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Volumn 36, Issue 12, 2016, Pages 1104-1111

Absolute first trimester cell-free DNA levels and their associations with adverse pregnancy outcomes

Author keywords

[No Author keywords available]

Indexed keywords

CELL FREE PLACENTAL DNA; DNA; PREGNANCY ASSOCIATED PLASMA PROTEIN A; UNCLASSIFIED DRUG; PAPPA1 PROTEIN, HUMAN; PLACENTAL GROWTH FACTOR;

EID: 85002412794     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.4940     Document Type: Article
Times cited : (32)

References (54)
  • 1
    • 60249094744 scopus 로고    scopus 로고
    • Pathophysiology of placentation abnormalities in pregnancy-induced hypertension
    • Furuya M, Ishida J, Aoki I, Fukamizu A. Pathophysiology of placentation abnormalities in pregnancy-induced hypertension. Vasc Health Risk Manag 2008;4:1301–13.
    • (2008) Vasc Health Risk Manag , vol.4 , pp. 1301-1313
    • Furuya, M.1    Ishida, J.2    Aoki, I.3    Fukamizu, A.4
  • 2
    • 79952310759 scopus 로고    scopus 로고
    • The “Great Obstetrical Syndromes” are associated with disorders of deep placentation
    • Brosens I, Pijnenborg R, Vercruysse L, Romero R. The “Great Obstetrical Syndromes” are associated with disorders of deep placentation. Am J Obstet Gynecol 2011;204:193–201.
    • (2011) Am J Obstet Gynecol , vol.204 , pp. 193-201
    • Brosens, I.1    Pijnenborg, R.2    Vercruysse, L.3    Romero, R.4
  • 3
    • 84921001171 scopus 로고    scopus 로고
    • A systematic review of placental pathology in maternal diabetes mellitus
    • Huynh J, Dawson D, Roberts D, Bentley-Lewis R. A systematic review of placental pathology in maternal diabetes mellitus. Placenta 2015;36:101–14.
    • (2015) Placenta , vol.36 , pp. 101-114
    • Huynh, J.1    Dawson, D.2    Roberts, D.3    Bentley-Lewis, R.4
  • 4
    • 20144367499 scopus 로고    scopus 로고
    • The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community
    • Milne F, Redman C, Walker J, et al. The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community. BMJ 2005;330:576–80.
    • (2005) BMJ , vol.330 , pp. 576-580
    • Milne, F.1    Redman, C.2    Walker, J.3
  • 5
    • 79961078416 scopus 로고    scopus 로고
    • Evaluation of 7 serum biomarkers and uterine artery Doppler ultrasound for first-trimester prediction of preeclampsia: a systematic review
    • Kuc S, Wortelboer EJ, vanRijn BB, et al. Evaluation of 7 serum biomarkers and uterine artery Doppler ultrasound for first-trimester prediction of preeclampsia: a systematic review. Obstet Gynecol Surv 2011;66:225–39.
    • (2011) Obstet Gynecol Surv , vol.66 , pp. 225-239
    • Kuc, S.1    Wortelboer, E.J.2    van Rijn, B.B.3
  • 7
    • 84899054801 scopus 로고    scopus 로고
    • Prediction of gestational diabetes early in pregnancy: targeting the long-term complications
    • Correa PJ, Vargas JF, Sen S, Illanes SE. Prediction of gestational diabetes early in pregnancy: targeting the long-term complications. Gynecol Obstet Invest 2014;77:145–9.
    • (2014) Gynecol Obstet Invest , vol.77 , pp. 145-149
    • Correa, P.J.1    Vargas, J.F.2    Sen, S.3    Illanes, S.E.4
  • 8
    • 84860538613 scopus 로고    scopus 로고
    • First trimester maternal serum PIGF, free β-hCG, PAPP-A, PP-13, uterine artery Doppler and maternal history for the prediction of preeclampsia
    • Di Lorenzo G, Ceccarello M, Cecotti V, et al. First trimester maternal serum PIGF, free β-hCG, PAPP-A, PP-13, uterine artery Doppler and maternal history for the prediction of preeclampsia. Placenta 2012;33:495–501.
    • (2012) Placenta , vol.33 , pp. 495-501
    • Di Lorenzo, G.1    Ceccarello, M.2    Cecotti, V.3
  • 9
    • 84878030404 scopus 로고    scopus 로고
    • Maternal characteristics, mean arterial pressure and serum markers in early prediction of preeclampsia
    • Kuc S, Koster MP, Franx A, et al. Maternal characteristics, mean arterial pressure and serum markers in early prediction of preeclampsia. PLoS One 2013;8:e63546.
    • (2013) PLoS One , vol.8
    • Kuc, S.1    Koster, M.P.2    Franx, A.3
  • 10
    • 84872020900 scopus 로고    scopus 로고
    • First trimester serum analytes, maternal characteristics and ultrasound markers to predict pregnancies at risk for preterm birth
    • Stout MJ, Goetzinger KR, Tuuli MG, et al. First trimester serum analytes, maternal characteristics and ultrasound markers to predict pregnancies at risk for preterm birth. Placenta 2013;34:14–9.
    • (2013) Placenta , vol.34 , pp. 14-19
    • Stout, M.J.1    Goetzinger, K.R.2    Tuuli, M.G.3
  • 11
    • 84898640686 scopus 로고    scopus 로고
    • Validation of early risk-prediction models for gestational diabetes based on clinical characteristics
    • Thériault S, Forest JC, Massé J, Giguère Y. Validation of early risk-prediction models for gestational diabetes based on clinical characteristics. Diabetes Res Clin Pract 2014;103:419–25.
    • (2014) Diabetes Res Clin Pract , vol.103 , pp. 419-425
    • Thériault, S.1    Forest, J.C.2    Massé, J.3    Giguère, Y.4
  • 12
    • 0035154948 scopus 로고    scopus 로고
    • Increased maternal plasma fetal DNA concentrations in women who eventually develop preeclampsia
    • Leung TN, Zhang J, Lau TK, Lo YM. Increased maternal plasma fetal DNA concentrations in women who eventually develop preeclampsia. Clin Chem 2001;47:137–9.
    • (2001) Clin Chem , vol.47 , pp. 137-139
    • Leung, T.N.1    Zhang, J.2    Lau, T.K.3    Lo, Y.M.4
  • 13
    • 0036241311 scopus 로고    scopus 로고
    • The levels of circulatory cell free fetal DNA in maternal plasma are elevated prior to the onset of preeclampsia
    • Zhong XY, Holzgreve W, Hahn S. The levels of circulatory cell free fetal DNA in maternal plasma are elevated prior to the onset of preeclampsia. Hypertens Pregnancy 2002;21:77–83.
    • (2002) Hypertens Pregnancy , vol.21 , pp. 77-83
    • Zhong, X.Y.1    Holzgreve, W.2    Hahn, S.3
  • 14
    • 4444252913 scopus 로고    scopus 로고
    • Increased fetal DNA in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia
    • Cotter AM, Martin CM, O'leary JJ, Daly SF. Increased fetal DNA in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia. Am J Obstet Gynecol 2004;191:515–20.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 515-520
    • Cotter, A.M.1    Martin, C.M.2    O'leary, J.J.3    Daly, S.F.4
  • 15
    • 1542380964 scopus 로고    scopus 로고
    • Fetal DNA in maternal plasma as a screening variable for preeclampsia: a preliminary nonparametric analysis of detection rate in low-risk nonsymptomatic patients
    • Farina A, Sekizawa A, Sugito Y, et al. Fetal DNA in maternal plasma as a screening variable for preeclampsia: a preliminary nonparametric analysis of detection rate in low-risk nonsymptomatic patients. Prenat Diagn 2004;24:83–6.
    • (2004) Prenat Diagn , vol.24 , pp. 83-86
    • Farina, A.1    Sekizawa, A.2    Sugito, Y.3
  • 16
    • 1642423713 scopus 로고    scopus 로고
    • Two stage elevation of cell-free fetal DNA in maternal sera before onset of preeclampsia
    • Levine RJ, Qian C, Leshane ES, et al. Two stage elevation of cell-free fetal DNA in maternal sera before onset of preeclampsia. Am J Obstet Gynecol 2004;190:707–13.
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 707-713
    • Levine, R.J.1    Qian, C.2    Leshane, E.S.3
  • 17
    • 18744400795 scopus 로고    scopus 로고
    • Increased fetal RhD gene in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia
    • Cotter AM, Martin CM, O'leary JJ, Daly SF. Increased fetal RhD gene in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia. BJOG 2005;112:584–7.
    • (2005) BJOG , vol.112 , pp. 584-587
    • Cotter, A.M.1    Martin, C.M.2    O'leary, J.J.3    Daly, S.F.4
  • 18
    • 70350573382 scopus 로고    scopus 로고
    • First-trimester maternal plasma cell-free fetal DNA and preeclampsia
    • Sifakis S, Zaravinos A, Maiz N, et al. First-trimester maternal plasma cell-free fetal DNA and preeclampsia. Am J Obstet Gynecol 2009;201427.e1-7.
    • (2009) Am J Obstet Gynecol , vol.201
    • Sifakis, S.1    Zaravinos, A.2    Maiz, N.3
  • 19
    • 77953192532 scopus 로고    scopus 로고
    • Evaluation of a panel of circulating DNA, RNA and protein potential markers for pathologies of pregnancy
    • Galbiati S, Causarano V, Pinzani P, et al. Evaluation of a panel of circulating DNA, RNA and protein potential markers for pathologies of pregnancy. Clin Chem Lab Med 2010;48:791–4.
    • (2010) Clin Chem Lab Med , vol.48 , pp. 791-794
    • Galbiati, S.1    Causarano, V.2    Pinzani, P.3
  • 20
    • 22144459608 scopus 로고    scopus 로고
    • High levels of fetal cell-free DNA in maternal serum: a risk factor for spontaneous preterm delivery
    • Farina A, LeShane ES, Romero R, et al. High levels of fetal cell-free DNA in maternal serum: a risk factor for spontaneous preterm delivery. Am J Obstet Gynecol 2005;193:421–5.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 421-425
    • Farina, A.1    LeShane, E.S.2    Romero, R.3
  • 21
    • 84865702441 scopus 로고    scopus 로고
    • High levels of fetal DNA are associated with increased risk of spontaneous preterm delivery
    • Jakobsen TR, Clausen FB, Rode L, et al. High levels of fetal DNA are associated with increased risk of spontaneous preterm delivery. Prenat Diagn 2012;32:840–5.
    • (2012) Prenat Diagn , vol.32 , pp. 840-845
    • Jakobsen, T.R.1    Clausen, F.B.2    Rode, L.3
  • 22
    • 1542501831 scopus 로고    scopus 로고
    • Circulating cell-free fetal DNA in maternal serum appears to originate from cyto- and syncytio-trophoblastic cells
    • Flori E, Doray B, Gautier E, et al. Circulating cell-free fetal DNA in maternal serum appears to originate from cyto- and syncytio-trophoblastic cells. Case report Hum Reprod 2004;19:723–4.
    • (2004) Case report Hum Reprod , vol.19 , pp. 723-724
    • Flori, E.1    Doray, B.2    Gautier, E.3
  • 23
    • 1942501800 scopus 로고    scopus 로고
    • Detection of cell free placental DNA in maternal plasma: direct evidence from three cases of confined placental mosaicism
    • Masuzaki H, Miura K, Yoshiura KI, et al. Detection of cell free placental DNA in maternal plasma: direct evidence from three cases of confined placental mosaicism. J Med Genet 2004;41:289–92.
    • (2004) J Med Genet , vol.41 , pp. 289-292
    • Masuzaki, H.1    Miura, K.2    Yoshiura, K.I.3
  • 24
    • 33746643333 scopus 로고    scopus 로고
    • Trophoblastic oxidative stress and the release of cell-free feto-placental DNA
    • Tjoa ML, Cindrova-Davies T, Spasic-Boskovic O, et al. Trophoblastic oxidative stress and the release of cell-free feto-placental DNA. Am J Pathol 2006;169:400–4.
    • (2006) Am J Pathol , vol.169 , pp. 400-404
    • Tjoa, M.L.1    Cindrova-Davies, T.2    Spasic-Boskovic, O.3
  • 25
    • 34347230507 scopus 로고    scopus 로고
    • Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast
    • Alberry M, Maddocks D, Jones M, et al. Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. Prenat Diagn 2007;2007(27):415–8.
    • (2007) Prenat Diagn , vol.2007 , Issue.27 , pp. 415-418
    • Alberry, M.1    Maddocks, D.2    Jones, M.3
  • 26
    • 84861419058 scopus 로고    scopus 로고
    • Non-invasive prenatal diagnosis of fetal aneuploidies using massively parallel sequencing-by-ligation and evidence that cell-free fetal DNA in the maternal plasma originates from cytotrophoblastic cells
    • Faas BH, deLigt J, Janssen I, et al. Non-invasive prenatal diagnosis of fetal aneuploidies using massively parallel sequencing-by-ligation and evidence that cell-free fetal DNA in the maternal plasma originates from cytotrophoblastic cells. Expert Opin Biol Ther 2012;S1:S19–26.
    • (2012) Expert Opin Biol Ther , vol.S1 , pp. S19-26
    • Faas, B.H.1    de Ligt, J.2    Janssen, I.3
  • 27
    • 0031799092 scopus 로고    scopus 로고
    • Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies
    • Knight M, Redman CW, Linton EA, Sargent IL. Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies. Br J Obstet Gynaecol 1998;105:632–40.
    • (1998) Br J Obstet Gynaecol , vol.105 , pp. 632-640
    • Knight, M.1    Redman, C.W.2    Linton, E.A.3    Sargent, I.L.4
  • 28
    • 84940462635 scopus 로고    scopus 로고
    • The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia
    • Hartley JD, Ferguson BJ, Moffett A. The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia. Am J Obstet Gynecol 2015;213:268–77.
    • (2015) Am J Obstet Gynecol , vol.213 , pp. 268-277
    • Hartley, J.D.1    Ferguson, B.J.2    Moffett, A.3
  • 30
    • 84862059620 scopus 로고    scopus 로고
    • TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia
    • Scharfe-Nugent A, Corr SC, Carpenter SB, et al. TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia. J Immunol 2012;188:5706–12.
    • (2012) J Immunol , vol.188 , pp. 5706-5712
    • Scharfe-Nugent, A.1    Corr, S.C.2    Carpenter, S.B.3
  • 31
    • 84903455207 scopus 로고    scopus 로고
    • Cell-free fetal DNA--a trigger for parturition
    • Phillippe M. Cell-free fetal DNA--a trigger for parturition. N Engl J Med 2014;370(26):2534–6.
    • (2014) N Engl J Med , vol.370 , Issue.26 , pp. 2534-2536
    • Phillippe, M.1
  • 32
    • 80055090375 scopus 로고    scopus 로고
    • Free fetal DNA levels in patients at risk of preterm labour
    • Illanes S, Gomez R, Fornes R, et al. Free fetal DNA levels in patients at risk of preterm labour. Prenat Diagn 2011;31:1082–5.
    • (2011) Prenat Diagn , vol.31 , pp. 1082-1085
    • Illanes, S.1    Gomez, R.2    Fornes, R.3
  • 33
    • 84876002574 scopus 로고    scopus 로고
    • Quantification of maternal serum cell-free fetal DNA in early-onset preeclampsia
    • Yu H, Shen Y, Ge Q, et al. Quantification of maternal serum cell-free fetal DNA in early-onset preeclampsia. Int J Mol Sci 2013;14(4):7571–82.
    • (2013) Int J Mol Sci , vol.14 , Issue.4 , pp. 7571-7582
    • Yu, H.1    Shen, Y.2    Ge, Q.3
  • 34
    • 84878445851 scopus 로고    scopus 로고
    • Maternal plasma cell-free fetal and maternal DNA at 11-13 weeks' gestation: relation to fetal and maternal characteristics and pregnancy outcomes
    • Poon LC, Musci T, Song K, et al. Maternal plasma cell-free fetal and maternal DNA at 11-13 weeks' gestation: relation to fetal and maternal characteristics and pregnancy outcomes. Fetal Diagn Ther 2013;33:215–23.
    • (2013) Fetal Diagn Ther , vol.33 , pp. 215-223
    • Poon, L.C.1    Musci, T.2    Song, K.3
  • 35
    • 84920768414 scopus 로고    scopus 로고
    • Fetal fraction of cell-free DNA in maternal plasma in the prediction of spontaneous preterm delivery
    • Quezada MS, Francisco C, Dumitrascu-Biris D, et al. Fetal fraction of cell-free DNA in maternal plasma in the prediction of spontaneous preterm delivery. Ultrasound Obstet Gynecol 2015;45:101–5.
    • (2015) Ultrasound Obstet Gynecol , vol.45 , pp. 101-105
    • Quezada, M.S.1    Francisco, C.2    Dumitrascu-Biris, D.3
  • 36
    • 72149093490 scopus 로고    scopus 로고
    • Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction
    • Illanes S, Parra M, Serra R, et al. Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction. Prenat Diagn 2009;29(12):1118–22.
    • (2009) Prenat Diagn , vol.29 , Issue.12 , pp. 1118-1122
    • Illanes, S.1    Parra, M.2    Serra, R.3
  • 37
    • 84899910697 scopus 로고    scopus 로고
    • The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP
    • Tranquilli AL, Dekker G, Magee L, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP. Pregnancy Hypertens 2014;4:97–104.
    • (2014) Pregnancy Hypertens , vol.4 , pp. 97-104
    • Tranquilli, A.L.1    Dekker, G.2    Magee, L.3
  • 39
    • 85003382407 scopus 로고    scopus 로고
    • The Netherlands., [Accessed on 17 February 2016]
    • Dutch Society of Obstetrics and Gynaecology in Dutch: Nederlandse Vereniging Obstetrie en Gynaecologie(NVOG). Guideline diabetes mellitus and pregnancy, 2010, The Netherlands. Available at: http://www.nvog-documenten.nl/richtlijn [Accessed on 17 February 2016].
    • (2010) Guideline diabetes mellitus and pregnancy
  • 40
    • 85016096376 scopus 로고    scopus 로고
    • External validation of prognostic models to predict risk of gestational diabetes mellitus in one Dutch cohort: prospective multicentre cohort study
    • Lamain-de Ruiter M, Kwee A, Naaktgeboren CA, et al. External validation of prognostic models to predict risk of gestational diabetes mellitus in one Dutch cohort: prospective multicentre cohort study. BMJ 2016;354:i4338.
    • (2016) BMJ , vol.354 , pp. i4338
    • Lamain-de Ruiter, M.1    Kwee, A.2    Naaktgeboren, C.A.3
  • 41
    • 60049097613 scopus 로고    scopus 로고
    • Significant correlation between maternal body mass index at delivery and in the second trimester, and second trimester circulating total cell-free DNA levels
    • Lapaire O, Volgmann T, Grill S, et al. Significant correlation between maternal body mass index at delivery and in the second trimester, and second trimester circulating total cell-free DNA levels. Reprod Sci 2009;16:274–9.
    • (2009) Reprod Sci , vol.16 , pp. 274-279
    • Lapaire, O.1    Volgmann, T.2    Grill, S.3
  • 42
    • 84868195316 scopus 로고    scopus 로고
    • Increased death of adipose cells, a path to release cell-free DNA into systemic circulation of obese women
    • Haghiac M, Vora NL, Basu S, et al. Increased death of adipose cells, a path to release cell-free DNA into systemic circulation of obese women. Obesity 2012;20:2213–9.
    • (2012) Obesity , vol.20 , pp. 2213-2219
    • Haghiac, M.1    Vora, N.L.2    Basu, S.3
  • 43
    • 84943800213 scopus 로고    scopus 로고
    • Effects of maternal and fetal characteristics on cell-free fetal DNA fraction in maternal plasma
    • Zhou Y, Zhu Z, Gao Y, et al. Effects of maternal and fetal characteristics on cell-free fetal DNA fraction in maternal plasma. Reprod Sci 2015;22:1429–35.
    • (2015) Reprod Sci , vol.22 , pp. 1429-1435
    • Zhou, Y.1    Zhu, Z.2    Gao, Y.3
  • 44
    • 84919460517 scopus 로고    scopus 로고
    • Maternal smoking does not affect the amount of cell-free fetal DNA in maternal plasma during the 1st trimester of pregnancy
    • Tarquini F, Picchiassi E, Centra M, et al. Maternal smoking does not affect the amount of cell-free fetal DNA in maternal plasma during the 1st trimester of pregnancy. J Obstet Gynaecol 2015;35:42–5.
    • (2015) J Obstet Gynaecol , vol.35 , pp. 42-45
    • Tarquini, F.1    Picchiassi, E.2    Centra, M.3
  • 45
    • 17044362698 scopus 로고    scopus 로고
    • The adverse effects of maternal smoking on the human placenta: a review
    • Zdravkovic T, Genbacev O, McMaster MT, Fisher SJ. The adverse effects of maternal smoking on the human placenta: a review. Placenta 2005;26(Suppl A):S81–6.
    • (2005) Placenta , vol.26 , pp. S81-S86
    • Zdravkovic, T.1    Genbacev, O.2    McMaster, M.T.3    Fisher, S.J.4
  • 46
    • 62549120316 scopus 로고    scopus 로고
    • Effects of maternal cigarette smoking on placental volume and vascularization measured by 3-dimensional power Doppler ultrasonography at 11 + 0 to 13 + 6 weeks of gestation
    • Rizzo G, Capponi A, Pietrolucci ME, Arduini D. Effects of maternal cigarette smoking on placental volume and vascularization measured by 3-dimensional power Doppler ultrasonography at 11 + 0 to 13 + 6 weeks of gestation. Am J Obstet Gynecol 2009;200415.e1-5.
    • (2009) Am J Obstet Gynecol , vol.200
    • Rizzo, G.1    Capponi, A.2    Pietrolucci, M.E.3    Arduini, D.4
  • 47
    • 23844476733 scopus 로고    scopus 로고
    • Placental volume, as measured by 3-dimensional sonography and levels of maternal plasma cell-free fetal DNA
    • Wataganara T, Metzenbauer M, Peter I, et al. Placental volume, as measured by 3-dimensional sonography and levels of maternal plasma cell-free fetal DNA. Am J Obstet Gynecol 2005;193:496–500.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 496-500
    • Wataganara, T.1    Metzenbauer, M.2    Peter, I.3
  • 48
    • 84871536941 scopus 로고    scopus 로고
    • Fetal fraction in maternal plasma cell-free DNA at 11-13 weeks' gestation: relation to maternal and fetal characteristics
    • Ashoor G, Syngelaki A, Poon LC, et al. Fetal fraction in maternal plasma cell-free DNA at 11-13 weeks' gestation: relation to maternal and fetal characteristics. Ultrasound Obstet Gynecol 2013;41:26–32.
    • (2013) Ultrasound Obstet Gynecol , vol.41 , pp. 26-32
    • Ashoor, G.1    Syngelaki, A.2    Poon, L.C.3
  • 49
    • 33750548645 scopus 로고    scopus 로고
    • Cell-free DNA levels in pregnancies at risk of sickle-cell disease and significant ethnic variation
    • Gerovassili A, Nicolaides KH, Thein SL, Rees DC. Cell-free DNA levels in pregnancies at risk of sickle-cell disease and significant ethnic variation. Br J Haematol 2006;135:738–41.
    • (2006) Br J Haematol , vol.135 , pp. 738-741
    • Gerovassili, A.1    Nicolaides, K.H.2    Thein, S.L.3    Rees, D.C.4
  • 50
    • 20444409135 scopus 로고    scopus 로고
    • Latest advances in understanding preeclampsia
    • Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science 2005;308:1592–4.
    • (2005) Science , vol.308 , pp. 1592-1594
    • Redman, C.W.1    Sargent, I.L.2
  • 51
    • 84859896759 scopus 로고    scopus 로고
    • Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal underperfusion
    • Soto E, Romero R, Kusanovic JP, et al. Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal underperfusion. J Matern Fetal Neonatal Med 2012;25:498–507.
    • (2012) J Matern Fetal Neonatal Med , vol.25 , pp. 498-507
    • Soto, E.1    Romero, R.2    Kusanovic, J.P.3
  • 52
    • 77957278607 scopus 로고    scopus 로고
    • Relationships between cell-free DNA and serum analytes in the first and second trimesters of pregnancy
    • Vora NL, Johnson KL, Lambert-Messerlian G, et al. Relationships between cell-free DNA and serum analytes in the first and second trimesters of pregnancy. Obstet Gynecol 2010;116:673–8.
    • (2010) Obstet Gynecol , vol.116 , pp. 673-678
    • Vora, N.L.1    Johnson, K.L.2    Lambert-Messerlian, G.3
  • 53
    • 0141726744 scopus 로고    scopus 로고
    • Expression of pregnancy-associated plasma protein-A (PAPP-A) during human villous trophoblast differentiation in vitro
    • Guibourdenche J, Frendo JL, Pidoux G, et al. Expression of pregnancy-associated plasma protein-A (PAPP-A) during human villous trophoblast differentiation in vitro. Placenta 2003;24:532–9.
    • (2003) Placenta , vol.24 , pp. 532-539
    • Guibourdenche, J.1    Frendo, J.L.2    Pidoux, G.3
  • 54
    • 0037245823 scopus 로고    scopus 로고
    • Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies
    • Taylor RN, Grimwood J, Taylor RS, et al. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol 2003;188:177–82.
    • (2003) Am J Obstet Gynecol , vol.188 , pp. 177-182
    • Taylor, R.N.1    Grimwood, J.2    Taylor, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.