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Volumn 2, Issue 1, 2014, Pages

Decreased neuroinflammation and increased brain energy homeostasis following environmental enrichment after mild traumatic brain injury is associated with improvement in cognitive function

Author keywords

AMPK; IL ; IL10; Non matching to sample task; TNF

Indexed keywords


EID: 85005790387     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-1-57     Document Type: Article
Times cited : (56)

References (51)
  • 1
    • 84983304436 scopus 로고    scopus 로고
    • Traumatic brain injury in the United States: emergency department visits, hospitalizations and deaths 2002-2006
    • Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control
    • Faul MD, Xu L, Wald MM, Coronado VG: Traumatic brain injury in the United States: emergency department visits, hospitalizations and deaths 2002-2006. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control; 2010.
    • (2010)
    • Faul, M.D.1    Xu, L.2    Wald, M.M.3    Coronado, V.G.4
  • 2
    • 33947669404 scopus 로고    scopus 로고
    • Mechanisms of working memory dysfuction after mild and moderate TBI: evidence from functional MRI and neurogenetics
    • McAllister TW, Flashman LA, McDonald BC, Saykin AJ: Mechanisms of working memory dysfuction after mild and moderate TBI: evidence from functional MRI and neurogenetics. J Neurotrauma 2006, 23: 1450-1467. 10.1089/neu.2006.23.1450
    • (2006) J Neurotrauma , vol.23 , pp. 1450-1467
    • McAllister, T.W.1    Flashman, L.A.2    McDonald, B.C.3    Saykin, A.J.4
  • 4
    • 0033648348 scopus 로고    scopus 로고
    • Pathophysiology of neural injury: therapeutic opportunities and challenges
    • Povlishock JT: Pathophysiology of neural injury: therapeutic opportunities and challenges. Clin Neurosurg 2000, 46: 113-126.
    • (2000) Clin Neurosurg , vol.46 , pp. 113-126
    • Povlishock, J.T.1
  • 5
    • 46649098179 scopus 로고    scopus 로고
    • Oxidative stress and modifications of synaptic proteins in hippocampus after traumatic brain injury
    • Ansari MA, Roberts KN, Scheff SW: Oxidative stress and modifications of synaptic proteins in hippocampus after traumatic brain injury. Free Radic Biol Med 2008, 45: 443-452. 10.1016/j.freeradbiomed.2008.04.038
    • (2008) Free Radic Biol Med , vol.45 , pp. 443-452
    • Ansari, M.A.1    Roberts, K.N.2    Scheff, S.W.3
  • 6
    • 84857646218 scopus 로고    scopus 로고
    • Widespread tau and amyloid-beta pathology many years after a single TBI in humans
    • Johnson VE, Stewart W, Smith DH: Widespread tau and amyloid-beta pathology many years after a single TBI in humans. Brain Pathol 2012, 22: 142-149. 10.1111/j.1750-3639.2011.00513.x
    • (2012) Brain Pathol , vol.22 , pp. 142-149
    • Johnson, V.E.1    Stewart, W.2    Smith, D.H.3
  • 7
    • 84873397447 scopus 로고    scopus 로고
    • Inflammation and white matter degeneration persist for years after a single traumatic brain injury
    • Johnson VE, Stewart JE, Begbie FD, Trojanowski JQ, Smith DH, Stewart W: Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain 2013, 136: 28-42.
    • (2013) Brain , vol.136 , pp. 28-42
    • Johnson, V.E.1    Stewart, J.E.2    Begbie, F.D.3    Trojanowski, J.Q.4    Smith, D.H.5    Stewart, W.6
  • 9
    • 50149121229 scopus 로고    scopus 로고
    • Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury
    • Israelsson C, Bengtsson H, Kylberg A, Kullander K, Lewen A, Hillered L, Ebendal T: Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury. J Neurotrauma 2008, 25: 959-974. 10.1089/neu.2008.0562
    • (2008) J Neurotrauma , vol.25 , pp. 959-974
    • Israelsson, C.1    Bengtsson, H.2    Kylberg, A.3    Kullander, K.4    Lewen, A.5    Hillered, L.6    Ebendal, T.7
  • 10
    • 77957086962 scopus 로고    scopus 로고
    • Role of microglia in neurotrauma
    • Loane DJ, Byrnes KR: Role of microglia in neurotrauma. Neurotherapeutics 2010, 7: 366-377. 10.1016/j.nurt.2010.07.002
    • (2010) Neurotherapeutics , vol.7 , pp. 366-377
    • Loane, D.J.1    Byrnes, K.R.2
  • 11
    • 73049110767 scopus 로고    scopus 로고
    • The multifaceted profile of activated microglia
    • Lynch MA: The multifaceted profile of activated microglia. Mol Neurobiol 2009, 40: 139-156. 10.1007/s12035-009-8077-9
    • (2009) Mol Neurobiol , vol.40 , pp. 139-156
    • Lynch, M.A.1
  • 12
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • Block ML, Zecca L, Hong JS: Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev 2007, 8: 57-69. 10.1038/nrn2038
    • (2007) Nat Rev , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 13
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
    • Block ML, Hong JS: Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog Neurobiol 2005, 76: 77-98. 10.1016/j.pneurobio.2005.06.004
    • (2005) Prog Neurobiol , vol.76 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 14
    • 84880275638 scopus 로고    scopus 로고
    • Neuroinflammation: beneficial and detrimental effects after traumatic brain injury
    • Finnie JW: Neuroinflammation: beneficial and detrimental effects after traumatic brain injury. Inflammopharmacology 2013, 21: 309-320. 10.1007/s10787-012-0164-2
    • (2013) Inflammopharmacology , vol.21 , pp. 309-320
    • Finnie, J.W.1
  • 15
    • 84867213778 scopus 로고    scopus 로고
    • Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention
    • Kumar A, Loane DJ: Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain Behav Immun 2012, 26: 1191-1201. 10.1016/j.bbi.2012.06.008
    • (2012) Brain Behav Immun , vol.26 , pp. 1191-1201
    • Kumar, A.1    Loane, D.J.2
  • 16
    • 33747613561 scopus 로고    scopus 로고
    • Enriched environment, experience-dependent plasticity and disorders of the nervous system
    • Nithianantharajah J, Hannan AJ: Enriched environment, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci 2006, 7: 697-709. 10.1038/nrn1970
    • (2006) Nat Rev Neurosci , vol.7 , pp. 697-709
    • Nithianantharajah, J.1    Hannan, A.J.2
  • 17
    • 2342461096 scopus 로고    scopus 로고
    • Recovery from brain injury in animals: relative efficacy of environmental enrichment, physical exercise or formal training (1990-2002)
    • Will B, Galani R, Kelche C, Rosenzweig MR: Recovery from brain injury in animals: relative efficacy of environmental enrichment, physical exercise or formal training (1990-2002). Prog Brain Res 2004, 72: 167-182.
    • (2004) Prog Brain Res , vol.72 , pp. 167-182
    • Will, B.1    Galani, R.2    Kelche, C.3    Rosenzweig, M.R.4
  • 18
    • 32044451083 scopus 로고    scopus 로고
    • Amelioration of cognitive impairment and changes in microtubule-associated protein 2 after transient global cerebral ischemia are influenced by complex environment experience
    • Briones TL, Woods J, Wadowska M, Rogozinska M: Amelioration of cognitive impairment and changes in microtubule-associated protein 2 after transient global cerebral ischemia are influenced by complex environment experience. Behav Brain Res 2006,168(2):261-271. 10.1016/j.bbr.2005.11.015
    • (2006) Behav Brain Res , vol.168 , Issue.2 , pp. 261-271
    • Briones, T.L.1    Woods, J.2    Wadowska, M.3    Rogozinska, M.4
  • 19
    • 33646559857 scopus 로고    scopus 로고
    • Astrocytic changes in the hippocampus and functional recovery after cerebral ischemia are facilitated by rehabilitation training
    • Briones TL, Woods J, Wadowska M, Rogozinska M, Nguyen M: Astrocytic changes in the hippocampus and functional recovery after cerebral ischemia are facilitated by rehabilitation training. Behav Brain Res 2006,171(1):17-25. 10.1016/j.bbr.2006.03.011
    • (2006) Behav Brain Res , vol.171 , Issue.1 , pp. 17-25
    • Briones, T.L.1    Woods, J.2    Wadowska, M.3    Rogozinska, M.4    Nguyen, M.5
  • 20
    • 12944249626 scopus 로고    scopus 로고
    • Dentate gyrus neurogenesis after cerebral ischemia and behavioral training
    • Briones TL, Suh E, Hattar H, Wadowska M: Dentate gyrus neurogenesis after cerebral ischemia and behavioral training. Biol Res Nurs 2005, 6: 167-179. 10.1177/1099800404271328
    • (2005) Biol Res Nurs , vol.6 , pp. 167-179
    • Briones, T.L.1    Suh, E.2    Hattar, H.3    Wadowska, M.4
  • 21
    • 0034172888 scopus 로고    scopus 로고
    • Effects of environment on enhancing functional plasticity following cerebral ischemia
    • Briones TL, Therrien B, Metzger B: Effects of environment on enhancing functional plasticity following cerebral ischemia. Biol Res Nurs 2000, 1: 299-309. 10.1177/109980040000100406
    • (2000) Biol Res Nurs , vol.1 , pp. 299-309
    • Briones, T.L.1    Therrien, B.2    Metzger, B.3
  • 22
    • 84877070827 scopus 로고    scopus 로고
    • Environmental enrichment protects against functional deficits caused by traumatic brain injury
    • Johnson EM, Traver KL, Hoffman SW, Harrison CR, Herman JP: Environmental enrichment protects against functional deficits caused by traumatic brain injury. Front Behav Neurosci 2013., 7: doi:10.3389/fnbeh.2013.00044
    • (2013) Front Behav Neurosci , vol.7
    • Johnson, E.M.1    Traver, K.L.2    Hoffman, S.W.3    Harrison, C.R.4    Herman, J.P.5
  • 23
    • 78649350758 scopus 로고    scopus 로고
    • Evaluation of a combined therapeutic regimen of 8-OH-DPAT and envrionmental enrichment after experimental traumatic brain injury
    • Kline AE, McAloon RL, Henderson KA, Bansal UK, Ganti BM, Ahmed RH, Gibbs RB, Sozda CN: Evaluation of a combined therapeutic regimen of 8-OH-DPAT and envrionmental enrichment after experimental traumatic brain injury. J Neurotrauma 2010, 27: 2021-2032. 10.1089/neu.2010.1535
    • (2010) J Neurotrauma , vol.27 , pp. 2021-2032
    • Kline, A.E.1    McAloon, R.L.2    Henderson, K.A.3    Bansal, U.K.4    Ganti, B.M.5    Ahmed, R.H.6    Gibbs, R.B.7    Sozda, C.N.8
  • 24
    • 79959292466 scopus 로고    scopus 로고
    • Temporal effects of environmental enrichment-mediated functional improvement after experimental traumatic brain injury in rats
    • Matter AM, Folweiler KA, Curatolo LM, Kline AE: Temporal effects of environmental enrichment-mediated functional improvement after experimental traumatic brain injury in rats. Neurorehabil Neural Repair 2011, 25: 558-564. 10.1177/1545968310397206
    • (2011) Neurorehabil Neural Repair , vol.25 , pp. 558-564
    • Matter, A.M.1    Folweiler, K.A.2    Curatolo, L.M.3    Kline, A.E.4
  • 25
    • 20444481708 scopus 로고    scopus 로고
    • Multimodal early onset stimulation combined with enriched environment is associated with reduced CNS lesion volume and enhanced reversal of neuromotor dysfunction after traumatic brain injury
    • Maegele M, Lippert-Gruener M, Ester-Bode T, Garbe J, Bouillon B, Neugebauer E, Kulg N, Lefering R, Neiss WF, Angelov DN: Multimodal early onset stimulation combined with enriched environment is associated with reduced CNS lesion volume and enhanced reversal of neuromotor dysfunction after traumatic brain injury. Eur J Neurol 2005, 21: 2406-2418.
    • (2005) Eur J Neurol , vol.21 , pp. 2406-2418
    • Maegele, M.1    Lippert-Gruener, M.2    Ester-Bode, T.3    Garbe, J.4    Bouillon, B.5    Neugebauer, E.6    Kulg, N.7    Lefering, R.8    Neiss, W.F.9    Angelov, D.N.10
  • 27
    • 84865272331 scopus 로고    scopus 로고
    • Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion
    • Yao ZH, Zhang JJ, Xie XF: Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion. Curr Neurovasc Res 2012, 9: 176-184. 10.2174/156720212801618974
    • (2012) Curr Neurovasc Res , vol.9 , pp. 176-184
    • Yao, Z.H.1    Zhang, J.J.2    Xie, X.F.3
  • 28
    • 84863862485 scopus 로고    scopus 로고
    • Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection
    • Jurgens HA, Johnson RW: Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection. Brain Behav Immun 2012, 26: 1006-1016. 10.1016/j.bbi.2012.05.015
    • (2012) Brain Behav Immun , vol.26 , pp. 1006-1016
    • Jurgens, H.A.1    Johnson, R.W.2
  • 29
    • 0346725081 scopus 로고    scopus 로고
    • Behaviorally-induced ultrastructural plasticity in the hippocampal region after cerebral ischemia
    • Briones TL, Suh E, Jozsa L, Hattar H, Chai J, Wadowska M: Behaviorally-induced ultrastructural plasticity in the hippocampal region after cerebral ischemia. Brain Res 2004, 997: 137-146. 10.1016/j.brainres.2003.10.030
    • (2004) Brain Res , vol.997 , pp. 137-146
    • Briones, T.L.1    Suh, E.2    Jozsa, L.3    Hattar, H.4    Chai, J.5    Wadowska, M.6
  • 30
    • 64849088876 scopus 로고    scopus 로고
    • Environmental experience modulates ischemia-induced amyloidogenesis and enhances functional recovery
    • Briones TL, Rogozinska M, Woods J: Environmental experience modulates ischemia-induced amyloidogenesis and enhances functional recovery. J Neurotrauma 2009, 24: 613-625.
    • (2009) J Neurotrauma , vol.24 , pp. 613-625
    • Briones, T.L.1    Rogozinska, M.2    Woods, J.3
  • 31
    • 0036535031 scopus 로고    scopus 로고
    • Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells
    • Fryer LGD, Foufelle F, Barnes K, Baldwin SA, Woods A, Carling D: Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells. Biochem J 2002, 363: 167-174. 10.1042/0264-6021:3630167
    • (2002) Biochem J , vol.363 , pp. 167-174
    • Fryer, L.G.D.1    Foufelle, F.2    Barnes, K.3    Baldwin, S.A.4    Woods, A.5    Carling, D.6
  • 32
    • 36849019542 scopus 로고    scopus 로고
    • Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro
    • Kleman AM, Yuan JY, Aja S, Ronnett GV, Landree LE: Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro. J Neurosci Methods 2008, 167: 292-301. 10.1016/j.jneumeth.2007.08.028
    • (2008) J Neurosci Methods , vol.167 , pp. 292-301
    • Kleman, A.M.1    Yuan, J.Y.2    Aja, S.3    Ronnett, G.V.4    Landree, L.E.5
  • 33
    • 0037306612 scopus 로고    scopus 로고
    • Resticted neuronal expression of ubiquitous mitochondrial creatine kinase: changing patterns in development and with increased activity
    • Boero J, Qin W, Cheng JP, Woolsey TA, Strauss AW, Khuchua Z: Resticted neuronal expression of ubiquitous mitochondrial creatine kinase: changing patterns in development and with increased activity. Mol Cell Biochem 2003, 244: 69-76. 10.1023/A:1022409101641
    • (2003) Mol Cell Biochem , vol.244 , pp. 69-76
    • Boero, J.1    Qin, W.2    Cheng, J.P.3    Woolsey, T.A.4    Strauss, A.W.5    Khuchua, Z.6
  • 35
    • 0035068201 scopus 로고    scopus 로고
    • Therapeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injuty in rats
    • Passineau MJ, Green EJ, Dietrich WD: Therapeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injuty in rats. Exp Neurol 2001, 168: 373-384. 10.1006/exnr.2000.7623
    • (2001) Exp Neurol , vol.168 , pp. 373-384
    • Passineau, M.J.1    Green, E.J.2    Dietrich, W.D.3
  • 37
    • 84870560220 scopus 로고    scopus 로고
    • A relatively brief exposure to environmental enrichment after eperimental traumatic brain injury confers long-term cognitive benefits
    • Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE: A relatively brief exposure to environmental enrichment after eperimental traumatic brain injury confers long-term cognitive benefits. J Neurotrauma 2012, 29: 2684-2688. 10.1089/neu.2012.2560
    • (2012) J Neurotrauma , vol.29 , pp. 2684-2688
    • Cheng, J.P.1    Shaw, K.E.2    Monaco, C.M.3    Hoffman, A.N.4    Sozda, C.N.5    Olsen, A.S.6    Kline, A.E.7
  • 38
    • 1642523428 scopus 로고    scopus 로고
    • Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after TBI
    • Wilson S, Raghupathi R, Saatman KE, Mackinnon MA, McIntosh TK, Graham DI: Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after TBI. J Neurotrauma 2004, 21: 239-250. 10.1089/089771504322972031
    • (2004) J Neurotrauma , vol.21 , pp. 239-250
    • Wilson, S.1    Raghupathi, R.2    Saatman, K.E.3    Mackinnon, M.A.4    McIntosh, T.K.5    Graham, D.I.6
  • 39
    • 0032551652 scopus 로고    scopus 로고
    • Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats
    • Pierce JE, Smith DH, Trojanowski JQ, McIntosh TK: Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience 1998, 87: 359-369. 10.1016/S0306-4522(98)00142-0
    • (1998) Neuroscience , vol.87 , pp. 359-369
    • Pierce, J.E.1    Smith, D.H.2    Trojanowski, J.Q.3    McIntosh, T.K.4
  • 40
    • 72949092495 scopus 로고    scopus 로고
    • Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of TBI
    • Ziebell JM, Morganti-Kossman MC: Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of TBI. Neurotherapeutics 2010, 7: 22-30. 10.1016/j.nurt.2009.10.016
    • (2010) Neurotherapeutics , vol.7 , pp. 22-30
    • Ziebell, J.M.1    Morganti-Kossman, M.C.2
  • 41
    • 78650189350 scopus 로고    scopus 로고
    • Interleukin-1beta with learning and memory
    • Huang ZB, Sheng GQ: Interleukin-1beta with learning and memory. Neurosci Bull 2010, 26: 455-468. 10.1007/s12264-010-6023-5
    • (2010) Neurosci Bull , vol.26 , pp. 455-468
    • Huang, Z.B.1    Sheng, G.Q.2
  • 42
    • 59249085094 scopus 로고    scopus 로고
    • Evidence for a cytokine model of cognitive function
    • McAfoose J, Baune BT: Evidence for a cytokine model of cognitive function. Neurosci Biobehav Rev 2009, 33: 355-366. 10.1016/j.neubiorev.2008.10.005
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 355-366
    • McAfoose, J.1    Baune, B.T.2
  • 43
    • 27244450900 scopus 로고    scopus 로고
    • Inflammatory genes and neural activity: involvement of immune genes in synaptic function and behavior
    • Tonelli LH, Postolache TT, Sternberg EM: Inflammatory genes and neural activity: involvement of immune genes in synaptic function and behavior. Front Biosci 2005, 10: 675-680. 10.2741/1562
    • (2005) Front Biosci , vol.10 , pp. 675-680
    • Tonelli, L.H.1    Postolache, T.T.2    Sternberg, E.M.3
  • 44
    • 84155162481 scopus 로고    scopus 로고
    • Role of pro-inflammatory cytokines releaed from microglia in neurodegenerative diseases
    • Smith JA, Das A, Ray SK, Banik NL: Role of pro-inflammatory cytokines releaed from microglia in neurodegenerative diseases. Brain Res Bull 2012, 87: 10-20. 10.1016/j.brainresbull.2011.10.004
    • (2012) Brain Res Bull , vol.87 , pp. 10-20
    • Smith, J.A.1    Das, A.2    Ray, S.K.3    Banik, N.L.4
  • 45
    • 52949117520 scopus 로고    scopus 로고
    • Malaise in the water maze: untangling the effects of LPS and IL-1beta on learning and memory
    • Cunningham C, Sanderson DJ: Malaise in the water maze: untangling the effects of LPS and IL-1beta on learning and memory. Brain Behav Immun 2008, 22: 1117-1127. 10.1016/j.bbi.2008.05.007
    • (2008) Brain Behav Immun , vol.22 , pp. 1117-1127
    • Cunningham, C.1    Sanderson, D.J.2
  • 46
    • 0036202161 scopus 로고    scopus 로고
    • Recovery of motor and language abilities after stroke: the contribution of functional imaging
    • Rijntjes M, Weiller C: Recovery of motor and language abilities after stroke: the contribution of functional imaging. Prog Neurobiol 2002, 66: 109-122. 10.1016/S0301-0082(01)00027-2
    • (2002) Prog Neurobiol , vol.66 , pp. 109-122
    • Rijntjes, M.1    Weiller, C.2
  • 47
    • 0024995950 scopus 로고
    • Brain plasticity as a basis for recovery of function in humans
    • Bach-y-Rita P: Brain plasticity as a basis for recovery of function in humans. Neuropsychologia 1990, 28: 547-554. 10.1016/0028-3932(90)90033-K
    • (1990) Neuropsychologia , vol.28 , pp. 547-554
    • Bach-y-Rita, P.1
  • 48
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn BB, Alquier T, Carling D, Hardie DG: AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005, 1: 15-25. 10.1016/j.cmet.2004.12.003
    • (2005) Cell Metab , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 49
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - a unifying system for energy control
    • Carling D: The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem Sci 2004, 29: 18-24. 10.1016/j.tibs.2003.11.005
    • (2004) Trends Biochem Sci , vol.29 , pp. 18-24
    • Carling, D.1
  • 50
    • 84879607026 scopus 로고    scopus 로고
    • Function of the master energy regulator adenosine monophosphate-activated protein kinase in stroke
    • Manwani B, McCullough LD: Function of the master energy regulator adenosine monophosphate-activated protein kinase in stroke. J Neurosci Res 2013, 91: 1018-1029. 10.1002/jnr.23207
    • (2013) J Neurosci Res , vol.91 , pp. 1018-1029
    • Manwani, B.1    McCullough, L.D.2
  • 51
    • 84862493914 scopus 로고    scopus 로고
    • AMP-activated protein kinase: new regulation, new roles?
    • Carling D, Thornton C, Woods A, Sanders MJ: AMP-activated protein kinase: new regulation, new roles? Biochem J 2012, 445: 11-27. 10.1042/BJ20120546
    • (2012) Biochem J , vol.445 , pp. 11-27
    • Carling, D.1    Thornton, C.2    Woods, A.3    Sanders, M.J.4


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