The Relationship of Nosocomial Infection Reduction to Changes in Neonatal Intensive Care Unit Rates of Bronchopulmonary Dysplasia

Journal of Pediatrics

Volumn 180, Issue , 2017, Pages 105-109.e1

  Lapcharoensap, Wannasiri ^a,b   Kan, Peiyi ^c,d   Powers, Richard J ^e   Shaw, Gary M ^c,d   Stevenson, David K ^c,d   Gould, Jeffrey B ^b,c,d   Wirtschafter, David D ^f   Lee, Henry C ^b,c,d  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b California Perinatal Quality Care Collaborative   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d STANFORD UNIVERSITY   (United States)

^e Pediatrix Medical Group   (United States)

^f David D Wirtschafter Inc   (United States)

Author keywords

neonatal; quality improvement

Indexed keywords

APGAR SCORE; ARTICLE; BIRTH WEIGHT; CALIFORNIA; CHORIOAMNIONITIS; COHORT ANALYSIS; COMORBIDITY; CORTICOSTEROID THERAPY; FEMALE; GESTATIONAL AGE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION PREVENTION; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; NEONATAL INTENSIVE CARE UNIT; NEWBORN; NEWBORN MORBIDITY; POPULATION RESEARCH; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SMALL FOR DATE INFANT; BRONCHOPULMONARY DYSPLASIA; CLINICAL TRIAL; COMPLICATION; CROSS INFECTION; MULTICENTER STUDY; TIME FACTOR;

BRONCHOPULMONARY DYSPLASIA; COHORT STUDIES; CROSS INFECTION; FEMALE; HUMANS; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; MALE; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 85002196333     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2016.09.030     Document Type: Article

References (37)

1. 1 Patel, R.M., Kandefer, S., Walsh, M.C., Bell, E.F., Carlo, W.A., Laptook, A.R., et al. Causes and timing of death in extremely premature infants from 2000 through 2011. N Engl J Med 372 (2015), 331–340.
2. 2 Stoll, B.J., Hansen, N.I., Bell, E.F., Walsh, M.C., Carlo, W.A., Shankaran, S., et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA 314 (2015), 1039–1051.
3. 3 Bose, C.L., Dammann, C.E., Laughon, M.M., Bronchopulmonary dysplasia and inflammatory biomarkers in the premature neonate. Arch Dis Child Fetal Neonatal Ed 93 (2008), F455–61.
4. 4 Ryan, R.M., Ahmed, Q., Lakshminrusimha, S., Inflammatory mediators in the immunobiology of bronchopulmonary dysplasia. Clin Rev Allergy Immunol 34 (2008), 174–190.
5. 5 Speer, C.P., Pulmonary inflammation and bronchopulmonary dysplasia. J Perinatol 26:suppl 1 (2006), S57–62 discussion S3-4.
6. 6 Beeton, M.L., Maxwell, N.C., Davies, P.L., Nuttall, D., McGreal, E., Chakraborty, M., et al. Role of pulmonary infection in the development of chronic lung disease of prematurity. Eur Respir J 37 (2011), 1424–1430.
7. 7 Groneck, P., Gotze-Speer, B., Oppermann, M., Eiffert, H., Speer, C.P., Association of pulmonary inflammation and increased microvascular permeability during the development of bronchopulmonary dysplasia: a sequential analysis of inflammatory mediators in respiratory fluids of high-risk preterm neonates. Pediatrics 93 (1994), 712–718.
8. 8 Kotecha, S., Chan, B., Azam, N., Silverman, M., Shaw, R.J., Increase in interleukin-8 and soluble intercellular adhesion molecule-1 in bronchoalveolar lavage fluid from premature infants who develop chronic lung disease. Arch Dis Child Fetal Neonatal Ed 72 (1995), F90–6.
9. 9 Adams-Chapman, I., Long-term impact of infection on the preterm neonate. Semin Perinatol 36 (2012), 462–470.
10. 10 Bhandari, V., Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol 100 (2014), 189–201.
11. 11 Husain, A.N., Siddiqui, N.H., Stocker, J.T., Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia. Hum Pathol 29 (1998), 710–717.
12. 12 Jobe, A.H., The new bronchopulmonary dysplasia. Curr Opin Pediatr 23 (2011), 167–172.
13. 13 Parker, T.A., Abman, S.H., The pulmonary circulation in bronchopulmonary dysplasia. Semin Neonatol 8 (2003), 51–61.
14. 14 Shah, J., Jefferies, A.L., Yoon, E.W., Lee, S.K., Shah, P.S., on behalf of the Canadian Neonatal Network. Risk factors and outcomes of late-onset bacterial sepsis in preterm neonates born at < 32 weeks' gestation. Am J Perinatol 32 (2014), 675–682.
15. 15 Pryhuber, G.S., Postnatal infections and immunology affecting chronic lung disease of prematurity. Clin Perinatol 42 (2015), 697–718.
16. 16 Lahra, M.M., Beeby, P.J., Jeffery, H.E., Intrauterine inflammation, neonatal sepsis, and chronic lung disease: a 13-year hospital cohort study. Pediatrics 123 (2009), 1314–1319.
17. 17 Liljedahl, M., Bodin, L., Schollin, J., Coagulase-negative staphylococcal sepsis as a predictor of bronchopulmonary dysplasia. Acta Paediatr 93 (2004), 211–215.
18. 18 Rojas, M.A., Gonzalez, A., Bancalari, E., Claure, N., Poole, C., Silva-Neto, G., Changing trends in the epidemiology and pathogenesis of neonatal chronic lung disease. J Pediatr 126 (1995), 605–610.
19. 19 Van Marter, L.J., Dammann, O., Allred, E.N., Leviton, A., Pagano, M., Moore, M., et al. Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants. J Pediatr 140 (2002), 171–176.
20. 20 Stoll, B.J., Hansen, N., Infections in VLBW infants: studies from the NICHD Neonatal Research Network. Semin Perinatol 27 (2003), 293–301.
21. 21 Stoll, B.J., Hansen, N., Fanaroff, A.A., Wright, L.L., Carlo, W.A., Ehrenkranz, R.A., et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 110 (2002), 285–291.
22. 22 Bloom, B.T., Craddock, A., Delmore, P.M., Kurlinski, J.P., Voelker, M., Landfish, N., et al. Reducing acquired infections in the NICU: observing and implementing meaningful differences in process between high and low acquired infection rate centers. J Perinatol 23 (2003), 489–492.
23. 23 Ng, P.C., Wong, H.L., Lyon, D.J., So, K.W., Liu, F., Lam, R.K., et al. Combined use of alcohol hand rub and gloves reduces the incidence of late onset infection in very low birthweight infants. Arch Dis Child Fetal Neonatal Ed 89 (2004), F336–40.
24. 24 Resende, D.S., Peppe, A.L., dos Reis, H., Abdallah, V.O., Ribas, R.M., Gontijo Filho, P.P., Late onset sepsis in newborn babies: epidemiology and effect of a bundle to prevent central line associated bloodstream infections in the neonatal intensive care unit. Braz J Infect Dis 19 (2015), 52–57.
25. 25 Wirtschafter, D.D., Pettit, J., Kurtin, P., Dalsey, M., Chance, K., Morrow, H.W., et al. A statewide quality improvement collaborative to reduce neonatal central line-associated blood stream infections. J Perinatol 30 (2010), 170–181.
26. 26 Wirtschafter, D.D., Powers, R.J., Pettit, J.S., Lee, H.C., Boscardin, W.J., Ahmad Subeh, M., et al. Nosocomial infection reduction in VLBW infants with a statewide quality-improvement model. Pediatrics 127 (2011), 419–426.
27. 27 Kaplan, H.C., Lannon, C., Walsh, M.C., Donovan, E.F., Ohio Perinatal Quality Collaborative. Ohio statewide quality-improvement collaborative to reduce late-onset sepsis in preterm infants. Pediatrics 127 (2011), 427–435.
28. 28 Payne, N.R., Barry, J., Berg, W., Brasel, D.E., Hagen, E.A., Matthews, D., et al. Sustained reduction in neonatal nosocomial infections through quality improvement efforts. Pediatrics 129 (2012), e165–73.
29. 29 Vermont Oxford Network, Vermont Oxford Network Database Summary for Infants 501 to 1500 Grams Born in 2011. Burlington (VT): Vermont Oxford Network, 2012.
30. 30 Payne, N.R., LaCorte, M., Karna, P., Chen, S., Finkelstein, M., Goldsmith, J.P., et al. Reduction of bronchopulmonary dysplasia after participation in the Breathsavers Group of the Vermont Oxford Network Neonatal Intensive Care Quality Improvement Collaborative. Pediatrics 118:suppl 2 (2006), S73–7.
31. 31 Lapcharoensap, W., Gage, S.C., Kan, P., Profit, J., Shaw, G.M., Gould, J.B., et al. Hospital variation and risk factors for bronchopulmonary dysplasia in a population-based cohort. JAMA Pediatr, 169, 2015, e143676.
32. 32 Adams-Chapman, I., Stoll, B.J., Prevention of nosocomial infections in the neonatal intensive care unit. Curr Opin Pediatr 14 (2002), 157–164.
33. 33 Borghesi, A., Stronati, M., Strategies for the prevention of hospital-acquired infections in the neonatal intensive care unit. J Hosp Infect 68 (2008), 293–300.
34. 34 Bowen, J.R., Callander, I., Richards, R., Lindrea, K.B., Sepsis Prevention in NICUs Group. Decreasing infection in neonatal intensive care units through quality improvement. Arch Dis Child Fetal Neonatal Ed, 2016, 10.1136/archdischild-2015-310165 [Epub ahead of print].
35. 35 Strunk, T., Inder, T., Wang, X., Burgner, D., Mallard, C., Levy, O., Infection-induced inflammation and cerebral injury in preterm infants. Lancet Infect Dis 14 (2014), 751–762.
36. 36 Wynn, J.L., Defining neonatal sepsis. Curr Opin Pediatr 28 (2016), 135–140.
37. 37 Walsh, M., Laptook, A., Kazzi, S.N., Engle, W.A., Yao, Q., Rasmussen, M., et al. A cluster-randomized trial of benchmarking and multimodal quality improvement to improve rates of survival free of bronchopulmonary dysplasia for infants with birth weights of less than 1250 grams. Pediatrics 119 (2007), 876–890.