Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice

Journal of Allergy and Clinical Immunology

Volumn 139, Issue 4, 2017, Pages 1253-1265.e14

  Gillis, Caitlin M ^a,b,c   Jönsson, Friederike ^a,b   Mancardi, David A ^a,b   Tu, Naxin ^e   Beutier, Héloïse ^a,b,c   Van Rooijen, Nico ^d   Macdonald, Lynn E ^e   Murphy, Andrew J ^e   Bruhns, Pierre ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Anaphylaxis; basophil; histamine; human Fc R; IgG; knock in mouse model; macrophage; monocyte; neutrophil; platelet activating factor

Indexed keywords

ANTIHISTAMINIC AGENT; CD14 ANTIGEN; CETIRIZINE; FC GAMMA RECEPTOR IIIA; FC GAMMA RECEPTOR IIIB; FC RECEPTOR IIA; FC RECEPTOR IIB; FCGR2B PROTEIN; FCGR3 PROTEIN; FCGR4 PROTEIN; HISTAMINE RECEPTOR 1 BLOCK; IMMUNOGLOBULIN G; IMMUNOGLOBULIN RECEPTOR; MEPYRAMINE; PROTEIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; TRIPROLIDINE; UNCLASSIFIED DRUG; FC RECEPTOR; FCGR2B PROTEIN, HUMAN; FCGR3A PROTEIN, HUMAN; FCGR3B PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BACTERIAL ARTIFICIAL CHROMOSOME; BASOPHIL; BLOOD; BONE MARROW; BONE MARROW CELL; CHROMOSOME 1; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYONIC STEM CELL; EOSINOPHIL; GENE EXPRESSION; GENE LOCUS; GENE TARGETING; GRANULOCYTE; HUMAN; HUMAN CELL; HYPOTHERMIA; IMMUNIZATION; IMMUNOCOMPETENT CELL; LUNG LAVAGE; LYMPH NODE; MACROPHAGE; MAST CELL; MONOCYTE; MORTALITY; MOUSE; MOUSE STRAIN; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PERITONEUM; PRIORITY JOURNAL; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION; SPLEEN; SYSTEMIC ANAPHYLAXIS; 129 MOUSE; ANAPHYLAXIS; ANIMAL; C57BL MOUSE; DISEASE MODEL; IMMUNOLOGY;

ANAPHYLAXIS; ANIMALS; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; GPI-LINKED PROTEINS; HUMANS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; RECEPTORS, IGG;

EID: 85002369837     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.06.058     Document Type: Article

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