메뉴 건너뛰기




Volumn 139, Issue 1, 2017, Pages 189-201.e4

Epicutaneous immunotherapy induces gastrointestinal LAP+ regulatory T cells and prevents food-induced anaphylaxis

Author keywords

Epicutaneous immunotherapy; food allergy; mast cells; oral immunotherapy; regulatory T cells

Indexed keywords

ADJUVANT; ANTIGEN; FOOD ALLERGEN; LATENCY ASSOCIATED PEPTIDE; OVALBUMIN; PEANUT EXTRACT; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; ALLERGEN; CHOLERA TOXIN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IMMUNOGLOBULIN G; PEPTIDE;

EID: 85002567316     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.03.057     Document Type: Article
Times cited : (122)

References (61)
  • 1
    • 79952307149 scopus 로고    scopus 로고
    • Epidemiology of food allergy
    • 1 Sicherer, S.H., Epidemiology of food allergy. J Allergy Clin Immunol 127 (2011), 594–602.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 594-602
    • Sicherer, S.H.1
  • 2
    • 84863518133 scopus 로고    scopus 로고
    • Allergic reactions to foods in preschool-aged children in a prospective observational food allergy study
    • 2 Fleischer, D.M., Perry, T.T., Atkins, D., Wood, R.A., Burks, A.W., Jones, S.M., et al. Allergic reactions to foods in preschool-aged children in a prospective observational food allergy study. Pediatrics 130 (2012), e25–e32.
    • (2012) Pediatrics , vol.130 , pp. e25-e32
    • Fleischer, D.M.1    Perry, T.T.2    Atkins, D.3    Wood, R.A.4    Burks, A.W.5    Jones, S.M.6
  • 3
    • 0030915039 scopus 로고    scopus 로고
    • Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract
    • 3 Nelson, H.S., Lahr, J., Rule, R., Bock, A., Leung, D., Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract. J Allergy Clin Immunol 99 (1997), 744–751.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 744-751
    • Nelson, H.S.1    Lahr, J.2    Rule, R.3    Bock, A.4    Leung, D.5
  • 5
    • 79952302102 scopus 로고    scopus 로고
    • A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response
    • 5 Varshney, P., Jones, S.M., Scurlock, A.M., Perry, T.T., Kemper, A., Steele, P., et al. A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response. J Allergy Clin Immunol 127 (2011), 654–660.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 654-660
    • Varshney, P.1    Jones, S.M.2    Scurlock, A.M.3    Perry, T.T.4    Kemper, A.5    Steele, P.6
  • 7
    • 84893405498 scopus 로고    scopus 로고
    • Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3)
    • 7 Syed, A., Garcia, M.A., Lyu, S.C., Bucayu, R., Kohli, A., Ishida, S., et al. Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3). J Allergy Clin Immunol 133 (2014), 500–510.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 500-510
    • Syed, A.1    Garcia, M.A.2    Lyu, S.C.3    Bucayu, R.4    Kohli, A.5    Ishida, S.6
  • 11
    • 0030035509 scopus 로고    scopus 로고
    • Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients
    • 11 Fukaura, H., Kent, S.C., Pietrusewicz, M.J., Khoury, S.J., Weiner, H.L., Hafler, D.A., Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest 98 (1996), 70–77.
    • (1996) J Clin Invest , vol.98 , pp. 70-77
    • Fukaura, H.1    Kent, S.C.2    Pietrusewicz, M.J.3    Khoury, S.J.4    Weiner, H.L.5    Hafler, D.A.6
  • 13
    • 17444437590 scopus 로고    scopus 로고
    • Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabete Insuline Orale Group
    • 13 Chaillous, L., Lefevre, H., Thivolet, C., Boitard, C., Lahlou, N., Atlan-Gepner, C., et al. Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabete Insuline Orale Group. Lancet 356 (2000), 545–549.
    • (2000) Lancet , vol.356 , pp. 545-549
    • Chaillous, L.1    Lefevre, H.2    Thivolet, C.3    Boitard, C.4    Lahlou, N.5    Atlan-Gepner, C.6
  • 14
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance
    • 14 Neurath, M.F., Fuss, I., Kelsall, B.L., Presky, D.H., Waegell, W., Strober, W., Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance. J Exp Med 183 (1996), 2605–2616.
    • (1996) J Exp Med , vol.183 , pp. 2605-2616
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 15
    • 84861682890 scopus 로고    scopus 로고
    • Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa
    • 15 Leonard, S.A., Martos, G., Wang, W., Nowak-Wegrzyn, A., Berin, M.C., Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa. J Allergy Clin Immunol 129 (2012), 1579–1587.e1.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 1579-1587.e1
    • Leonard, S.A.1    Martos, G.2    Wang, W.3    Nowak-Wegrzyn, A.4    Berin, M.C.5
  • 16
    • 84904428409 scopus 로고    scopus 로고
    • Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells
    • 16 Burton, O.T., Noval Rivas, M., Zhou, J.S., Logsdon, S.L., Darling, A.R., Koleoglou, K.J., et al. Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells. Immunity, 41, 2014, 14151.
    • (2014) Immunity , vol.41 , pp. 14151
    • Burton, O.T.1    Noval Rivas, M.2    Zhou, J.S.3    Logsdon, S.L.4    Darling, A.R.5    Koleoglou, K.J.6
  • 17
    • 77949360619 scopus 로고    scopus 로고
    • Epicutaneous immunotherapy on intact skin using a new delivery system in a murine model of allergy
    • 17 Mondoulet, L., Dioszeghy, V., Ligouis, M., Dhelft, V., Dupont, C., Benhamou, P.H., Epicutaneous immunotherapy on intact skin using a new delivery system in a murine model of allergy. Clin Exp Allergy 40 (2010), 659–667.
    • (2010) Clin Exp Allergy , vol.40 , pp. 659-667
    • Mondoulet, L.1    Dioszeghy, V.2    Ligouis, M.3    Dhelft, V.4    Dupont, C.5    Benhamou, P.H.6
  • 19
    • 84857406571 scopus 로고    scopus 로고
    • Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice
    • 19 Mondoulet, L., Dioszeghy, V., Larcher, T., Ligouis, M., Dhelft, V., Puteaux, E., et al. Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice. PLoS One, 7, 2012, e31967.
    • (2012) PLoS One , vol.7 , pp. e31967
    • Mondoulet, L.1    Dioszeghy, V.2    Larcher, T.3    Ligouis, M.4    Dhelft, V.5    Puteaux, E.6
  • 20
    • 79956201500 scopus 로고    scopus 로고
    • Epicutaneous immunotherapy results in rapid allergen uptake by dendritic cells through intact skin and downregulates the allergen-specific response in sensitized mice
    • 20 Dioszeghy, V., Mondoulet, L., Dhelft, V., Ligouis, M., Puteaux, E., Benhamou, P.H., et al. Epicutaneous immunotherapy results in rapid allergen uptake by dendritic cells through intact skin and downregulates the allergen-specific response in sensitized mice. J Immunol 186 (2011), 5629–5637.
    • (2011) J Immunol , vol.186 , pp. 5629-5637
    • Dioszeghy, V.1    Mondoulet, L.2    Dhelft, V.3    Ligouis, M.4    Puteaux, E.5    Benhamou, P.H.6
  • 21
    • 84901234714 scopus 로고    scopus 로고
    • The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice
    • 21 Dioszeghy, V., Mondoulet, L., Dhelft, V., Ligouis, M., Puteaux, E., Dupont, C., et al. The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice. Clin Exp Allergy 44 (2014), 867–881.
    • (2014) Clin Exp Allergy , vol.44 , pp. 867-881
    • Dioszeghy, V.1    Mondoulet, L.2    Dhelft, V.3    Ligouis, M.4    Puteaux, E.5    Dupont, C.6
  • 22
    • 0037372241 scopus 로고    scopus 로고
    • CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking
    • 22 Soler, D., Humphreys, T.L., Spinola, S.M., Campbell, J.J., CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. Blood 101 (2003), 1677–1682.
    • (2003) Blood , vol.101 , pp. 1677-1682
    • Soler, D.1    Humphreys, T.L.2    Spinola, S.M.3    Campbell, J.J.4
  • 24
    • 0033231492 scopus 로고    scopus 로고
    • Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
    • 24 Zabel, B.A., Agace, W.W., Campbell, J.J., Heath, H.M., Parent, D., Roberts, A.I., et al. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 190 (1999), 1241–1256.
    • (1999) J Exp Med , vol.190 , pp. 1241-1256
    • Zabel, B.A.1    Agace, W.W.2    Campbell, J.J.3    Heath, H.M.4    Parent, D.5    Roberts, A.I.6
  • 25
    • 0027237424 scopus 로고
    • Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
    • 25 Berlin, C., Berg, E.L., Briskin, M.J., Andrew, D.P., Kilshaw, P.J., Holzmann, B., et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 74 (1993), 185–195.
    • (1993) Cell , vol.74 , pp. 185-195
    • Berlin, C.1    Berg, E.L.2    Briskin, M.J.3    Andrew, D.P.4    Kilshaw, P.J.5    Holzmann, B.6
  • 26
    • 84859808080 scopus 로고    scopus 로고
    • Oral tolerance to food protein
    • 26 Pabst, O., Mowat, A.M., Oral tolerance to food protein. Mucosal Immunol 5 (2012), 232–239.
    • (2012) Mucosal Immunol , vol.5 , pp. 232-239
    • Pabst, O.1    Mowat, A.M.2
  • 27
    • 78650902704 scopus 로고    scopus 로고
    • Mechanisms of allergen-specific immunotherapy
    • quiz 8-9
    • 27 Akdis, C.A., Akdis, M., Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol 127 (2011), 18–27 quiz 8-9.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 18-27
    • Akdis, C.A.1    Akdis, M.2
  • 28
    • 84871834613 scopus 로고    scopus 로고
    • Can we produce true tolerance in patients with food allergy?
    • 28 Berin, M.C., Mayer, L., Can we produce true tolerance in patients with food allergy?. J Allergy Clin Immunol 131 (2013), 14–22.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 14-22
    • Berin, M.C.1    Mayer, L.2
  • 29
    • 6344275820 scopus 로고    scopus 로고
    • IgE-mediated mast cell activation induces Langerhans cell migration in vivo
    • 29 Jawdat, D.M., Albert, E.J., Rowden, G., Haidl, I.D., Marshall, J.S., IgE-mediated mast cell activation induces Langerhans cell migration in vivo. J Immunol 173 (2004), 5275–5282.
    • (2004) J Immunol , vol.173 , pp. 5275-5282
    • Jawdat, D.M.1    Albert, E.J.2    Rowden, G.3    Haidl, I.D.4    Marshall, J.S.5
  • 31
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
    • 31 Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D.A., Weiner, H.L., Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265 (1994), 1237–1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 32
    • 47249119632 scopus 로고    scopus 로고
    • Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis
    • 32 Chen, M.L., Yan, B.S., Bando, Y., Kuchroo, V.K., Weiner, H.L., Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis. J Immunol 180 (2008), 7327–7337.
    • (2008) J Immunol , vol.180 , pp. 7327-7337
    • Chen, M.L.1    Yan, B.S.2    Bando, Y.3    Kuchroo, V.K.4    Weiner, H.L.5
  • 33
    • 34547563816 scopus 로고    scopus 로고
    • Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody
    • 33 Ishikawa, H., Ochi, H., Chen, M.L., Frenkel, D., Maron, R., Weiner, H.L., Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody. Diabetes 56 (2007), 2103–2109.
    • (2007) Diabetes , vol.56 , pp. 2103-2109
    • Ishikawa, H.1    Ochi, H.2    Chen, M.L.3    Frenkel, D.4    Maron, R.5    Weiner, H.L.6
  • 34
    • 33744990181 scopus 로고    scopus 로고
    • Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25− LAP+ T cells
    • 34 Ochi, H., Abraham, M., Ishikawa, H., Frenkel, D., Yang, K., Basso, A.S., et al. Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25− LAP+ T cells. Nat Med 12 (2006), 627–635.
    • (2006) Nat Med , vol.12 , pp. 627-635
    • Ochi, H.1    Abraham, M.2    Ishikawa, H.3    Frenkel, D.4    Yang, K.5    Basso, A.S.6
  • 35
    • 0037371301 scopus 로고    scopus 로고
    • CD4+CD25− T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism
    • 35 Oida, T., Zhang, X., Goto, M., Hachimura, S., Totsuka, M., Kaminogawa, S., et al. CD4+CD25− T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism. J Immunol 170 (2003), 2516–2522.
    • (2003) J Immunol , vol.170 , pp. 2516-2522
    • Oida, T.1    Zhang, X.2    Goto, M.3    Hachimura, S.4    Totsuka, M.5    Kaminogawa, S.6
  • 36
    • 58749093614 scopus 로고    scopus 로고
    • Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25− LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells
    • 36 Wu, H.Y., Quintana, F.J., Weiner, H.L., Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25− LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells. J Immunol 181 (2008), 6038–6050.
    • (2008) J Immunol , vol.181 , pp. 6038-6050
    • Wu, H.Y.1    Quintana, F.J.2    Weiner, H.L.3
  • 37
    • 83755173097 scopus 로고    scopus 로고
    • Inducible CD4+LAP+Foxp3− regulatory T cells suppress allergic inflammation
    • 37 Duan, W., So, T., Mehta, A.K., Choi, H., Croft, M., Inducible CD4+LAP+Foxp3− regulatory T cells suppress allergic inflammation. J Immunol 187 (2011), 6499–6507.
    • (2011) J Immunol , vol.187 , pp. 6499-6507
    • Duan, W.1    So, T.2    Mehta, A.K.3    Choi, H.4    Croft, M.5
  • 38
    • 77953116038 scopus 로고    scopus 로고
    • Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset
    • 38 Gandhi, R., Farez, M.F., Wang, Y., Kozoriz, D., Quintana, F.J., Weiner, H.L., Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset. J Immunol 184 (2010), 4620–4624.
    • (2010) J Immunol , vol.184 , pp. 4620-4624
    • Gandhi, R.1    Farez, M.F.2    Wang, Y.3    Kozoriz, D.4    Quintana, F.J.5    Weiner, H.L.6
  • 39
    • 84866916324 scopus 로고    scopus 로고
    • LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer
    • 39 Mahalingam, J., Lin, Y.C., Chiang, J.M., Su, P.J., Fang, J.H., Chu, Y.Y., et al. LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer. Clin Cancer Res 18 (2012), 5224–5233.
    • (2012) Clin Cancer Res , vol.18 , pp. 5224-5233
    • Mahalingam, J.1    Lin, Y.C.2    Chiang, J.M.3    Su, P.J.4    Fang, J.H.5    Chu, Y.Y.6
  • 40
    • 84895168217 scopus 로고    scopus 로고
    • Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(−) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells
    • 40 Scurr, M., Ladell, K., Besneux, M., Christian, A., Hockey, T., Smart, K., et al. Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(−) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells. Mucosal Immunol 7 (2014), 428–439.
    • (2014) Mucosal Immunol , vol.7 , pp. 428-439
    • Scurr, M.1    Ladell, K.2    Besneux, M.3    Christian, A.4    Hockey, T.5    Smart, K.6
  • 41
    • 0042831022 scopus 로고    scopus 로고
    • Reduced transforming growth factor-beta1-producing T cells in the duodenal mucosa of children with food allergy
    • 41 Perez-Machado, M.A., Ashwood, P., Thomson, M.A., Latcham, F., Sim, R., Walker-Smith, J.A., et al. Reduced transforming growth factor-beta1-producing T cells in the duodenal mucosa of children with food allergy. Eur J Immunol 33 (2003), 2307–2315.
    • (2003) Eur J Immunol , vol.33 , pp. 2307-2315
    • Perez-Machado, M.A.1    Ashwood, P.2    Thomson, M.A.3    Latcham, F.4    Sim, R.5    Walker-Smith, J.A.6
  • 42
    • 0036227794 scopus 로고    scopus 로고
    • Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile
    • 42 Beyer, K., Castro, R., Birnbaum, A., Benkov, K., Pittman, N., Sampson, H.A., Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile. J Allergy Clin Immunol 109 (2002), 707–713.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 707-713
    • Beyer, K.1    Castro, R.2    Birnbaum, A.3    Benkov, K.4    Pittman, N.5    Sampson, H.A.6
  • 43
    • 59849119691 scopus 로고    scopus 로고
    • CD69+ CD4+ CD25− T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1
    • 43 Han, Y., Guo, Q., Zhang, M., Chen, Z., Cao, X., CD69+ CD4+ CD25− T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J Immunol 182 (2009), 111–120.
    • (2009) J Immunol , vol.182 , pp. 111-120
    • Han, Y.1    Guo, Q.2    Zhang, M.3    Chen, Z.4    Cao, X.5
  • 44
    • 84873193482 scopus 로고    scopus 로고
    • Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3− CD4+ CD25− T cells modulates TLR-4 induced TNF-alpha production
    • 44 Boswell, S., Pathan, A.A., Pereira, S.P., Williams, R., Behboudi, S., Induction of CD152 (CTLA-4) and LAP (TGF-beta1) in human Foxp3− CD4+ CD25− T cells modulates TLR-4 induced TNF-alpha production. Immunobiology 218 (2013), 427–434.
    • (2013) Immunobiology , vol.218 , pp. 427-434
    • Boswell, S.1    Pathan, A.A.2    Pereira, S.P.3    Williams, R.4    Behboudi, S.5
  • 45
    • 0037108485 scopus 로고    scopus 로고
    • Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25− precursors
    • 45 Zheng, S.G., Gray, J.D., Ohtsuka, K., Yamagiwa, S., Horwitz, D.A., Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25− precursors. J Immunol 169 (2002), 4183–4189.
    • (2002) J Immunol , vol.169 , pp. 4183-4189
    • Zheng, S.G.1    Gray, J.D.2    Ohtsuka, K.3    Yamagiwa, S.4    Horwitz, D.A.5
  • 46
    • 0038264036 scopus 로고    scopus 로고
    • Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
    • 46 Mora, J.R., Bono, M.R., Manjunath, N., Weninger, W., Cavanagh, L.L., Rosemblatt, M., et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424 (2003), 88–93.
    • (2003) Nature , vol.424 , pp. 88-93
    • Mora, J.R.1    Bono, M.R.2    Manjunath, N.3    Weninger, W.4    Cavanagh, L.L.5    Rosemblatt, M.6
  • 47
    • 0036099957 scopus 로고    scopus 로고
    • Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin
    • 47 Stagg, A.J., Kamm, M.A., Knight, S.C., Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur J Immunol 32 (2002), 1445–1454.
    • (2002) Eur J Immunol , vol.32 , pp. 1445-1454
    • Stagg, A.J.1    Kamm, M.A.2    Knight, S.C.3
  • 48
    • 0037033376 scopus 로고    scopus 로고
    • Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues
    • 48 Campbell, D.J., Butcher, E.C., Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 195 (2002), 135–141.
    • (2002) J Exp Med , vol.195 , pp. 135-141
    • Campbell, D.J.1    Butcher, E.C.2
  • 49
    • 1542644156 scopus 로고    scopus 로고
    • Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets
    • 49 Dudda, J.C., Simon, J.C., Martin, S., Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets. J Immunol 172 (2004), 857–863.
    • (2004) J Immunol , vol.172 , pp. 857-863
    • Dudda, J.C.1    Simon, J.C.2    Martin, S.3
  • 50
    • 79955787107 scopus 로고    scopus 로고
    • Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice
    • 50 Ciabattini, A., Pettini, E., Fiorino, F., Prota, G., Pozzi, G., Medaglini, D., Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice. PLoS One, 6, 2011, e19346.
    • (2011) PLoS One , vol.6 , pp. e19346
    • Ciabattini, A.1    Pettini, E.2    Fiorino, F.3    Prota, G.4    Pozzi, G.5    Medaglini, D.6
  • 51
    • 84884239043 scopus 로고    scopus 로고
    • Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract
    • 51 Ruane, D., Brane, L., Reis, B.S., Cheong, C., Poles, J., Do, Y., et al. Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. J Exp Med 210 (2013), 1871–1888.
    • (2013) J Exp Med , vol.210 , pp. 1871-1888
    • Ruane, D.1    Brane, L.2    Reis, B.S.3    Cheong, C.4    Poles, J.5    Do, Y.6
  • 52
    • 42149162890 scopus 로고    scopus 로고
    • Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling
    • 52 Kashyap, M., Thornton, A.M., Norton, S.K., Barnstein, B., Macey, M., Brenzovich, J., et al. Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling. J Immunol 180 (2008), 2039–2043.
    • (2008) J Immunol , vol.180 , pp. 2039-2043
    • Kashyap, M.1    Thornton, A.M.2    Norton, S.K.3    Barnstein, B.4    Macey, M.5    Brenzovich, J.6
  • 53
    • 84856002777 scopus 로고    scopus 로고
    • Regulatory T cells enhance mast cell production of IL-6 via surface-bound TGF-beta
    • 53 Ganeshan, K., Bryce, P.J., Regulatory T cells enhance mast cell production of IL-6 via surface-bound TGF-beta. J Immunol 188 (2012), 594–603.
    • (2012) J Immunol , vol.188 , pp. 594-603
    • Ganeshan, K.1    Bryce, P.J.2
  • 54
    • 55349084351 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction
    • 54 Gri, G., Piconese, S., Frossi, B., Manfroi, V., Merluzzi, S., Tripodo, C., et al. CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction. Immunity 29 (2008), 771–781.
    • (2008) Immunity , vol.29 , pp. 771-781
    • Gri, G.1    Piconese, S.2    Frossi, B.3    Manfroi, V.4    Merluzzi, S.5    Tripodo, C.6
  • 56
    • 58149191873 scopus 로고    scopus 로고
    • TGF-beta1 attenuates mediator release and de novo Kit expression by human skin mast cells through a Smad-dependent pathway
    • 56 Zhao, W., Gomez, G., Yu, S.H., Ryan, J.J., Schwartz, L.B., TGF-beta1 attenuates mediator release and de novo Kit expression by human skin mast cells through a Smad-dependent pathway. J Immunol 181 (2008), 7263–7272.
    • (2008) J Immunol , vol.181 , pp. 7263-7272
    • Zhao, W.1    Gomez, G.2    Yu, S.H.3    Ryan, J.J.4    Schwartz, L.B.5
  • 57
    • 33845915104 scopus 로고    scopus 로고
    • Th3 cells in peripheral tolerance, I: induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice
    • 57 Carrier, Y., Yuan, J., Kuchroo, V.K., Weiner, H.L., Th3 cells in peripheral tolerance, I: induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice. J Immunol 178 (2007), 179–185.
    • (2007) J Immunol , vol.178 , pp. 179-185
    • Carrier, Y.1    Yuan, J.2    Kuchroo, V.K.3    Weiner, H.L.4
  • 58
    • 77957352514 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance
    • Blazquez, A.B., Mayer, L., Berin, M.C., Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance. Gastroenterology 139 (2010), 1301–1309.
    • (2010) Gastroenterology , vol.139 , pp. 1301-1309
    • Blazquez, A.B.1    Mayer, L.2    Berin, M.C.3
  • 59
    • 84861682890 scopus 로고    scopus 로고
    • Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa
    • Leonard, S.A., Martos, G., Wang, W., Nowak-Wegrzyn, A., Berin, M.C., Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa. J Allergy Clin Immunol 129 (2012), 1579–1587.e1.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 1579-1587.e1
    • Leonard, S.A.1    Martos, G.2    Wang, W.3    Nowak-Wegrzyn, A.4    Berin, M.C.5
  • 60
    • 33947612179 scopus 로고    scopus 로고
    • FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells
    • Ekoff, M., Strasser, A., Nilsson, G., FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells. J Immunol 178 (2007), 4177–4183.
    • (2007) J Immunol , vol.178 , pp. 4177-4183
    • Ekoff, M.1    Strasser, A.2    Nilsson, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.