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Volumn 2, Issue 1, 2014, Pages

Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis

Author keywords

Experimental autoimmune encephalomyelitis; Gliosis; Multiple sclerosis; Neurodegeneration; Remyelination

Indexed keywords


EID: 85005878483     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-1-84     Document Type: Article
Times cited : (27)

References (39)
  • 1
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A: Multiple sclerosis. Lancet 2008, 372: 1502-1517. 10.1016/S0140-6736(08)61620-7
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 2
    • 33644974688 scopus 로고    scopus 로고
    • Secondary progressive multiple sclerosis: current knowledge and future challenges
    • Rovaris M, Confavreux C, Furlan R, Kappos L, Comi G, Filippi M: Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol 2006, 5: 343-354. 10.1016/S1474-4422(06)70410-0
    • (2006) Lancet Neurol , vol.5 , pp. 343-354
    • Rovaris, M.1    Confavreux, C.2    Furlan, R.3    Kappos, L.4    Comi, G.5    Filippi, M.6
  • 3
    • 33244469927 scopus 로고    scopus 로고
    • Age at disability milestones in multiple sclerosis
    • Confavreux C, Vukusic S: Age at disability milestones in multiple sclerosis. Brain 2006, 129: 595-605. 10.1093/brain/awh714
    • (2006) Brain , vol.129 , pp. 595-605
    • Confavreux, C.1    Vukusic, S.2
  • 4
    • 33244466021 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: a unifying concept
    • Confavreux C, Vukusic S: Natural history of multiple sclerosis: a unifying concept. Brain 2006, 129: 606-616. 10.1093/brain/awl007
    • (2006) Brain , vol.129 , pp. 606-616
    • Confavreux, C.1    Vukusic, S.2
  • 5
    • 0034992601 scopus 로고    scopus 로고
    • Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences
    • Bjartmar C, Trapp BD: Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences. Curr Opin Neurol 2001, 14: 271-278. 10.1097/00019052-200106000-00003
    • (2001) Curr Opin Neurol , vol.14 , pp. 271-278
    • Bjartmar, C.1    Trapp, B.D.2
  • 6
    • 0642345898 scopus 로고    scopus 로고
    • Axonal degeneration and progressive neurologic disability in multiple sclerosis
    • Bjartmar C, Trapp BD: Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res 2003, 5: 157-164. 10.1007/BF03033380
    • (2003) Neurotox Res , vol.5 , pp. 157-164
    • Bjartmar, C.1    Trapp, B.D.2
  • 7
    • 34249781999 scopus 로고    scopus 로고
    • Pathogenesis of axonal and neuronal damage in multiple sclerosis
    • Dutta R, Trapp BD: Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology 2007, 68: S22-S31. 10.1212/01.wnl.0000275229.13012.32
    • (2007) Neurology , vol.68 , pp. S22-S31
    • Dutta, R.1    Trapp, B.D.2
  • 8
    • 15044357461 scopus 로고    scopus 로고
    • Inflammation stimulates remyelination in areas of chronic demyelination
    • Foote AK, Blakemore WF: Inflammation stimulates remyelination in areas of chronic demyelination. Brain 2005, 128: 528-539. 10.1093/brain/awh417
    • (2005) Brain , vol.128 , pp. 528-539
    • Foote, A.K.1    Blakemore, W.F.2
  • 10
    • 33748143936 scopus 로고    scopus 로고
    • Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells
    • Setzu A, Lathia JD, Zhao C, Wells K, Rao MS, Ffrench-Constant C, et al.: Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia 2006, 54: 297-303. 10.1002/glia.20371
    • (2006) Glia , vol.54 , pp. 297-303
    • Setzu, A.1    Lathia, J.D.2    Zhao, C.3    Wells, K.4    Rao, M.S.5    Ffrench-Constant, C.6
  • 11
    • 46849092175 scopus 로고    scopus 로고
    • Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Anderson JM, Hampton DW, Patani R, Pryce G, Crowther RA, Reynolds R, et al.: Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain 2008, 131: 1736-1748. 10.1093/brain/awn119
    • (2008) Brain , vol.131 , pp. 1736-1748
    • Anderson, J.M.1    Hampton, D.W.2    Patani, R.3    Pryce, G.4    Crowther, R.A.5    Reynolds, R.6
  • 12
    • 0025362249 scopus 로고
    • Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice
    • Baker D, O'Neill JK, Gschmeissner SE, Wilcox CE, Butter C, Turk JL: Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice. J Neuroimmunol 1990, 28: 261-270. 10.1016/0165-5728(90)90019-J
    • (1990) J Neuroimmunol , vol.28 , pp. 261-270
    • Baker, D.1    O'Neill, J.K.2    Gschmeissner, S.E.3    Wilcox, C.E.4    Butter, C.5    Turk, J.L.6
  • 13
    • 51649118004 scopus 로고    scopus 로고
    • An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss
    • Hampton DW, Anderson J, Pryce G, Irvine KA, Giovannoni G, Fawcett JW, et al.: An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss. J Neuroimmunol 2008, 201-202: 200-211.
    • (2008) J Neuroimmunol , vol.201-202 , pp. 200-211
    • Hampton, D.W.1    Anderson, J.2    Pryce, G.3    Irvine, K.A.4    Giovannoni, G.5    Fawcett, J.W.6
  • 14
    • 0021249555 scopus 로고
    • An immunohistochemical study of myelin proteins during remyelination in the central nervous system
    • Ludwin SK, Sternberger NH: An immunohistochemical study of myelin proteins during remyelination in the central nervous system. Acta Neuropathol 1984,63(3):240-248. 10.1007/BF00685250
    • (1984) Acta Neuropathol , vol.63 , Issue.3 , pp. 240-248
    • Ludwin, S.K.1    Sternberger, N.H.2
  • 16
    • 0037622169 scopus 로고    scopus 로고
    • Quantification of neurodegeneration by measurement of brain-specific proteins
    • Petzold A, Baker D, Pryce G, Keir G, Thompson EJ, Giovannoni G: Quantification of neurodegeneration by measurement of brain-specific proteins. J Neuroimmunol 2003, 138: 45-48. 10.1016/S0165-5728(03)00092-4
    • (2003) J Neuroimmunol , vol.138 , pp. 45-48
    • Petzold, A.1    Baker, D.2    Pryce, G.3    Keir, G.4    Thompson, E.J.5    Giovannoni, G.6
  • 17
    • 22144480216 scopus 로고    scopus 로고
    • Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis
    • Pryce G, O'Neill JK, Croxford JL, Amor S, Hankey DJ, East E, et al.: Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis. J Neuroimmunol 2005, 165: 41-52. 10.1016/j.jneuroim.2005.04.009
    • (2005) J Neuroimmunol , vol.165 , pp. 41-52
    • Pryce, G.1    O'Neill, J.K.2    Croxford, J.L.3    Amor, S.4    Hankey, D.J.5    East, E.6
  • 18
    • 20444474422 scopus 로고    scopus 로고
    • Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice
    • Smith PA, Morris-Downes M, Heijmans N, Pryce G, Arter E, O'Neill JK, et al.: Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice. J Neuroimmunol 2005, 164: 76-84. 10.1016/j.jneuroim.2005.04.006
    • (2005) J Neuroimmunol , vol.164 , pp. 76-84
    • Smith, P.A.1    Morris-Downes, M.2    Heijmans, N.3    Pryce, G.4    Arter, E.5    O'Neill, J.K.6
  • 19
    • 79960258821 scopus 로고    scopus 로고
    • Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis
    • Al-Izki S, Pryce G, Jackson SJ, Giovannoni G, Baker D: Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis. Mult Scler 2011, 17: 939-948. 10.1177/1352458511400476
    • (2011) Mult Scler , vol.17 , pp. 939-948
    • Al-Izki, S.1    Pryce, G.2    Jackson, S.J.3    Giovannoni, G.4    Baker, D.5
  • 20
    • 80054714639 scopus 로고    scopus 로고
    • Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse
    • Al-Izki S, Pryce G, O'Neill JK, Butter C, Giovannoni G, Amor S, Baker D: Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Mult Scler Rel Dis 2012, 1: 29-38.
    • (2012) Mult Scler Rel Dis , vol.1 , pp. 29-38
    • Al-Izki, S.1    Pryce, G.2    O'Neill, J.K.3    Butter, C.4    Giovannoni, G.5    Amor, S.6    Baker, D.7
  • 21
  • 22
    • 33847409329 scopus 로고    scopus 로고
    • Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy
    • Hampton DW, Steeves JD, Fawcett JW, Ramer MS: Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy. Exp Neuro 2007, 204: 366-379. 10.1016/j.expneurol.2006.11.017
    • (2007) Exp Neuro , vol.204 , pp. 366-379
    • Hampton, D.W.1    Steeves, J.D.2    Fawcett, J.W.3    Ramer, M.S.4
  • 23
    • 13244288014 scopus 로고    scopus 로고
    • Deafferentation and neurotrophin-mediated intraspinal sprouting: a central role for the p75 neurotrophin receptor
    • Scott AL, Borisoff JF, Ramer MS: Deafferentation and neurotrophin-mediated intraspinal sprouting: a central role for the p75 neurotrophin receptor. Eur J Neurosci 2005, 21: 81-92. 10.1111/j.1460-9568.2004.03838.x
    • (2005) Eur J Neurosci , vol.21 , pp. 81-92
    • Scott, A.L.1    Borisoff, J.F.2    Ramer, M.S.3
  • 24
    • 77950594305 scopus 로고    scopus 로고
    • Coggeshall RE: Sensory Mechanisms of the Spinal Cord
    • New York: Kluwer Academic/Plenum Publishers;
    • Willis WD, Coggeshall RE: Sensory Mechanisms of the Spinal Cord. New York: Kluwer Academic/Plenum Publishers; 2004.
    • (2004)
    • Willis, W.D.1
  • 25
    • 67649389705 scopus 로고    scopus 로고
    • Quantification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse
    • Jackson SJ, Lee J, Nikodemova M, Fabry Z, Duncan ID: Quantification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. J Neuropathol Exp Neurol 2009, 68: 616-625. 10.1097/NEN.0b013e3181a41d23
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 616-625
    • Jackson, S.J.1    Lee, J.2    Nikodemova, M.3    Fabry, Z.4    Duncan, I.D.5
  • 26
    • 26644472170 scopus 로고    scopus 로고
    • Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG
    • Hazama GI, Yasuhara O, Morita H, Aimi Y, Tooyama I, Kimura H: Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG. J Comp Neurol 2005, 492: 234-249. 10.1002/cne.20710
    • (2005) J Comp Neurol , vol.492 , pp. 234-249
    • Hazama, G.I.1    Yasuhara, O.2    Morita, H.3    Aimi, Y.4    Tooyama, I.5    Kimura, H.6
  • 27
    • 1442348409 scopus 로고    scopus 로고
    • Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis
    • Szalai AJ, Barnum SR: Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis. J Neurosci Res 2004, 75: 597-602. 10.1002/jnr.20023
    • (2004) J Neurosci Res , vol.75 , pp. 597-602
    • Szalai, A.J.1    Barnum, S.R.2
  • 28
    • 78049450207 scopus 로고    scopus 로고
    • Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury
    • Readnower RD, Chavko M, Adeeb S, Conroy MD, Pauly JR, McCarron RM, et al.: Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury. J Neurosci Res 2010, 88: 3530-3539. 10.1002/jnr.22510
    • (2010) J Neurosci Res , vol.88 , pp. 3530-3539
    • Readnower, R.D.1    Chavko, M.2    Adeeb, S.3    Conroy, M.D.4    Pauly, J.R.5    McCarron, R.M.6
  • 29
    • 33645733075 scopus 로고    scopus 로고
    • Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus
    • Ryu JK, McLarnon JG: Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus. Exp Neurol 2006, 198: 552-557. 10.1016/j.expneurol.2005.12.016
    • (2006) Exp Neurol , vol.198 , pp. 552-557
    • Ryu, J.K.1    McLarnon, J.G.2
  • 30
    • 72949097024 scopus 로고    scopus 로고
    • Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord
    • Schirmer L, Albert M, Buss A, Schulz-Schaeffer WJ, Antel JP, Brück W, et al.: Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol 2009,66(5):698-704. 10.1002/ana.21799
    • (2009) Ann Neurol , vol.66 , Issue.5 , pp. 698-704
    • Schirmer, L.1    Albert, M.2    Buss, A.3    Schulz-Schaeffer, W.J.4    Antel, J.P.5    Brück, W.6
  • 31
    • 70350044493 scopus 로고    scopus 로고
    • Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Vogt J, Paul F, Aktas O, Müller-Wielsch K, Dörr J, Dörr S, et al.: Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol 2009,66(3):310-322. 10.1002/ana.21719
    • (2009) Ann Neurol , vol.66 , Issue.3 , pp. 310-322
    • Vogt, J.1    Paul, F.2    Aktas, O.3    Müller-Wielsch, K.4    Dörr, J.5    Dörr, S.6
  • 32
    • 2642557746 scopus 로고    scopus 로고
    • Campath-1H treatment of multiple sclerosis: lessons from the bedside for the bench
    • Coles A, Deans J, Compston A: Campath-1H treatment of multiple sclerosis: lessons from the bedside for the bench. Clin Neurol Neurosurg 2004, 106: 270-274. 10.1016/j.clineuro.2004.02.013
    • (2004) Clin Neurol Neurosurg , vol.106 , pp. 270-274
    • Coles, A.1    Deans, J.2    Compston, A.3
  • 34
    • 73049105525 scopus 로고    scopus 로고
    • Remyelination - An effective means of neuroprotection
    • Bruce CC, Zhao C, Franklin RJ: Remyelination - An effective means of neuroprotection. Horm Behav 2010,57(1):56-62. 10.1016/j.yhbeh.2009.06.004
    • (2010) Horm Behav , vol.57 , Issue.1 , pp. 56-62
    • Bruce, C.C.1    Zhao, C.2    Franklin, R.J.3
  • 36
    • 44949177395 scopus 로고    scopus 로고
    • Remyelination protects axons from demyelination- associated axon degeneration
    • Irvine KA, Blakemore WF: Remyelination protects axons from demyelination- associated axon degeneration. Brain 2008, 131: 1464-1477. 10.1093/brain/awn080
    • (2008) Brain , vol.131 , pp. 1464-1477
    • Irvine, K.A.1    Blakemore, W.F.2
  • 37
    • 84860235395 scopus 로고    scopus 로고
    • Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency
    • Hampton DW, Innes N, Merkler D, Zhao C, Franklin RJ, Chandran S: Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency. Am J Pathol 2012, 180: 1897-1905. 10.1016/j.ajpath.2012.01.018
    • (2012) Am J Pathol , vol.180 , pp. 1897-1905
    • Hampton, D.W.1    Innes, N.2    Merkler, D.3    Zhao, C.4    Franklin, R.J.5    Chandran, S.6
  • 38
    • 50249167673 scopus 로고    scopus 로고
    • Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
    • Shen S, Sandoval J, Swiss VA, Li J, Dupree J, Franklin RJ, Casaccia-Bonnefil P: Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 2008,11(9):1024-1034. 10.1038/nn.2172
    • (2008) Nat Neurosci , vol.11 , Issue.9 , pp. 1024-1034
    • Shen, S.1    Sandoval, J.2    Swiss, V.A.3    Li, J.4    Dupree, J.5    Franklin, R.J.6    Casaccia-Bonnefil, P.7
  • 39
    • 0033215282 scopus 로고    scopus 로고
    • Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin-induced CNS demyelination
    • Shields S, Gilson J, Blakemore W, Franklin R: Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin-induced CNS demyelination. Glia 1999,28(1):77-83. 10.1002/(SICI)1098-1136(199910)28:1<77::AID-GLIA9>3.0.CO;2-F
    • (1999) Glia , vol.28 , Issue.1 , pp. 77-83
    • Shields, S.1    Gilson, J.2    Blakemore, W.3    Franklin, R.4


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