-
1
-
-
0037426058
-
Prostate cancer epidemiology
-
Gronberg H. Prostate cancer epidemiology. Lancet. 2003; 361:859-864.
-
(2003)
Lancet
, vol.361
, pp. 859-864
-
-
Gronberg, H.1
-
3
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer. 2008; 8:755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
5
-
-
45549091414
-
Prostate cancer stem cells: a new target for therapy
-
Maitland NJ, Collins AT. Prostate cancer stem cells: a new target for therapy. J Clin Oncol. 2008; 26:2862-2870.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2862-2870
-
-
Maitland, N.J.1
Collins, A.T.2
-
6
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE. Cells of origin in cancer. Nature. 2011; 469:314-322.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
7
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med. 2011; 17:313-319.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
8
-
-
0035515347
-
The ETS-domain transcription factor family
-
Sharrocks AD. The ETS-domain transcription factor family. Nat Rev Mol Cell Biol. 2001; 2:827-837.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 827-837
-
-
Sharrocks, A.D.1
-
9
-
-
27544515095
-
ETS transcription factors and their emerging roles in human cancer
-
Seth A, Watson DK. ETS transcription factors and their emerging roles in human cancer. Eur J Cancer. 2005; 41:2462-2478.
-
(2005)
Eur J Cancer
, vol.41
, pp. 2462-2478
-
-
Seth, A.1
Watson, D.K.2
-
10
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005; 310:644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
-
11
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, Menon A, Jing X, Cao Q, Han B, Yu J, Wang L, Montie JE, et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature. 2007; 448:595-599.
-
(2007)
Nature
, vol.448
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
-
12
-
-
33645750799
-
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer
-
Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, Helgeson BE, Cao X, Wei JT, Rubin MA, Shah RB, Chinnaiyan AM. TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer. Cancer Res. 2006; 66:3396-3400.
-
(2006)
Cancer Res
, vol.66
, pp. 3396-3400
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Smith, L.R.4
Roulston, D.5
Helgeson, B.E.6
Cao, X.7
Wei, J.T.8
Rubin, M.A.9
Shah, R.B.10
Chinnaiyan, A.M.11
-
14
-
-
84897406127
-
A promoter-level mammalian expression atlas
-
Consortium F, the RP, Clst, Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, et al. A promoter-level mammalian expression atlas. Nature. 2014; 507:462-470.
-
(2014)
Nature
, vol.507
, pp. 462-470
-
-
Kawaji, H.1
Rehli, M.2
Baillie, J.K.3
de Hoon, M.J.4
Haberle, V.5
Lassmann, T.6
Kulakovskiy, I.V.7
Lizio, M.8
Itoh, M.9
-
15
-
-
42949154207
-
Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer
-
Cangemi R, Mensah A, Albertini V, Jain A, Mello-Grand M, Chiorino G, Catapano CV, Carbone GM. Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer. Oncogene. 2008; 27:2877-2885.
-
(2008)
Oncogene
, vol.27
, pp. 2877-2885
-
-
Cangemi, R.1
Mensah, A.2
Albertini, V.3
Jain, A.4
Mello-Grand, M.5
Chiorino, G.6
Catapano, C.V.7
Carbone, G.M.8
-
16
-
-
77956285565
-
ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer
-
Kunderfranco P, Mello-Grand M, Cangemi R, Pellini S, Mensah A, Albertini V, Malek A, Chiorino G, Catapano CV, Carbone GM. ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer. PLoS One. 2010; 5:e10547.
-
(2010)
PLoS One
, vol.5
-
-
Kunderfranco, P.1
Mello-Grand, M.2
Cangemi, R.3
Pellini, S.4
Mensah, A.5
Albertini, V.6
Malek, A.7
Chiorino, G.8
Catapano, C.V.9
Carbone, G.M.10
-
17
-
-
84861903355
-
ESE3/EHF controls epithelial cell differentiation and its loss leads to prostate tumors with mesenchymal and stem-like features
-
Albino D, Longoni N, Curti L, Mello-Grand M, Pinton S, Civenni G, Thalmann G, D'Ambrosio G, Sarti M, Sessa F, Chiorino G, Catapano CV, Carbone GM. ESE3/EHF controls epithelial cell differentiation and its loss leads to prostate tumors with mesenchymal and stem-like features. Cancer Res. 2012; 72:2889-2900.
-
(2012)
Cancer Res
, vol.72
, pp. 2889-2900
-
-
Albino, D.1
Longoni, N.2
Curti, L.3
Mello-Grand, M.4
Pinton, S.5
Civenni, G.6
Thalmann, G.7
D'Ambrosio, G.8
Sarti, M.9
Sessa, F.10
Chiorino, G.11
Catapano, C.V.12
Carbone, G.M.13
-
18
-
-
84976892453
-
Activation of the Lin28/let7 axis by loss of ESE3/EHF promotes a tumorigenic and stem-like phenotype in prostate cancer
-
Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM. Activation of the Lin28/let7 axis by loss of ESE3/EHF promotes a tumorigenic and stem-like phenotype in prostate cancer. Cancer Res. 2016.
-
(2016)
Cancer Res
-
-
Albino, D.1
Civenni, G.2
Dallavalle, C.3
Roos, M.4
Jahns, H.5
Curti, L.6
Rossi, S.7
Pinton, S.8
D'Ambrosio, G.9
Sessa, F.10
Hall, J.11
Catapano, C.V.12
Carbone, G.M.13
-
19
-
-
85009854382
-
Expression of STAT3 in Prostate Cancer Metastases
-
Don-Doncow N, Marginean F, Coleman I, Nelson PS, Ehrnstrom R, Krzyzanowska A, Morrissey C, Hellsten R, Bjartell A. Expression of STAT3 in Prostate Cancer Metastases. Eur Urol. 2016.
-
(2016)
Eur Urol
-
-
Don-Doncow, N.1
Marginean, F.2
Coleman, I.3
Nelson, P.S.4
Ehrnstrom, R.5
Krzyzanowska, A.6
Morrissey, C.7
Hellsten, R.8
Bjartell, A.9
-
20
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell. 2010; 18:11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
Arora, V.K.7
Kaushik, P.8
Cerami, E.9
Reva, B.10
Antipin, Y.11
Mitsiades, N.12
Landers, T.13
-
21
-
-
84879496408
-
Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy
-
Erho N, Crisan A, Vergara IA, Mitra AP, Ghadessi M, Buerki C, Bergstralh EJ, Kollmeyer T, Fink S, Haddad Z, Zimmermann B, Sierocinski T, Ballman KV, et al. Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy. PLoS One. 2013; 8:e66855.
-
(2013)
PLoS One
, vol.8
-
-
Erho, N.1
Crisan, A.2
Vergara, I.A.3
Mitra, A.P.4
Ghadessi, M.5
Buerki, C.6
Bergstralh, E.J.7
Kollmeyer, T.8
Fink, S.9
Haddad, Z.10
Zimmermann, B.11
Sierocinski, T.12
Ballman, K.V.13
-
22
-
-
84902168138
-
Inflammation and prostate cancer: the role of interleukin 6 (IL-6)
-
Nguyen DP, Li J, Tewari AK. Inflammation and prostate cancer: the role of interleukin 6 (IL-6). BJU Int. 2014; 113:986-992.
-
(2014)
BJU Int
, vol.113
, pp. 986-992
-
-
Nguyen, D.P.1
Li, J.2
Tewari, A.K.3
-
23
-
-
35948995750
-
Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer
-
Sasser AK, Sullivan NJ, Studebaker AW, Hendey LF, Axel AE, Hall BM. Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer. FASEB J. 2007; 21:3763-3770.
-
(2007)
FASEB J
, vol.21
, pp. 3763-3770
-
-
Sasser, A.K.1
Sullivan, N.J.2
Studebaker, A.W.3
Hendey, L.F.4
Axel, A.E.5
Hall, B.M.6
-
24
-
-
39649113108
-
Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival
-
Wegiel B, Bjartell A, Culig Z, Persson JL. Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival. Int J Cancer. 2008; 122:1521-1529.
-
(2008)
Int J Cancer
, vol.122
, pp. 1521-1529
-
-
Wegiel, B.1
Bjartell, A.2
Culig, Z.3
Persson, J.L.4
-
25
-
-
47649125632
-
Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis
-
Wegiel B, Bjartell A, Tuomela J, Dizeyi N, Tinzl M, Helczynski L, Nilsson E, Otterbein LE, Harkonen P, Persson JL. Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis. J Natl Cancer Inst. 2008; 100:1022-1036.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1022-1036
-
-
Wegiel, B.1
Bjartell, A.2
Tuomela, J.3
Dizeyi, N.4
Tinzl, M.5
Helczynski, L.6
Nilsson, E.7
Otterbein, L.E.8
Harkonen, P.9
Persson, J.L.10
-
26
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci USA. 2011; 108:1397-1402.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 1397-1402
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Wang, G.3
Struhl, K.4
-
27
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell. 2009; 139:693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
28
-
-
84921283229
-
Mechanisms and applications of interleukins in cancer immunotherapy
-
Anestakis D, Petanidis S, Kalyvas S, Nday CM, Tsave O, Kioseoglou E, Salifoglou A. Mechanisms and applications of interleukins in cancer immunotherapy. Int J Mol Sci. 2015; 16:1691-1710.
-
(2015)
Int J Mol Sci
, vol.16
, pp. 1691-1710
-
-
Anestakis, D.1
Petanidis, S.2
Kalyvas, S.3
Nday, C.M.4
Tsave, O.5
Kioseoglou, E.6
Salifoglou, A.7
-
29
-
-
84928568835
-
IL-6 as a keystone cytokine in health and disease
-
Hunter CA, Jones SA. IL-6 as a keystone cytokine in health and disease. Nat Immunol. 2015; 16:448-457.
-
(2015)
Nat Immunol
, vol.16
, pp. 448-457
-
-
Hunter, C.A.1
Jones, S.A.2
-
30
-
-
84880894958
-
ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kappaB and drives prostate cancer progression
-
Longoni N, Sarti M, Albino D, Civenni G, Malek A, Ortelli E, Pinton S, Mello-Grand M, Ostano P, D'Ambrosio G, Sessa F, Garcia-Escudero R, Thalmann GN, et al. ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kappaB and drives prostate cancer progression. Cancer Res. 2013; 73:4533-4547.
-
(2013)
Cancer Res
, vol.73
, pp. 4533-4547
-
-
Longoni, N.1
Sarti, M.2
Albino, D.3
Civenni, G.4
Malek, A.5
Ortelli, E.6
Pinton, S.7
Mello-Grand, M.8
Ostano, P.9
D'Ambrosio, G.10
Sessa, F.11
Garcia-Escudero, R.12
Thalmann, G.N.13
-
31
-
-
84923911592
-
Proinflammatory cytokine interleukin-6 in prostate carcinogenesis
-
Culig Z. Proinflammatory cytokine interleukin-6 in prostate carcinogenesis. Am J Clin Exp Urol. 2014; 2:231-238.
-
(2014)
Am J Clin Exp Urol
, vol.2
, pp. 231-238
-
-
Culig, Z.1
-
32
-
-
67649537602
-
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells
-
Napoli S, Pastori C, Magistri M, Carbone GM, Catapano CV. Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells. Embo J. 2009; 28:1708-1719.
-
(2009)
Embo J
, vol.28
, pp. 1708-1719
-
-
Napoli, S.1
Pastori, C.2
Magistri, M.3
Carbone, G.M.4
Catapano, C.V.5
-
33
-
-
9444235088
-
Co-operative functions between nuclear factors NFkappaB and CCAT/enhancer-binding protein-beta (C/EBP-beta) regulate the IL-6 promoter in autocrine human prostate cancer cells
-
Xiao W, Hodge DR, Wang L, Yang X, Zhang X, Farrar WL. Co-operative functions between nuclear factors NFkappaB and CCAT/enhancer-binding protein-beta (C/EBP-beta) regulate the IL-6 promoter in autocrine human prostate cancer cells. Prostate. 2004; 61:354-370.
-
(2004)
Prostate
, vol.61
, pp. 354-370
-
-
Xiao, W.1
Hodge, D.R.2
Wang, L.3
Yang, X.4
Zhang, X.5
Farrar, W.L.6
-
34
-
-
77954619670
-
Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805
-
Baffert F, Regnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chene P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, et al. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. Mol Cancer Ther. 2010; 9:1945-1955.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1945-1955
-
-
Baffert, F.1
Regnier, C.H.2
De Pover, A.3
Pissot-Soldermann, C.4
Tavares, G.A.5
Blasco, F.6
Brueggen, J.7
Chene, P.8
Drueckes, P.9
Erdmann, D.10
Furet, P.11
Gerspacher, M.12
Lang, M.13
-
35
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
-
Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker SR, Bloushtain-Qimron N, Kim JJ, Choudhury SA, Maruyama R, Wu Z, Gonen M, Mulvey LA, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. J Clin Invest. 2011; 121:2723-2735.
-
(2011)
J Clin Invest
, vol.121
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
Shipitsin, M.4
Schemme, J.5
Walker, S.R.6
Bloushtain-Qimron, N.7
Kim, J.J.8
Choudhury, S.A.9
Maruyama, R.10
Wu, Z.11
Gonen, M.12
Mulvey, L.A.13
-
36
-
-
84863723010
-
The mutational landscape of lethal castration-resistant prostate cancer
-
Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, Khan AP, Quist MJ, Jing X, Lonigro RJ, Brenner JC, Asangani IA, Ateeq B, Chun SY, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature. 2012; 487:239-243.
-
(2012)
Nature
, vol.487
, pp. 239-243
-
-
Grasso, C.S.1
Wu, Y.M.2
Robinson, D.R.3
Cao, X.4
Dhanasekaran, S.M.5
Khan, A.P.6
Quist, M.J.7
Jing, X.8
Lonigro, R.J.9
Brenner, J.C.10
Asangani, I.A.11
Ateeq, B.12
Chun, S.Y.13
-
37
-
-
84927621581
-
Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells
-
Fossum SL, Mutolo MJ, Yang R, Dang H, O'Neal WK, Knowles MR, Leir SH, Harris A. Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells. Nucleic Acids Res. 2014; 42:13588-13598.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 13588-13598
-
-
Fossum, S.L.1
Mutolo, M.J.2
Yang, R.3
Dang, H.4
O'Neal, W.K.5
Knowles, M.R.6
Leir, S.H.7
Harris, A.8
-
38
-
-
77952103123
-
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
-
Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell. 2010; 17:443-454.
-
(2010)
Cancer Cell
, vol.17
, pp. 443-454
-
-
Yu, J.1
Mani, R.S.2
Cao, Q.3
Brenner, C.J.4
Cao, X.5
Wang, X.6
Wu, L.7
Li, J.8
Hu, M.9
Gong, Y.10
Cheng, H.11
Laxman, B.12
Vellaichamy, A.13
|