메뉴 건너뛰기




Volumn 20, Issue 4, 2017, Pages 591-601

Intratumor stromal proportion predicts aggressive phenotype of gastric signet ring cell carcinomas

Author keywords

Cancer associated fibroblast; Gastric cancer; Intratumor stromal proportion; Prognosis; Signet ring cell carcinoma

Indexed keywords

ADULT; AGED; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER CELL; CANCER GROWTH; CANCER STAGING; CELL MIGRATION; DISEASE FREE SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GASTROINTESTINAL STROMAL TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; METASTASIS; OVERALL SURVIVAL; PATHOLOGY; PERINEURAL INVASION; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROGNOSTIC ASSESSMENT; RNA SEQUENCE; SIGNET RING CARCINOMA; TUMOR INVASION; TUMOR VOLUME; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; PROGNOSIS; STOMACH TUMOR; TUMOR MICROENVIRONMENT; VERY ELDERLY; YOUNG ADULT;

EID: 84995755029     PISSN: 14363291     EISSN: 14363305     Source Type: Journal    
DOI: 10.1007/s10120-016-0669-2     Document Type: Article
Times cited : (56)

References (34)
  • 1
    • 80052021537 scopus 로고    scopus 로고
    • Tangled fibroblasts in tumor-stroma interactions
    • COI: 1:CAS:528:DC%2BC3MXhtVKlsr3K, PID: 21469145
    • Liu M, Xu J, Deng H. Tangled fibroblasts in tumor-stroma interactions. Int J Cancer. 2011;129:1795–805.
    • (2011) Int J Cancer , vol.129 , pp. 1795-1805
    • Liu, M.1    Xu, J.2    Deng, H.3
  • 2
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • COI: 1:CAS:528:DC%2BD1MXivFCjsLg%3D, PID: 19279573
    • Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer. 2009;9:239–52.
    • (2009) Nat Rev Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 3
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • COI: 1:CAS:528:DC%2BC3sXhslCmsrjL, PID: 24202395
    • Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med. 2013;19:1423–37.
    • (2013) Nat Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 4
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • COI: 1:CAS:528:DC%2BC38XktFOgtbw%3D, PID: 22397650
    • Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med. 2012;366:883–92.
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3    Larkin, J.4    Endesfelder, D.5    Gronroos, E.6
  • 5
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: functions of cells recruited to the tumor microenvironment
    • COI: 1:CAS:528:DC%2BC38Xkt1ykt7w%3D, PID: 22439926
    • Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell. 2012;21:309–22.
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 6
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 84865693829 scopus 로고    scopus 로고
    • Tumor-stroma ratio is an independent predictor for survival in esophageal squamous cell carcinoma
    • PID: 22843085
    • Wang K, Ma W, Wang J, Yu L, Zhang X, Wang Z, et al. Tumor-stroma ratio is an independent predictor for survival in esophageal squamous cell carcinoma. J Thorac Oncol. 2012;7:1457–61.
    • (2012) J Thorac Oncol , vol.7 , pp. 1457-1461
    • Wang, K.1    Ma, W.2    Wang, J.3    Yu, L.4    Zhang, X.5    Wang, Z.6
  • 8
    • 79151474811 scopus 로고    scopus 로고
    • Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients
    • PID: 20361254
    • de Kruijf EM, van Nes JG, van de Velde CJ, Putter H, Smit VT, Liefers GJ, et al. Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients. Breast Cancer Res Treat. 2011;125:687–96.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 687-696
    • de Kruijf, E.M.1    van Nes, J.G.2    van de Velde, C.J.3    Putter, H.4    Smit, V.T.5    Liefers, G.J.6
  • 9
    • 34547913802 scopus 로고    scopus 로고
    • The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage
    • PID: 17726261
    • Mesker WE, Junggeburt JM, Szuhai K, de Heer P, Morreau H, Tanke HJ, et al. The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage. Cell Oncol. 2007;29:387–98.
    • (2007) Cell Oncol , vol.29 , pp. 387-398
    • Mesker, W.E.1    Junggeburt, J.M.2    Szuhai, K.3    de Heer, P.4    Morreau, H.5    Tanke, H.J.6
  • 10
    • 0027161705 scopus 로고
    • Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia
    • COI: 1:STN:280:DyaK3s3psFSrsQ%3D%3D, PID: 8515656
    • Ronnov-Jessen L, Petersen OW. Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia. Lab Invest. 1993;68:696–707.
    • (1993) Lab Invest , vol.68 , pp. 696-707
    • Ronnov-Jessen, L.1    Petersen, O.W.2
  • 11
    • 84877065511 scopus 로고    scopus 로고
    • Fibroblasts as architects of cancer pathogenesis
    • COI: 1:CAS:528:DC%2BC38Xhs1KqsrrN, PID: 23123598
    • Marsh T, Pietras K, McAllister SS. Fibroblasts as architects of cancer pathogenesis. Biochim Biophys Acta. 2013;1832:1070–8.
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 1070-1078
    • Marsh, T.1    Pietras, K.2    McAllister, S.S.3
  • 13
    • 84857640591 scopus 로고    scopus 로고
    • Cancer associated fibroblasts: the dark side of the coin
    • COI: 1:CAS:528:DC%2BC3MXms1Kntrc%3D, PID: 21984967
    • Cirri P, Chiarugi P. Cancer associated fibroblasts: the dark side of the coin. Am J Cancer Res. 2011;1:482–97.
    • (2011) Am J Cancer Res. , vol.1 , pp. 482-497
    • Cirri, P.1    Chiarugi, P.2
  • 14
    • 73449102148 scopus 로고    scopus 로고
    • Signet ring cell histology is an independent predictor of poor prognosis in gastric adenocarcinoma regardless of tumoral clinical presentation
    • PID: 19855261
    • Piessen G, Messager M, Leteurtre E, Jean-Pierre T, Mariette C. Signet ring cell histology is an independent predictor of poor prognosis in gastric adenocarcinoma regardless of tumoral clinical presentation. Ann Surg. 2009;250:878–87.
    • (2009) Ann Surg , vol.250 , pp. 878-887
    • Piessen, G.1    Messager, M.2    Leteurtre, E.3    Jean-Pierre, T.4    Mariette, C.5
  • 15
    • 84970002304 scopus 로고    scopus 로고
    • Differential prognostic implications of gastric signet ring cell carcinoma: stage adjusted analysis from a single high-volume center in Asia
    • Chon HJ, Hyung WJ, Kim C, Park S, Kim JH, Park CH, et al. Differential prognostic implications of gastric signet ring cell carcinoma: stage adjusted analysis from a single high-volume center in Asia. Ann Surg. 2016. doi:10.1097/SLA.0000000000001793.
    • (2016) Ann Surg
    • Chon, H.J.1    Hyung, W.J.2    Kim, C.3    Park, S.4    Kim, J.H.5    Park, C.H.6
  • 16
    • 78650993111 scopus 로고    scopus 로고
    • 7th edition of the AJCC cancer staging manual: stomach
    • PID: 20882416
    • Washington K. 7th edition of the AJCC cancer staging manual: stomach. Ann Surg Oncol. 2010;17:3077–9.
    • (2010) Ann Surg Oncol , vol.17 , pp. 3077-3079
    • Washington, K.1
  • 17
    • 84938701794 scopus 로고    scopus 로고
    • Tumor-stroma ratio is a prognostic factor for survival in hepatocellular carcinoma patients after liver resection or transplantation
    • PID: 25890776
    • Lv Z, Cai X, Weng X, Xiao H, Du C, Cheng J, et al. Tumor-stroma ratio is a prognostic factor for survival in hepatocellular carcinoma patients after liver resection or transplantation. Surgery. 2015;158:142–50.
    • (2015) Surgery , vol.158 , pp. 142-150
    • Lv, Z.1    Cai, X.2    Weng, X.3    Xiao, H.4    Du, C.5    Cheng, J.6
  • 18
    • 84927570856 scopus 로고    scopus 로고
    • Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets
    • COI: 1:CAS:528:DC%2BC2cXpvVars7w%3D, PID: 24935174
    • Qian Z, Zhu G, Tang L, Wang M, Zhang L, Fu J, et al. Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets. Genes Chromosom Cancer. 2014;53:883–94.
    • (2014) Genes Chromosom Cancer , vol.53 , pp. 883-894
    • Qian, Z.1    Zhu, G.2    Tang, L.3    Wang, M.4    Zhang, L.5    Fu, J.6
  • 19
    • 36348994426 scopus 로고    scopus 로고
    • Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer
    • COI: 1:CAS:528:DC%2BD1cXhvFGgsbc%3D, PID: 17978854
    • Berx G, Raspe E, Christofori G, Thiery JP, Sleeman JP. Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis. 2007;24:587–97.
    • (2007) Clin Exp Metastasis , vol.24 , pp. 587-597
    • Berx, G.1    Raspe, E.2    Christofori, G.3    Thiery, J.P.4    Sleeman, J.P.5
  • 20
    • 84939403755 scopus 로고
    • Epithelium-mesenchyme transition during neural crest development
    • COI: 1:STN:280:DyaK283otFSltA%3D%3D
    • Duband JL, Monier F, Delannet M, Newgreen D. Epithelium-mesenchyme transition during neural crest development. Acta Anat (Basel). 1995;154:63–78.
    • (1995) Acta Anat (Basel) , vol.154 , pp. 63-78
    • Duband, J.L.1    Monier, F.2    Delannet, M.3    Newgreen, D.4
  • 21
    • 22244492306 scopus 로고    scopus 로고
    • Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?
    • COI: 1:CAS:528:DC%2BD2MXmt1ehtr0%3D, PID: 16024595, discussion 5995
    • Thompson EW, Newgreen DF, Tarin D. Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Res. 2005;65:5991–5; discussion 5995.
    • (2005) Cancer Res , vol.65 , pp. 5991-5995
    • Thompson, E.W.1    Newgreen, D.F.2    Tarin, D.3
  • 22
    • 80053249325 scopus 로고    scopus 로고
    • Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes
    • COI: 1:CAS:528:DC%2BC3MXhsVSqtbvP, PID: 21854747
    • Sung CO, Lee KW, Han S, Kim SH. Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes. Am J Pathol. 2011;179:1827–38.
    • (2011) Am J Pathol , vol.179 , pp. 1827-1838
    • Sung, C.O.1    Lee, K.W.2    Han, S.3    Kim, S.H.4
  • 23
    • 70349975726 scopus 로고    scopus 로고
    • Direct cancer-stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells
    • COI: 1:STN:280:DC%2BD1MlOkuw%3D%3D, PID: 19773759
    • Semba S, Kodama Y, Ohnuma K, Mizuuchi E, Masuda R, Yashiro M, et al. Direct cancer-stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells. Br J Cancer. 2009;101:1365–73.
    • (2009) Br J Cancer , vol.101 , pp. 1365-1373
    • Semba, S.1    Kodama, Y.2    Ohnuma, K.3    Mizuuchi, E.4    Masuda, R.5    Yashiro, M.6
  • 24
    • 84878302099 scopus 로고    scopus 로고
    • Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value
    • COI: 1:CAS:528:DC%2BC3sXptlSisbo%3D, PID: 23700391
    • Marisa L, de Reynies A, Duval A, Selves J, Gaub MP, Vescovo L, et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med. 2013;10:e1001453.
    • (2013) PLoS Med , vol.10
    • Marisa, L.1    de Reynies, A.2    Duval, A.3    Selves, J.4    Gaub, M.P.5    Vescovo, L.6
  • 25
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • COI: 1:CAS:528:DC%2BC3sXlsl2isLw%3D, PID: 23584089
    • Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat Med. 2013;19:619–25.
    • (2013) Nat Med , vol.19 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, K.3    Collisson, E.A.4    Gibb, W.J.5    Wullschleger, S.6
  • 26
    • 43249121177 scopus 로고    scopus 로고
    • Stromal gene expression predicts clinical outcome in breast cancer
    • COI: 1:CAS:528:DC%2BD1cXlsFCms7w%3D, PID: 18438415
    • Finak G, Bertos N, Pepin F, Sadekova S, Souleimanova M, Zhao H, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med. 2008;14:518–27.
    • (2008) Nat Med , vol.14 , pp. 518-527
    • Finak, G.1    Bertos, N.2    Pepin, F.3    Sadekova, S.4    Souleimanova, M.5    Zhao, H.6
  • 27
    • 38949202980 scopus 로고    scopus 로고
    • Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
    • COI: 1:CAS:528:DC%2BD1cXivVSgt7c%3D, PID: 18044827
    • Bergamaschi A, Tagliabue E, Sorlie T, Naume B, Triulzi T, Orlandi R, et al. Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome. J Pathol. 2008;214:357–67.
    • (2008) J Pathol , vol.214 , pp. 357-367
    • Bergamaschi, A.1    Tagliabue, E.2    Sorlie, T.3    Naume, B.4    Triulzi, T.5    Orlandi, R.6
  • 28
    • 84880315917 scopus 로고    scopus 로고
    • Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer
    • COI: 1:CAS:528:DC%2BC3sXhsVKgsL3I, PID: 22735568
    • Wu Y, Grabsch H, Ivanova T, Tan IB, Murray J, Ooi CH, et al. Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer. Gut. 2013;62:1100–11.
    • (2013) Gut , vol.62 , pp. 1100-1111
    • Wu, Y.1    Grabsch, H.2    Ivanova, T.3    Tan, I.B.4    Murray, J.5    Ooi, C.H.6
  • 29
    • 84925818452 scopus 로고    scopus 로고
    • Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
    • COI: 1:CAS:528:DC%2BC2MXjtFemtr8%3D, PID: 25706628
    • Calon A, Lonardo E, Berenguer-Llergo A, Espinet E, Hernando-Momblona X, Iglesias M, et al. Stromal gene expression defines poor-prognosis subtypes in colorectal cancer. Nat Genet. 2015;47:320–9.
    • (2015) Nat Genet , vol.47 , pp. 320-329
    • Calon, A.1    Lonardo, E.2    Berenguer-Llergo, A.3    Espinet, E.4    Hernando-Momblona, X.5    Iglesias, M.6
  • 30
    • 84907973057 scopus 로고    scopus 로고
    • Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer
    • COI: 1:CAS:528:DC%2BC2cXhsVaksbnN, PID: 25128648
    • Kasashima H, Yashiro M, Kinoshita H, Fukuoka T, Morisaki T, Masuda G, et al. Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer. Cancer Lett. 2014;354:438–46.
    • (2014) Cancer Lett , vol.354 , pp. 438-446
    • Kasashima, H.1    Yashiro, M.2    Kinoshita, H.3    Fukuoka, T.4    Morisaki, T.5    Masuda, G.6
  • 31
    • 84989806021 scopus 로고    scopus 로고
    • TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer
    • COI: 1:CAS:528:DC%2BC2MXhvFKjurzM, PID: 26336878
    • Fujii S, Fujihara A, Natori K, Abe A, Kuboki Y, Higuchi Y, et al. TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer. Cancer Med. 2015;4:1667–78.
    • (2015) Cancer Med , vol.4 , pp. 1667-1678
    • Fujii, S.1    Fujihara, A.2    Natori, K.3    Abe, A.4    Kuboki, Y.5    Higuchi, Y.6
  • 32
    • 84944516706 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics
    • PID: 26259962
    • De Vlieghere E, Verset L, Demetter P, Bracke M, De Wever O. Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics. Virchows Arch. 2015;467:367–82.
    • (2015) Virchows Arch , vol.467 , pp. 367-382
    • De Vlieghere, E.1    Verset, L.2    Demetter, P.3    Bracke, M.4    De Wever, O.5
  • 33
    • 84860390431 scopus 로고    scopus 로고
    • Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
    • COI: 1:CAS:528:DC%2BC3MXht1Ggs73L, PID: 21863023
    • Fuyuhiro Y, Yashiro M, Noda S, Kashiwagi S, Matsuoka J, Doi Y, et al. Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells. Br J Cancer. 2011;105:996–1001.
    • (2011) Br J Cancer , vol.105 , pp. 996-1001
    • Fuyuhiro, Y.1    Yashiro, M.2    Noda, S.3    Kashiwagi, S.4    Matsuoka, J.5    Doi, Y.6
  • 34
    • 84897450600 scopus 로고    scopus 로고
    • Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXlt1eitrk%3D, PID: 24638984
    • Giannelli G, Villa E, Lahn M. Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma. Cancer Res. 2014;74:1890–4.
    • (2014) Cancer Res , vol.74 , pp. 1890-1894
    • Giannelli, G.1    Villa, E.2    Lahn, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.