Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Atherosclerosis (MESA)

Maturitas

Volumn 96, Issue , 2017, Pages 95-102

  Zhao, Di ^a   Ouyang, Pamela ^b   de Boer, Ian H ^c   Lutsey, Pamela L ^d   Farag, Youssef M K ^a   Guallar, Eliseo ^a   Siscovick, David S ^e   Post, Wendy S ^a,b   Kalyani, Rita R ^b   Billups, Kevin L ^f   Michos, Erin D ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e NEW YORK ACADEMY OF MEDICINE   (United States)

^f MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Dehydroepiandrosterone; Estradiol; Sex hormone binding globulin; Sex hormones; Testosterone; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; ESTRADIOL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PRASTERONE; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TRIACYLGLYCEROL; VITAMIN D; 25-HYDROXYVITAMIN D;

ADULT; ARTICLE; ATHEROSCLEROSIS; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; ETHNICITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBESITY; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; RISK FACTOR; SMOKING; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; AGED; ANALOGS AND DERIVATIVES; BLOOD; ETHNIC GROUP; METABOLISM;

ADIPOSITY; AGED; ATHEROSCLEROSIS; CROSS-SECTIONAL STUDIES; DEHYDROEPIANDROSTERONE; ESTRADIOL; ETHNIC GROUPS; FEMALE; HUMANS; MALE; MIDDLE AGED; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE; VITAMIN D;

EID: 85003881371     PISSN: 03785122     EISSN: 18734111     Source Type: Journal    
DOI: 10.1016/j.maturitas.2016.11.017     Document Type: Article

References (39)

1. [1] Holick, M.F., Vitamin D deficiency. N. Engl. J. Med. 357:3 (2007), 266–281.
2. [2] Michos, E.D., Misialek, J.R., Selvin, E., Folsom, A.R., Pankow, J.S., Post, W.S., Lutsey, P.L., 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: the ARIC study. Atherosclerosis 241:1 (2015), 12–17.
3. [3] Michos, E.D., Reis, J.P., Post, W.S., Lutsey, P.L., Gottesman, R.F., Mosley, T.H., Sharrett, A.R., Melamed, M.L., 25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: the NHANES-III linked mortality files. Nutrition 28:4 (2012), 367–371.
4. [4] Lutsey, P.L., Michos, E.D., Vitamin D, calcium, and atherosclerotic risk: evidence from serum levels and supplementation studies. Curr. Atheroscler. Rep., 15(1), 2013, 293.
5. [5] Kim, C., Cushman, M., Kleindorfer, D., Lisabeth, L., Redberg, R.F., Safford, M.M., A review of the relationships between endogenous sex steroids and incident ischemic stroke and coronary heart disease events. Curr. Cardiol. Rev. 11:3 (2015), 252–260.
6. [6] Menke, A., Guallar, E., Rohrmann, S., Nelson, W.G., Rifai, N., Kanarek, N., Feinleib, M., Michos, E.D., Dobs, A., Platz, E.A., Sex steroid hormone concentrations and risk of death in US men. Am. J. Epidemiol. 171:5 (2010), 583–592.
7. [7] Hofer, D., Munzker, J., Schwetz, V., Ulbing, M., Hutz, K., Stiegler, P., Zigeuner, R., Pieber, T.R., Muller, H., Obermayer-Pietsch, B., Testicular synthesis and vitamin D action. J. Clin. Endocrinol. Metab. 99:10 (2014), 3766–3773.
8. [8] Zanatta, L., Zamoner, A., Zanatta, A.P., Bouraima-Lelong, H., Delalande, C., Bois, C., Carreau, S., Silva, F.R., Nongenomic and genomic effects of 1alpha, 25(OH)2 vitamin D3 in rat testis. Life Sci. 89:15–16 (2011), 515–523.
9. [9] Chin, K.Y., Ima-Nirwana, S., Wan Ngah, W.Z., Vitamin D is significantly associated with total testosterone and sex hormone-binding globulin in Malaysian men. Aging Male 18:3 (2015), 175–179.
10. [10] Wang, N., Han, B., Li, Q., Chen, Y., Chen, Y., Xia, F., Lin, D., Jensen, M.D., Lu, Y., Vitamin D is associated with testosterone and hypogonadism in Chinese men: results from a cross-sectional SPECT-China study. Reprod. Biol. Endocrinol., 13, 2015, 74.
11. [11] Nimptsch, K., Platz, E.A., Willett, W.C., Giovannucci, E., Association between plasma 25-OH vitamin D and testosterone levels in men. Clin. Endocrinol. (Oxf.) 77:1 (2012), 106–112.
12. [12] Rafiq, R., van Schoor, N.M., Sohl, E., Zillikens, M.C., Oosterwerff, M.M., Schaap, L., Lips, P., de Jongh, R.T., Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men. J. Steroid Biochem. Mol. Biol. 13:November (164) (2016), 11–17 published on-line 2015 [Epub ahead of print].
13. [13] Jorde, R., Grimnes, G., Hutchinson, M.S., Kjaergaard, M., Kamycheva, E., Svartberg, J., Supplementation with vitamin D does not increase serum testosterone levels in healthy males. Horm. Metab. Res. 45:9 (2013), 675–681.
14. [14] Anic, G.M., Albanes, D., Rohrmann, S., Kanarek, N., Nelson, W.G., Bradwin, G., Rifai, N., McGlynn, K.A., Platz, E.A., Mondul, A.M., Association between serum 25-hydroxyvitamin D and serum sex steroid hormones among men in NHANES. Clin. Endocrinol. (Oxf.) 85:2 (2016), 258–266.
15. [15] Laczmanski, L., Lwow, F., Mossakowska, M., Puzianowska-Kuznicka, M., Szwed, M., Kolackov, K., Krzyzanowska-Swiniarska, B., Bar-Andziak, E., Chudek, J., Sloka, N., Milewicz, A., Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236). Gene 559:1 (2015), 73–76.
16. [16] Pilz, S., Frisch, S., Koertke, H., Kuhn, J., Dreier, J., Obermayer-Pietsch, B., Wehr, E., Zittermann, A., Effect of vitamin D supplementation on testosterone levels in men. Horm. Metab. Res. 43:3 (2011), 223–225.
17. [17] Chang, E.M., Kim, Y.S., Won, H.J., Yoon, T.K., Lee, W.S., Association between sex steroids, ovarian reserve, and vitamin D levels in healthy nonobese women. J. Clin. Endocrinol. Metab. 99:7 (2014), 2526–2532.
18. [18] Janssen, H.C., Emmelot-Vonk, M.H., Verhaar, H.J., van der Schouw, Y.T., Determinants of vitamin D status in healthy men and women aged 40–80 years. Maturitas 74:1 (2013), 79–83.
19. [19] He, C., Lin, Z., Robb, S.W., Ezeamama, A.E., Serum Vitamin D levels and polycystic ovary syndrome: a systematic review and meta-analysis. Nutrients 7:6 (2015), 4555–4577.
20. [20] Holick, M.F., Binkley, N.C., Bischoff-Ferrari, H.A., Gordon, C.M., Hanley, D.A., Heaney, R.P., Murad, M.H., Weaver, C.M., Endocrine, S., Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 96:7 (2011), 1911–1930.
21. [21] Reis, J.P., Michos, E.D., Selvin, E., Pankow, J.S., Lutsey, P.L., Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the atherosclerosis risk in communities (ARIC) study. Am. J. Clin. Nutr. 101:6 (2015), 1232–1240.
22. [22] Bild, D.E., Bluemke, D.A., Burke, G.L., Detrano, R., Diez Roux, A.V., Folsom, A.R., Greenland, P., Kronmal, D.R., Jacob, R. Jr., Liu, K., Nelson, J.C., O'Leary, D., Saad, M.F., Shea, S., Szklo, M., Tracy, R.P., Multi-Ethnic Study of Atherosclerosis: objectives and design. Am. J. Epidemiol. 156:9 (2002), 871–881.
23. [23] Inker, L.A., Schmid, C.H., Tighiouart, H., Eckfeldt, J.H., Feldman, H.I., Greene, T., Kusek, J.W., Manzi, J., Van Lente, F., Zhang, Y.L., Coresh, J., Levey, A.S., C.-E. Investigators, Estimating glomerular filtration rate from serum creatinine and cystatin C. N. Engl. J. Med. 367:1 (2012), 20–29.
24. [24] Sachs, M.C., Shoben, A., Levin, G.P., Robinson-Cohen, C., Hoofnagle, A.N., Swords-Jenny, N., Ix, J.H., Budoff, M., Lutsey, P.L., Siscovick, D.S., Kestenbaum, B., de Boer, I.H., Estimating mean annual 25-hydroxyvitamin D concentrations from single measurements: the Multi-Ethnic Study of Atherosclerosis. Am. J. Clin. Nutr. 97:6 (2013), 1243–1251.
25. [25] Phinney, K.W., Bedner, M., Tai, S.S., Vamathevan, V.V., Sander, L.C., Sharpless, K.E., Wise, S.A., Yen, J.H., Schleicher, R.L., Chaudhary-Webb, M., Pfeiffer, C.M., Betz, J.M., Coates, P.M., Picciano, M.F., Development and certification of a standard reference material for vitamin D metabolites in human serum. Anal. Chem. 84:2 (2012), 956–962.
26. [26] Kalyani, R.R., Franco, M., Dobs, A.S., Ouyang, P., Vaidya, D., Bertoni, A., Gapstur, S.M., Golden, S.H., The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women. J. Clin. Endocrinol. Metab. 94:11 (2009), 4127–4135.
27. [27] Sodergard, R., Backstrom, T., Shanbhag, V., Carstensen, H., Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J. Steroid Biochem. 16:6 (1982), 801–810.
28. [28] Vermeulen, A., Verdonck, L., Kaufman, J.M., A critical evaluation of simple methods for the estimation of free testosterone in serum. J. Clin. Endocrinol. Metab. 84:10 (1999), 3666–3672.
29. [29] Lerchbaum, E., Pilz, S., Trummer, C., Rabe, T., Schenk, M., Heijboer, A.C., Obermayer-Pietsch, B., Serum vitamin D levels and hypogonadism in men. Andrology 2:5 (2014), 748–754.
30. [30] Dandona, P., Rosenberg, M.T., A practical guide to male hypogonadism in the primary care setting. Int. J. Clin. Pract. 64:6 (2010), 682–696.
31. [31] Bhasin, S., Cunningham, G.R., Hayes, F.J., Matsumoto, A.M., Snyder, P.J., Swerdloff, R.S., Montori, V.M., Task Force, E.S., Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 95:6 (2010), 2536–2559.
32. [32] Pop, L.C., Shapses, S.A., Chang, B., Sun, W., Wang, X., Vitamin D-binding protein in healthy pre- and postmenopausal women: relationship with estradiol concentrations. Endocr. Pract. 21:8 (2015), 936–942.
33. [33] Selby, C., Sex hormone binding globulin: origin, function and clinical significance. Ann. Clin. Biochem. 27:Pt. 6 (1990), 532–541.
34. [34] Golden, S.H., Dobs, A.S., Vaidya, D., Szklo, M., Gapstur, S., Kopp, P., Liu, K., Ouyang, P., Endogenous sex hormones and glucose tolerance status in postmenopausal women. J. Clin. Endocrinol. Metab. 92:4 (2007), 1289–1295.
35. [35] Sutton-Tyrrell, K., Wildman, R.P., Matthews, K.A., Chae, C., Lasley, B.L., Brockwell, S., Pasternak, R.C., Lloyd-Jones, D., Sowers, M.F., Torrens, J.I., Investigators, S., Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN). Circulation 111:10 (2005), 1242–1249.
36. [36] Mutt, S.J., Hypponen, E., Saarnio, J., Jarvelin, M.R., Herzig, K.H., Vitamin D and adipose tissue-more than storage. Front. Physiol., 5, 2014, 228.
37. [37] Haffner, S.M., Katz, M.S., Stern, M.P., Dunn, J.F., Relationship of sex hormone binding globulin to overall adiposity and body fat distribution in a biethnic population. Int. J. Obes. 13:1 (1989), 1–9.
38. [38] Cheng, C.H., Ho, C.C., Yang, C.F., Huang, Y.C., Lai, C.H., Liaw, Y.P., Waist-to-hip ratio is a better anthropometric index than body mass index for predicting the risk of type 2 diabetes in Taiwanese population. Nutr. Res. 30:9 (2010), 585–593.
39. [39] Berman, D.M., Rodrigues, L.M., Nicklas, B.J., Ryan, A.S., Dennis, K.E., Goldberg, A.P., Racial disparities in metabolism, central obesity, and sex hormone-binding globulin in postmenopausal women. J. Clin. Endocrinol. Metab. 86:1 (2001), 97–103.