IL-4/IL-13–mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury

Kidney International

Volumn 91, Issue 2, 2017, Pages 375-386

  Zhang, Ming Zhi ^a,b   Wang, Xin ^a   Wang, Yinqiu ^a   Niu, Aolei ^a   Wang, Suwan ^a   Zou, Chenhang ^a   Harris, Raymond C ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

ischemia reperfusion; macrophage polarization; STAT6; tofacitinib

Indexed keywords

BIOLOGICAL MARKER; DIPHTHERIA TOXIN RECEPTOR; INTERLEUKIN 3; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; TOFACITINIB; UNCLASSIFIED DRUG; DIPHTHERIA TOXIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTERLEUKIN 13; JAK3 PROTEIN, MOUSE; JANUS KINASE 3; STAT6 PROTEIN; STAT6 PROTEIN, MOUSE;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME ACTIVITY; GENE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; JAK-STAT SIGNALING; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; M2A GENE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; 129 MOUSE; ANIMAL; BAGG ALBINO MOUSE; CELL PLASTICITY; CONVALESCENCE; DEFICIENCY; DISEASE MODEL; FIBROSIS; GENETICS; GENOTYPE; KIDNEY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR;

ACUTE KIDNEY INJURY; ANIMALS; CELL PLASTICITY; DENDRITIC CELLS; DIPHTHERIA TOXIN; DISEASE MODELS, ANIMAL; FIBROSIS; GENOTYPE; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; INTERLEUKIN-13; INTERLEUKIN-4; JANUS KINASE 3; KIDNEY; MACROPHAGES; MALE; MICE, 129 STRAIN; MICE, INBRED BALB C; MICE, KNOCKOUT; PHENOTYPE; RECOVERY OF FUNCTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TIME FACTORS;

EID: 85002198102     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.08.020     Document Type: Article

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