Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage

Development (Cambridge)

Volumn 143, Issue 22, 2016, Pages 4127-4136

  Shao, Qiang ^a   Herrlinger, Stephanie ^a   Yang, Si Lu ^a   Lai, Fan ^b   Moore, Julie M ^c   Brindley, Melinda A ^c   Chen, Jian Fu ^a  

^a University of Georgia   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

Astrogliosis; Blood brain barrier (BBB); Microcephaly; Microglial activation; ZIKV

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; BRAIN DAMAGE; CELL ACTIVATION; CELL CYCLE ARREST; CONTROLLED STUDY; EMBRYO; MICROCEPHALY; MICROGLIA; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEURAL STEM CELL; NONHUMAN; POSTNATAL GROWTH; PRIORITY JOURNAL; ZIKA FEVER; AEDES; ANGIOGENESIS; ANIMAL; BRAIN; C57BL MOUSE; CENTRAL NERVOUS SYSTEM MALFORMATION; CHLOROCEBUS AETHIOPS; DISEASE MODEL; EMBRYOLOGY; FEMALE; INTRAUTERINE GROWTH RETARDATION; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM MALFORMATION; PHYSIOLOGY; PREGNANCY; VASCULARIZATION; VERO CELL LINE; VIROLOGY; ZIKA VIRUS;

AEDES; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS; CERCOPITHECUS AETHIOPS; DISEASE MODELS, ANIMAL; FEMALE; FETAL GROWTH RETARDATION; MICE; MICE, INBRED C57BL; MICROCEPHALY; NEOVASCULARIZATION, PHYSIOLOGIC; NERVOUS SYSTEM MALFORMATIONS; NEURAL STEM CELLS; NEUROGENESIS; PREGNANCY; VERO CELLS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 84995686670     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.143768     Document Type: Article

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