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Volumn 4, Issue , 2016, Pages

The microbiota in bronchoalveolar lavage from young children with chronic lung disease includes taxa present in both the oropharynx and nasopharynx

Author keywords

Bronchoalveolar lavage; Lower airways; Microbiota; Nasopharynx; Oropharynx; Paediatric lung disease; Upper airways

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CEFTRIAXONE; COTRIMOXAZOLE; FLUCLOXACILLIN; RNA 16S; ROXITHROMYCIN; BACTERIAL DNA; RIBOSOME DNA;

EID: 84997207326     PISSN: None     EISSN: 20492618     Source Type: Journal    
DOI: 10.1186/s40168-016-0182-1     Document Type: Article
Times cited : (141)

References (59)
  • 1
    • 84929493450 scopus 로고    scopus 로고
    • Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals
    • Bassis CM, Erb-Downward JR, Dickson RP, Freeman CM, Schmidt TM, Young VB, et al. Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals. MBio. 2015;6(2):e00037.
    • (2015) MBio. , vol.6 , Issue.2
    • Bassis, C.M.1    Erb-Downward, J.R.2    Dickson, R.P.3    Freeman, C.M.4    Schmidt, T.M.5    Young, V.B.6
  • 2
    • 84906673705 scopus 로고    scopus 로고
    • The role of the microbiome in exacerbations of chronic lung diseases
    • Dickson RP, Martinez FJ, Huffnagle GB. The role of the microbiome in exacerbations of chronic lung diseases. Lancet. 2014;384(9944):691-702.
    • (2014) Lancet. , vol.384 , Issue.9944 , pp. 691-702
    • Dickson, R.P.1    Martinez, F.J.2    Huffnagle, G.B.3
  • 3
    • 84943748936 scopus 로고    scopus 로고
    • Induced sputum in young healthy children with cystic fibrosis
    • Forton J. Induced sputum in young healthy children with cystic fibrosis. Paediatr Respir Rev. 2015;16 Suppl 1:6-8.
    • (2015) Paediatr Respir Rev. , vol.16 , pp. 6-8
    • Forton, J.1
  • 6
    • 0030001433 scopus 로고    scopus 로고
    • Bronchoalveolar lavage or oropharyngeal cultures to identify lower respiratory pathogens in infants with cystic fibrosis
    • Armstrong DS, Grimwood K, Carlin JB, Carzino R, Olinsky A, Phelan PD. Bronchoalveolar lavage or oropharyngeal cultures to identify lower respiratory pathogens in infants with cystic fibrosis. Pediatr Pulmonol. 1996;21(5):267-75.
    • (1996) Pediatr Pulmonol. , vol.21 , Issue.5 , pp. 267-275
    • Armstrong, D.S.1    Grimwood, K.2    Carlin, J.B.3    Carzino, R.4    Olinsky, A.5    Phelan, P.D.6
  • 7
    • 84997255680 scopus 로고    scopus 로고
    • Upper airway viruses and bacteria detection in clinical pneumonia in a population with high nasal colonisation do not relate to clinical signs
    • Chang AB, Smith-Vaughan HC, Sloots TP, Valery PC, Whiley D, Beissbarth J, et al. Upper airway viruses and bacteria detection in clinical pneumonia in a population with high nasal colonisation do not relate to clinical signs. Pneumonia. 2015;6:48-56.
    • (2015) Pneumonia. , vol.6 , pp. 48-56
    • Chang, A.B.1    Smith-Vaughan, H.C.2    Sloots, T.P.3    Valery, P.C.4    Whiley, D.5    Beissbarth, J.6
  • 9
    • 84911888639 scopus 로고    scopus 로고
    • Directly sampling the lung of a young child with cystic fibrosis reveals diverse microbiota
    • Brown PS, Pope CE, Marsh RL, Qin X, McNamara S, Gibson R, et al. Directly sampling the lung of a young child with cystic fibrosis reveals diverse microbiota. Ann Am Thorac Soc. 2014;11(7):1049-55.
    • (2014) Ann Am Thorac Soc. , vol.11 , Issue.7 , pp. 1049-1055
    • Brown, P.S.1    Pope, C.E.2    Marsh, R.L.3    Qin, X.4    McNamara, S.5    Gibson, R.6
  • 10
    • 33746255217 scopus 로고    scopus 로고
    • Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism analysis to compare bacterial communities in sputum and mouthwash samples from patients with cystic fibrosis
    • Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Kehagia V, et al. Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism analysis to compare bacterial communities in sputum and mouthwash samples from patients with cystic fibrosis. J Clin Microbiol. 2006;44(7):2601-4.
    • (2006) J Clin Microbiol. , vol.44 , Issue.7 , pp. 2601-2604
    • Rogers, G.B.1    Carroll, M.P.2    Serisier, D.J.3    Hockey, P.M.4    Jones, G.5    Kehagia, V.6
  • 11
    • 84865285995 scopus 로고    scopus 로고
    • Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota
    • Goddard AF, Staudinger BJ, Dowd SE, Joshi-Datar A, Wolcott RD, Aitken ML, et al. Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota. PNAS. 2012;109(34):13769-74.
    • (2012) PNAS. , vol.109 , Issue.34 , pp. 13769-13774
    • Goddard, A.F.1    Staudinger, B.J.2    Dowd, S.E.3    Joshi-Datar, A.4    Wolcott, R.D.5    Aitken, M.L.6
  • 13
    • 84961291390 scopus 로고    scopus 로고
    • Comparison of microbiomes from different niches of upper and lower airways in children and adolescents with cystic fibrosis
    • Boutin S, Graeber SY, Weitnauer M, Panitz J, Stahl M, Clausznitzer D, et al. Comparison of microbiomes from different niches of upper and lower airways in children and adolescents with cystic fibrosis. PLoS One. 2015;10(1):e0116029.
    • (2015) PLoS One. , vol.10 , Issue.1
    • Boutin, S.1    Graeber, S.Y.2    Weitnauer, M.3    Panitz, J.4    Stahl, M.5    Clausznitzer, D.6
  • 14
    • 84916206478 scopus 로고    scopus 로고
    • Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children
    • Biesbroek G, Tsivtsivadze E, Sanders EA, Montijn R, Veenhoven RH, Keijser BJ, et al. Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children. Am J Respir Crit Care Med. 2014;190(11):1283-92.
    • (2014) Am J Respir Crit Care Med. , vol.190 , Issue.11 , pp. 1283-1292
    • Biesbroek, G.1    Tsivtsivadze, E.2    Sanders, E.A.3    Montijn, R.4    Veenhoven, R.H.5    Keijser, B.J.6
  • 15
    • 77958049683 scopus 로고    scopus 로고
    • Epidemiology of nasopharyngeal carriage of respiratory bacterial pathogens in children and adults: cross-sectional surveys in a population with high rates of pneumococcal disease
    • Mackenzie G, Leach A, Carapetis J, Fisher J, Morris P. Epidemiology of nasopharyngeal carriage of respiratory bacterial pathogens in children and adults: cross-sectional surveys in a population with high rates of pneumococcal disease. BMC Infect Dis. 2010;10(1):304.
    • (2010) BMC Infect Dis. , vol.10 , Issue.1 , pp. 304
    • Mackenzie, G.1    Leach, A.2    Carapetis, J.3    Fisher, J.4    Morris, P.5
  • 16
    • 78449278858 scopus 로고    scopus 로고
    • Respiratory bacterial pathogens in the nasopharynx and lower airways of Australian indigenous children with bronchiectasis
    • Hare KM, Grimwood K, Leach AJ, Smith-Vaughan H, Torzillo PJ, Morris PS, et al. Respiratory bacterial pathogens in the nasopharynx and lower airways of Australian indigenous children with bronchiectasis. J Pediatr. 2010;157(6):1001-5.
    • (2010) J Pediatr. , vol.157 , Issue.6 , pp. 1001-1005
    • Hare, K.M.1    Grimwood, K.2    Leach, A.J.3    Smith-Vaughan, H.4    Torzillo, P.J.5    Morris, P.S.6
  • 18
    • 84929513174 scopus 로고    scopus 로고
    • The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development
    • Teo SM, Mok D, Pham K, Kusel M, Serralha M, Troy N, et al. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development. Cell Host Microbe. 2015;17(5):704-15.
    • (2015) Cell Host Microbe. , vol.17 , Issue.5 , pp. 704-715
    • Teo, S.M.1    Mok, D.2    Pham, K.3    Kusel, M.4    Serralha, M.5    Troy, N.6
  • 19
    • 84867176924 scopus 로고    scopus 로고
    • Upper airways microbiota in antibiotic-naive wheezing and healthy infants from the tropics of rural Ecuador
    • Cardenas PA, Cooper PJ, Cox MJ, Chico M, Arias C, Moffatt MF, et al. Upper airways microbiota in antibiotic-naive wheezing and healthy infants from the tropics of rural Ecuador. PLoS One. 2012;7(10):e46803.
    • (2012) PLoS One. , vol.7 , Issue.10
    • Cardenas, P.A.1    Cooper, P.J.2    Cox, M.J.3    Chico, M.4    Arias, C.5    Moffatt, M.F.6
  • 20
    • 84887916383 scopus 로고    scopus 로고
    • Increased risk of pneumonia and bronchiolitis after bacterial colonization of the airways as neonates
    • Vissing NH, Chawes BL, Bisgaard H. Increased risk of pneumonia and bronchiolitis after bacterial colonization of the airways as neonates. Am J Respir Crit Care Med. 2013;188(10):1246-52.
    • (2013) Am J Respir Crit Care Med. , vol.188 , Issue.10 , pp. 1246-1252
    • Vissing, N.H.1    Chawes, B.L.2    Bisgaard, H.3
  • 21
    • 77957828103 scopus 로고    scopus 로고
    • Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study
    • Bisgaard H, Hermansen MN, Bonnelykke K, Stokholm J, Baty F, Skytt NL, et al. Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study. BMJ. 2010;341:c4978.
    • (2010) BMJ. , vol.341
    • Bisgaard, H.1    Hermansen, M.N.2    Bonnelykke, K.3    Stokholm, J.4    Baty, F.5    Skytt, N.L.6
  • 22
    • 84870903108 scopus 로고    scopus 로고
    • Quantitative PCR of ear discharge from indigenous Australian children with acute otitis media with perforation supports a role for Alloiococcus otitidis as a secondary pathogen
    • Marsh RL, Binks MJ, Beissbarth J, Christensen P, Morris PS, Leach AJ, et al. Quantitative PCR of ear discharge from indigenous Australian children with acute otitis media with perforation supports a role for Alloiococcus otitidis as a secondary pathogen. BMC Ear Nose Throat Disord. 2012;12:11.
    • (2012) BMC Ear Nose Throat Disord. , vol.12 , pp. 11
    • Marsh, R.L.1    Binks, M.J.2    Beissbarth, J.3    Christensen, P.4    Morris, P.S.5    Leach, A.J.6
  • 23
    • 0036146824 scopus 로고    scopus 로고
    • Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set
    • Nadkarni MA, Martin FE, Jacques NA, Hunter N. Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set. Microbiology. 2002;148(1):257-66.
    • (2002) Microbiology. , vol.148 , Issue.1 , pp. 257-266
    • Nadkarni, M.A.1    Martin, F.E.2    Jacques, N.A.3    Hunter, N.4
  • 24
    • 84920644670 scopus 로고    scopus 로고
    • Reagent and laboratory contamination can critically impact sequence-based microbiome analyses
    • Salter SJ, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, et al. Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol. 2014;12:87.
    • (2014) BMC Biol. , vol.12 , pp. 87
    • Salter, S.J.1    Cox, M.J.2    Turek, E.M.3    Calus, S.T.4    Cookson, W.O.5    Moffatt, M.F.6
  • 25
    • 84863292680 scopus 로고    scopus 로고
    • Deep sequencing analyses of low density microbial communities: working at the boundary of accurate microbiota detection
    • Biesbroek G, Sanders EAM, Roeselers G, Wang X, Caspers MPM, Trzcinski K, et al. Deep sequencing analyses of low density microbial communities: working at the boundary of accurate microbiota detection. PLoS One. 2012;7(3):e32942.
    • (2012) PLoS One. , vol.7 , Issue.3
    • Biesbroek, G.1    Sanders, E.A.M.2    Roeselers, G.3    Wang, X.4    Caspers, M.P.M.5    Trzcinski, K.6
  • 26
    • 85131755527 scopus 로고    scopus 로고
    • Deriving accurate microbiota profiles from human samples with low bacterial content through post-sequencing processing of Illumina MiSeq data
    • Jervis-Bardy J, Leong LE, Marri S, Smith RJ, Choo JM, Smith-Vaughan HC, et al. Deriving accurate microbiota profiles from human samples with low bacterial content through post-sequencing processing of Illumina MiSeq data. Microbiome. 2015;3:19.
    • (2015) Microbiome. , vol.3 , pp. 19
    • Jervis-Bardy, J.1    Leong, L.E.2    Marri, S.3    Smith, R.J.4    Choo, J.M.5    Smith-Vaughan, H.C.6
  • 28
    • 84938799471 scopus 로고    scopus 로고
    • The lung microbiome: new principles for respiratory bacteriology in health and disease
    • Dickson RP, Huffnagle GB. The lung microbiome: new principles for respiratory bacteriology in health and disease. PLoS Pathog. 2015;11(7):e1004923.
    • (2015) PLoS Pathog. , vol.11 , Issue.7
    • Dickson, R.P.1    Huffnagle, G.B.2
  • 30
    • 15544385921 scopus 로고    scopus 로고
    • The cost of seasonal respiratory illnesses in Australian children: the dominance of patient and family costs and implications for vaccine use
    • Lambert S, O'Grady KA, Gabriel S, Carter R, Nolan T. The cost of seasonal respiratory illnesses in Australian children: the dominance of patient and family costs and implications for vaccine use. Commun Dis Intell Q Rep. 2004;28(4):510-6.
    • (2004) Commun Dis Intell Q Rep. , vol.28 , Issue.4 , pp. 510-516
    • Lambert, S.1    O'Grady, K.A.2    Gabriel, S.3    Carter, R.4    Nolan, T.5
  • 31
    • 84884515392 scopus 로고    scopus 로고
    • Comparison of the prevalence of common bacterial pathogens in the oropharynx and nasopharynx of Gambian infants
    • Odutola A, Antonio M, Owolabi O, Bojang A, Foster-Nyarko E, Donkor S, et al. Comparison of the prevalence of common bacterial pathogens in the oropharynx and nasopharynx of Gambian infants. PLoS One. 2013;8(9):e75558.
    • (2013) PLoS One. , vol.8 , Issue.9
    • Odutola, A.1    Antonio, M.2    Owolabi, O.3    Bojang, A.4    Foster-Nyarko, E.5    Donkor, S.6
  • 32
    • 84880955519 scopus 로고    scopus 로고
    • Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric radiologically confirmed community acquired pneumonia following PCV7 introduction in Switzerland
    • Chappuy H, Keitel K, Gehri M, Tabin R, Robitaille L, Raymond F, et al. Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric radiologically confirmed community acquired pneumonia following PCV7 introduction in Switzerland. BMC Infect Dis. 2013;13:357.
    • (2013) BMC Infect Dis. , vol.13 , pp. 357
    • Chappuy, H.1    Keitel, K.2    Gehri, M.3    Tabin, R.4    Robitaille, L.5    Raymond, F.6
  • 33
    • 84897443242 scopus 로고    scopus 로고
    • Nasopharyngeal Proteobacteria are associated with viral etiology and acute wheezing in children with severe bronchiolitis
    • Hyde ER, Petrosino JF, Piedra PA, Camargo Jr CA, Espinola JA, Mansbach JM. Nasopharyngeal Proteobacteria are associated with viral etiology and acute wheezing in children with severe bronchiolitis. J Allergy Clin Immunol. 2014;133(4):1220-2.
    • (2014) J Allergy Clin Immunol. , vol.133 , Issue.4 , pp. 1220-1222
    • Hyde, E.R.1    Petrosino, J.F.2    Piedra, P.A.3    Camargo, C.A.4    Espinola, J.A.5    Mansbach, J.M.6
  • 34
    • 84888023135 scopus 로고    scopus 로고
    • P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs
    • Ciofu O, Johansen HK, Aanaes K, Wassermann T, Alhede M, von Buchwald C, et al. P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs. J Cyst Fibros. 2013;12(6):729-36.
    • (2013) J Cyst Fibros. , vol.12 , Issue.6 , pp. 729-736
    • Ciofu, O.1    Johansen, H.K.2    Aanaes, K.3    Wassermann, T.4    Alhede, M.5    von Buchwald, C.6
  • 35
    • 84884366610 scopus 로고    scopus 로고
    • Bacterial sinusitis can be a focus for initial lung colonisation and chronic lung infection in patients with cystic fibrosis
    • Aanaes K. Bacterial sinusitis can be a focus for initial lung colonisation and chronic lung infection in patients with cystic fibrosis. J Cyst Fibros. 2013;12 Suppl 2:S1-20.
    • (2013) J Cyst Fibros. , vol.12 , pp. S1-20
    • Aanaes, K.1
  • 36
    • 0027997882 scopus 로고
    • Bacterial colonization of the nasopharynx predicts very early onset and persistence of otitis media in Australian aboriginal infants
    • Leach AJ, Boswell JB, Asche V, Nienhuys TG, Mathews JD. Bacterial colonization of the nasopharynx predicts very early onset and persistence of otitis media in Australian aboriginal infants. Pediatr Infect Dis J. 1994;13(11):983-9.
    • (1994) Pediatr Infect Dis J. , vol.13 , Issue.11 , pp. 983-989
    • Leach, A.J.1    Boswell, J.B.2    Asche, V.3    Nienhuys, T.G.4    Mathews, J.D.5
  • 39
    • 84939148132 scopus 로고    scopus 로고
    • Effects of vaccination with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) on the nasopharyngeal microbiome of Kenyan toddlers
    • Feazel LM, Santorico SA, Robertson CE, Bashraheil M, Scott JA, Frank DN, et al. Effects of vaccination with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) on the nasopharyngeal microbiome of Kenyan toddlers. PLoS One. 2015;10(6):e0128064.
    • (2015) PLoS One. , vol.10 , Issue.6
    • Feazel, L.M.1    Santorico, S.A.2    Robertson, C.E.3    Bashraheil, M.4    Scott, J.A.5    Frank, D.N.6
  • 40
    • 84926244984 scopus 로고    scopus 로고
    • Dynamics of the nasal microbiota in infancy: a prospective cohort study
    • Mika M, Mack I, Korten I, Qi W, Aebi S, Frey U, et al. Dynamics of the nasal microbiota in infancy: a prospective cohort study. J Allergy Clin Immunol. 2015;135(4):905-12. e11.
    • (2015) J Allergy Clin Immunol. , vol.135 , Issue.4
    • Mika, M.1    Mack, I.2    Korten, I.3    Qi, W.4    Aebi, S.5    Frey, U.6
  • 41
    • 0033835782 scopus 로고    scopus 로고
    • Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis
    • Hill AT, Campbell EJ, Hill SL, Bayley DL, Stockley RA. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis. Am J Med. 2000;109(4):288-95.
    • (2000) Am J Med. , vol.109 , Issue.4 , pp. 288-295
    • Hill, A.T.1    Campbell, E.J.2    Hill, S.L.3    Bayley, D.L.4    Stockley, R.A.5
  • 43
    • 0035092678 scopus 로고    scopus 로고
    • Evaluation of a medium (STGG) for transport and optimal recovery of Streptococcus pneumoniae from nasopharyngeal secretions collected during field studies
    • O'Brien KL, Bronsdon MA, Dagan R, Yagupsky P, Janco J, Elliott J, et al. Evaluation of a medium (STGG) for transport and optimal recovery of Streptococcus pneumoniae from nasopharyngeal secretions collected during field studies. J Clin Microbiol. 2001;39(3):1021-4.
    • (2001) J Clin Microbiol. , vol.39 , Issue.3 , pp. 1021-1024
    • O'Brien, K.L.1    Bronsdon, M.A.2    Dagan, R.3    Yagupsky, P.4    Janco, J.5    Elliott, J.6
  • 44
    • 84891951124 scopus 로고    scopus 로고
    • Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group
    • Satzke C, Turner P, Virolainen-Julkunen A, Adrian PV, Antonio M, Hare KM, et al. Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group. Vaccine. 2013;32(1):165-79.
    • (2013) Vaccine. , vol.32 , Issue.1 , pp. 165-179
    • Satzke, C.1    Turner, P.2    Virolainen-Julkunen, A.3    Adrian, P.V.4    Antonio, M.5    Hare, K.M.6
  • 46
    • 77957665989 scopus 로고    scopus 로고
    • Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand
    • Chang AB, Bell SC, Byrnes CA, Grimwood K, Holmes PW, King PT, et al. Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand. Med J Aust. 2010;193(6):356-65.
    • (2010) Med J Aust. , vol.193 , Issue.6 , pp. 356-365
    • Chang, A.B.1    Bell, S.C.2    Byrnes, C.A.3    Grimwood, K.4    Holmes, P.W.5    King, P.T.6
  • 47
    • 79958703757 scopus 로고    scopus 로고
    • Bronchoarterial ratio on high-resolution CT scan of the chest in children without pulmonary pathology: need to redefine bronchial dilatation
    • Kapur N, Masel JP, Watson D, Masters IB, Chang AB. Bronchoarterial ratio on high-resolution CT scan of the chest in children without pulmonary pathology: need to redefine bronchial dilatation. Chest. 2011;139(6):1445-50.
    • (2011) Chest. , vol.139 , Issue.6 , pp. 1445-1450
    • Kapur, N.1    Masel, J.P.2    Watson, D.3    Masters, I.B.4    Chang, A.B.5
  • 48
    • 84872845171 scopus 로고    scopus 로고
    • Bronchoscopy contributes to the clinical management of indigenous children newly diagnosed with bronchiectasis
    • Pizzutto SJ, Grimwood K, Bauert P, Schutz KL, Yerkovich ST, Upham JW, et al. Bronchoscopy contributes to the clinical management of indigenous children newly diagnosed with bronchiectasis. Pediatr Pulmonol. 2012;48(1):67-73.
    • (2012) Pediatr Pulmonol. , vol.48 , Issue.1 , pp. 67-73
    • Pizzutto, S.J.1    Grimwood, K.2    Bauert, P.3    Schutz, K.L.4    Yerkovich, S.T.5    Upham, J.W.6
  • 51
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: open-source, platform-independent, communitysupported software for describing and comparing microbial communities
    • Schloss PD, Westcott SL, Ryabin T, Hall JR, Hartmann M, Hollister EB, et al. Introducing mothur: open-source, platform-independent, communitysupported software for describing and comparing microbial communities. Appl Environ Microbiol. 2009;75(23):7537-41.
    • (2009) Appl Environ Microbiol. , vol.75 , Issue.23 , pp. 7537-7541
    • Schloss, P.D.1    Westcott, S.L.2    Ryabin, T.3    Hall, J.R.4    Hartmann, M.5    Hollister, E.B.6
  • 52
    • 83355173006 scopus 로고    scopus 로고
    • Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies
    • Schloss PD, Gevers D, Westcott SL. Reducing the effects of PCR amplification and sequencing artifacts on 16S rRNA-based studies. PLoS One. 2011;6(12): e27310.
    • (2011) PLoS One. , vol.6 , Issue.12
    • Schloss, P.D.1    Gevers, D.2    Westcott, S.L.3
  • 53
    • 84997339178 scopus 로고    scopus 로고
    • Accessed May 2014.
    • Mothur 454-SOP. http://www.mothur.org/wiki/454_SOP. Accessed May 2014.
  • 54
    • 84997508671 scopus 로고    scopus 로고
    • Accessed May 2014.
    • Mothur Silve Reference Files. http://mothur.org/wiki/Silva_reference:files. Accessed May 2014.
  • 55
    • 84997256579 scopus 로고    scopus 로고
    • Accessed Sept 2015.
    • BLASTn. http://blast.ncbi.nlm.nih.gov/Blast.cgi. Accessed Sept 2015.
  • 56
    • 79951780811 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria
    • R Core Team. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL https://www.Rproject.org/.
    • R: a language and environment for statistical computing


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