메뉴 건너뛰기




Volumn 33, Issue , 2017, Pages 326-330

The Ala55Val and -866G>A polymorphisms of the UCP2 gene could be biomarkers for weight loss in patients who had Roux-en-Y gastric bypass

Author keywords

Bariatric surgery; Biomarker; Obesity; UCP2 polymorphism; Weight loss

Indexed keywords

ALANINE; BIOLOGICAL MARKER; GLYCINE; UNCOUPLING PROTEIN 2; VALINE; UCP2 PROTEIN, HUMAN;

EID: 85003550254     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2016.07.020     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 77149155340 scopus 로고    scopus 로고
    • Bariatric surgery and taste: novel mechanisms of weight loss
    • [1] Miras, A.D., le Roux, C.W., Bariatric surgery and taste: novel mechanisms of weight loss. Curr Opin Gastroenterol 26 (2010), 140–145.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 140-145
    • Miras, A.D.1    le Roux, C.W.2
  • 4
    • 79956189451 scopus 로고    scopus 로고
    • Short versus long Roux-limb length in Roux-en-Y gastric bypass surgery for the treatment of morbid and super obesity: a systematic review of the literature
    • [4] Orci, L., Chilcott, M., Huber, O., Short versus long Roux-limb length in Roux-en-Y gastric bypass surgery for the treatment of morbid and super obesity: a systematic review of the literature. Obes Surg 21 (2011), 797–804.
    • (2011) Obes Surg , vol.21 , pp. 797-804
    • Orci, L.1    Chilcott, M.2    Huber, O.3
  • 5
    • 33748414619 scopus 로고    scopus 로고
    • Micronutrient deficiencies and bariatric surgery
    • [5] Kushner, R.F., Micronutrient deficiencies and bariatric surgery. Curr Opin Endocrinol Diab 13 (2006), 405–411.
    • (2006) Curr Opin Endocrinol Diab , vol.13 , pp. 405-411
    • Kushner, R.F.1
  • 7
    • 79960844745 scopus 로고    scopus 로고
    • High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery
    • [7] Still, C.D., Wood, G.C., Chu, X., Erdman, R., Manney, C.H., Benotti, P.N., et al. High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery. Obesity (Silver Spring) 19 (2011), 1676–1683.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 1676-1683
    • Still, C.D.1    Wood, G.C.2    Chu, X.3    Erdman, R.4    Manney, C.H.5    Benotti, P.N.6
  • 9
    • 33749666308 scopus 로고    scopus 로고
    • Uncoupling proteins, dietary fat and the metabolic syndrome
    • [9] Fisler, J.S., Warden, C.H., Uncoupling proteins, dietary fat and the metabolic syndrome. Nutr Metab (Lond), 3, 2006, 38.
    • (2006) Nutr Metab (Lond) , vol.3 , pp. 38
    • Fisler, J.S.1    Warden, C.H.2
  • 10
    • 0034650763 scopus 로고    scopus 로고
    • The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
    • [10] Ricquier, D., Bouillaud, F., The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem J 345 (2000), 161–179.
    • (2000) Biochem J , vol.345 , pp. 161-179
    • Ricquier, D.1    Bouillaud, F.2
  • 11
    • 0347123564 scopus 로고    scopus 로고
    • Role of UCP2 and UCP3 in nutrition and obesity
    • [11] Nagy, T.R., Blaylock, M.L., Garvey, W.T., Role of UCP2 and UCP3 in nutrition and obesity. Nutrition 20 (2004), 139–144.
    • (2004) Nutrition , vol.20 , pp. 139-144
    • Nagy, T.R.1    Blaylock, M.L.2    Garvey, W.T.3
  • 12
    • 35748967587 scopus 로고    scopus 로고
    • Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding
    • [12] Chen, H.H., Lee, W.J., Wang, W., Huang, M.T., Lee, Y.C., Pan, W.H., Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding. Obes Surg 17 (2007), 926–933.
    • (2007) Obes Surg , vol.17 , pp. 926-933
    • Chen, H.H.1    Lee, W.J.2    Wang, W.3    Huang, M.T.4    Lee, Y.C.5    Pan, W.H.6
  • 13
    • 84875684855 scopus 로고    scopus 로고
    • UCP2–UCP866 G/A, Ala55Val and UCP3 -55 C/T polymorphisms in association with obesity susceptibility—a meta-analysis study
    • [13] Qian, L., Xu, K., Xu, X., Gu, R., Shan, S., Yang, T., UCP2–UCP866 G/A, Ala55Val and UCP3 -55 C/T polymorphisms in association with obesity susceptibility—a meta-analysis study. PLoS One, 8, 2013, e58939.
    • (2013) PLoS One , vol.8 , pp. e58939
    • Qian, L.1    Xu, K.2    Xu, X.3    Gu, R.4    Shan, S.5    Yang, T.6
  • 14
    • 0034972150 scopus 로고    scopus 로고
    • A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
    • [14] Esterbauer, H., Schneitler, C., Oberkofler, H., Ebenbichler, C., Paulweber, B., Sandhofer, F., et al. A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet 28 (2001), 178–183.
    • (2001) Nat Genet , vol.28 , pp. 178-183
    • Esterbauer, H.1    Schneitler, C.2    Oberkofler, H.3    Ebenbichler, C.4    Paulweber, B.5    Sandhofer, F.6
  • 15
    • 79951895658 scopus 로고    scopus 로고
    • The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
    • [15] Pena, S.D., Di Pietro, G., Fuchshuber-Moraes, M., Genro, J.P., Hutz, M.H., Kehdy Fde, S., et al. The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected. PLoS One, 6, 2011, e17063.
    • (2011) PLoS One , vol.6 , pp. e17063
    • Pena, S.D.1    Di Pietro, G.2    Fuchshuber-Moraes, M.3    Genro, J.P.4    Hutz, M.H.5    Kehdy Fde, S.6
  • 16
    • 23044461195 scopus 로고    scopus 로고
    • The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study
    • [16] Yu, X., Jacobs, D.R. Jr., Schreiner, P.J., Gross, M.D., Steffes, M.W., Fornage, M., The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study. Clin Chem 51 (2005), 1451–1456.
    • (2005) Clin Chem , vol.51 , pp. 1451-1456
    • Yu, X.1    Jacobs, D.R.2    Schreiner, P.J.3    Gross, M.D.4    Steffes, M.W.5    Fornage, M.6
  • 17
    • 77952559481 scopus 로고    scopus 로고
    • The on–off switches of the mitochondrial uncoupling proteins
    • [17] Azzu, V., Brand, M.D., The on–off switches of the mitochondrial uncoupling proteins. Trends Biochem Sci 35 (2010), 298–307.
    • (2010) Trends Biochem Sci , vol.35 , pp. 298-307
    • Azzu, V.1    Brand, M.D.2
  • 18
    • 79960534188 scopus 로고    scopus 로고
    • The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications
    • [18] Souza, B.M., Assmann, T.S., Kliemann, L.M., Gross, J.L., Canani, L.H., Crispim, D., The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications. Arq Bras Endocrinol Metabol 55 (2011), 239–248.
    • (2011) Arq Bras Endocrinol Metabol , vol.55 , pp. 239-248
    • Souza, B.M.1    Assmann, T.S.2    Kliemann, L.M.3    Gross, J.L.4    Canani, L.H.5    Crispim, D.6
  • 19
    • 27744550916 scopus 로고    scopus 로고
    • Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians
    • [19] Kovacs, P., Ma, L., Hanson, R.L., Franks, P., Stumvoll, M., Bogardus, C., et al. Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians. Diabetologia 48 (2005), 2292–2295.
    • (2005) Diabetologia , vol.48 , pp. 2292-2295
    • Kovacs, P.1    Ma, L.2    Hanson, R.L.3    Franks, P.4    Stumvoll, M.5    Bogardus, C.6
  • 21
    • 0034103005 scopus 로고    scopus 로고
    • Uncoupling protein homologs: emerging views of physiological function
    • [21] Adams, S.H., Uncoupling protein homologs: emerging views of physiological function. J Nutr 130 (2000), 711–714.
    • (2000) J Nutr , vol.130 , pp. 711-714
    • Adams, S.H.1
  • 22
    • 84871417302 scopus 로고    scopus 로고
    • An association between -866 G/A polymorphism in the promoter of UCP2 and obesity: a meta-analysis
    • [22] Liu, L., Zhao, X., Kang, S., Zhang, D., An association between -866 G/A polymorphism in the promoter of UCP2 and obesity: a meta-analysis. Gene 514 (2013), 41–47.
    • (2013) Gene , vol.514 , pp. 41-47
    • Liu, L.1    Zhao, X.2    Kang, S.3    Zhang, D.4
  • 23
    • 0037145722 scopus 로고    scopus 로고
    • Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the metabolic syndrome
    • [23] Rosmond, R., Bouchard, C., Bjorntorp, P., Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the metabolic syndrome. Biochim Biophys Acta 1588 (2002), 103–105.
    • (2002) Biochim Biophys Acta , vol.1588 , pp. 103-105
    • Rosmond, R.1    Bouchard, C.2    Bjorntorp, P.3
  • 24
    • 0031868313 scopus 로고    scopus 로고
    • No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure
    • [24] Klannemark, M., Orho, M., Groop, L., No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure. Eur J Endocrinol 139 (1998), 217–223.
    • (1998) Eur J Endocrinol , vol.139 , pp. 217-223
    • Klannemark, M.1    Orho, M.2    Groop, L.3
  • 25
    • 77949653045 scopus 로고    scopus 로고
    • A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians
    • [25] Srivastava, N., Prakash, J., Lakhan, R., Agarwal, C.G., Pant, D.C., Mittal, B., A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians. Mol Cell Biochem 337 (2010), 293–298.
    • (2010) Mol Cell Biochem , vol.337 , pp. 293-298
    • Srivastava, N.1    Prakash, J.2    Lakhan, R.3    Agarwal, C.G.4    Pant, D.C.5    Mittal, B.6
  • 26
    • 0344082604 scopus 로고    scopus 로고
    • Variants of uncoupling protein-2 gene and obesity: interaction with peroxisome proliferator-activated receptorgamma2
    • [26] Mancini, F.P., Sabatino, L., Colantuoni, V., Pasanisi, F., Finelli, C., Contaldo, F., et al. Variants of uncoupling protein-2 gene and obesity: interaction with peroxisome proliferator-activated receptorgamma2. Clin Endocrinol (Oxf) 59 (2003), 817–822.
    • (2003) Clin Endocrinol (Oxf) , vol.59 , pp. 817-822
    • Mancini, F.P.1    Sabatino, L.2    Colantuoni, V.3    Pasanisi, F.4    Finelli, C.5    Contaldo, F.6
  • 27
    • 78149259769 scopus 로고    scopus 로고
    • Association study of the -866 G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study
    • [27] Heidari, J., Akrami, S.M., Heshmat, R., Amiri, P., Fakhrzadeh, H., Pajouhi, M., Association study of the -866 G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study. Arch Iran Med 13 (2010), 384–390.
    • (2010) Arch Iran Med , vol.13 , pp. 384-390
    • Heidari, J.1    Akrami, S.M.2    Heshmat, R.3    Amiri, P.4    Fakhrzadeh, H.5    Pajouhi, M.6
  • 28
    • 34250354410 scopus 로고    scopus 로고
    • Effects of genetic polymorphisms of UCP2 and UCP3 on very low calorie diet-induced body fat reduction in Korean female subjects
    • [28] Yoon, Y., Park, B.L., Cha, M.H., Kim, K.S., Cheong, H.S., Shin, H.D., Effects of genetic polymorphisms of UCP2 and UCP3 on very low calorie diet-induced body fat reduction in Korean female subjects. Biochem Biophys Res Commun 359 (2007), 451–456.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 451-456
    • Yoon, Y.1    Park, B.L.2    Cha, M.H.3    Kim, K.S.4    Cheong, H.S.5    Shin, H.D.6
  • 29
    • 0036196046 scopus 로고    scopus 로고
    • Racial differences in the relation between uncoupling protein genes and resting energy expenditure
    • [29] Kimm, S.Y., Glynn, N.W., Aston, C.E., Damcott, C.M., Poehlman, E.T., Daniels, S.R., et al. Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr 75 (2002), 714–719.
    • (2002) Am J Clin Nutr , vol.75 , pp. 714-719
    • Kimm, S.Y.1    Glynn, N.W.2    Aston, C.E.3    Damcott, C.M.4    Poehlman, E.T.5    Daniels, S.R.6
  • 30
    • 7344220905 scopus 로고    scopus 로고
    • Association between uncoupling protein polymorphisms (UCP2–UCP3) and energy metabolism/obesity in Pima Indians
    • [30] Walder, K., Norman, R.A., Hanson, R.L., Schrauwen, P., Neverova, M., Jensinson, C.P., et al. Association between uncoupling protein polymorphisms (UCP2–UCP3) and energy metabolism/obesity in Pima Indians. Hum Mol Genet 7 (1998), 1431–1435.
    • (1998) Hum Mol Genet , vol.7 , pp. 1431-1435
    • Walder, K.1    Norman, R.A.2    Hanson, R.L.3    Schrauwen, P.4    Neverova, M.5    Jensinson, C.P.6
  • 31
    • 84871247076 scopus 로고    scopus 로고
    • UCP2 I/D modulated change in BMI during a lifestyle modification intervention study in Japanese subjects
    • [31] Mutombo, P.B., Yamasaki, M., Shiwaku, K., UCP2 I/D modulated change in BMI during a lifestyle modification intervention study in Japanese subjects. Genet Test Mol Biomarkers 17 (2013), 16–20.
    • (2013) Genet Test Mol Biomarkers , vol.17 , pp. 16-20
    • Mutombo, P.B.1    Yamasaki, M.2    Shiwaku, K.3
  • 32
    • 84897102624 scopus 로고    scopus 로고
    • Bioelectrical impedance vector analysis in obese women before and after bariatric surgery: changes in body composition
    • [32] Nicoletti, C.F., Camelo, J.S. Jr., dos Santos, J.E., Marchini, J.S., Slagado, W. Jr., Nonino, C.B., Bioelectrical impedance vector analysis in obese women before and after bariatric surgery: changes in body composition. Nutrition 30 (2014), 569–574.
    • (2014) Nutrition , vol.30 , pp. 569-574
    • Nicoletti, C.F.1    Camelo, J.S.2    dos Santos, J.E.3    Marchini, J.S.4    Slagado, W.5    Nonino, C.B.6
  • 33
    • 84960446048 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians
    • [33] Kim, S., Myers, L., Ravussin, E., Cherry, K.E., Jazwinski, S.M., Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. Biogerontology 17 (2016), 725–736.
    • (2016) Biogerontology , vol.17 , pp. 725-736
    • Kim, S.1    Myers, L.2    Ravussin, E.3    Cherry, K.E.4    Jazwinski, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.