-
1
-
-
80054109736
-
How I treat hemophagocytic lymphohistiocytosis
-
Jordan MB, Allen CE, Weitzman S, et al. How I treat hemophagocytic lymphohistiocytosis. Blood. 2011;118(15):4041–4052.
-
(2011)
Blood
, vol.118
, Issue.15
, pp. 4041-4052
-
-
Jordan, M.B.1
Allen, C.E.2
Weitzman, S.3
-
2
-
-
0033520970
-
Perforin gene defects in familial hemophagocytic lymphohistiocytosis
-
Stepp SE, Dufourcq-Lagelouse R, Le Deist F, et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science. 1999;286(5446):1957–1959.
-
(1999)
Science
, vol.286
, Issue.5446
, pp. 1957-1959
-
-
Stepp, S.E.1
Dufourcq-Lagelouse, R.2
Le Deist, F.3
-
3
-
-
10744224641
-
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
-
Feldmann J, Callebaut I, Raposo G, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell. 2003;115(4):461–473.
-
(2003)
Cell
, vol.115
, Issue.4
, pp. 461-473
-
-
Feldmann, J.1
Callebaut, I.2
Raposo, G.3
-
4
-
-
20144363940
-
Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
-
zur Stadt U, Schmidt S, Kasper B, et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet. 2005;14(6):827–834.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.6
, pp. 827-834
-
-
zur Stadt, U.1
Schmidt, S.2
Kasper, B.3
-
5
-
-
70350500464
-
Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
-
zur Stadt U, Rohr J, Seifert W, et al. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. Am J Hum Genet. 2009;85(4):482–492.
-
(2009)
Am J Hum Genet
, vol.85
, Issue.4
, pp. 482-492
-
-
zur Stadt, U.1
Rohr, J.2
Seifert, W.3
-
6
-
-
0344002689
-
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
-
Menasche G, Pastural E, Feldmann J, et al. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet. 2000;25(2):173–176.
-
(2000)
Nat Genet
, vol.25
, Issue.2
, pp. 173-176
-
-
Menasche, G.1
Pastural, E.2
Feldmann, J.3
-
7
-
-
0030293556
-
Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome
-
Nagle DL, Karim MA, Woolf EA, et al. Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome. Nat Genet. 1996;14(3):307–311.
-
(1996)
Nat Genet
, vol.14
, Issue.3
, pp. 307-311
-
-
Nagle, D.L.1
Karim, M.A.2
Woolf, E.A.3
-
8
-
-
17344372694
-
Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
-
Coffey AJ, Brooksbank RA, Brandau O, et al. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet. 1998;20(2):129–135.
-
(1998)
Nat Genet
, vol.20
, Issue.2
, pp. 129-135
-
-
Coffey, A.J.1
Brooksbank, R.A.2
Brandau, O.3
-
9
-
-
13144278345
-
Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome
-
Nichols KE, Harkin DP, Levitz S, et al. Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci USA. 1998;95(23):13765–13770.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.23
, pp. 13765-13770
-
-
Nichols, K.E.1
Harkin, D.P.2
Levitz, S.3
-
10
-
-
0032190081
-
The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
-
Sayos J, Wu C, Morra M, et al. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature. 1998;395(6701):462–469.
-
(1998)
Nature
, vol.395
, Issue.6701
, pp. 462-469
-
-
Sayos, J.1
Wu, C.2
Morra, M.3
-
11
-
-
33750597717
-
XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome
-
Rigaud S, Fondaneche MC, Lambert N, et al. XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome. Nature. 2006;444(7115):110–114.
-
(2006)
Nature
, vol.444
, Issue.7115
, pp. 110-114
-
-
Rigaud, S.1
Fondaneche, M.C.2
Lambert, N.3
-
12
-
-
84936095269
-
The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis
-
Bode SF, Ammann S, Al-Herz W, et al. The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis. Haematologica. 2015;100(7):978–988.
-
(2015)
Haematologica
, vol.100
, Issue.7
, pp. 978-988
-
-
Bode, S.F.1
Ammann, S.2
Al-Herz, W.3
-
13
-
-
0036786375
-
Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
-
Henter JI, Samuelsson-Horne A, Arico M, et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002;100(7):2367–2373.
-
(2002)
Blood
, vol.100
, Issue.7
, pp. 2367-2373
-
-
Henter, J.I.1
Samuelsson-Horne, A.2
Arico, M.3
-
14
-
-
34548384442
-
Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients
-
Mahlaoui N, Ouachee-Chardin M, de Saint Basile G, et al. Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients. Pediatrics. 2007;120(3):e622–e628.
-
(2007)
Pediatrics
, vol.120
, Issue.3
, pp. e622-e628
-
-
Mahlaoui, N.1
Ouachee-Chardin, M.2
de Saint Basile, G.3
-
15
-
-
84870166438
-
Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab
-
Marsh RA, Allen CE, McClain KL, et al. Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab. Pediatr Blood Cancer. 2013;60(1):101–109.
-
(2013)
Pediatr Blood Cancer
, vol.60
, Issue.1
, pp. 101-109
-
-
Marsh, R.A.1
Allen, C.E.2
McClain, K.L.3
-
16
-
-
84948947480
-
Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis
-
Wang Y, Huang W, Hu L, et al. Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis. Blood. 2015;126(19):2186–2192.
-
(2015)
Blood
, vol.126
, Issue.19
, pp. 2186-2192
-
-
Wang, Y.1
Huang, W.2
Hu, L.3
-
17
-
-
33749994238
-
Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis
-
Behrens EM, Kreiger PA, Cherian S, et al. Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis. J Rheumatol. 2006;33(10):2081–2084.
-
(2006)
J Rheumatol
, vol.33
, Issue.10
, pp. 2081-2084
-
-
Behrens, E.M.1
Kreiger, P.A.2
Cherian, S.3
-
18
-
-
78751681576
-
Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients
-
Miettunen PM, Narendran A, Jayanthan A, et al. Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients. Rheumatology. 2011;50(2):417–419.
-
(2011)
Rheumatology
, vol.50
, Issue.2
, pp. 417-419
-
-
Miettunen, P.M.1
Narendran, A.2
Jayanthan, A.3
-
19
-
-
77954244065
-
Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis
-
Strout MP, Seropian S, Berliner N. Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis. Nat Rev Clin Oncol. 2010;7(7):415–420.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.7
, pp. 415-420
-
-
Strout, M.P.1
Seropian, S.2
Berliner, N.3
-
20
-
-
84862843344
-
Adult hemophagocytic lymphohistiocytosis with severe pulmonary hypertension and a novel perforin gene mutation
-
Gerard LM, Xing K, Sherifi I, et al. Adult hemophagocytic lymphohistiocytosis with severe pulmonary hypertension and a novel perforin gene mutation. Int J Hematol. 2012;95(4):445–450.
-
(2012)
Int J Hematol
, vol.95
, Issue.4
, pp. 445-450
-
-
Gerard, L.M.1
Xing, K.2
Sherifi, I.3
-
21
-
-
84978134924
-
A novel targeted approach to the treatment of hemophagocytic lymphohistiocytosis (HLH) with an anti-interferon gamma (IFNγ) monoclonal antibody (mAb), NI-0501: first results from a pilot phase 2 study in children with primary HLH
-
126LBA-3 [abstract]
-
Jordan M, Locatelli F, Allen C, et al. A novel targeted approach to the treatment of hemophagocytic lymphohistiocytosis (HLH) with an anti-interferon gamma (IFNγ) monoclonal antibody (mAb), NI-0501: first results from a pilot phase 2 study in children with primary HLH. Blood. 2015;126:LBA-3 [abstract].
-
(2015)
Blood
-
-
Jordan, M.1
Locatelli, F.2
Allen, C.3
-
22
-
-
85017075036
-
Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis
-
Das R, Guan P, Sprague L, et al. Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis. Blood. 2016;127(13):1666–1675.
-
(2016)
Blood
, vol.127
, Issue.13
, pp. 1666-1675
-
-
Das, R.1
Guan, P.2
Sprague, L.3
-
23
-
-
85007246013
-
Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice
-
Maschalidi S, Sepulveda FE, Garrigue A, et al. Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice. Blood. 2016;128(1):60–71.
-
(2016)
Blood
, vol.128
, Issue.1
, pp. 60-71
-
-
Maschalidi, S.1
Sepulveda, F.E.2
Garrigue, A.3
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