Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response

Journal of Cell Science

Volumn 129, Issue 22, 2016, Pages 4190-4199

  Steen, Håkan C ^a   Kotredes, Kevin P ^a   Nogusa, Shoko ^b   Harris, Michele Y ^a   Balachandran, Siddharth ^b   Gamero, Ana M ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Interferon; JAK1; Serine phosphorylation; STAT2; Vesicular stomatitis; Virus infection

Indexed keywords

ALANINE; ALPHA INTERFERON; JANUS KINASE; SERINE; STAT2 PROTEIN; ANTIVIRUS AGENT;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RESPONSE; DNA MICROARRAY; EMBRYO; GENE; HUMAN; HUMAN CELL; INTERFERON STIMULATED GENE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TRANSACTIVATION; VESICULOVIRUS; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL FRACTIONATION; CHEMISTRY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL PROLIFERATION; HUMANS; INTERFERON-ALPHA; JANUS KINASES; MASS SPECTROMETRY; MICE; MODELS, BIOLOGICAL; PHOSPHORYLATION; SERINE; STAT2 TRANSCRIPTION FACTOR; SUBCELLULAR FRACTIONS; VESICULOVIRUS;

EID: 84995977107     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.185421     Document Type: Article

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