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Volumn 120, Issue 2, 2017, Pages 341-353

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

(117)  Jones, Gregory T a   Tromp, Gerard d   Kuivaniemi, Helena d,f   Gretarsdottir, Solveig g   Baas, Annette F h   Giusti, Betti j   Strauss, Ewa l,m   Van'T Hof, Femke N G a   Webb, Thomas R n,o   Erdman, Robert d   Ritchie, Marylyn D e,p   Elmore, James R q   Verma, Anurag p   Pendergrass, Sarah e,p   Kullo, Iftikhar J r   Ye, Zi r   Peissig, Peggy L i,s   Gottesman, Omri m,t   Verma, Shefali S a,p   Malinowski, Jennifer u   more..


Author keywords

aortic aneurysm abdominal; computational biology; genetics; genome wide association study; matrix metalloproteinases; meta analysis

Indexed keywords

GELATINASE B; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN RECEPTOR; ZINC FINGER PROTEIN;

EID: 85002194690     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.308765     Document Type: Article
Times cited : (161)

References (61)
  • 1
    • 65649094104 scopus 로고    scopus 로고
    • In the clinic. Abdominal aortic aneurysm
    • Lederle FA. In the clinic. Abdominal aortic aneurysm. Ann Intern Med. 2009;150:ITC5-ITC1. doi: 10.7326/0003-4819-150-9-200905050-01005.
    • (2009) Ann Intern Med , vol.150 , pp. ITC1-ITC5
    • Lederle, F.A.1
  • 2
    • 84895797047 scopus 로고    scopus 로고
    • Ultrasonography screening for abdominal aortic aneurysms: A systematic evidence review for the U.S Preventive Services Task Force
    • Guirguis-Blake JM, Beil TL, Senger CA, Whitlock EP. Ultrasonography screening for abdominal aortic aneurysms: a systematic evidence review for the U.S. Preventive Services Task Force. Ann Intern Med. 2014;160:321-329. doi: 10.7326/M13-1844.
    • (2014) Ann Intern Med , vol.160 , pp. 321-329
    • Guirguis-Blake, J.M.1    Beil, T.L.2    Senger, C.A.3    Whitlock, E.P.4
  • 3
    • 85009922732 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm screening: 2014 to 2015 data. The NHS AAA Screening Programme.. Accessed July 12
    • Abdominal aortic aneurysm screening: 2014 to 2015 data. The NHS AAA Screening Programme. https://www.gov.uk/government/publications/abdominal-aortic-aneurysm-screening-2014-to-2015-data. Accessed July 12, 2016.
    • (2016)
  • 4
    • 72549087148 scopus 로고    scopus 로고
    • Genetic and environmental contributions to abdominal aortic aneurysm development in a twin population
    • discussion 7
    • Wahlgren CM, Larsson E, Magnusson PK, Hultgren R, Swedenborg J. Genetic and environmental contributions to abdominal aortic aneurysm development in a twin population. J Vasc Surg. 2010;51:3-7; discussion 7. doi: 10.1016/j.jvs.2009.08.036.
    • (2010) J Vasc Surg , vol.51 , pp. 3-7
    • Wahlgren, C.M.1    Larsson, E.2    Magnusson, P.K.3    Hultgren, R.4    Swedenborg, J.5
  • 5
    • 58549108408 scopus 로고    scopus 로고
    • A population-based casecontrol study of the familial risk of abdominal aortic aneurysm
    • discussion 51
    • Larsson E, Granath F, Swedenborg J, Hultgren R. A population-based casecontrol study of the familial risk of abdominal aortic aneurysm. J Vasc Surg. 2009;49:47-50; discussion 51. doi: 10.1016/j.jvs.2008.08.012.
    • (2009) J Vasc Surg , vol.49 , pp. 47-50
    • Larsson, E.1    Granath, F.2    Swedenborg, J.3    Hultgren, R.4
  • 6
    • 84947899513 scopus 로고    scopus 로고
    • Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
    • Gretarsdottir S, Baas AF, Thorleifsson G, et al. Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nat Genet. 2010;42:692-697. doi: 10.1038/ng.622.
    • (2010) Nat Genet , vol.42 , pp. 692-697
    • Gretarsdottir, S.1    Baas, A.F.2    Thorleifsson, G.3
  • 7
    • 84945173643 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
    • CARDioGRAM Consortium; Global BPgen Consortium; DiAGRAM Consortium; VRCNZ Consortium
    • Bown MJ, Jones GT, Harrison SC, et al; CARDioGRAM Consortium; Global BPgen Consortium; DiAGRAM Consortium; VRCNZ Consortium. Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. Am J Hum Genet. 2011;89:619-627. doi: 10.1016/j.ajhg.2011.10.002.
    • (2011) Am J Hum Genet , vol.89 , pp. 619-627
    • Bown, M.J.1    Jones, G.T.2    Harrison, S.C.3
  • 8
    • 84892385162 scopus 로고    scopus 로고
    • A variant in LDLR is associated with abdominal aortic aneurysm
    • Bradley DT, Hughes AE, Badger SA, et al. A variant in LDLR is associated with abdominal aortic aneurysm. Circ Cardiovasc Genet. 2013;6:498-504. doi: 10.1161/CIRCGENETICS.113.000165.
    • (2013) Circ Cardiovasc Genet , vol.6 , pp. 498-504
    • Bradley, D.T.1    Hughes, A.E.2    Badger, S.A.3
  • 9
    • 84880305065 scopus 로고    scopus 로고
    • A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm
    • Jones GT, Bown MJ, Gretarsdottir S, et al. A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Hum Mol Genet. 2013;22:2941-2947. doi: 10.1093/hmg/ddt141.
    • (2013) Hum Mol Genet , vol.22 , pp. 2941-2947
    • Jones, G.T.1    Bown, M.J.2    Gretarsdottir, S.3
  • 10
    • 84891514939 scopus 로고    scopus 로고
    • Interleukin-6 receptor pathways in abdominal aortic aneurysm
    • Aneurysm Consortium
    • Harrison SC, Smith AJ, Jones GT, et al; Aneurysm Consortium. Interleukin-6 receptor pathways in abdominal aortic aneurysm. Eur Heart J. 2013;34:3707-3716. doi: 10.1093/eurheartj/ehs354.
    • (2013) Eur Heart J , vol.34 , pp. 3707-3716
    • Harrison, S.C.1    Smith, A.J.2    Jones, G.T.3
  • 11
    • 38649091662 scopus 로고    scopus 로고
    • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
    • Helgadottir A, Thorleifsson G, Magnusson KP, et al. The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet. 2008;40:217-224. doi: 10.1038/ng.72.
    • (2008) Nat Genet , vol.40 , pp. 217-224
    • Helgadottir, A.1    Thorleifsson, G.2    Magnusson, K.P.3
  • 12
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics. 2010;26:2190-2191. doi: 10.1093/bioinformatics/btq340.
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 13
    • 18944381751 scopus 로고    scopus 로고
    • SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
    • Shi YY, He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res. 2005;15:97-98. doi: 10.1038/sj.cr.7290272.
    • (2005) Cell Res , vol.15 , pp. 97-98
    • Shi, Y.Y.1    He, L.2
  • 14
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han B, Eskin E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am J Hum Genet. 2011;88:586-598. doi: 10.1016/j.ajhg.2011.04.014.
    • (2011) Am J Hum Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 15
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DiAbetes Genetics Replication And Meta-analysis (DiAGRAM) Consortium
    • Morris AP, Voight BF, Teslovich TM, et al; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DiAbetes Genetics Replication And Meta-analysis (DiAGRAM) Consortium. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44:981-990. doi: 10.1038/ng.2383.
    • (2012) Nat Genet , vol.44 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3
  • 16
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Cardiogenics; CARDioGRAM Consortium
    • Schunkert H, König IR, Kathiresan S, et al; Cardiogenics; CARDioGRAM Consortium. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011;43:333-338. doi: 10.1038/ng.784.
    • (2011) Nat Genet , vol.43 , pp. 333-338
    • Schunkert, H.1    König, I.R.2    Kathiresan, S.3
  • 17
    • 84887099827 scopus 로고    scopus 로고
    • Discovery and refinement of loci associated with lipid levels
    • Willer CJ, Schmidt EM, Sengupta S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45:1274-1283
    • (2013) Nat Genet , vol.45 , pp. 1274-1283
    • Willer, C.J.1    Schmidt, E.M.2    Sengupta, S.3
  • 18
    • 80053383403 scopus 로고    scopus 로고
    • Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
    • LifeLines Cohort Study; EchoGen consortium; AortaGen Consortium; CHARGE Consortium Heart Failure Working Group; KidneyGen consortium; CKDGen consortium; Cardiogenics consortium; CardioGram
    • Wain LV, Verwoert GC, O'Reilly PF, et al; LifeLines Cohort Study; EchoGen consortium; AortaGen Consortium; CHARGE Consortium Heart Failure Working Group; KidneyGen consortium; CKDGen consortium; Cardiogenics consortium; CardioGram. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011;43:1005-1011. doi: 10.1038/ng.922.
    • (2011) Nat Genet , vol.43 , pp. 1005-1011
    • Wain, L.V.1    Verwoert, G.C.2    O'Reilly, P.F.3
  • 19
    • 84890802026 scopus 로고    scopus 로고
    • Phenotype-Genotype Integrator (PheGenI): Synthesizing genome-wide association study (GWAS) data with existing genomic resources
    • Ramos EM, Hoffman D, Junkins HA, Maglott D, Phan L, Sherry ST, Feolo M, Hindorff LA. Phenotype-Genotype Integrator (PheGenI): synthesizing genome-wide association study (GWAS) data with existing genomic resources. Eur J Hum Genet. 2014;22:144-147. doi: 10.1038/ejhg.2013.96.
    • (2014) Eur J Hum Genet , vol.22 , pp. 144-147
    • Ramos, E.M.1    Hoffman, D.2    Junkins, H.A.3    Maglott, D.4    Phan, L.5    Sherry, S.T.6    Feolo, M.7    Hindorff, L.A.8
  • 20
    • 84902511942 scopus 로고    scopus 로고
    • GRASP: Analysis of genotypephenotype results from 1390 genome-wide association studies and corresponding open access database
    • Leslie R, O'Donnell CJ, Johnson AD. GRASP: analysis of genotypephenotype results from 1390 genome-wide association studies and corresponding open access database. Bioinformatics. 2014;30:i185-i194. doi: 10.1093/bioinformatics/btu273.
    • (2014) Bioinformatics , vol.30 , pp. i185-i194
    • Leslie, R.1    O'Donnell, C.J.2    Johnson, A.D.3
  • 22
    • 84873488838 scopus 로고    scopus 로고
    • Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network
    • Pendergrass SA, Brown-Gentry K, Dudek S, et al. Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. PLoS Genet. 2013;9:e1003087. doi: 10.1371/journal.pgen.1003087.
    • (2013) PLoS Genet , vol.9 , pp. e1003087
    • Pendergrass, S.A.1    Brown-Gentry, K.2    Dudek, S.3
  • 23
    • 84880059657 scopus 로고    scopus 로고
    • The Electronic Medical Records and Genomics (eMERGE) Network: Past, present, and future
    • eMERGE Network
    • Gottesman O, Kuivaniemi H, Tromp G, et al; eMERGE Network. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genet Med. 2013;15:761-771. doi: 10.1038/gim.2013.72.
    • (2013) Genet Med , vol.15 , pp. 761-771
    • Gottesman, O.1    Kuivaniemi, H.2    Tromp, G.3
  • 24
    • 38549141226 scopus 로고    scopus 로고
    • Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases
    • Reumers J, Conde L, Medina I, Maurer-Stroh S, Van Durme J, Dopazo J, Rousseau F, Schymkowitz J. Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases. Nucleic Acids Res. 2008;36:D825-D829. doi: 10.1093/nar/gkm979.
    • (2008) Nucleic Acids Res , vol.36 , pp. D825-D829
    • Reumers, J.1    Conde, L.2    Medina, I.3    Maurer-Stroh, S.4    Van Durme, J.5    Dopazo, J.6    Rousseau, F.7    Schymkowitz, J.8
  • 25
    • 84883583576 scopus 로고    scopus 로고
    • GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications
    • Li MJ, Wang LY, Xia Z, Sham PC, Wang J. GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications. Nucleic Acids Res. 2013;41:W150-W158. doi: 10.1093/nar/gkt456.
    • (2013) Nucleic Acids Res , vol.41 , pp. W150-W158
    • Li, M.J.1    Wang, L.Y.2    Xia, Z.3    Sham, P.C.4    Wang, J.5
  • 26
    • 84923096381 scopus 로고    scopus 로고
    • Biological interpretation of genome-wide association studies using predicted gene functions
    • Genetic Investigation of ANthropometric Traits (GIANT) Consortium
    • Pers TH, Karjalainen JM, Chan Y, et al; Genetic Investigation of ANthropometric Traits (GIANT) Consortium. Biological interpretation of genome-wide association studies using predicted gene functions. Nat Commun. 2015;6:5890. doi: 10.1038/ncomms6890.
    • (2015) Nat Commun , vol.6 , pp. 5890
    • Pers, T.H.1    Karjalainen, J.M.2    Chan, Y.3
  • 28
    • 84923342405 scopus 로고    scopus 로고
    • Genome-wide significant loci: How important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders
    • Björkegren JL, Kovacic JC, Dudley JT, Schadt EE. Genome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders. J Am Coll Cardiol. 2015;65:830-845. doi: 10.1016/j.jacc.2014.12.033.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 830-845
    • Björkegren, J.L.1    Kovacic, J.C.2    Dudley, J.T.3    Schadt, E.E.4
  • 29
    • 38049186595 scopus 로고    scopus 로고
    • Aortic aneurysms: An immune disease with a strong genetic component
    • Kuivaniemi H, Platsoucas CD, Tilson MD III. Aortic aneurysms: an immune disease with a strong genetic component. Circulation. 2008;117:242-252. doi: 10.1161/CIRCULATIONAHA.107.690982.
    • (2008) Circulation , vol.117 , pp. 242-252
    • Kuivaniemi, H.1    Platsoucas, C.D.2    Tilson, M.D.3
  • 31
    • 84930621520 scopus 로고    scopus 로고
    • Transcriptional (ChIP-Chip) analysis of ELF1, ETS2, RUNX1 and STAT5 in human abdominal aortic aneurysm
    • Pahl MC, Erdman R, Kuivaniemi H, Lillvis JH, Elmore JR, Tromp G. Transcriptional (ChIP-Chip) analysis of ELF1, ETS2, RUNX1 and STAT5 in human abdominal aortic aneurysm. Int J Mol Sci. 2015;16:11229-11258. doi: 10.3390/ijms160511229.
    • (2015) Int J Mol Sci , vol.16 , pp. 11229-11258
    • Pahl, M.C.1    Erdman, R.2    Kuivaniemi, H.3    Lillvis, J.H.4    Elmore, J.R.5    Tromp, G.6
  • 32
    • 84876008750 scopus 로고    scopus 로고
    • The ConsensusPathDB interaction database: 2013 update
    • Kamburov A, Stelzl U, Lehrach H, Herwig R. The ConsensusPathDB interaction database: 2013 update. Nucleic Acids Res. 2013;41:D793-D800. doi: 10.1093/nar/gks1055.
    • (2013) Nucleic Acids Res , vol.41 , pp. D793-D800
    • Kamburov, A.1    Stelzl, U.2    Lehrach, H.3    Herwig, R.4
  • 33
    • 77958500367 scopus 로고    scopus 로고
    • Evidence mining and novelty assessment of protein-protein interactions with the ConsensusPathDB plugin for Cytoscape
    • Pentchev K, Ono K, Herwig R, Ideker T, Kamburov A. Evidence mining and novelty assessment of protein-protein interactions with the ConsensusPathDB plugin for Cytoscape. Bioinformatics. 2010;26:2796-2797. doi: 10.1093/bioinformatics/btq522.
    • (2010) Bioinformatics , vol.26 , pp. 2796-2797
    • Pentchev, K.1    Ono, K.2    Herwig, R.3    Ideker, T.4    Kamburov, A.5
  • 34
    • 84930225536 scopus 로고    scopus 로고
    • LLY-507, a cell-active, potent, and selective inhibitor of protein-lysine methyltransferase SMYD2
    • Nguyen H, Allali-Hassani A, Antonysamy S, et al. LLY-507, a cell-active, potent, and selective inhibitor of protein-lysine methyltransferase SMYD2. J Biol Chem. 2015;290:13641-13653. doi: 10.1074/jbc.M114.626861.
    • (2015) J Biol Chem , vol.290 , pp. 13641-13653
    • Nguyen, H.1    Allali-Hassani, A.2    Antonysamy, S.3
  • 35
    • 84924059414 scopus 로고    scopus 로고
    • The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor (TNF-) production
    • Xu G, Liu G, Xiong S, Liu H, Chen X, Zheng B. The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor (TNF-) production. J Biol Chem. 2015;290:5414-5423. doi: 10.1074/jbc.M114.610345.
    • (2015) J Biol Chem , vol.290 , pp. 5414-5423
    • Xu, G.1    Liu, G.2    Xiong, S.3    Liu, H.4    Chen, X.5    Zheng, B.6
  • 36
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • Deloukas P, Kanoni S, Willenborg C, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013;45:25-33
    • (2013) Nat Genet , vol.45 , pp. 25-33
    • Deloukas, P.1    Kanoni, S.2    Willenborg, C.3
  • 38
  • 40
    • 84933679127 scopus 로고    scopus 로고
    • Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: What have we learned from GWASs?
    • Hannou SA, Wouters K, Paumelle R, Staels B. Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs? Trends Endocrinol Metab. 2015;26:176-184. doi: 10.1016/j.tem.2015.01.008.
    • (2015) Trends Endocrinol Metab , vol.26 , pp. 176-184
    • Hannou, S.A.1    Wouters, K.2    Paumelle, R.3    Staels, B.4
  • 41
    • 34249848165 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm as a complex multifactorial disease: Interactions of polymorphisms of inflammatory genes, features of autoimmunity, and current status of MMPs
    • Pearce WH, Shively VP. Abdominal aortic aneurysm as a complex multifactorial disease: interactions of polymorphisms of inflammatory genes, features of autoimmunity, and current status of MMPs. Ann N Y Acad Sci. 2006;1085:117-132. doi: 10.1196/annals.1383.025.
    • (2006) Ann N y Acad Sci , vol.1085 , pp. 117-132
    • Pearce, W.H.1    Shively, V.P.2
  • 42
    • 84954398045 scopus 로고    scopus 로고
    • Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci
    • Coleman C, Quinn EM, Ryan AW, et al. Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci. Eur J Hum Genet. 2016;24:291-297. doi: 10.1038/ejhg.2015.87.
    • (2016) Eur J Hum Genet , vol.24 , pp. 291-297
    • Coleman, C.1    Quinn, E.M.2    Ryan, A.W.3
  • 46
    • 33747379850 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines
    • Choke E, Thompson MM, Dawson J, Wilson WR, Sayed S, Loftus IM, Cockerill GW. Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines. Arterioscler Thromb Vasc Biol. 2006;26:2077-2082. doi: 10.1161/01.ATV.0000234944.22509.f9.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2077-2082
    • Choke, E.1    Thompson, M.M.2    Dawson, J.3    Wilson, W.R.4    Sayed, S.5    Loftus, I.M.6    Cockerill, G.W.7
  • 47
    • 76349107344 scopus 로고    scopus 로고
    • Site specificity of aneurysmal disease
    • Norman PE, Powell JT. Site specificity of aneurysmal disease. Circulation. 2010;121:560-568. doi: 10.1161/CIRCULATIONAHA.109.880724.
    • (2010) Circulation , vol.121 , pp. 560-568
    • Norman, P.E.1    Powell, J.T.2
  • 49
    • 84906078639 scopus 로고    scopus 로고
    • SMYD proteins: Key regulators in skeletal and cardiac muscle development and function
    • Du SJ, Tan X, Zhang J. SMYD proteins: key regulators in skeletal and cardiac muscle development and function. Anat Rec (Hoboken). 2014;297:1650-1662. doi: 10.1002/ar.22972.
    • (2014) Anat Rec (Hoboken) , vol.297 , pp. 1650-1662
    • Du, S.J.1    Tan, X.2    Zhang, J.3
  • 50
    • 84927946719 scopus 로고    scopus 로고
    • Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in mice
    • Qi J, Yang P, Yi B, Huo Y, Chen M, Zhang J, Sun J. Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in mice. Am J Physiol Heart Circ Physiol. 2015;308:H841-H852. doi: 10.1152/ajpheart.00470.2014.
    • (2015) Am J Physiol Heart Circ Physiol , vol.308 , pp. H841-H852
    • Qi, J.1    Yang, P.2    Yi, B.3    Huo, Y.4    Chen, M.5    Zhang, J.6    Sun, J.7
  • 51
    • 84880067125 scopus 로고    scopus 로고
    • SMYD2 is induced during cell differentiation and participates in early development
    • Sesé B, Barrero MJ, Fabregat MC, Sander V, Izpisua Belmonte JC. SMYD2 is induced during cell differentiation and participates in early development. Int J Dev Biol. 2013;57:357-364. doi: 10.1387/ijdb.130051j.i.
    • (2013) Int J Dev Biol , vol.57 , pp. 357-364
    • Sesé, B.1    Barrero, M.J.2    Fabregat, M.C.3    Sander, V.4    Izpisua Belmonte, J.C.5
  • 52
  • 53
    • 77954772383 scopus 로고    scopus 로고
    • Short stature is associated with coronary heart disease: A systematic review of the literature and a meta-analysis
    • Paajanen TA, Oksala NK, Kuukasjärvi P, Karhunen PJ. Short stature is associated with coronary heart disease: a systematic review of the literature and a meta-analysis. Eur Heart J. 2010;31:1802-1809. doi: 10.1093/eurheartj/ehq155.
    • (2010) Eur Heart J , vol.31 , pp. 1802-1809
    • Paajanen, T.A.1    Oksala, N.K.2    Kuukasjärvi, P.3    Karhunen, P.J.4
  • 54
    • 84928021248 scopus 로고    scopus 로고
    • Genetically determined height and coronary artery disease
    • CARDioGRAM+C4D Consortium
    • Nelson CP, Hamby SE, Saleheen D, et al; CARDioGRAM+C4D Consortium. Genetically determined height and coronary artery disease. N Engl J Med. 2015;372:1608-1618. doi: 10.1056/NEJMoa1404881.
    • (2015) N Engl J Med , vol.372 , pp. 1608-1618
    • Nelson, C.P.1    Hamby, S.E.2    Saleheen, D.3
  • 55
    • 84886730249 scopus 로고    scopus 로고
    • A pilot study on low-density lipoprotein receptor-related protein-1 in Chinese patients with abdominal aortic aneurysm
    • Chan CY, Chan YC, Cheuk BL, Cheng SW. A pilot study on low-density lipoprotein receptor-related protein-1 in Chinese patients with abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2013;46:549-556. doi: 10.1016/j.ejvs.2013.08.006.
    • (2013) Eur J Vasc Endovasc Surg , vol.46 , pp. 549-556
    • Chan, C.Y.1    Chan, Y.C.2    Cheuk, B.L.3    Cheng, S.W.4
  • 57
    • 85002620872 scopus 로고    scopus 로고
    • Genetic variants in LRP1 and ULK4 are associated with acute aortic dissections
    • GenTAC Investigators; BAVCon Investigators
    • Guo DC, Grove ML, Prakash SK, et al; GenTAC Investigators; BAVCon Investigators. Genetic variants in LRP1 and ULK4 are associated with acute aortic dissections. Am J Hum Genet. 2016;99:762-769. doi: 10.1016/j.ajhg.2016.06.034.
    • (2016) Am J Hum Genet , vol.99 , pp. 762-769
    • Guo, D.C.1    Grove, M.L.2    Prakash, S.K.3
  • 58
    • 79959721099 scopus 로고    scopus 로고
    • Genome-wide association study reveals three susceptibility loci for common migraine in the general population
    • Chasman Di, Schürks M, Anttila V, et al. Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genet. 2011;43:695-698. doi: 10.1038/ng.856.
    • (2011) Nat Genet , vol.43 , pp. 695-698
    • Chasman, D.I.1    Schürks, M.2    Anttila, V.3
  • 60
    • 84949292738 scopus 로고    scopus 로고
    • Fibroblast growth factor-9 activates c-Kit progenitor cells and enhances angiogenesis in the infarcted diabetic heart
    • Singla D, Wang J. Fibroblast growth factor-9 activates c-Kit progenitor cells and enhances angiogenesis in the infarcted diabetic heart. Oxid Med Cell Longev. 2016;2016:5810908. doi: 10.1155/2016/5810908.
    • (2016) Oxid Med Cell Longev , vol.2016 , pp. 5810908
    • Singla, D.1    Wang, J.2
  • 61
    • 84867851011 scopus 로고    scopus 로고
    • Sexual dimorphism of abdominal aortic aneurysms: A striking example of male disadvantage in cardiovascular disease
    • Bloomer LD, Bown MJ, Tomaszewski M. Sexual dimorphism of abdominal aortic aneurysms: a striking example of male disadvantage in cardiovascular disease. Atherosclerosis. 2012;225:22-28. doi: 10.1016/j. atherosclerosis.2012.06.057.
    • (2012) Atherosclerosis , vol.225 , pp. 22-28
    • Bloomer, L.D.1    Bown, M.J.2    Tomaszewski, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.