Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 1, 2015, Pages 125-134.e12

  Patil, Sarita U ^a,b   Ogunniyi, Adebola O ^b   Calatroni, Agustin ^c   Tadigotla, Vasisht R ^d   Ruiter, Bert ^a   Ma, Alex ^a   Moon, James ^a   Love, J Christopher ^b   Shreffler, Wayne G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Rho   (United States)

^d Boston University   (United States)

Author keywords

antibody repertoire; antigen specific B cells; food allergy; Immunotherapy; peanut allergy

Indexed keywords

ARA H 2; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN MU CHAIN; PLASMID DNA; POLYMER; RECOMBINANT ANTIBODY; UNCLASSIFIED DRUG; ARA H 2 ALLERGEN, ARACHIS HYPOGAEA; EPITOPE; GLYCOPROTEIN; IMMUNOGLOBULIN E; NAPIN; PLANT ANTIGEN;

ADOLESCENT; ADULT; ANTIGEN SPECIFICITY; ARTICLE; BASOPHIL; CELL EXPANSION; CHILD; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; MEMORY CELL; NEXT GENERATION SEQUENCING; ORAL IMMUNOTHERAPY; OUTCOME ASSESSMENT; PEANUT; PEANUT ALLERGY; PEANUT ORAL IMMUNOTHERAPY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANTIBODY PRODUCTION; B LYMPHOCYTE; CELL CLONE; CELL CULTURE; CELL PROLIFERATION; DESENSITIZATION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; ORAL DRUG ADMINISTRATION; PEANUT HYPERSENSITIVITY; PROCEDURES;

2S ALBUMINS, PLANT; ADMINISTRATION, ORAL; ADOLESCENT; ANTIBODY FORMATION; ANTIGENS, PLANT; B-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CHILD; CLONE CELLS; DESENSITIZATION, IMMUNOLOGIC; EPITOPES; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULIN E; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MALE; PEANUT HYPERSENSITIVITY;

EID: 84949116714     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.03.026     Document Type: Article

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