Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 308, Issue 8, 2015, Pages H841-H852

  Qi, Jia ^a,b   Yang, Ping ^a   Yi, Bing ^b   Huo, Yan ^b   Chen, Ming ^b   Zhang, Jian ^a   Sun, Jianxin ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Aneurysms; Angiotensin II; Apolipoprotein E null mouse; Heat shock protein 90

Indexed keywords

ACETYLCYSTEINE; ADENOSINE DIPHOSPHATE; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR; R 138727; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; 17-(DIMETHYLAMINOETHYLAMINO)-17-DEMETHOXYGELDANAMYCIN; ANGIOTENSIN II; APOLIPOPROTEIN E; BENZOQUINONE DERIVATIVE; CCL2 PROTEIN, MOUSE; HEAT SHOCK PROTEIN 90; I KAPPA B KINASE; MACROCYCLIC LACTAM; MATRIX METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; INFLAMMATION; MALE; MONOCYTE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR SMOOTH MUSCLE; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTIC ANEURYSM; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; MOUSE; NEOVASCULARIZATION (PATHOLOGY); OXIDATIVE STRESS; PATHOPHYSIOLOGY;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM; APOLIPOPROTEINS E; BENZOQUINONES; CELLS, CULTURED; CHEMOKINE CCL2; HSP90 HEAT-SHOCK PROTEINS; I-KAPPA B KINASE; LACTAMS, MACROCYCLIC; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PATHOLOGIC; OXIDATIVE STRESS;

EID: 84927946719     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00470.2014     Document Type: Article

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