Sustained reduction in neonatal nosocomial infections through quality improvement efforts

Pediatrics

Volumn 129, Issue 1, 2012, Pages

  Payne, Nathaniel R ^a   Barry, Jennifer ^a   Berg, Wendy ^a   Brasel, David E ^a   Hagen, Erik A ^a   Matthews, Debra ^a   McCullough, Kristin ^a   Sanger, Katherine ^a   Steger, Melissa D ^a  

^a CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

Author keywords

Neonatal care; Neonatal morbidity; NICU; Nosocomial infections; Quality improvement

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; FEMALE; HEALTH CARE QUALITY; HOSPITAL INFECTION; HUMAN; INFANT; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; NEWBORN INFECTION; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TOTAL QUALITY MANAGEMENT; UNITED STATES; VERY LOW BIRTH WEIGHT; WEIGHT GAIN;

CATHETER-RELATED INFECTIONS; CROSS INFECTION; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE UNITS, NEONATAL; QUALITY IMPROVEMENT;

EID: 84855283223     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2011-0566     Document Type: Article

References (45)

1. Stoll BJ, Hansen N, Fanaroff AA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics. 2002;110(2 Pt 1):285-291 (Pubitemid 34833012)
2. Aziz K, McMillan DD, Andrews W, et al. Canadian Neonatal Network. Variations in rates of nosocomial infection among Canadian neonatal intensive care units may be practice-related. BMC Pediatr. 2005;5(1):22
3. Vermont Oxford Network. 2009 Very Low Birth Weight Quality Management Report for Center 105. Burlington, VT: Vermont Oxford Network; 2009 [available on request from corresponding author].
4. Kilbride HW, Wirtschafter DD, Powers RJ, Sheehan MB. Implementation of evidence-based potentially better practices to decrease nosocomial infections. Pediatrics. 2003;111(4 Pt 2):e519-e533
5. Horbar JD, Rogowski J, Plsek PE, et al. Collaborative quality improvement for neonatal intensive care.NIC/Q Project Investigators of the Vermont Oxford Network. Pediatrics. 2001;107(1):14-22 (Pubitemid 32055409)
6. Hernández-Ronquillo L, Téllez-Zenteno JF, Weder-Cisneros N, Salinas-Ramírez V, Zapata-Pallagi JA, da Silva O. Risk factors for the development of bronchopulmonary dysplasia: a case-control study. Arch Med Res. 2004;35(6):549-553 (Pubitemid 41043629)
7. Payne NR, Carpenter JH, Badger GJ, Horbar JD, Rogowski J. Marginal increase in cost and excess length of stay associated with nosocomial bloodstream infections in surviving very low birth weight infants. Pediatrics. 2004;114(2):348-355 (Pubitemid 39006660)
8. Capretti MG, Sandri F, Tridapalli E, Galletti S, Petracci E, Faldella G. Impact of a standardized hand hygiene program on the incidence of nosocomial infection in very low birth weight infants. Am J Infect Control. 2008;36(6):430-435
9. Cotten CM, Oh W, McDonald S, et al. NICHD Neonatal Research Network. Prolonged hospital stay for extremely premature infants: risk factors, center differences, and the impact of mortality on selecting a best-performing center. J Perinatol. 2005;25(10):650-655 (Pubitemid 41486252)
10. Stoll BJ, Hansen NI, Bell EF, et al. Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics. 2010;126(3):443-456
11. Bassler D, Stoll BJ, Schmidt B, et al. Trial of Indomethacin Prophylaxis in Preterms Investigators. Using a count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection. Pediatrics. 2009;123(1):313-318
12. Stoll BJ, Hansen NI, Adams-Chapman I, et al. National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection. JAMA. 2004;292(19):2357-2365 (Pubitemid 39491920)
13. Clapp DW. Developmental regulation of the immune system. Semin Perinatol. 2006;30(2):69-72 (Pubitemid 43767138)
14. Garland JS, Alex CP, Sevallius JM, et al. Cohort study of the pathogenesis and molecular epidemiology of catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters. Infect Control Hosp Epidemiol. 2008;29(3):243-249 (Pubitemid 351269190)
15. Kilbride HW, Powers R, Wirtschafter DD, et al. Evaluation and development of potentially better practices to prevent neonatal nosocomial bacteremia. Pediatrics. 2003;111(4 Pt 2):e504-e518
16. Payne NR, Finkelstein MJ, Liu M, Kaempf JW, Sharek PJ, Olsen S. NICU practices and outcomes associated with 9 years of quality improvement collaboratives. Pediatrics. 2010;125(3):437-446
17. Lee SK, Aziz K, Singhal N, et al. Improving the quality of care for infants: a cluster randomized controlled trial. CMAJ. 2009;181(8):469-476
18. Wirtschafter DD, Pettit J, Kurtin P, et al. A statewide quality improvement collaborative to reduce neonatal central line-associated blood stream infections. J Perinatol. 2010;30(3):170-181
19. Garland JS, Alex CP, Henrickson KJ, McAuliffe TL, Maki DG. A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial. Pediatrics. 2005;116(2):e198-e205 (Pubitemid 44161440)
20. Schelonka RL, Scruggs S, Nichols K, Dimmitt RA, Carlo WA. Sustained reductions in neonatal nosocomial infection rates following a comprehensive infection control intervention. J Perinatol. 2006;26(3):176-179
21. Schwab F, Geffers C, Bärwolff S, Rüden H, Gastmeier P. Reducing neonatal nosocomial bloodstream infections through participation in a national surveillance system. J Hosp Infect. 2007;65(4):319-325 (Pubitemid 46477979)
22. Schulman J, Stricof RL, Stevens TP, et al. New York State Regional Perinatal Centers; New York State Department of Health. Development of a statewide collaborative to decrease NICU central line-associated bloodstream infections. J Perinatol. 2009;29(9):591-599
23. Bloom BT, Craddock A, Delmore PM, et al. Reducing acquired infections in the NICU: observing and implementing meaningful differences in process between high and low acquired infection rate centers. J Perinatol. 2003;23(6):489-492 (Pubitemid 37258566)
24. Stark AR; American Academy of Pediatrics Committee on Fetus and Newborn. Levels of neonatal care. Pediatrics. 2004;114(5):1341-1347
25. Toltzis P, Walsh M. Recently tested strategies to reduce nosocomial infections in the neonatal intensive care unit. Expert Rev Anti Infect Ther. 2010;8(2):235-242
26. O'Grady NP, Alexander M, Dellinger EP, et al. Guidelines for the prevention of intravascular catheter-related infections. MMWR. 2002;51(RR-10):1-26.
27. Guerin K, Wagner J, Rains K, Bessesen M. Reduction in central line-associated bloodstream infections by implementation of a postinsertion care bundle. Am J Infect Control. 2010;38(6):430-433
28. Ho KM, Litton E. Use of chlorhexidine-impregnated dressing to prevent vascular and epidural catheter colonization and infection: a meta-analysis. J Antimicrob Chemother. 2006;58(2):281-287 (Pubitemid 44294936)
29. Noorani A, Rabey N, Walsh SR, Davies RJ. Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery. Br J Surg. 2010;97(11):1614-1620
30. Chudleigh J, Fletcher M, Gould D. Infection control in neonatal intensive care units. J Hosp Infect. 2005;61(2):123-129 (Pubitemid 41288149)
31. Eldridge NE, Woods SS, Bonello RS, et al. Using the six sigma process to implement the Centers for Disease Control and Prevention Guideline for Hand Hygiene in 4 intensive care units. J Gen Intern Med. 2006;21(Suppl 2):S35-S42
32. Thomas LM. The changing role of parents in neonatal care: a historical review. Neonatal Netw. 2008;27(2):91-100
33. Vermont Oxford Network. Vermont Oxford Network Database Manual of Operations for Infants Born in 2005. Burlington, VT: VON; 2005.
34. Vermont Oxford Network Database Manual of Operations for Infants Born in 2009. Burlington, VT: VON; 2009.
35. Centers for Disease Control National Healthcare Safety Network. Device-Associated Module: Central line-associated bloodstream infection (CLABSI) event; March 2010. Available at: www.cdc.gov/nhsn/PDFs/pscManual/4PSC- CLABScurrent.pdf. Accessed January 21, 2011
36. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health careassociated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36(5):309-332 (Pubitemid 351763841)
37. VON. Nightingale website. Available at: https://nightingale.vtoxford.org. Accessed June 13, 2011
38. Kramer MS, Platt RW, Wen SW, et al. Fetal/Infant Health Study Group of the Canadian Perinatal Surveillance System. A new and improved population-based Canadian reference for birth weight for gestational age. Pediatrics. 2001;108(2):E35
39. Payne NR, LaCorte M, Karna P, et al. Breathsavers Group, Vermont Oxford Network Neonatal Intensive Care Quality Improvement Collaborative. Reduction of bronchopulmonary dysplasia after participation in the Breathsavers Group of the Vermont Oxford Network Neonatal Intensive Care Quality Improvement Collaborative. Pediatrics. 2006;118(Suppl 2):S73-S77 (Pubitemid 46397621)
40. Curry S, Honeycutt M, Goins G, Gilliam C. Catheter-associated bloodstream infections in the NICU: getting to zero. Neonatal Netw. 2009;28(3):151-155
41. Kramer BW, Kallapur S, Newnham J, Jobe AH. Prenatal inflammation and lung development. Semin Fetal Neonatal Med. 2009;14(1):2-7
42. Pronovost P, Needham D, Berenholtz S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):2725-2732 (Pubitemid 46021509)
43. Cooley K, Grady S. Minimizing catheter-related bloodstream infections: one unit's approach. Adv Neonatal Care. 2009;9(5):209-226, quiz 227-228
44. Parry GJ, Tucker JS, Tarnow-Mordi WO; UK Neonatal Staffing Study Group. Relationship between probable nosocomial bacteraemia and organisational and structural factors in UK neonatal intensive care units. Qual Saf Health Care. 2005;14(4):264-269 (Pubitemid 41133180)
45. Sannoh S, Clones B, Munoz J, Montecalvo M, Parvez B. A multimodal approach to central venous catheter hub care can decrease catheter-related bloodstream infection. Am J Infect Control. 2010;38(6):424-429