-
1
-
-
54149084585
-
Multiple sclerosis
-
Compston A, Coles A: Multiple sclerosis. Lancet 2008, 372: 1502-1517. 10.1016/S0140-6736(08)61620-7
-
(2008)
Lancet
, vol.372
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
2
-
-
33644974688
-
Secondary progressive multiple sclerosis: current knowledge and future challenges
-
Rovaris M, Confavreux C, Furlan R, Kappos L, Comi G, Filippi M: Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol 2006, 5: 343-354. 10.1016/S1474-4422(06)70410-0
-
(2006)
Lancet Neurol
, vol.5
, pp. 343-354
-
-
Rovaris, M.1
Confavreux, C.2
Furlan, R.3
Kappos, L.4
Comi, G.5
Filippi, M.6
-
3
-
-
33244469927
-
Age at disability milestones in multiple sclerosis
-
Confavreux C, Vukusic S: Age at disability milestones in multiple sclerosis. Brain 2006, 129: 595-605. 10.1093/brain/awh714
-
(2006)
Brain
, vol.129
, pp. 595-605
-
-
Confavreux, C.1
Vukusic, S.2
-
4
-
-
33244466021
-
Natural history of multiple sclerosis: a unifying concept
-
Confavreux C, Vukusic S: Natural history of multiple sclerosis: a unifying concept. Brain 2006, 129: 606-616. 10.1093/brain/awl007
-
(2006)
Brain
, vol.129
, pp. 606-616
-
-
Confavreux, C.1
Vukusic, S.2
-
5
-
-
0034992601
-
Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences
-
Bjartmar C, Trapp BD: Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences. Curr Opin Neurol 2001, 14: 271-278. 10.1097/00019052-200106000-00003
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 271-278
-
-
Bjartmar, C.1
Trapp, B.D.2
-
6
-
-
0642345898
-
Axonal degeneration and progressive neurologic disability in multiple sclerosis
-
Bjartmar C, Trapp BD: Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res 2003, 5: 157-164. 10.1007/BF03033380
-
(2003)
Neurotox Res
, vol.5
, pp. 157-164
-
-
Bjartmar, C.1
Trapp, B.D.2
-
7
-
-
34249781999
-
Pathogenesis of axonal and neuronal damage in multiple sclerosis
-
Dutta R, Trapp BD: Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology 2007, 68: S22-S31. 10.1212/01.wnl.0000275229.13012.32
-
(2007)
Neurology
, vol.68
, pp. S22-S31
-
-
Dutta, R.1
Trapp, B.D.2
-
8
-
-
15044357461
-
Inflammation stimulates remyelination in areas of chronic demyelination
-
Foote AK, Blakemore WF: Inflammation stimulates remyelination in areas of chronic demyelination. Brain 2005, 128: 528-539. 10.1093/brain/awh417
-
(2005)
Brain
, vol.128
, pp. 528-539
-
-
Foote, A.K.1
Blakemore, W.F.2
-
9
-
-
84862908705
-
Rejuvenation of regeneration in the aging central nervous system
-
Ruckh JM, Zhao JW, Shadrach JL, van Wijngaarden P, Rao TN, Wagers AJ, et al.: Rejuvenation of regeneration in the aging central nervous system. Cell Stem Cell 2012, 10: 96-103. 10.1016/j.stem.2011.11.019
-
(2012)
Cell Stem Cell
, vol.10
, pp. 96-103
-
-
Ruckh, J.M.1
Zhao, J.W.2
Shadrach, J.L.3
van Wijngaarden, P.4
Rao, T.N.5
Wagers, A.J.6
-
10
-
-
33748143936
-
Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells
-
Setzu A, Lathia JD, Zhao C, Wells K, Rao MS, Ffrench-Constant C, et al.: Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia 2006, 54: 297-303. 10.1002/glia.20371
-
(2006)
Glia
, vol.54
, pp. 297-303
-
-
Setzu, A.1
Lathia, J.D.2
Zhao, C.3
Wells, K.4
Rao, M.S.5
Ffrench-Constant, C.6
-
11
-
-
46849092175
-
Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Anderson JM, Hampton DW, Patani R, Pryce G, Crowther RA, Reynolds R, et al.: Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain 2008, 131: 1736-1748. 10.1093/brain/awn119
-
(2008)
Brain
, vol.131
, pp. 1736-1748
-
-
Anderson, J.M.1
Hampton, D.W.2
Patani, R.3
Pryce, G.4
Crowther, R.A.5
Reynolds, R.6
-
12
-
-
0025362249
-
Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice
-
Baker D, O'Neill JK, Gschmeissner SE, Wilcox CE, Butter C, Turk JL: Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice. J Neuroimmunol 1990, 28: 261-270. 10.1016/0165-5728(90)90019-J
-
(1990)
J Neuroimmunol
, vol.28
, pp. 261-270
-
-
Baker, D.1
O'Neill, J.K.2
Gschmeissner, S.E.3
Wilcox, C.E.4
Butter, C.5
Turk, J.L.6
-
13
-
-
51649118004
-
An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss
-
Hampton DW, Anderson J, Pryce G, Irvine KA, Giovannoni G, Fawcett JW, et al.: An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss. J Neuroimmunol 2008, 201-202: 200-211.
-
(2008)
J Neuroimmunol
, vol.201-202
, pp. 200-211
-
-
Hampton, D.W.1
Anderson, J.2
Pryce, G.3
Irvine, K.A.4
Giovannoni, G.5
Fawcett, J.W.6
-
14
-
-
0021249555
-
An immunohistochemical study of myelin proteins during remyelination in the central nervous system
-
Ludwin SK, Sternberger NH: An immunohistochemical study of myelin proteins during remyelination in the central nervous system. Acta Neuropathol 1984,63(3):240-248. 10.1007/BF00685250
-
(1984)
Acta Neuropathol
, vol.63
, Issue.3
, pp. 240-248
-
-
Ludwin, S.K.1
Sternberger, N.H.2
-
15
-
-
84857539822
-
Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis
-
Manrique-Hoyos N, Jürgens T, Grønborg M, Kreutzfeldt M, Schedensack M, Kuhlmann T, Schrick C, Brück W, Urlaub H, Simons M, Merkler D: Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Ann Neurol 2012, 71: 227-244. 10.1002/ana.22681
-
(2012)
Ann Neurol
, vol.71
, pp. 227-244
-
-
Manrique-Hoyos, N.1
Jürgens, T.2
Grønborg, M.3
Kreutzfeldt, M.4
Schedensack, M.5
Kuhlmann, T.6
Schrick, C.7
Brück, W.8
Urlaub, H.9
Simons, M.10
Merkler, D.11
-
16
-
-
0037622169
-
Quantification of neurodegeneration by measurement of brain-specific proteins
-
Petzold A, Baker D, Pryce G, Keir G, Thompson EJ, Giovannoni G: Quantification of neurodegeneration by measurement of brain-specific proteins. J Neuroimmunol 2003, 138: 45-48. 10.1016/S0165-5728(03)00092-4
-
(2003)
J Neuroimmunol
, vol.138
, pp. 45-48
-
-
Petzold, A.1
Baker, D.2
Pryce, G.3
Keir, G.4
Thompson, E.J.5
Giovannoni, G.6
-
17
-
-
22144480216
-
Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis
-
Pryce G, O'Neill JK, Croxford JL, Amor S, Hankey DJ, East E, et al.: Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis. J Neuroimmunol 2005, 165: 41-52. 10.1016/j.jneuroim.2005.04.009
-
(2005)
J Neuroimmunol
, vol.165
, pp. 41-52
-
-
Pryce, G.1
O'Neill, J.K.2
Croxford, J.L.3
Amor, S.4
Hankey, D.J.5
East, E.6
-
18
-
-
20444474422
-
Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice
-
Smith PA, Morris-Downes M, Heijmans N, Pryce G, Arter E, O'Neill JK, et al.: Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice. J Neuroimmunol 2005, 164: 76-84. 10.1016/j.jneuroim.2005.04.006
-
(2005)
J Neuroimmunol
, vol.164
, pp. 76-84
-
-
Smith, P.A.1
Morris-Downes, M.2
Heijmans, N.3
Pryce, G.4
Arter, E.5
O'Neill, J.K.6
-
19
-
-
79960258821
-
Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis
-
Al-Izki S, Pryce G, Jackson SJ, Giovannoni G, Baker D: Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis. Mult Scler 2011, 17: 939-948. 10.1177/1352458511400476
-
(2011)
Mult Scler
, vol.17
, pp. 939-948
-
-
Al-Izki, S.1
Pryce, G.2
Jackson, S.J.3
Giovannoni, G.4
Baker, D.5
-
20
-
-
80054714639
-
Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse
-
Al-Izki S, Pryce G, O'Neill JK, Butter C, Giovannoni G, Amor S, Baker D: Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Mult Scler Rel Dis 2012, 1: 29-38.
-
(2012)
Mult Scler Rel Dis
, vol.1
, pp. 29-38
-
-
Al-Izki, S.1
Pryce, G.2
O'Neill, J.K.3
Butter, C.4
Giovannoni, G.5
Amor, S.6
Baker, D.7
-
21
-
-
4143101444
-
Altered CNS response to injury in the MRL/MpJ mouse
-
Hampton DW, Seitz A, Chen P, Heber-Katz E, Fawcett JW: Altered CNS response to injury in the MRL/MpJ mouse. Neuroscience 2004, 127: 821-832. 10.1016/j.neuroscience.2004.05.057
-
(2004)
Neuroscience
, vol.127
, pp. 821-832
-
-
Hampton, D.W.1
Seitz, A.2
Chen, P.3
Heber-Katz, E.4
Fawcett, J.W.5
-
22
-
-
33847409329
-
Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy
-
Hampton DW, Steeves JD, Fawcett JW, Ramer MS: Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy. Exp Neuro 2007, 204: 366-379. 10.1016/j.expneurol.2006.11.017
-
(2007)
Exp Neuro
, vol.204
, pp. 366-379
-
-
Hampton, D.W.1
Steeves, J.D.2
Fawcett, J.W.3
Ramer, M.S.4
-
23
-
-
13244288014
-
Deafferentation and neurotrophin-mediated intraspinal sprouting: a central role for the p75 neurotrophin receptor
-
Scott AL, Borisoff JF, Ramer MS: Deafferentation and neurotrophin-mediated intraspinal sprouting: a central role for the p75 neurotrophin receptor. Eur J Neurosci 2005, 21: 81-92. 10.1111/j.1460-9568.2004.03838.x
-
(2005)
Eur J Neurosci
, vol.21
, pp. 81-92
-
-
Scott, A.L.1
Borisoff, J.F.2
Ramer, M.S.3
-
24
-
-
77950594305
-
Coggeshall RE: Sensory Mechanisms of the Spinal Cord
-
New York: Kluwer Academic/Plenum Publishers;
-
Willis WD, Coggeshall RE: Sensory Mechanisms of the Spinal Cord. New York: Kluwer Academic/Plenum Publishers; 2004.
-
(2004)
-
-
Willis, W.D.1
-
25
-
-
67649389705
-
Quantification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse
-
Jackson SJ, Lee J, Nikodemova M, Fabry Z, Duncan ID: Quantification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. J Neuropathol Exp Neurol 2009, 68: 616-625. 10.1097/NEN.0b013e3181a41d23
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 616-625
-
-
Jackson, S.J.1
Lee, J.2
Nikodemova, M.3
Fabry, Z.4
Duncan, I.D.5
-
26
-
-
26644472170
-
Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG
-
Hazama GI, Yasuhara O, Morita H, Aimi Y, Tooyama I, Kimura H: Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG. J Comp Neurol 2005, 492: 234-249. 10.1002/cne.20710
-
(2005)
J Comp Neurol
, vol.492
, pp. 234-249
-
-
Hazama, G.I.1
Yasuhara, O.2
Morita, H.3
Aimi, Y.4
Tooyama, I.5
Kimura, H.6
-
27
-
-
1442348409
-
Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis
-
Szalai AJ, Barnum SR: Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis. J Neurosci Res 2004, 75: 597-602. 10.1002/jnr.20023
-
(2004)
J Neurosci Res
, vol.75
, pp. 597-602
-
-
Szalai, A.J.1
Barnum, S.R.2
-
28
-
-
78049450207
-
Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury
-
Readnower RD, Chavko M, Adeeb S, Conroy MD, Pauly JR, McCarron RM, et al.: Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury. J Neurosci Res 2010, 88: 3530-3539. 10.1002/jnr.22510
-
(2010)
J Neurosci Res
, vol.88
, pp. 3530-3539
-
-
Readnower, R.D.1
Chavko, M.2
Adeeb, S.3
Conroy, M.D.4
Pauly, J.R.5
McCarron, R.M.6
-
29
-
-
33645733075
-
Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus
-
Ryu JK, McLarnon JG: Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus. Exp Neurol 2006, 198: 552-557. 10.1016/j.expneurol.2005.12.016
-
(2006)
Exp Neurol
, vol.198
, pp. 552-557
-
-
Ryu, J.K.1
McLarnon, J.G.2
-
30
-
-
72949097024
-
Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord
-
Schirmer L, Albert M, Buss A, Schulz-Schaeffer WJ, Antel JP, Brück W, et al.: Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol 2009,66(5):698-704. 10.1002/ana.21799
-
(2009)
Ann Neurol
, vol.66
, Issue.5
, pp. 698-704
-
-
Schirmer, L.1
Albert, M.2
Buss, A.3
Schulz-Schaeffer, W.J.4
Antel, J.P.5
Brück, W.6
-
31
-
-
70350044493
-
Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
-
Vogt J, Paul F, Aktas O, Müller-Wielsch K, Dörr J, Dörr S, et al.: Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol 2009,66(3):310-322. 10.1002/ana.21719
-
(2009)
Ann Neurol
, vol.66
, Issue.3
, pp. 310-322
-
-
Vogt, J.1
Paul, F.2
Aktas, O.3
Müller-Wielsch, K.4
Dörr, J.5
Dörr, S.6
-
32
-
-
2642557746
-
Campath-1H treatment of multiple sclerosis: lessons from the bedside for the bench
-
Coles A, Deans J, Compston A: Campath-1H treatment of multiple sclerosis: lessons from the bedside for the bench. Clin Neurol Neurosurg 2004, 106: 270-274. 10.1016/j.clineuro.2004.02.013
-
(2004)
Clin Neurol Neurosurg
, vol.106
, pp. 270-274
-
-
Coles, A.1
Deans, J.2
Compston, A.3
-
33
-
-
54949143968
-
Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
-
Coles AJ, Compston DA, Selmaj KW, Lake SL, Moran S, Margolin DH, et al.: Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N Engl J Med 2008, 359: 1786-1801.
-
(2008)
N Engl J Med
, vol.359
, pp. 1786-1801
-
-
Coles, A.J.1
Compston, D.A.2
Selmaj, K.W.3
Lake, S.L.4
Moran, S.5
Margolin, D.H.6
-
34
-
-
73049105525
-
Remyelination - An effective means of neuroprotection
-
Bruce CC, Zhao C, Franklin RJ: Remyelination - An effective means of neuroprotection. Horm Behav 2010,57(1):56-62. 10.1016/j.yhbeh.2009.06.004
-
(2010)
Horm Behav
, vol.57
, Issue.1
, pp. 56-62
-
-
Bruce, C.C.1
Zhao, C.2
Franklin, R.J.3
-
35
-
-
84868551387
-
Neuroprotection and repair in multiple sclerosis
-
Franklin RJ, Ffrench-Constant C, Edgar JM, Smith KJ: Neuroprotection and repair in multiple sclerosis. Nat Rev Neurol 2012,8(11):624-634. 10.1038/nrneurol.2012.200
-
(2012)
Nat Rev Neurol
, vol.8
, Issue.11
, pp. 624-634
-
-
Franklin, R.J.1
Ffrench-Constant, C.2
Edgar, J.M.3
Smith, K.J.4
-
36
-
-
44949177395
-
Remyelination protects axons from demyelination- associated axon degeneration
-
Irvine KA, Blakemore WF: Remyelination protects axons from demyelination- associated axon degeneration. Brain 2008, 131: 1464-1477. 10.1093/brain/awn080
-
(2008)
Brain
, vol.131
, pp. 1464-1477
-
-
Irvine, K.A.1
Blakemore, W.F.2
-
37
-
-
84860235395
-
Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency
-
Hampton DW, Innes N, Merkler D, Zhao C, Franklin RJ, Chandran S: Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency. Am J Pathol 2012, 180: 1897-1905. 10.1016/j.ajpath.2012.01.018
-
(2012)
Am J Pathol
, vol.180
, pp. 1897-1905
-
-
Hampton, D.W.1
Innes, N.2
Merkler, D.3
Zhao, C.4
Franklin, R.J.5
Chandran, S.6
-
38
-
-
50249167673
-
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
-
Shen S, Sandoval J, Swiss VA, Li J, Dupree J, Franklin RJ, Casaccia-Bonnefil P: Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 2008,11(9):1024-1034. 10.1038/nn.2172
-
(2008)
Nat Neurosci
, vol.11
, Issue.9
, pp. 1024-1034
-
-
Shen, S.1
Sandoval, J.2
Swiss, V.A.3
Li, J.4
Dupree, J.5
Franklin, R.J.6
Casaccia-Bonnefil, P.7
-
39
-
-
0033215282
-
Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin-induced CNS demyelination
-
Shields S, Gilson J, Blakemore W, Franklin R: Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin-induced CNS demyelination. Glia 1999,28(1):77-83. 10.1002/(SICI)1098-1136(199910)28:1<77::AID-GLIA9>3.0.CO;2-F
-
(1999)
Glia
, vol.28
, Issue.1
, pp. 77-83
-
-
Shields, S.1
Gilson, J.2
Blakemore, W.3
Franklin, R.4
|