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Volumn 2, Issue 7, 2014, Pages

Lack of megalin expression in adult human terminal ileum suggests Megalin-Independent Cubilin/Amnionless activity during vitamin B12 absorption

Author keywords

Amnionless; Cubilin; Human terminal ileum; Megalin; Vitamin B12 absorption

Indexed keywords

COMPLEMENTARY DNA; CUBILIN; CYANOCOBALAMIN; MEGALIN; MESSENGER RNA;

EID: 85002558361     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12086     Document Type: Article
Times cited : (21)

References (39)
  • 1
    • 0029101674 scopus 로고
    • Selective intestinal malabsorption of vitamin B12 displays recessive mendelian inheritance: Assignment of a locus to chromosome 10 by linkage
    • Aminoff, M., E. Tahvanainen, R. Grasbeck, J. Weissenbach, H. Broch, and C. A. de la Chapelle. 1995. Selective intestinal malabsorption of vitamin B12 displays recessive mendelian inheritance: assignment of a locus to chromosome 10 by linkage. Am. J. Hum. Genet. 57:824-831.
    • (1995) Am. J. Hum. Genet , vol.57 , pp. 824-831
    • Aminoff, M.1    Tahvanainen, E.2    Grasbeck, R.3    Weissenbach, J.4    Broch, H.5    De La Chapelle, C.A.6
  • 2
    • 0033051889 scopus 로고    scopus 로고
    • Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1. Nat
    • Aminoff, M., J. E. Carter, R. B. Chadwick, C. Johnson, R. Grasbeck, M. A. Abdelaal, et al. 1999. Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1. Nat. Genet. 21:309-313.
    • (1999) Genet , vol.21 , pp. 309-313
    • Aminoff, M.1    Carter, J.E.2    Chadwick, R.B.3    Johnson, C.4    Grasbeck, R.5    Abdelaal, M.A.6
  • 3
    • 77949674869 scopus 로고    scopus 로고
    • Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes
    • Andersen, C. B., M. Madsen, T. Storm, S. K. Moestrup, and G. R. Andersen. 2010. Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes. Nature 464:445-448.
    • (2010) Nature , vol.464 , pp. 445-448
    • Andersen, C.B.1    Madsen, M.2    Storm, T.3    Moestrup, S.K.4    Andersen, G.R.5
  • 4
    • 77949904065 scopus 로고    scopus 로고
    • Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin
    • Beedholm-Ebsen, R., K. van de Wetering, T. Hardlei, E. Nexo, P. Borst, and S. K. Moestrup. 2010. Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin. Blood 115:1632-1639.
    • (2010) Blood , vol.115 , pp. 1632-1639
    • Beedholm-Ebsen, R.1    Van De Wetering, K.2    Hardlei, T.3    Nexo, E.4    Borst, P.5    Moestrup, S.K.6
  • 5
    • 0031576218 scopus 로고    scopus 로고
    • Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein
    • Birn, H., P. J. Verroust, E. Nexo, H. Hager, C. Jacobsen, E. I. Christensen, et al. 1997. Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein. J. Biol. Chem. 272:26497-26504.
    • (1997) J. Biol. Chem , vol.272 , pp. 26497-26504
    • Birn, H.1    Verroust, P.J.2    Nexo, E.3    Hager, H.4    Jacobsen, C.5    Christensen, E.I.6
  • 6
    • 0034073250 scopus 로고    scopus 로고
    • Cubilin is an albumin binding protein important for renal tubular albumin reabsorption
    • Birn, H., J. C. Fyfe, C. Jacobsen, F. Mounier, P. J. Verroust, H. Orskov, et al. 2000. Cubilin is an albumin binding protein important for renal tubular albumin reabsorption. J. Clin. Invest. 105:1353-1361.
    • (2000) J. Clin. Invest , vol.105 , pp. 1353-1361
    • Birn, H.1    Fyfe, J.C.2    Jacobsen, C.3    Mounier, F.4    Verroust, P.J.5    Orskov, H.6
  • 7
    • 0024382762 scopus 로고
    • Development of luminal protein digestion: Implications for biologically active dietary polypeptides
    • Britton, J. R., and O. Koldovsky. 1989. Development of luminal protein digestion: implications for biologically active dietary polypeptides. J. Pediatr. Gastroenterol. Nutr. 9:144-162.
    • (1989) J. Pediatr. Gastroenterol. Nutr , vol.9 , pp. 144-162
    • Britton, J.R.1    Koldovsky, O.2
  • 8
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • Bustin, S. A., V. Benes, J. A. Garson, J. Hellemans, J. Huggett, M. Kubista, et al. 2009. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 55:611-622.
    • (2009) Clin. Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5    Kubista, M.6
  • 9
    • 84878718577 scopus 로고    scopus 로고
    • Short-term gestation, long-term risk: Prematurity and chronic kidney disease
    • Carmody, J. B., and J. R. Charlton. 2013. Short-term gestation, long-term risk: prematurity and chronic kidney disease. Pediatrics 131:1168-1179.
    • (2013) Pediatrics , vol.131 , pp. 1168-1179
    • Carmody, J.B.1    Charlton, J.R.2
  • 10
    • 84878769871 scopus 로고    scopus 로고
    • Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head
    • Cases, O., A. Perea-Gomez, D. P. Aguiar, A. Nykjaer, S. Amsellem, J. Chandellier, et al. 2013. Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. J. Biol. Chem. 288:16655-16670.
    • (2013) J. Biol. Chem , vol.288 , pp. 16655-16670
    • Cases, O.1    Perea-Gomez, A.2    Aguiar, D.P.3    Nykjaer, A.4    Amsellem, S.5    Chandellier, J.6
  • 12
    • 84874527043 scopus 로고    scopus 로고
    • From bowel to kidneys: The role of cubilin in physiology and disease
    • Christensen, E. I., R. Nielsen, and H. Birn. 2013. From bowel to kidneys: the role of cubilin in physiology and disease. Nephrol. Dial. Transplant. 28:274-281.
    • (2013) Nephrol. Dial. Transplant , vol.28 , pp. 274-281
    • Christensen, E.I.1    Nielsen, R.2    Birn, H.3
  • 13
    • 28444465484 scopus 로고    scopus 로고
    • Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex
    • Coudroy, G., J. Gburek, R. Kozyraki, M. Madsen, G. Trugnan, S. K. Moestrup, et al. 2005. Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex. J. Am. Soc. Nephrol. 16:2330-2337.
    • (2005) J. Am. Soc. Nephrol , vol.16 , pp. 2330-2337
    • Coudroy, G.1    Gburek, J.2    Kozyraki, R.3    Madsen, M.4    Trugnan, G.5    Moestrup, S.K.6
  • 14
    • 1442357042 scopus 로고    scopus 로고
    • The functional cobalamin (Vitamin B-12)-intrinsic factor receptor is a novel complex of cubilin and amnionless
    • Fyfe, J. C., M. Madsen, P. Hojrup, E. I. Christensen, S. M. Tanner, A. de la Chapelle, et al. 2004. The functional cobalamin (vitamin B-12)-intrinsic factor receptor is a novel complex of cubilin and amnionless. Blood 103:1573-1579.
    • (2004) Blood , vol.103 , pp. 1573-1579
    • Fyfe, J.C.1    Madsen, M.2    Hojrup, P.3    Christensen, E.I.4    Tanner, S.M.5    De La Chapelle, A.6
  • 15
    • 85003027478 scopus 로고    scopus 로고
    • The anatomy and physiology of the small bowel
    • J. W. L. Fielding, and M. H. Hallissey, eds., Springer, London
    • Gourevitch, D. 2005. The anatomy and physiology of the small bowel. Pp. 39-44 in J. W. L. Fielding, and M. H. Hallissey, eds. Upper gastrointestinal surgery. Springer, London.
    • (2005) Upper Gastrointestinal Surgery , pp. 39-44
    • Gourevitch, D.1
  • 16
    • 23744450398 scopus 로고    scopus 로고
    • Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (Vitamin B-12) absorption in vivo
    • He, Q. C., M. Madsen, A. Kilkenney, B. Gregory, E. I. Christensen, H. Vorum, et al. 2005. Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B-12) absorption in vivo. Blood 106:1447-1453.
    • (2005) Blood , vol.106 , pp. 1447-1453
    • He, Q.C.1    Madsen, M.2    Kilkenney, A.3    Gregory, B.4    Christensen, E.I.5    Vorum, H.6
  • 17
    • 0035065591 scopus 로고    scopus 로고
    • The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain
    • Kalantry, S., S. Manning, O. Haub, C. Tomihara-Newberger, H. G. Lee, J. Fangman, et al. 2001. The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain. Nat. Genet. 27:412-416.
    • (2001) Nat. Genet , vol.27 , pp. 412-416
    • Kalantry, S.1    Manning, S.2    Haub, O.3    Tomihara-Newberger, C.4    Lee, H.G.5    Fangman, J.6
  • 18
  • 19
    • 84875868893 scopus 로고    scopus 로고
    • Vitamin B12 absorption: Mammalian physiology and acquired and inherited disorders
    • Kozyraki, R., and O. Cases. 2013. Vitamin B12 absorption: mammalian physiology and acquired and inherited disorders. Biochimie 95:1002-1007.
    • (2013) Biochimie , vol.95 , pp. 1002-1007
    • Kozyraki, R.1    Cases, O.2
  • 20
    • 0032525203 scopus 로고    scopus 로고
    • The human intrinsic factor-vitamin B12 receptor, cubilin: Molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region
    • Kozyraki, R., M. Kristiansen, A. Silahtaroglu, C. Hansen, C. Jacobsen, N. Tommerup, et al. 1998. The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region. Blood 91:3593-3600.
    • (1998) Blood , vol.91 , pp. 3593-3600
    • Kozyraki, R.1    Kristiansen, M.2    Silahtaroglu, A.3    Hansen, C.4    Jacobsen, C.5    Tommerup, N.6
  • 21
    • 0033056072 scopus 로고    scopus 로고
    • The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein
    • Kozyraki, R., J. Fyfe, M. Kristiansen, C. Gerdes, C. Jacobsen, S. Cui, et al. 1999. The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein. Nat. Med. 5:656-661.
    • (1999) Nat. Med , vol.5 , pp. 656-661
    • Kozyraki, R.1    Fyfe, J.2    Kristiansen, M.3    Gerdes, C.4    Jacobsen, C.5    Cui, S.6
  • 22
    • 0035940434 scopus 로고    scopus 로고
    • Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia
    • Kozyraki, R., J. Fyfe, P. J. Verroust, C. Jacobsen, A. Dautry-Varsat, J. Gburek, et al. 2001. Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia. Proc. Natl Acad. Sci. USA 98:12491-12496.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 12491-12496
    • Kozyraki, R.1    Fyfe, J.2    Verroust, P.J.3    Jacobsen, C.4    Dautry-Varsat, A.5    Gburek, J.6
  • 23
    • 0033575195 scopus 로고    scopus 로고
    • Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding
    • Kristiansen, M., R. Kozyraki, C. Jacobsen, E. Nexo, P. J. Verroust, and S. K. Moestrup. 1999. Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding. J. Biol. Chem. 274:20540-20544.
    • (1999) J. Biol. Chem , vol.274 , pp. 20540-20544
    • Kristiansen, M.1    Kozyraki, R.2    Jacobsen, C.3    Nexo, E.4    Verroust, P.J.5    Moestrup, S.K.6
  • 24
    • 0034661941 scopus 로고    scopus 로고
    • Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B (12) by cubilin
    • Kristiansen, M., M. Aminoff, C. Jacobsen, C. de la Chapelle, R. Krahe, P. J. Verroust, et al. 2000. Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B (12) by cubilin. Blood 96:405-409.
    • (2000) Blood , vol.96 , pp. 405-409
    • Kristiansen, M.1    Aminoff, M.2    Jacobsen, C.3    De La Chapelle, C.4    Krahe, R.5    Verroust, P.J.6
  • 25
  • 26
    • 0032570583 scopus 로고    scopus 로고
    • The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins
    • Moestrup, S. K., R. Kozyraki, M. Kristiansen, J. H. Kaysen, H. H. Rasmussen, D. Brault, et al. 1998. The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins. J. Biol. Chem. 273:5235-5242.
    • (1998) J. Biol. Chem , vol.273 , pp. 5235-5242
    • Moestrup, S.K.1    Kozyraki, R.2    Kristiansen, M.3    Kaysen, J.H.4    Rasmussen, H.H.5    Brault, D.6
  • 27
    • 77951254352 scopus 로고    scopus 로고
    • Proteinuria and events beyond the slit. Pediatr
    • Nielsen, R., and E. I. Christensen. 2010. Proteinuria and events beyond the slit. Pediatr. Nephrol. 25:813-822.
    • (2010) Nephrol , vol.25 , pp. 813-822
    • Nielsen, R.1    Christensen, E.I.2
  • 30
    • 77953152356 scopus 로고    scopus 로고
    • AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2
    • Pedersen, G. A., S. Chakraborty, A. L. Steinhauser, L. M. Traub, and M. Madsen. 2010. AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2. Traffic 11:706-720.
    • (2010) Traffic , vol.11 , pp. 706-720
    • Pedersen, G.A.1    Chakraborty, S.2    Steinhauser, A.L.3    Traub, L.M.4    Madsen, M.5
  • 31
    • 0016828540 scopus 로고
    • Fetal ingestion and metabolism of amniotic fluid protein
    • Pitkin, R. M., and W. A. Reynolds. 1975. Fetal ingestion and metabolism of amniotic fluid protein. Am. J. Obstet. Gynecol. 123:356-363.
    • (1975) Am. J. Obstet. Gynecol , vol.123 , pp. 356-363
    • Pitkin, R.M.1    Reynolds, W.A.2
  • 34
    • 0023387307 scopus 로고
    • Assessment of renal function in newborn infants. Pediatr
    • Springate, J. E., R. D. Fildes, and L. G. Feld. 1987. Assessment of renal function in newborn infants. Pediatr. Rev. 9:51-56.
    • (1987) Rev , vol.9 , pp. 51-56
    • Springate, J.E.1    Fildes, R.D.2    Feld, L.G.3
  • 35
    • 84874891861 scopus 로고    scopus 로고
    • Renal phenotypic investigations of megalin-deficient patients: Novel insights into tubular proteinuria and albumin filtration
    • Storm, T., L. Tranebjaerg, C. Frykholm, H. Birn, P. J. Verroust, T. Neveus, et al. 2013. Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration. Nephrol. Dial. Transplant. 28:585-591.
    • (2013) Nephrol. Dial. Transplant , vol.28 , pp. 585-591
    • Storm, T.1    Tranebjaerg, L.2    Frykholm, C.3    Birn, H.4    Verroust, P.J.5    Neveus, T.6
  • 36
    • 7244251718 scopus 로고    scopus 로고
    • Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules
    • Strope, S., R. Rivi, T. Metzger, K. Manova, and E. Lacy. 2004. Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules. Development 131:4787-4795.
    • (2004) Development , vol.131 , pp. 4787-4795
    • Strope, S.1    Rivi, R.2    Metzger, T.3    Manova, K.4    Lacy, E.5
  • 37
    • 0037371866 scopus 로고    scopus 로고
    • Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia
    • Tanner, S. M., M. Aminoff, F. A. Wright, S. Liyanarachchi, M. Kuronen, A. Saarinen, et al. 2003. Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia. Nat. Genet. 33:426-429.
    • (2003) Nat. Genet , vol.33 , pp. 426-429
    • Tanner, S.M.1    Aminoff, M.2    Wright, F.A.3    Liyanarachchi, S.4    Kuronen, M.5    Saarinen, A.6
  • 38
    • 0032387124 scopus 로고    scopus 로고
    • The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives
    • Tomihara-Newberger, C., O. Haub, H. G. Lee, V. Soares, K. Manova, and E. Lacy. 1998. The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives. Dev. Biol. 204:34-54.
    • (1998) Dev. Biol , vol.204 , pp. 34-54
    • Tomihara-Newberger, C.1    Haub, O.2    Lee, H.G.3    Soares, V.4    Manova, K.5    Lacy, E.6


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