-
1
-
-
11144242211
-
Timeline: chemotherapy and the war on cancer
-
Chabner BA., Roberts TG., Jr. Timeline: chemotherapy and the war on cancer. Nat Rev Cancer 2005;5:65-72.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 65-72
-
-
Chabner, B.A.1
Roberts, T.G.2
-
2
-
-
41349099104
-
Cancer statistics
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., Thun MJ. Cancer statistics., 2008. CA Cancer J Clin 2008;58:71-96.
-
(2008)
CA Cancer J Clin
, vol.2008
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
3
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang YH., Hertzberg R., Hecht S., Liu LF. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985;260:14873-8.
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
4
-
-
0029919598
-
Irinotecan is an active agent in untreated patients with metastatic colorectal cancer
-
Conti JA., Kemeny NE., Saltz LB., Huang Y., Tong WP., Chou TC., Sun M., Pulliam S., Gonzalez C. Irinotecan is an active agent in untreated patients with metastatic colorectal cancer. J Clin Oncol 1996;14:709-15.
-
(1996)
J Clin Oncol
, vol.14
, pp. 709-715
-
-
Conti, J.A.1
Kemeny, N.E.2
Saltz, L.B.3
Huang, Y.4
Tong, W.P.5
Chou, T.C.6
Sun, M.7
Pulliam, S.8
Gonzalez, C.9
-
5
-
-
67650759744
-
Evolving treatment of advanced colon cancer
-
Segal NH., Saltz LB. Evolving treatment of advanced colon cancer. Annu Rev Med 2009;60:207-19.
-
(2009)
Annu Rev Med
, vol.60
, pp. 207-219
-
-
Segal, N.H.1
Saltz, L.B.2
-
6
-
-
84934436050
-
Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy
-
Bosch TM. Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy. Methods Mol Biol 2008;448:63-76.
-
(2008)
Methods Mol Biol
, vol.448
, pp. 63-76
-
-
Bosch, T.M.1
-
7
-
-
71549170831
-
Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoino-sitide 3-kinase/Akt signaling pathway
-
Arafa El-SA, Zhu Q., Barakat BM., Wani G., Zhao Q., El-Mahdy MA., Wani AA. Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoino-sitide 3-kinase/Akt signaling pathway. Cancer Res 2009;69: 8910-7.
-
(2009)
Cancer Res
, vol.69
, pp. 8910-8917
-
-
Arafa, E.-S.1
Zhu, Q.2
Barakat, B.M.3
Wani, G.4
Zhao, Q.5
El-Mahdy, M.A.6
Wani, A.A.7
-
9
-
-
52949096859
-
The function of Stat3 in tumor cells and their microenvironment
-
Groner B., Lucks P., Borghouts C. The function of Stat3 in tumor cells and their microenvironment. Semin Cell Dev Biol 2008;19:341-50.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 341-350
-
-
Groner, B.1
Lucks, P.2
Borghouts, C.3
-
10
-
-
77950391697
-
Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers?
-
Masuda M., Wakasaki T., Suzui M., Toh S., Joe AK., Weinstein IB. Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers? Curr Cancer Drug Targets 2010;10:117-26.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 117-126
-
-
Masuda, M.1
Wakasaki, T.2
Suzui, M.3
Toh, S.4
Joe, A.K.5
Weinstein, I.B.6
-
11
-
-
33845865865
-
The STAT3 oncogene as a predictive marker of drug resistance
-
Barré B., Vigneron A., Perkins N., Roninson IB., Gamelin E., Coqueret O. The STAT3 oncogene as a predictive marker of drug resistance. Trends Mol Med 2007;13:4-11.
-
(2007)
Trends Mol Med
, vol.13
, pp. 4-11
-
-
Barré, B.1
Vigneron, A.2
Perkins, N.3
Roninson, I.B.4
Gamelin, E.5
Coqueret, O.6
-
12
-
-
33748992592
-
Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer
-
Duan Z., Foster R., Bell DA., Mahoney J., Wolak K., Vaidya A., Hampel C., Lee H., Seiden MV. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. Clin Cancer Res 2006;12:5055-63.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5055-5063
-
-
Duan, Z.1
Foster, R.2
Bell, D.A.3
Mahoney, J.4
Wolak, K.5
Vaidya, A.6
Hampel, C.7
Lee, H.8
Seiden, M.V.9
-
13
-
-
77955983410
-
SellierH, deCarné Tréces son S., Vigneron A., Bernard AC., Gamelin E., Barré B., Coqueret O. The cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibition
-
Courapied S., SellierH, deCarné Tréces son S., Vigneron A., Bernard AC., Gamelin E., Barré B., Coqueret O. The cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibition. J Biol Chem 2010;285:26765-78.
-
(2010)
J Biol Chem
, vol.285
, pp. 26765-26778
-
-
Courapied, S.1
-
14
-
-
59849101586
-
Function of mitochondrial Stat3 in cellular respiration
-
Wegrzyn J., Potla R., Chwae YJ., Sepuri NB., Zhang Q., Koeck T., Derecka M., Szczepanek K., Szelag M., Gornicka A., Moh A., Moghaddas S., Chen Q., Bobbili S., Cichy J., Dulak J., Baker DP., Wolfman A., Stuehr D., Hassan MO., Fu XY., Avadhani N., Drake JI., Fawcett P., Lesnefsky EJ., Larner AC. Function of mitochondrial Stat3 in cellular respiration. Science 2009;323: 793-7.
-
(2009)
Science
, vol.323
, pp. 793-797
-
-
Wegrzyn, J.1
Potla, R.2
Chwae, Y.J.3
Sepuri, N.B.4
Zhang, Q.5
Koeck, T.6
Derecka, M.7
Szczepanek, K.8
Szelag, M.9
Gornicka, A.10
Moh, A.11
Moghaddas, S.12
Chen, Q.13
Bobbili, S.14
Cichy, J.15
Dulak, J.16
Baker, D.P.17
Wolfman, A.18
Stuehr, D.19
Hassan, M.O.20
Fu, X.Y.21
Avadhani, N.22
Drake, J.I.23
Fawcett, P.24
Lesnefsky, E.J.25
Larner, A.C.26
more..
-
15
-
-
38849086135
-
The EGFR-STAT3 oncogenic pathway up-regulates the Emel endonuclease to reduce DNA damage after topoisomerase I inhibition
-
Vigneron A., Gamelin E., Coqueret O. The EGFR-STAT3 oncogenic pathway up-regulates the Emel endonuclease to reduce DNA damage after topoisomerase I inhibition. Cancer Res 2008;68:815-25.
-
(2008)
Cancer Res
, vol.68
, pp. 815-825
-
-
Vigneron, A.1
Gamelin, E.2
Coqueret, O.3
-
16
-
-
40349111099
-
Monomeric recombinant peptide aptamers are required for efficient intracel-lular uptake and target inhibition
-
Borghouts C., Kunz C., Delis N., Groner B. Monomeric recombinant peptide aptamers are required for efficient intracel-lular uptake and target inhibition. Mol Cancer Res 2008;6: 267-81.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 267-281
-
-
Borghouts, C.1
Kunz, C.2
Delis, N.3
Groner, B.4
-
17
-
-
3543070089
-
The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apopto-sis in tumor cells
-
Nagel-Wolfrum K., Buerger C., Wittig I., Butz K., Hoppe-Seyler F., Groner B. The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apopto-sis in tumor cells. Mol Cancer Res 2004;2:170-82.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 170-182
-
-
Nagel-Wolfrum, K.1
Buerger, C.2
Wittig, I.3
Butz, K.4
Hoppe-Seyler, F.5
Groner, B.6
-
18
-
-
33750982120
-
a small-molecule inhibitor of STAT3 activation and dimerization
-
Schust J., Sperl B., Hollis A., Mayer TU., Berg T. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol 2006;13:1235-42.
-
(2006)
Chem Biol
, vol.13
, pp. 1235-1242
-
-
Schust, J.1
Sperl, B.2
Hollis, A.3
Mayer, T.U.4
Berg, T.5
-
19
-
-
60849106339
-
Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models
-
Pitts TM., Morrow M., Kaufman SA., Tentler JJ., Eckhardt SG. Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models. Mol Cancer Ther 2009;8:342-9.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 342-349
-
-
Pitts, T.M.1
Morrow, M.2
Kaufman, S.A.3
Tentler, J.J.4
Eckhardt, S.G.5
-
20
-
-
81955167415
-
Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells
-
Bose D., Zimmerman LJ., Pierobon M., Petricoin E., Tozzi F., Parikh A., Fan F., Dallas N., Xia L., Gaur P., Samuel S., Liebler DC., Ellis LM. Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells. Br J Cancer 2011;105:1759-67.
-
(2011)
Br J Cancer
, vol.105
, pp. 1759-1767
-
-
Bose, D.1
Zimmerman, L.J.2
Pierobon, M.3
Petricoin, E.4
Tozzi, F.5
Parikh, A.6
Fan, F.7
Dallas, N.8
Xia, L.9
Gaur, P.10
Samuel, S.11
Liebler, D.C.12
Ellis, L.M.13
-
21
-
-
62449205665
-
2nd, Samuel S., Kim MP., Lim SJ., Ellis LM. Chemoresistant colorectal cancer cells., the cancer stem cell phenotype., and increased sensitivity to insulin-like growth factor-I receptor inhibition
-
Dallas NA., Xia L., Fan F., Gray MJ., Gaur P., van Buren G., 2nd, Samuel S., Kim MP., Lim SJ., Ellis LM. Chemoresistant colorectal cancer cells., the cancer stem cell phenotype., and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009;69:1951-7.
-
(2009)
Cancer Res
, vol.69
, pp. 1951-1957
-
-
Dallas, N.A.1
Xia, L.2
Fan, F.3
Gray, M.J.4
Gaur, P.5
van Buren, G.6
-
22
-
-
28544449918
-
SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells
-
George JA., Chen T., Taylor CC. SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. Cancer Res 2005;65:10381-8.
-
(2005)
Cancer Res
, vol.65
, pp. 10381-10388
-
-
George, J.A.1
Chen, T.2
Taylor, C.C.3
-
23
-
-
84860400947
-
Src family kinases and paclitaxel sensitivity
-
Le XF., Bast RC., Jr. Src family kinases and paclitaxel sensitivity. Cancer Biol Ther 2011;12:260-9.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 260-269
-
-
Le XF, R.C.1
-
24
-
-
84855876635
-
STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH/CD133 stem cell-like human colon cancer cells
-
Lin L., Fuchs J., Li C., Olson V., Bekaii-Saab T., Lin J. STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH/CD133 stem cell-like human colon cancer cells. Biochem Biophys Res Commun 2011;416:246-51.
-
(2011)
Biochem Biophys Res Commun
, vol.416
, pp. 246-251
-
-
Lin, L.1
Fuchs, J.2
Li, C.3
Olson, V.4
Bekaii-Saab, T.5
Lin, J.6
-
25
-
-
84355161519
-
Inhibition of activated Stat3 reverses drug resistance to chemo-therapeutic agents in gastric cancer cells
-
Huang S., Chen M., Shen Y., Shen W., Guo H., Gao Q., Zou X. Inhibition of activated Stat3 reverses drug resistance to chemo-therapeutic agents in gastric cancer cells. Cancer Lett 2012;315: 198-205.
-
(2012)
Cancer Lett
, vol.315
, pp. 198-205
-
-
Huang, S.1
Chen, M.2
Shen, Y.3
Shen, W.4
Guo, H.5
Gao, Q.6
Zou, X.7
|