-
1
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
82
-
Hutter G, Nowak D, Mossner M, Ganepola S, Mussig A, Allers K, Schneider T, Hofmann J, Kucherer C, Blau O, Blau IW, Hofmann WK, Thiel E. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med. 2009;360(7):692-8.82. doi: 10.1056/NEJMoa0802905
-
(2009)
N Engl J Med
, vol.360
, Issue.7
, pp. 692-698
-
-
Hutter, G1
Nowak, D2
Mossner, M3
Ganepola, S4
Mussig, A5
Allers, K6
Schneider, T7
Hofmann, J8
Kucherer, C9
Blau, O10
Blau, IW11
Hofmann, WK12
Thiel, E.13
-
2
-
-
84922394525
-
More on shift of HIV tropism in stem-cell transplantation with CCR5 delta32/delta32 mutation
-
21
-
Hutter G. More on shift of HIV tropism in stem-cell transplantation with CCR5 delta32/delta32 mutation. N Engl J Med. 2014;371(25):2437-8.21. doi: 10.1056/NEJMc1412279#SA1
-
(2014)
N Engl J Med
, vol.371
, Issue.25
, pp. 2437-2438
-
-
Hutter, G.1
-
3
-
-
0037561928
-
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
-
88
-
Brenchley JM, Karandikar NJ, Betts MR, Ambrozak DR, Hill BJ, Crotty LE, Casazza JP, Kuruppu J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood. 2003;101(7):2711-20.88. doi: 10.1182/blood-2002-07-2103
-
(2003)
Blood
, vol.101
, Issue.7
, pp. 2711-2720
-
-
Brenchley, JM1
Karandikar, NJ2
Betts, MR3
Ambrozak, DR4
Hill, BJ5
Crotty, LE6
Casazza, JP7
Kuruppu, J8
Migueles, SA9
Connors, M10
Roederer, M11
Douek, DC12
Koup, RA.13
-
4
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
84
-
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006;443(7109):350-4.84. doi: 10.1038/nature05115
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 350-354
-
-
Day, CL1
Kaufmann, DE2
Kiepiela, P3
Brown, JA4
Moodley, ES5
Reddy, S6
Mackey, EW7
Miller, JD8
Leslie, AJ9
DePierres, C10
Mncube, Z11
Duraiswamy, J12
Zhu, B13
Eichbaum, Q14
Altfeld, M15
Wherry, EJ16
Coovadia, HM17
Goulder, PJ18
Klenerman, P19
Ahmed, R20
Freeman, GJ21
Walker, BD.22
more..
-
5
-
-
84893830170
-
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
-
25
-
Fletcher CV, Staskus K, Wietgrefe SW, Rothenberger M, Reilly C, Chipman JG, Beilman GJ, Khoruts A, Thorkelson A, Schmidt TE, Anderson J, Perkey K, Stevenson M, Perelson AS, Douek DC, Haase AT, Schacker TW. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci U S A. 2014;111(6):2307-12.25. doi: 10.1073/pnas.1318249111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.6
, pp. 2307-2312
-
-
Fletcher, CV1
Staskus, K2
Wietgrefe, SW3
Rothenberger, M4
Reilly, C5
Chipman, JG6
Beilman, GJ7
Khoruts, A8
Thorkelson, A9
Schmidt, TE10
Anderson, J11
Perkey, K12
Stevenson, M13
Perelson, AS14
Douek, DC15
Haase, AT16
Schacker, TW.17
-
6
-
-
84877278315
-
Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation
-
51
-
Henrich TJ, Hu Z, Li JZ, Sciaranghella G, Busch MP, Keating SM, Gallien S, Lin NH, Giguel FF, Lavoie L, Ho VT, Armand P, Soiffer RJ, Sagar M, Lacasce AS, Kuritzkes DR. Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis. 2013;207(11):1694-702.51. doi: 10.1093/infdis/jit086
-
(2013)
J Infect Dis
, vol.207
, Issue.11
, pp. 1694-1702
-
-
Henrich, TJ1
Hu, Z2
Li, JZ3
Sciaranghella, G4
Busch, MP5
Keating, SM6
Gallien, S7
Lin, NH8
Giguel, FF9
Lavoie, L10
Ho, VT11
Armand, P12
Soiffer, RJ13
Sagar, M14
Lacasce, AS15
Kuritzkes, DR.16
-
7
-
-
58149382617
-
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy
-
78
-
Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, Hunt PW, Hoh R, Stramer SL, Linnen JM, McCune JM, Martin JN, Busch MP, Deeks SG. Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. J Virol. 2009;83(1):329-35.78. doi: 10.1128/jvi.01763-08
-
(2009)
J Virol
, vol.83
, Issue.1
, pp. 329-335
-
-
Hatano, H1
Delwart, EL2
Norris, PJ3
Lee, TH4
Dunn-Williams, J5
Hunt, PW6
Hoh, R7
Stramer, SL8
Linnen, JM9
McCune, JM10
Martin, JN11
Busch, MP12
Deeks, SG.13
-
8
-
-
40049094957
-
Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy
-
76
-
Pereyra F, Addo MM, Kaufmann DE, Liu Y, Miura T, Rathod A, Baker B, Trocha A, Rosenberg R, Mackey E, Ueda P, Lu Z, Cohen D, Wrin T, Petropoulos CJ, Rosenberg ES, Walker BD. Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J Infect Dis. 2008;197(4):563-71.76. doi: 10.1086/526786
-
(2008)
J Infect Dis
, vol.197
, Issue.4
, pp. 563-571
-
-
Pereyra, F1
Addo, MM2
Kaufmann, DE3
Liu, Y4
Miura, T5
Rathod, A6
Baker, B7
Trocha, A8
Rosenberg, R9
Mackey, E10
Ueda, P11
Lu, Z12
Cohen, D13
Wrin, T14
Petropoulos, CJ15
Rosenberg, ES16
Walker, BD.17
-
9
-
-
84875985311
-
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
-
Saez-Cirion A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, Potard V, Versmisse P, Melard A, Prazuck T, Descours B, Guergnon J, Viard JP, Boufassa F, Lambotte O, Goujard C, Meyer L, Costagliola D, Venet A, Pancino G, Autran B, Rouzioux C. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog. 2013;9(3):e1003211.60. doi: 10.1371/journal.ppat.1003211
-
(2013)
PLoS Pathog
, vol.9
, Issue.3
, pp. e100321160
-
-
Saez-Cirion, A1
Bacchus, C2
Hocqueloux, L3
Avettand-Fenoel, V4
Girault, I5
Lecuroux, C6
Potard, V7
Versmisse, P8
Melard, A9
Prazuck, T10
Descours, B11
Guergnon, J12
Viard, JP13
Boufassa, F14
Lambotte, O15
Goujard, C16
Meyer, L17
Costagliola, D18
Venet, A19
Pancino, G20
Autran, B21
Rouzioux, C.22
more..
-
10
-
-
39349088126
-
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy
-
95
-
Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis. 2008;197(1):126-33.95. doi: 10.1086/524143
-
(2008)
J Infect Dis
, vol.197
, Issue.1
, pp. 126-133
-
-
Hunt, PW1
Brenchley, J2
Sinclair, E3
McCune, JM4
Roland, M5
Page-Shafer, K6
Hsue, P7
Emu, B8
Krone, M9
Lampiris, H10
Douek, D11
Martin, JN12
Deeks, SG.13
-
11
-
-
79955962732
-
HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis
-
70
-
Sauce D, Larsen M, Fastenackels S, Pauchard M, Ait-Mohand H, Schneider L, Guihot A, Boufassa F, Zaunders J, Iguertsira M, Bailey M, Gorochov G, Duvivier C, Carcelain G, Kelleher AD, Simon A, Meyer L, Costagliola D, Deeks SG, Lambotte O, Autran B, Hunt PW, Katlama C, Appay V. HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis. Blood. 2011;117(19):5142-51.70. doi: 10.1182/blood-2011-01-331306
-
(2011)
Blood
, vol.117
, Issue.19
, pp. 5142-5151
-
-
Sauce, D1
Larsen, M2
Fastenackels, S3
Pauchard, M4
Ait-Mohand, H5
Schneider, L6
Guihot, A7
Boufassa, F8
Zaunders, J9
Iguertsira, M10
Bailey, M11
Gorochov, G12
Duvivier, C13
Carcelain, G14
Kelleher, AD15
Simon, A16
Meyer, L17
Costagliola, D18
Deeks, SG19
Lambotte, O20
Autran, B21
Hunt, PW22
Katlama, C23
Appay, V.24
more..
-
12
-
-
84895487305
-
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
-
65
-
Tebas P, Stein D, Tang WW, Frank I, Wang SQ, Lee G, Spratt SK, Surosky RT, Giedlin MA, Nichol G, Holmes MC, Gregory PD, Ando DG, Kalos M, Collman RG, Binder-Scholl G, Plesa G, Hwang WT, Levine BL, June CH. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med. 2014;370(10):901-10.65. doi: 10.1056/NEJMoa1300662
-
(2014)
N Engl J Med
, vol.370
, Issue.10
, pp. 901-910
-
-
Tebas, P1
Stein, D2
Tang, WW3
Frank, I4
Wang, SQ5
Lee, G6
Spratt, SK7
Surosky, RT8
Giedlin, MA9
Nichol, G10
Holmes, MC11
Gregory, PD12
Ando, DG13
Kalos, M14
Collman, RG15
Binder-Scholl, G16
Plesa, G17
Hwang, WT18
Levine, BL19
June, CH.20
more..
-
13
-
-
84979860400
-
Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Delta32
-
07
-
Henrich TJ, Hanhauser E, Hu Z, Stellbrink HJ, Noah C, Martin JN, Deeks SG, Kuritzkes DR, Pereyra F. Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Delta32. AIDS. 2015;29(8):867-76.07. doi: 10.1097/qad.0000000000000629
-
(2015)
AIDS
, vol.29
, Issue.8
, pp. 867-876
-
-
Henrich, TJ1
Hanhauser, E2
Hu, Z3
Stellbrink, HJ4
Noah, C5
Martin, JN6
Deeks, SG7
Kuritzkes, DR8
Pereyra, F.9
-
14
-
-
84910010874
-
Soluble markers of inflammation and coagulation, but not T-cell activation, are predictors of non-AIDS-defining morbid events during suppressive antiretroviral treatment
-
Tenorio AR, Zheng Y, Bosch RJ, Krishnan S, Rodriguez B, Hunt PW, Plants J, Seth A, Wilson CC, Deeks SG, Lederman MM, Landay AL. Soluble markers of inflammation and coagulation, but not T-cell activation, are predictors of non-AIDS-defining morbid events during suppressive antiretroviral treatment. J Infect Dis. 2014.73. doi: 10.1093/infdis/jiu254
-
(2014)
J Infect Dis
, vol.73
-
-
Tenorio, AR1
Zheng, Y2
Bosch, RJ3
Krishnan, S4
Rodriguez, B5
Hunt, PW6
Plants, J7
Seth, A8
Wilson, CC9
Deeks, SG10
Lederman, MM11
Landay, AL.12
-
15
-
-
84901686066
-
HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality
-
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality. PLoS Pathog. 2014;10(5):e1004078.17. doi: 10.1371/journal.ppat.1004078
-
(2014)
PLoS Pathog
, vol.10
, Issue.5
, pp. e100407817
-
-
Serrano-Villar, S1
Sainz, T2
Lee, SA3
Hunt, PW4
Sinclair, E5
Shacklett, BL6
Ferre, AL7
Hayes, TL8
Somsouk, M9
Hsue, PY10
Van Natta, ML11
Meinert, CL12
Lederman, MM13
Hatano, H14
Jain, V15
Huang, Y16
Hecht, FM17
Martin, JN18
McCune, JM19
Moreno, S20
Deeks, SG.21
more..
-
16
-
-
80052882129
-
Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells
-
95
-
Lederman MM, Calabrese L, Funderburg NT, Clagett B, Medvik K, Bonilla H, Gripshover B, Salata RA, Taege A, Lisgaris M, McComsey GA, Kirchner E, Baum J, Shive C, Asaad R, Kalayjian RC, Sieg SF, Rodriguez B. Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells. J Infect Dis. 2011;204(8):1217-26.95. doi: 10.1093/infdis/jir507
-
(2011)
J Infect Dis
, vol.204
, Issue.8
, pp. 1217-1226
-
-
Lederman, MM1
Calabrese, L2
Funderburg, NT3
Clagett, B4
Medvik, K5
Bonilla, H6
Gripshover, B7
Salata, RA8
Taege, A9
Lisgaris, M10
McComsey, GA11
Kirchner, E12
Baum, J13
Shive, C14
Asaad, R15
Kalayjian, RC16
Sieg, SF17
Rodriguez, B.18
-
17
-
-
27944487152
-
Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count
-
69
-
Schacker TW, Reilly C, Beilman GJ, Taylor J, Skarda D, Krason D, Larson M, Haase AT. Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count. AIDS. 2005;19(18):2169-71.69.
-
(2005)
AIDS
, vol.19
, Issue.18
, pp. 2169-2171
-
-
Schacker, TW1
Reilly, C2
Beilman, GJ3
Taylor, J4
Skarda, D5
Krason, D6
Larson, M7
Haase, AT.8
-
18
-
-
84901675589
-
Inflammatory Cytokines Drive CD4+ T-Cell Cycling and Impaired Responsiveness to Interleukin 7: Implications for Immune Failure in HIV Disease
-
Shive CL, Mudd JC, Funderburg NT, Sieg SF, Kyi B, Bazdar DA, Mangioni D, Gori A, Jacobson JM, Brooks AD, Hardacre J, Ammori J, Estes JD, Schacker TW, Rodriguez B, Lederman MM. Inflammatory Cytokines Drive CD4+ T-Cell Cycling and Impaired Responsiveness to Interleukin 7: Implications for Immune Failure in HIV Disease. J Infect Dis. 2014.97. doi: 10.1093/infdis/jiu125
-
(2014)
J Infect Dis
, vol.97
-
-
Shive, CL1
Mudd, JC2
Funderburg, NT3
Sieg, SF4
Kyi, B5
Bazdar, DA6
Mangioni, D7
Gori, A8
Jacobson, JM9
Brooks, AD10
Hardacre, J11
Ammori, J12
Estes, JD13
Schacker, TW14
Rodriguez, B15
Lederman, MM.16
-
19
-
-
84902281875
-
Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection
-
Hunt PW, Sinclair E, Rodriguez B, Shive C, Clagett B, Funderburg N, Robinson J, Huang Y, Epling L, Martin JN, Deeks SG, Meinert CL, Van Natta M, Jabs DA, Lederman MM. Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection. J Infect Dis. 2014.34. doi: 10.1093/infdis/jiu238
-
(2014)
J Infect Dis
, vol.34
-
-
Hunt, PW1
Sinclair, E2
Rodriguez, B3
Shive, C4
Clagett, B5
Funderburg, N6
Robinson, J7
Huang, Y8
Epling, L9
Martin, JN10
Deeks, SG11
Meinert, CL12
Van Natta, M13
Jabs, DA14
Lederman, MM.15
-
20
-
-
84922515339
-
Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy
-
69
-
May MT, Gompels M, Delpech V, Porter K, Orkin C, Kegg S, Hay P, Johnson M, Palfreeman A, Gilson R, Chadwick D, Martin F, Hill T, Walsh J, Post F, Fisher M, Ainsworth J, Jose S, Leen C, Nelson M, Anderson J, Sabin C. Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy. AIDS. 2014;28(8):1193-202.69. doi: 10.1097/qad.0000000000000243
-
(2014)
AIDS
, vol.28
, Issue.8
, pp. 1193-1202
-
-
May, MT1
Gompels, M2
Delpech, V3
Porter, K4
Orkin, C5
Kegg, S6
Hay, P7
Johnson, M8
Palfreeman, A9
Gilson, R10
Chadwick, D11
Martin, F12
Hill, T13
Walsh, J14
Post, F15
Fisher, M16
Ainsworth, J17
Jose, S18
Leen, C19
Nelson, M20
Anderson, J21
Sabin, C.22
more..
|