Zika virus damages the human placental barrier and presents marked fetal neurotropism

Memorias do Instituto Oswaldo Cruz

Volumn 111, Issue 5, 2016, Pages 287-293

  de Noronha, Lucia ^a   Zanluca, Camila ^b   Azevedo, Marina Luize Viola ^a   Luz, Kleber Giovanni ^c   dos Santos, Claudia Nunes Duarte ^b  

^a PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Hofbauer cells; Neurotropism; Transplacental transmission; Zika virus

Indexed keywords

VIRUS RNA;

ADULT; AMNION FLUID; BRAIN; CASE REPORT; EMBRYOLOGY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MICROCEPHALY; NEWBORN; PHYSIOLOGY; PLACENTA; PREGNANCY; VERTICAL TRANSMISSION; VIRAL TROPISM; VIROLOGY; ZIKA VIRUS; ZIKA VIRUS INFECTION;

ADULT; AMNIOTIC FLUID; BRAIN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MALE; MICROCEPHALY; PLACENTA; PREGNANCY; RNA, VIRAL; VIRAL TROPISM; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 84965104185     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/0074-02760160085     Document Type: Article

References (32)

1. Alpert S, Fergerson J, Noël L. Intrauterine West Nile virus: ocular and systemic findings. Am J Ophthalmol. 2003; 136(4): 733-735.
2. Baurakiades E, Martins A, Moreschi NV, Souza C, Abujamra K, Saito A, et al. Histomorphometric and immunohistochemical analysis of infectious agents, T-cell subpopulations and inflammatory adhesion molecules in placentas from HIV-seropositive pregnant women. Diagn Pathol. 2011; 6: 101.
3. Benirchke K, Kaufmann P, Baergen RN. Classifications of villous maldevelopment. In: Benirchke K, Kaufmann P, Baergen RN, editors. Pathology of the human placenta. New York: Springer Science & Business Media; 2006b. p. 502-507.
4. Benirchke K, Kaufmann P, Baergen RN. Infectious diseases. In: Benirchke K, Kaufmann P, Baergen RN, editors. Pathology of the human placenta. New York: Springer Science & Business Media; 2006a. p. 700-715.
5. Boussemart T, Babe P, Sibille G, Neyret C, Berchel C. Prenatal transmission of dengue: two new cases. J Perinatol. 2001; 21(4): 255-257.
6. Brasil P, Pereira JP Jr., Gabaglia CR, Damasceno L, Wakimoto M, Nogueira RMR, et al. Zika virus infection in pregnant women in Rio de Janeiro - Preliminary report. N Engl J Med. 2016; In press.
7. Calvet G, Aguiar RS, Melo ASO, Sampaio SA, de Filippis I, Fabri A, et al. Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis. 2016. doi: http://dx.doi.org/10.1016/S1473-3099(16)00095-5.
8. Chong D, Raboni S, Abujamra K, Marani D, Nogueira M, Tsuchiya L, et al. Respiratory viruses in pediatric necropsies: an immu-nohistochemical study. Pediatr Dev Pathol. 2009; 12(3): 211-216.
9. Dick GWA, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952; 46(5): 509-520.
10. EBC - Empresa Brasil de Comunicação. Casos confirmados de microcefalia sobem para 583, com 67 relacionados ao Zika [Internet]. 2016. Available from: http://agenciabrasil.ebc.com.br/geral/noticia/2016-02/casos-confirmados-de-microcefalia-sobem-pa-ra-583-com-67-relacionados-ao-zika.
11. Greenough A. The TORCH screen and intrauterine infections. Arch Dis Child Fetal Neonatal Ed. 1994; 70(3): F163-F165.
12. Hayes EB. Zika virus outside Africa. Emerg Infect Dis. 2009; 15(9): 1347-1350.
13. Hollidge BS, Gonzalez-Scarano F, Soldan SS. Arboviral encephalitides: transmission, emergence, and pathogenesis. J Neuroimmune Pharmacol. 2010; 5(3): 428-442.
14. Ioos S, Mallet H-P, Goffart IL, Gauthier V, Cardoso T, Herida M. Current Zika virus epidemiology and recent epidemics. Med Mal Infect. 2014; 44(7): 302-307.
15. Kim C, Romero R, Chaemsaithong P, Kim J. Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance. Am J Obstet Gynecol. 2015; 213(Suppl. 4): S53-S69.
16. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, et al. Genetic and serologic properties of Zika virus associated with an epidemic, Yap state, Micronesia, 2007. Emerg Infect Dis. 2008; 14(8): 1232-1239.
17. Laszczyk M, Nowakowska D, Wilczyński J. West Nile virus infection in perinatology. Ginekol Pol. 2007; 78(7): 560-564.
18. Love S, Wiley C. Viral diseases. In: Graham D, Lantos P, editors. Greenfield’s Neuropathology. London: Arnold; 2002. p. 45-48.
19. Martin DA, Muth DA, Brown T, Johnson AJ, Karabatsos N, Roehrig JT. Standardization of immunoglobulin M capture enzyme-linked immunosorbent assays for ruoutine diagnosis of arboviral infections. J Clin Microbiol. 2000; 38(5): 1823-1826.
20. Martines RB, Bhatnagar J, Keating MK, Silva-Flannery L, Muehlenbachs A, Gary J, et al. Evidence of Zika virus infection in brain and placental tissues from two congenitally infected newborns and two fetal losses - Brazil, 2015. MMWR. 2016; 65(6): 1-2.
21. Melo ASO, Malinger G, Ximenes R, Szejnfeld PO, Alves Sampaio S, De Filippis AMB. Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: Tip of the iceberg? Ultra-sound Obstet Gynecol. 2016; 47: 6-7.
22. Misra U, Kalita J. Overview: Japanese encephalitis. Prog Neurobiol. 2010; 91(2): 108-120.
23. Mlakar J, Korva M, Tul N, Popović M, Poljšak-Prijatelj M, Mraz J, et al. Zika virus associated with microcephaly. N Engl J Med. 2016; 374: 951-958.
24. Murray KO, Mertens E, Desprès P. West Nile virus and its emergence in the United States of America. Vet Res. 2010; 41(6): 67.
25. Neu N, Duchon J, Zachariah P. TORCH infections. Clin Perinatol. 2015; 42: 77-103.
26. Oehler E, Watrin L, Larre P, Leparc-Goffart I, Lastere S, Valour F, et al. Zika virus infection complicated by Guillain-Barre syndrome-case report, French Polynesia, December 2013. Euro Surveill. 2014; 19(9): 7-9.
27. PAHO - Pan American Health Organization. Zika virus infection [Internet]. 2016. Available from: http://www.paho.org/hq/index.php?option=com_content&view=article&id=11585&Itemid=41688&lang=en.
28. Pierson TC, Diamond MS. Flaviviruses. In: Knipe DM, Howley PM, editors. Fields virology. Philadelphia: Lippincott Williams & Wilkins; 2013. p. 747-794.
29. Poersch CDO, Pavoni DP, Queiroz MH, Borba L, Goldenberg S, Santos CND, et al. Dengue virus infections: comparison of methods for diagnosing the acute disease. J Clin Virol. 2005; 32(4): 272-277.
30. Sarno M, Sacramento GA, Khouri R, Rosário MS, Costa F, Archanjo G, et al. Zika virus infection and stillbirths: a case of hydrops fetalis, hydranencephaly and fetal demise. PLoS Negl Trop Dis. 2016; 10(2): e0004517.
31. Tsai T, Paul R, Lynberg M, Letson G. Congenital yellow fever virus infection after immunization in pregnancy. J Infect Dis. 1993; 168(6): 1520-1523.
32. Zanluca C, de Melo VCA, Mosimann ALP, dos Santos GIV, dos Santos CND, Luz K. First report of autochthonous transmission of Zika virus in Brazil. Mem Inst Oswaldo Cruz. 2015; 110(4): 569-572.