Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy

Oncotarget

Volumn 7, Issue 46, 2016, Pages 74612-74629

  Yamada, Eijiro ^a   Okada, Shuichi ^a   Bastie, Claire C ^b   Vatish, Manu ^d   Nakajima, Yasuyo ^a   Shibusawa, Ryo ^a   Ozawa, Atsushi ^a   Pessin, Jeffrey E ^c   Yamada, Masanobu ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

AMPK; Autophagy; Fyn; TNF

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE; PROTEIN KINASE FYN; TUMOR NECROSIS FACTOR; TYROSINE; ADENOSINE PHOSPHATE;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE MUTATION; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL LINE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; SKELETAL MUSCLE;

ADENOSINE MONOPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE; ENZYME ACTIVATION; HUMANS; MICE; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FYN; STRESS, PHYSIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84996743312     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11916     Document Type: Article

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