-
1
-
-
84969672767
-
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
-
1 Zanos, P., Moaddel, R., Morris, P.J., Georgiou, P., Fischell, J., Elmer, G.I., et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature 533 (2016), 481–486.
-
(2016)
Nature
, vol.533
, pp. 481-486
-
-
Zanos, P.1
Moaddel, R.2
Morris, P.J.3
Georgiou, P.4
Fischell, J.5
Elmer, G.I.6
-
2
-
-
84864286398
-
Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression
-
2 Zarate, C.A. Jr, Brutsche, N., Laje, G., Luckenbaugh, D.A., Venkata, S.L., Ramamoorthy, A., et al. Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biol Psychiatry 72 (2012), 331–338.
-
(2012)
Biol Psychiatry
, vol.72
, pp. 331-338
-
-
Zarate, C.A.1
Brutsche, N.2
Laje, G.3
Luckenbaugh, D.A.4
Venkata, S.L.5
Ramamoorthy, A.6
-
3
-
-
85006115771
-
Antidepressant actions of ketamine versus hydroxynorketamine
-
3 Collingridge, G., Lee, Y., Bortolotto, Z., Kang, H., Lodge, D., Antidepressant actions of ketamine versus hydroxynorketamine. Biol Psychiatry 81 (2017), e65–e67.
-
(2017)
Biol Psychiatry
, vol.81
, pp. e65-e67
-
-
Collingridge, G.1
Lee, Y.2
Bortolotto, Z.3
Kang, H.4
Lodge, D.5
-
4
-
-
84950154619
-
Intravenous esketamine in adult treatment-resistant depression: A double-blind, double-randomization, placebo-controlled study
-
4 Singh, J.B., Fedgchin, M., Daly, E., Xi, L., Melman, C., De Bruecker, G., et al. Intravenous esketamine in adult treatment-resistant depression: A double-blind, double-randomization, placebo-controlled study. Biol Psychiatry 80 (2016), 424–431.
-
(2016)
Biol Psychiatry
, vol.80
, pp. 424-431
-
-
Singh, J.B.1
Fedgchin, M.2
Daly, E.3
Xi, L.4
Melman, C.5
De Bruecker, G.6
-
5
-
-
33746896935
-
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression
-
5 Zarate, C.A. Jr, Singh, J.B., Carlson, P.J., Brutsche, N.E., Ameli, R., Luckenbaugh, D.A., et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 63 (2006), 856–864.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 856-864
-
-
Zarate, C.A.1
Singh, J.B.2
Carlson, P.J.3
Brutsche, N.E.4
Ameli, R.5
Luckenbaugh, D.A.6
-
6
-
-
0033969685
-
Antidepressant effects of ketamine in depressed patients
-
6 Berman, R.M., Cappiello, A., Anand, A., Oren, D.A., Heninger, G.R., Charney, D.S., et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 47 (2000), 351–354.
-
(2000)
Biol Psychiatry
, vol.47
, pp. 351-354
-
-
Berman, R.M.1
Cappiello, A.2
Anand, A.3
Oren, D.A.4
Heninger, G.R.5
Charney, D.S.6
-
7
-
-
77955891255
-
A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression
-
7 Diazgranados, N., Ibrahim, L., Brutsche, N.E., Newberg, A., Kronstein, P., Khalife, S., et al. A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression. Arch Gen Psychiatry 67 (2010), 793–802.
-
(2010)
Arch Gen Psychiatry
, vol.67
, pp. 793-802
-
-
Diazgranados, N.1
Ibrahim, L.2
Brutsche, N.E.3
Newberg, A.4
Kronstein, P.5
Khalife, S.6
-
8
-
-
84885214350
-
Antidepressant efficacy of ketamine in treatment-resistant major depression: A two-site randomized controlled trial
-
8 Murrough, J.W., Iosifescu, D.V., Chang, L.C., Al Jurdi, R.K., Green, C.E., Perez, A.M., et al. Antidepressant efficacy of ketamine in treatment-resistant major depression: A two-site randomized controlled trial. Am J Psychiatry 170 (2013), 1134–1142.
-
(2013)
Am J Psychiatry
, vol.170
, pp. 1134-1142
-
-
Murrough, J.W.1
Iosifescu, D.V.2
Chang, L.C.3
Al Jurdi, R.K.4
Green, C.E.5
Perez, A.M.6
-
9
-
-
84991272304
-
A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression
-
9 Singh, J.B., Fedgchin, M., Daly, E.J., De Boer, P., Cooper, K., Lim, P., et al. A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression. Am J Psychiatry 173 (2016), 816–826.
-
(2016)
Am J Psychiatry
, vol.173
, pp. 816-826
-
-
Singh, J.B.1
Fedgchin, M.2
Daly, E.J.3
De Boer, P.4
Cooper, K.5
Lim, P.6
-
10
-
-
84880767967
-
Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression
-
10 Murrough, J.W., Perez, A.M., Pillemer, S., Stern, J., Parides, M.K., aan het Rot, M., et al. Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biol Psychiatry 74 (2013), 250–256.
-
(2013)
Biol Psychiatry
, vol.74
, pp. 250-256
-
-
Murrough, J.W.1
Perez, A.M.2
Pillemer, S.3
Stern, J.4
Parides, M.K.5
aan het Rot, M.6
-
11
-
-
84861099072
-
Replication of ketamine's antidepressant efficacy in bipolar depression: A randomized controlled add-on trial
-
11 Zarate, C.A. Jr, Brutsche, N.E., Ibrahim, L., Franco-Chaves, J., Diazgranados, N., Cravchik, A., et al. Replication of ketamine's antidepressant efficacy in bipolar depression: A randomized controlled add-on trial. Biol Psychiatry 71 (2012), 939–946.
-
(2012)
Biol Psychiatry
, vol.71
, pp. 939-946
-
-
Zarate, C.A.1
Brutsche, N.E.2
Ibrahim, L.3
Franco-Chaves, J.4
Diazgranados, N.5
Cravchik, A.6
-
12
-
-
84940855007
-
R-ketamine: A rapid-onset and sustained antidepressant without psychotomimetic side effects
-
12 Yang, C., Shirayama, Y., Zhang, J.C., Ren, Q., Yao, W., Ma, M., et al. R-ketamine: A rapid-onset and sustained antidepressant without psychotomimetic side effects. Transl Psychiatry, 5, 2015, e632.
-
(2015)
Transl Psychiatry
, vol.5
, pp. e632
-
-
Yang, C.1
Shirayama, Y.2
Zhang, J.C.3
Ren, Q.4
Yao, W.5
Ma, M.6
-
13
-
-
84889953872
-
R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
-
13 Zhang, J.C., Li, S.X., Hashimoto, K., R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine. Pharmacol Biochem Behav 116 (2014), 137–141.
-
(2014)
Pharmacol Biochem Behav
, vol.116
, pp. 137-141
-
-
Zhang, J.C.1
Li, S.X.2
Hashimoto, K.3
-
14
-
-
84908572031
-
Lanicemine: A low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects
-
14 Sanacora, G., Smith, M.A., Pathak, S., Su, H.L., Boeijinga, P.H., McCarthy, D.J., et al. Lanicemine: A low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects. Mol Psychiatry 19 (2014), 978–985.
-
(2014)
Mol Psychiatry
, vol.19
, pp. 978-985
-
-
Sanacora, G.1
Smith, M.A.2
Pathak, S.3
Su, H.L.4
Boeijinga, P.H.5
McCarthy, D.J.6
-
15
-
-
30044450251
-
A double-blind, placebo-controlled study of memantine in the treatment of major depression
-
15 Zarate, C.A. Jr, Singh, J.B., Quiroz, J.A., De Jesus, G., Denicoff, K.K., Luckenbaugh, D.A., et al. A double-blind, placebo-controlled study of memantine in the treatment of major depression. Am J Psychiatry 163 (2006), 153–155.
-
(2006)
Am J Psychiatry
, vol.163
, pp. 153-155
-
-
Zarate, C.A.1
Singh, J.B.2
Quiroz, J.A.3
De Jesus, G.4
Denicoff, K.K.5
Luckenbaugh, D.A.6
-
16
-
-
59049098262
-
An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder
-
16 Preskorn, S.H., Baker, B., Kolluri, S., Menniti, F.S., Krams, M., Landen, J.W., An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. J Clin Psychopharmacol 28 (2008), 631–637.
-
(2008)
J Clin Psychopharmacol
, vol.28
, pp. 631-637
-
-
Preskorn, S.H.1
Baker, B.2
Kolluri, S.3
Menniti, F.S.4
Krams, M.5
Landen, J.W.6
-
17
-
-
84978100390
-
What are we learning from early-phase clinical trials with glutamate targeting medications for the treatment of major depressive disorder
-
17 Sanacora, G., What are we learning from early-phase clinical trials with glutamate targeting medications for the treatment of major depressive disorder. JAMA Psychiatry 73 (2016), 651–652.
-
(2016)
JAMA Psychiatry
, vol.73
, pp. 651-652
-
-
Sanacora, G.1
-
18
-
-
84942851296
-
Ketamine and other NMDA antagonists: Early clinical trials and possible mechanisms in depression
-
18 Newport, D.J., Carpenter, L.L., McDonald, W.M., Potash, J.B., Tohen, M., Nemeroff, C.B., et al. Ketamine and other NMDA antagonists: Early clinical trials and possible mechanisms in depression. Am J Psychiatry 172 (2015), 950–966.
-
(2015)
Am J Psychiatry
, vol.172
, pp. 950-966
-
-
Newport, D.J.1
Carpenter, L.L.2
McDonald, W.M.3
Potash, J.B.4
Tohen, M.5
Nemeroff, C.B.6
-
19
-
-
84900296719
-
Using deuterium in drug discovery: Leaving the label in the drug
-
19 Gant, T.G., Using deuterium in drug discovery: Leaving the label in the drug. J Med Chem 57 (2014), 3595–3611.
-
(2014)
J Med Chem
, vol.57
, pp. 3595-3611
-
-
Gant, T.G.1
-
20
-
-
79960057257
-
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
-
20 Autry, A.E., Adachi, M., Nosyreva, E., Na, E.S., Los, M.F., Cheng, P.F., et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 475 (2011), 91–95.
-
(2011)
Nature
, vol.475
, pp. 91-95
-
-
Autry, A.E.1
Adachi, M.2
Nosyreva, E.3
Na, E.S.4
Los, M.F.5
Cheng, P.F.6
-
21
-
-
77955909841
-
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
-
21 Li, N., Lee, B., Liu, R.J., Banasr, M., Dwyer, J.M., Iwata, M., et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 329 (2010), 959–964.
-
(2010)
Science
, vol.329
, pp. 959-964
-
-
Li, N.1
Lee, B.2
Liu, R.J.3
Banasr, M.4
Dwyer, J.M.5
Iwata, M.6
-
22
-
-
38349186799
-
Cellular mechanisms underlying the antidepressant effects of ketamine: Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors
-
22 Maeng, S., Zarate, C.A. Jr, Du, J., Schloesser, R.J., McCammon, J., Chen, G., et al. Cellular mechanisms underlying the antidepressant effects of ketamine: Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biol Psychiatry 63 (2008), 349–352.
-
(2008)
Biol Psychiatry
, vol.63
, pp. 349-352
-
-
Maeng, S.1
Zarate, C.A.2
Du, J.3
Schloesser, R.J.4
McCammon, J.5
Chen, G.6
-
23
-
-
84928415582
-
An excitatory synapse hypothesis of depression
-
23 Thompson, S.M., Kallarackal, A.J., Kvarta, M.D., Van Dyke, A.M., LeGates, T.A., Cai, X., An excitatory synapse hypothesis of depression. Trends Neurosci 38 (2015), 279–294.
-
(2015)
Trends Neurosci
, vol.38
, pp. 279-294
-
-
Thompson, S.M.1
Kallarackal, A.J.2
Kvarta, M.D.3
Van Dyke, A.M.4
LeGates, T.A.5
Cai, X.6
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