Obesity and cancer: Insights for clinicians

Journal of Clinical Oncology

Volumn 34, Issue 35, 2016, Pages 4197-4202

  Goodwin, Pamela J ^a   Chlebowski, Rowan T ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; INSULIN; METFORMIN; SOMATOMEDIN C;

BODY MASS; BODY WEIGHT MANAGEMENT; CANCER INCIDENCE; CANCER LOCALIZATION; CANCER PROGNOSIS; CANCER RISK; DIABETES MELLITUS; DIET; DIGESTIVE SYSTEM CANCER; DISEASE ASSOCIATION; ENERGY BALANCE; ESTROGEN BLOOD LEVEL; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 POSITIVE BREAST CANCER; INSULIN BLOOD LEVEL; LIFESTYLE; MALIGNANT NEOPLASM; MEDICAL ONCOLOGIST; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SARCOPENIC OBESITY; TRIPLE NEGATIVE BREAST CANCER; WEIGHT REDUCTION; COMORBIDITY; FEMALE; MALE; MORTALITY; NEOPLASM; ODDS RATIO; PROGNOSIS; RISK ASSESSMENT; RISK FACTOR;

BODY MASS INDEX; COMORBIDITY; FEMALE; HUMANS; MALE; NEOPLASMS; OBESITY; ODDS RATIO; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS;

EID: 85002131229     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2016.70.5327     Document Type: Review

References (21)

1. Calle EE, Rodriguez C, Walker-Thurmond K, et al: Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:1625-1638, 2003
2. Renehan AG, Tyson M, Egger M, et al: Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies. Lancet 371:569-578, 2008
3. Goodwin PJ, Stambolic V: Impact of the obesity epidemic on cancer. Annu Rev Med 66:281-296, 2015
4. Lauby-Secretan B, Scoccianti C, Loomis D, et al: Body fatness and cancer: Viewpoint of the IARC Working Group. N Engl J Med 375:794-798, 2016
5. Arnold M, Pandeya N, Byrnes G, et al: Global burden of cancer attributable to high body-mass index in 2012: A population-based study. Lancet Oncol 16:36-46, 2015
6. Jiralerspong S, Goodwin PJ: Obesity and breast cancer prognosis: Evidence, challenges, and opportunities. J Clin Oncol 34:4203-4216, 2016
7. Brown JC, Meyerhardt JA: Obesity and energy balance in GI cancer. J Clin Oncol 34:4217-4224, 2016
8. Onstad MA, Schmandt RE, Lu KH: Addressing the role of obesity in endometrial cancer risk, prevention, and treatment. J Clin Oncol 34:4225-4230, 2016
9. Yang L, Drake BF, Colditz GA: Obesity and other cancers. J Clin Oncol 34:4231-4237, 2016
10. Chlebowski RT, Reeves MM: Weight loss randomized intervention trials in female cancer survivors. J Clin Oncol 34:4238-4248, 2016
11. Chlebowski RT, Blackburn GL, Thomson CA, et al: Dietary fat reduction and breast cancer outcome: Interim efficacy results from the Women's Intervention Nutrition Study. J Natl Cancer Inst 98:1767-1776, 2006
12. Chlebowski RT, Blackburn GL, Hoy MK, et al: Survival analyses from the Women's Intervention Nutrition Study (WINS) evaluating dietary fat reduction and breast cancer outcome. J Clin Oncol 26:522, 2008
13. Thomson CA, Van Horn L, Caan BJ, et al: Cancer incidence and mortality during the intervention and postintervention periods of the Women's Health Initiative dietary modification trial. Cancer Epidemiol Biomarkers Prev 23:2924-2935, 2014
14. Shlomai G, Neel B, LeRoith D, et al: Type 2 diabetes mellitus and cancer: The role of pharmacotherapy. J Clin Oncol 34:4261-4269, 2016
15. Lohmann AE, Goodwin PJ, Chlebowski RT, et al: Association of obesity-related metabolic disruptions with cancer risk and outcome. J Clin Oncol 34:4249-4255, 2016
16. Iyengar NM, Gucalp A, Dannenberg AJ, et al: Obesity and cancer mechanisms: Tumor microenvironment and inflammation. J Clin Oncol 34:4270-4276, 2016
17. Hopkins BD, Goncalves MD, Cantley LC: Obesity and cancer mechanisms: Cancer metabolism. J Clin Oncol 34:4277-4283, 2016
18. Renehan AG, Harvie M, Cutress RI, et al: How to manage the obese patient with cancer. J Clin Oncol 34:4284-4294, 2016
19. Alamuddin N, Bakizada Z, Wadden TA: Management of obesity. J Clin Oncol 34:4295-4305, 2016
20. Ligibel JA, Wollins D: The American Society of Clinical Oncology obesity initiative: Rationale, progress, and future directions. J Clin Oncol 34:4256-4260, 2016
21. Siegel RL, Miller KD, Jemal A: Cancer statistics, 2016. CA Cancer J Clin 66:7-30, 2016