The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

Science

Volumn 354, Issue 6314, 2016, Pages 909-912

  Barau, Joan ^a   Teissandier, Aurélie ^a,b   Zamudio, Natasha ^a,g   Roy, Stéphanie ^c   Nalesso, Valérie ^d,e,f   Hérault, Yann ^d,e,f   Guillou, Florian ^c   Bourc'his, Déborah ^a  

^a INSTITUT CURIE   (France)

^b PSL RESEARCH UNIVERSITY   (France)

^c UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e CNRS   (France)

^f INSERM   (France)

^g WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3C; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNMT3L PROTEIN, MOUSE; ETHYLNITROSOUREA; RETROPOSON;

CELLS AND CELL COMPONENTS; DEVELOPMENTAL BIOLOGY; DNA; ENZYME ACTIVITY; EVOLUTIONARY BIOLOGY; FERTILITY; GENE; GENOME; MACHINERY; MALE; METHYLATION; RODENT;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; GERM CELL; GERM LINE; MALE; MALE FERTILITY; MOUSE; NONHUMAN; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROMOTER REGION; RETROPOSON; ANIMAL; CELL LINE; CHEMICALLY INDUCED; CLASSIFICATION; DRUG EFFECTS; ENZYMOLOGY; GENE INACTIVATION; GENETIC EPIGENESIS; GENETICS; HYPOGONADISM; METABOLISM; MUTAGENESIS; PATHOLOGY; PHYLOGENY; SPERMATOGONIUM; TESTIS;

MAMMALIA; RODENTIA;

ANIMALS; CELL LINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; ETHYLNITROSOUREA; GENE KNOCKOUT TECHNIQUES; HYPOGONADISM; MALE; MICE; MUTAGENESIS; PHYLOGENY; PROMOTER REGIONS, GENETIC; RETROELEMENTS; SPERMATOGONIA; TESTIS;

EID: 84995959575     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aah5143     Document Type: Article

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