cell tolerance. Nat Immunol 3(2):175–181
    • (2002) Nat Immunol , vol.3 , Issue.2 , pp. 175-181
    • Anderton, S.M.1    Viner, N.J.2    Matharu, P.3    Lowrey, P.A.4    Wraith, D.C.5
  • 56
    • 0033592853 scopus 로고    scopus 로고
    • Abundant empty class II MHC molecules on the surface of immature dendritic cells
    • COI: 1:CAS:528:DC%2BD3cXhtFaktA%3D%3D, PID: 10611336, Dec 21
    • Santambrogio L, Sato AK, Fischer FR, Dorf ME, Stern LJ (1999) Dec 21 Abundant empty class II MHC molecules on the surface of immature dendritic cells. Proc Natl Acad Sci U S A 96(26):15050–15055
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.26 , pp. 15050-15055
    • Santambrogio, L.1    Sato, A.K.2    Fischer, F.R.3    Dorf, M.E.4    Stern, L.J.5
  • 57
    • 0032821774 scopus 로고    scopus 로고
    • Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10
    • COI: 1:CAS:528:DyaK1MXmvFaqu7o%3D, PID: 10508180
    • Burkhart C, Liu GY, Anderton SM, Metzler B, Wraith DC (1999) Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10. Int Immunol 11(10):1625–1634
    • (1999) Int Immunol , vol.11 , Issue.10 , pp. 1625-1634
    • Burkhart, C.1    Liu, G.Y.2    Anderton, S.M.3    Metzler, B.4    Wraith, D.C.5
  • 58
    • 68149100383 scopus 로고    scopus 로고
    • Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells
    • PID: 19635862, Aug 3
    • Gabrysová L, Nicolson KS, Streeter HB, Verhagen J, Sabatos-Peyton CA, Morgan DJ, Wraith DC (2009) Aug 3 Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells. J Exp Med 206(8):1755–1767
    • (2009) J Exp Med , vol.206 , Issue.8 , pp. 1755-1767
    • Gabrysová, L.1    Nicolson, K.S.2    Streeter, H.B.3    Verhagen, J.4    Sabatos-Peyton, C.A.5    Morgan, D.J.6    Wraith, D.C.7
  • 62
    • 85080826538 scopus 로고    scopus 로고
    • Novel methods for addressing immunogenicity in therapeutic enzymes
    • Cousens LP, Moise L, De Groot AS. . In A. Rosenberg, B. Demeule (eds) . American Association of Pharmaceutical Scientists in the Pharmaceutical Sciences Series 9
    • Cousens LP, Moise L, De Groot AS. Novel methods for addressing immunogenicity in therapeutic enzymes. In A. Rosenberg, B. Demeule (eds) Biobetters, AAPS Advances. American Association of Pharmaceutical Scientists 2015 in the Pharmaceutical Sciences Series 9
    • (2015) Biobetters, AAPS Advances


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.