MyD88 and TRIF mediate divergent inflammatory and regenerative responses to skeletal muscle ischemia

Physiological Reports

Volumn 2, Issue 5, 2014, Pages

  Sachdev, Ulka ^a   Cui, Xiangdong ^a   Xu, Jia ^a   Xu, Jun ^a   Tzeng, Edith ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Innate immunity; Muscle ischemia; PAD; Toll like receptors

Indexed keywords

INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUSION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMORAL ARTERY; GENE INACTIVATION; HINDLIMB; HISTOLOGY; INFLAMMATION; MALE; MOUSE; MUSCLE ISCHEMIA; MYOBLAST; NONHUMAN; REGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; TRANSGENIC MOUSE;

EID: 85002584467     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12006     Document Type: Article

References (39)

1. Baumgartner, I., A. Pieczek, O. Manor, R. Blair, M. Kearney, K. Walsh, et al. 1998. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 97:1114-1123.
2. Van Beijnum, J. R., R. P. Dings, E. van der Linden, B. M. Zwaans, F. C. Ramaekers, K. H. Mayo, et al. 2006. Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. Blood 108:2339-2348.
3. Bondesen, B. A., S. T. Mills, K. M. Kegley, and G. K. Pavlath. 2004. The COX-2 pathway is essential during early stages of skeletal muscle regeneration. Am. J. Physiol.-Cell Physiol. 287:C475-C483.
4. Charge, S. B., and M. A. Rudnicki. 2004. Cellular and molecular regulation of muscle regeneration. Physiol. Rev. 84:209-238.
5. Chavakis, E., A. Hain, M. Vinci, G. Carmona, M. E. Bianchi, P. Vajkoczy, et al. 2007. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ. Res. 100:204-212.
6. Contreras-Shannon, V., O. Ochoa, S. M. Reyes-Reyna, D. Sun, J. E. Michalek, W. A. Kuziel, et al. 2007. Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/-mice following ischemic injury. Am. J. Physiol. Cell Physiol. 292:C953-C967.
7. De Mori, R., S. Straino, A. Di Carlo, A. Mangoni, G. Pompilio, R. Palumbo, et al. 2007. Multiple effects of high mobility group box protein 1 in skeletal muscle regeneration. Arterioscler. Thromb. Vasc. Biol. 27:2377-2383.
8. Frost, R. A., G. J. Nystrom, and C. H. Lang. 2006. Multiple toll-like receptor ligands induce an IL-6 transcriptional response in skeletal myocytes. Am. J. Physiol.-Reg. Integ. Comp. Physiol. 290:R773-R784.
9. Haddad, F., F. Zaldivar, D. M. Cooper, and G. R. Adams. 2005. IL-6-induced skeletal muscle atrophy. J. Appl. Physiol. 98:911-917.
10. Izuishi, K., A. Tsung, G. Jeyabalan, N. D. Critchlow, J. Li, K. J. Tracey, et al. 2006. Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury. J. Immunol. 176:7154-7158.
11. Kobara, M., K. Noda, M. Kitamura, A. Okamoto, T. Shiraishi, H. Toba, et al. 2010. Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice. Cardiovasc. Res. 87:424-430.
12. Lepper, C., T. A. Partridge, and C.-M. Fan. 2011. An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development 138:3639-3646.
13. Levy, R. M., K. P. Mollen, J. M. Prince, D. J. Kaczorowski, R. Vallabhaneni, S. Liu, et al. 2007. Systemic inflammation and remote organ injury following trauma require HMGB1. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293:R1538-R1544.
14. Li, Y., M. Xiang, Y. Yuan, G. Xiao, J. Zhang, Y. Jiang, et al. 2009. Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297:R1670-R1680.
15. Lotze, M. T., and K. J. Tracey. 2005. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5:331-342.
16. Marston, W. A., S. W. Davies, B. Armstrong, M. A. Farber, R. C. Mendes, J. J. Fulton, et al. 2006. Natural history of limbs with arterial insufficiency and chronic ulceration treated without revascularization. J. Vasc. Surg. 44:108-114.
17. Masaki, I., Y. Yonemitsu, A. Yamashita, S. Sata, M. Tanii, K. Komori, et al. 2002. Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2. Circ. Res. 90:966-973.
18. McKay, B. R., M. De Lisio, A. P. W. Johnston, C. E. O’Reilly, S. M. Phillips, M. A. Tarnopolsky, et al. 2009. Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans. PLoS ONE 4:e6027.
19. Messina, L. M., L. S. Brevetti, D. S. Chang, R. Paek, and R. Sarkar. 2002. Therapeutic angiogenesis for critical limb ischemia: invited commentary. J. Cont. Rel. 78:285-294.
20. Mitchell, P. O., and G. K. Pavlath. 2001. A muscle precursor cell-dependent pathway contributes to muscle growth after atrophy. Am. J. Physiol.-Cell Physiol. 281:C1706-C1715.
21. Mitchell, J. A., M. J. Paul-Clark, G. W. Clarke, S. K. McMaster, and N. Cartwright. 2007. Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease. J. Endocrinol. 193:323-330.
22. Mitola, S., M. Belleri, C. Urbinati, D. Coltrini, B. Sparatore, M. Pedrazzi, et al. 2006. Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine. J. Immunol. 176:12-15.
23. Mollen, K. P., R. M. Levy, J. M. Prince, R. A. Hoffman, M. J. Scott, D. J. Kaczorowski, et al. 2008. Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells. J. Leukoc. Biol. 83:80-88.
24. Nelson, M. T., D. Y. Greenblatt, G. Soma, V. Rajimanickam, C. C. Greenberg, and K. C. Kent. 2012. Preoperative factors predict mortality after major lower-extremity amputation. Surgery 152, 685-696.
25. Palumbo, R., M. Sampaolesi, F. De Marchis, R. Tonlorenzi, S. Colombetti, A. Mondino, et al. 2004. Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J. Cell Biol. 164:441-449.
26. Powell, R. J., J. Dormandy, M. Simons, R. Morishita, and B. H. Annex. 2004. Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial. Vasc. Med. 9:193-198.
27. Rajagopalan, S., E. R. Mohler, R. J. Lederman, F. O. Mendelsohn, J. F. Saucedo, C. K. Goldman, et al. 2003. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 108:1933-1938.
28. Rando, T. A., and H. M. Blau. 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125:1275-1287.
29. Relaix, F., and P. S. Zammit. 2012. Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage. Development 139:2845-2856.
30. Sachdev, U., X. Cui, and E. Tzeng. 2013. HMGB1 and TLR4 mediate skeletal muscle recovery in a murine model of hindlimb ischemia. J. Vasc. Surg. 58:460-469.
31. Sachdev, U., X. Cui, R. McEnaney, T. Wang, K. Benabou, and E. Tzeng. 2012. TLR2 and TLR4 mediate differential responses to limb ischemia through MyD88-dependent and independent pathways. PLoS ONE 7: e50654.
32. Schneider, C. A., W. S. Rasband, and K. W. Eliceiri. 2012. NIH Image to ImageJ: 25 years of image analysis. Nat. Meth. 9:671-675.
33. Selvin, E., and T. P. Erlinger. 2004. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation 110:738-743.
34. Serrano, A. L., and P. Muñoz-Cánoves. 2010. Regulation and dysregulation of fibrosis in skeletal muscle. Exp. Cell Res. 316:3050-3058.
35. Serrano, A. L., B. Baeza-Raja, E. Perdiguero, M. Jardã, and P. Muã±oz-Cã¡noves. 2008. Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab. 7:33-44.
36. Shireman, P. K., and M. P. Quinones. 2005. Differential necrosis despite similar perfusion in mouse strains after ischemia. J. Surg. Res. 129:242-250.
37. Steensberg, A., C. Keller, R. L. Starkie, T. Osada, M. A. Febbraio, and B. K. Pedersen. 2002. IL-6 and TNF-Î ± expression in, and release from, contracting human skeletal muscle. Am. J. Physiol.-Endocrinol. Metab. 283:E1272-E1278.
38. Tsung, A., R. Sahai, H. Tanaka, A. Nakao, M. P. Fink, M. T. Lotze, et al. 2005. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J. Exp. Med. 201: 1135-1143.
39. Vaquero, J., J. S. Campbell, J. Haque, R. S. McMahan, K. J. Riehle, R. L. Bauer, et al. 2011. Toll-like receptor 4 and myeloid differentiation factor 88 provide mechanistic insights into the cause and effects of interleukin-6 activation in mouse liver regeneration. Hepatology 54, 597-608